Based on the superposition principle of the nucleate boiling and convective heat transfer terms,a new correlation is developed for flow boiling heat transfer characteristics in helically coiled tubes.The effects of th...Based on the superposition principle of the nucleate boiling and convective heat transfer terms,a new correlation is developed for flow boiling heat transfer characteristics in helically coiled tubes.The effects of the geometric and system parameters on heat transfer characteristics in helically coiled tubes are investigated by collecting large amounts of experimental data and analyzing the heat transfer mechanisms. The existing correlations are divided into two categories,and they are calculated with the experimental data.The Dn factor is introduced to take into account the effect of a complex geometrical structure on flow boiling heat transfer.A new correlation is developed for predicting the flow boiling heat transfer coefficients in the helically coiled tubes,which is validated by the experimental data of R134a flow boiling heat transfer in them;and the average relative error and root mean square error of the new correlation are calculated.The results show that the new correlation agrees well with the experimental data,indicating that the new correlation can be used for predicting flow boiling heat transfer characteristics in the helically coiled tubes.展开更多
This paