Lot scheduling problem with idle time transfer between processes to minimize mean flow time is very important because to minimize mean flow time is to minimize work in process. But the problem is NP hard and no polyn...Lot scheduling problem with idle time transfer between processes to minimize mean flow time is very important because to minimize mean flow time is to minimize work in process. But the problem is NP hard and no polynomial algorithm exists to guarantee optimal solution. Based the analysis the mathematical structure of the problem, the paper presents a new heuristic algorithm. Computer simulation shows that the proposed heuristic algorithm performs well in terms of both quality of solution and execution speed.展开更多
To determine the onset and duration of contraflow evacuation, a multi-objective optimization(MOO) model is proposed to explicitly consider both the total system evacuation time and the operation cost. A solution algor...To determine the onset and duration of contraflow evacuation, a multi-objective optimization(MOO) model is proposed to explicitly consider both the total system evacuation time and the operation cost. A solution algorithm that enhances the popular evolutionary algorithm NSGA-II is proposed to solve the model. The algorithm incorporates preliminary results as prior information and includes a meta-model as an alternative to evaluation by simulation. Numerical analysis of a case study suggests that the proposed formulation and solution algorithm are valid, and the enhanced NSGA-II outperforms the original algorithm in both convergence to the true Pareto-optimal set and solution diversity.展开更多
Quantifying the functional relationships relating river discharge and weathering products places key constraints on the negative feedback between the silicate weathering and climate. In this study we analyze the conce...Quantifying the functional relationships relating river discharge and weathering products places key constraints on the negative feedback between the silicate weathering and climate. In this study we analyze the concentration–discharge relationships of weathering products from global rivers using previously compiled time-series datasets for concentrations and discharge from global rivers. To analyze the nature of the covariation between specific discharge and concentrations, we use both a power law equation and a recently developed solute production equation. The solute production equation allows us to quantify weathering efficiency, or the resistance to dilution at high runoff, via the Damkohler coefficient. These results are also compared to those derived using average concentration–discharge pairs.Both the power law exponent and the Damkohler coefficient increase and asymptote as catchments exhibit increasingly chemostatic behavior, resulting in an inverse relationship between the two parameters. We also show that using thedistribution of average concentration–discharge pairs from global rivers, rather than fitting concentration–discharge relationships for each individual river, underestimates global median weathering efficiency by up to a factor of ~10. This study demonstrates the utility of long time-series sampling of global rivers to elucidate controlling processes needed to quantify patterns in global silicate weathering rates.展开更多
In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed sign...In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed signal control at intersections, traffic assignment under traffic flow guidance, and dynamic characteristics of urban traffic management, a tri-level programming model is presented. To reflect the impact of intersection delay on traffic assignment, the lower level model is set as a modified user equilibrium model. The middle level model, which contains several definitional constraints for different phase modes, is built for the traffic signal control optimization. To solve the problem of tide lane management, the upper level model is built up based on nonlinear 0-1 integer programming. A heuristic iterative optimization algorithm(HIOA) is set up to solve the tri-level programming model. The lower level model is solved by method of successive averages(MSA), the middle level model is solved by non-dominated sorting genetic algorithm II(NSGA II), and the upper level model is solved by genetic algorithm(GA). A case study is raised to show the efficiency and applicability of the proposed modelling and computing method.展开更多
We have developed a process for chemical purification of carbon nanotubes for solution-processable thin-film transistors (TFTs) having high mobility. Films of the purified carbon nanotubes fabricated by simple drop ...We have developed a process for chemical purification of carbon nanotubes for solution-processable thin-film transistors (TFTs) having high mobility. Films of the purified carbon nanotubes fabricated by simple drop coating showed carrier mobilities as high as 164 cm2V-1s -1 normalized transconductances of 0.78 Sm-1 and on/off current ratios of 10^6. Such high performance requires the preparation of a suspension of micrometer-long and highly purified semiconducting single-walled carbon nanotubes (SWCNTs). Our purification process includes length and electronic-type selective trapping of SWCNTs using recycling gel filtration with a mixture of surfactants. The results provide an important milestone toward printed high-speed and large-area electronics with roll-to-roll and ink-jet device fabrication.展开更多
Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order t...Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order to inform further studies in Treg cell function. Methods: We separately used magnetic cell sorting and flow cytometry sorting to identify CD4+ CD25+ Treg cells. After magnetic cell separation, we further used flow cytometry to analyze the purity of CD4+ CD25+ Treg cells, trypan blue staining to detect cell viability, and propidium iodide (PI) staining to assess the cell viability. We detected the immune inhibition of CD4+ CD25+ Treg cells in the in vitro proliferation experiments. Results: The results showed that compared to flow cytometry sorting, magnetic cell sorting took more time and effort, but fewer live cells were obtained than with flow cytometry sorting. The CD4+ CD25+ Treg cells, however, obtained with both methods have similar immunosuppressive capacities. Conclusion: The result suggests that both methods can be used in isolating CD4+ CD25+ Treg cells, and one can select the best method according to specific needs and availability of the methodologies.展开更多
As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also bec...As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also becomes the key force which affects the amenity and safety of the train. In the present paper, a simplified CRH380A high-speed train with three carriages is chosen as the model in order to optimize aerodynamic drag of the total train and aerodynamic lift of the trailing car. A constrained mul- ti-objective optimization design of the aerodynamic head shape of high-speed trains based on adaptive non-dominated sorting genetic algorithm is also developed combining local function three-dimensional parametric approach and central Latin hypercube sampling method with maximin criteria based on the iterative local search algorithm. The results show that local function parametric approach can be well applied to optimal design of complex three-dimensional aerodynamic shape, and the adaptive non-dominated sorting genetic algorithm can be more accurate and efficient to find the Pareto front. After optimization the aerodynamic drag of the simplified train with three carriages is reduced by 3.2%, and the lift coefficient of the trailing car by 8.24%, the volume of the streamlined head by 2.16%; the aerodynamic drag of the real prototype CRH380A is reduced by 2.26%, lift coefficient of the trailing car by 19.67%. The variation of aerodynamic performance between the simplified train and the true train is mainly concentrated in the deformation region of the nose cone and tail cone. The optimization approach proposed in the present paper is simple yet efficient, and sheds lights on the constrained multi-objective engineering optimization design of aerodynamic shape of high-speed trains.展开更多
With the level of short-circuit current of power systems growing increasingly higher,optimal allocation of current limiters has received considerable attention in recent years,especially in China.This paper analyzes t...With the level of short-circuit current of power systems growing increasingly higher,optimal allocation of current limiters has received considerable attention in recent years,especially in China.This paper analyzes two kinds of common used current limiters based on the increment of bus impedance matrix and proposes a multi-objective current limiters configuration model considering the investment of limiters,the level of short-circuit current,as well as the transient stability of power system.An innovative search space reduction technique based on sensitivity factor is introduced to choose better candidate locations for current limiters so as to avoid the curse of dimensionality.The elitist non-dominated sorting genetic algorithm II is used to search the Pareto-optimal solutions of the proposed model.In order to further improve optimization efficiency,master-slave parallel modification of NSGA-II program structure is implemented.The satisfactory case study results demonstrate the feasibility of the proposed multi-objective method in power system current limiters allocation associated with cost,security and stability.展开更多
Pigeon-inspired optimization(PIO) is a new swarm intelligence optimization algorithm, which is inspired by the behavior of homing pigeons. A variant of pigeon-inspired optimization named multi-objective pigeon-inspire...Pigeon-inspired optimization(PIO) is a new swarm intelligence optimization algorithm, which is inspired by the behavior of homing pigeons. A variant of pigeon-inspired optimization named multi-objective pigeon-inspired optimization(MPIO) is proposed in this paper. It is also adopted to solve the multi-objective optimization problems in designing the parameters of brushless direct current motors, which has two objective variables, five design variables, and five constraint variables. Furthermore, comparative experimental results with the modified non-dominated sorting genetic algorithm are given to show the feasibility, validity and superiority of our proposed MIPO algorithm.展开更多
文摘Lot scheduling problem with idle time transfer between processes to minimize mean flow time is very important because to minimize mean flow time is to minimize work in process. But the problem is NP hard and no polynomial algorithm exists to guarantee optimal solution. Based the analysis the mathematical structure of the problem, the paper presents a new heuristic algorithm. Computer simulation shows that the proposed heuristic algorithm performs well in terms of both quality of solution and execution speed.
基金Project(ADLT 930-809R)supported by the Alabama Department of Transportation,USA
文摘To determine the onset and duration of contraflow evacuation, a multi-objective optimization(MOO) model is proposed to explicitly consider both the total system evacuation time and the operation cost. A solution algorithm that enhances the popular evolutionary algorithm NSGA-II is proposed to solve the model. The algorithm incorporates preliminary results as prior information and includes a meta-model as an alternative to evaluation by simulation. Numerical analysis of a case study suggests that the proposed formulation and solution algorithm are valid, and the enhanced NSGA-II outperforms the original algorithm in both convergence to the true Pareto-optimal set and solution diversity.
基金supported by a Stanford EDGE-STEM Fellowshipinitiated under NSF EAR-1254156 to Kate Maher and was also supported by the California Alliance Research Exchange NSF HRD-1306595 to C.Page Chamberlain
文摘Quantifying the functional relationships relating river discharge and weathering products places key constraints on the negative feedback between the silicate weathering and climate. In this study we analyze the concentration–discharge relationships of weathering products from global rivers using previously compiled time-series datasets for concentrations and discharge from global rivers. To analyze the nature of the covariation between specific discharge and concentrations, we use both a power law equation and a recently developed solute production equation. The solute production equation allows us to quantify weathering efficiency, or the resistance to dilution at high runoff, via the Damkohler coefficient. These results are also compared to those derived using average concentration–discharge pairs.Both the power law exponent and the Damkohler coefficient increase and asymptote as catchments exhibit increasingly chemostatic behavior, resulting in an inverse relationship between the two parameters. We also show that using thedistribution of average concentration–discharge pairs from global rivers, rather than fitting concentration–discharge relationships for each individual river, underestimates global median weathering efficiency by up to a factor of ~10. This study demonstrates the utility of long time-series sampling of global rivers to elucidate controlling processes needed to quantify patterns in global silicate weathering rates.
基金Project(2014BAG01B0403)supported by the High-Tech Research and Development Program of China
文摘In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed signal control at intersections, traffic assignment under traffic flow guidance, and dynamic characteristics of urban traffic management, a tri-level programming model is presented. To reflect the impact of intersection delay on traffic assignment, the lower level model is set as a modified user equilibrium model. The middle level model, which contains several definitional constraints for different phase modes, is built for the traffic signal control optimization. To solve the problem of tide lane management, the upper level model is built up based on nonlinear 0-1 integer programming. A heuristic iterative optimization algorithm(HIOA) is set up to solve the tri-level programming model. The lower level model is solved by method of successive averages(MSA), the middle level model is solved by non-dominated sorting genetic algorithm II(NSGA II), and the upper level model is solved by genetic algorithm(GA). A case study is raised to show the efficiency and applicability of the proposed modelling and computing method.
文摘We have developed a process for chemical purification of carbon nanotubes for solution-processable thin-film transistors (TFTs) having high mobility. Films of the purified carbon nanotubes fabricated by simple drop coating showed carrier mobilities as high as 164 cm2V-1s -1 normalized transconductances of 0.78 Sm-1 and on/off current ratios of 10^6. Such high performance requires the preparation of a suspension of micrometer-long and highly purified semiconducting single-walled carbon nanotubes (SWCNTs). Our purification process includes length and electronic-type selective trapping of SWCNTs using recycling gel filtration with a mixture of surfactants. The results provide an important milestone toward printed high-speed and large-area electronics with roll-to-roll and ink-jet device fabrication.
基金Project supported by the National Natural Science Foundation of China (Nos. 30872578 and 30753761)the Natural Science Founda-tion of Shanxi Province (No. SJ08C201)+1 种基金the Science and Technology Key Projects Foundation of Shanxi Province (No. 2008K13-04)the Science and Technology Plan Projects Foundation of Xi’an (No. SF08006-2), China
文摘Objective: In this paper we compared the two methods of cell sorting (magnetic cell sorting and flow cytometry sorting) for the isolation and function analysis of mouse CD4+ CD25+ regulatory T (Treg) cells, in order to inform further studies in Treg cell function. Methods: We separately used magnetic cell sorting and flow cytometry sorting to identify CD4+ CD25+ Treg cells. After magnetic cell separation, we further used flow cytometry to analyze the purity of CD4+ CD25+ Treg cells, trypan blue staining to detect cell viability, and propidium iodide (PI) staining to assess the cell viability. We detected the immune inhibition of CD4+ CD25+ Treg cells in the in vitro proliferation experiments. Results: The results showed that compared to flow cytometry sorting, magnetic cell sorting took more time and effort, but fewer live cells were obtained than with flow cytometry sorting. The CD4+ CD25+ Treg cells, however, obtained with both methods have similar immunosuppressive capacities. Conclusion: The result suggests that both methods can be used in isolating CD4+ CD25+ Treg cells, and one can select the best method according to specific needs and availability of the methodologies.
基金supported by the Major State Basic Research Development Program of China ("973" Program) (Grant No. 2011CB711100) National Key Technology R&D Program (Grant No. 2009BAQG12A03)
文摘As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also becomes the key force which affects the amenity and safety of the train. In the present paper, a simplified CRH380A high-speed train with three carriages is chosen as the model in order to optimize aerodynamic drag of the total train and aerodynamic lift of the trailing car. A constrained mul- ti-objective optimization design of the aerodynamic head shape of high-speed trains based on adaptive non-dominated sorting genetic algorithm is also developed combining local function three-dimensional parametric approach and central Latin hypercube sampling method with maximin criteria based on the iterative local search algorithm. The results show that local function parametric approach can be well applied to optimal design of complex three-dimensional aerodynamic shape, and the adaptive non-dominated sorting genetic algorithm can be more accurate and efficient to find the Pareto front. After optimization the aerodynamic drag of the simplified train with three carriages is reduced by 3.2%, and the lift coefficient of the trailing car by 8.24%, the volume of the streamlined head by 2.16%; the aerodynamic drag of the real prototype CRH380A is reduced by 2.26%, lift coefficient of the trailing car by 19.67%. The variation of aerodynamic performance between the simplified train and the true train is mainly concentrated in the deformation region of the nose cone and tail cone. The optimization approach proposed in the present paper is simple yet efficient, and sheds lights on the constrained multi-objective engineering optimization design of aerodynamic shape of high-speed trains.
文摘With the level of short-circuit current of power systems growing increasingly higher,optimal allocation of current limiters has received considerable attention in recent years,especially in China.This paper analyzes two kinds of common used current limiters based on the increment of bus impedance matrix and proposes a multi-objective current limiters configuration model considering the investment of limiters,the level of short-circuit current,as well as the transient stability of power system.An innovative search space reduction technique based on sensitivity factor is introduced to choose better candidate locations for current limiters so as to avoid the curse of dimensionality.The elitist non-dominated sorting genetic algorithm II is used to search the Pareto-optimal solutions of the proposed model.In order to further improve optimization efficiency,master-slave parallel modification of NSGA-II program structure is implemented.The satisfactory case study results demonstrate the feasibility of the proposed multi-objective method in power system current limiters allocation associated with cost,security and stability.
基金partially supported by the National Natural Science Foundation of China(Grant Nos.61425008,61333004 and 61273054)National Key Basic Research Program of China("973"Project)(Grant Nos.2014CB046401 and 2013CB035503)Top-Notch Young Talents Program of China,Aeronautical Foundation of China(Grant No.20135851042)
文摘Pigeon-inspired optimization(PIO) is a new swarm intelligence optimization algorithm, which is inspired by the behavior of homing pigeons. A variant of pigeon-inspired optimization named multi-objective pigeon-inspired optimization(MPIO) is proposed in this paper. It is also adopted to solve the multi-objective optimization problems in designing the parameters of brushless direct current motors, which has two objective variables, five design variables, and five constraint variables. Furthermore, comparative experimental results with the modified non-dominated sorting genetic algorithm are given to show the feasibility, validity and superiority of our proposed MIPO algorithm.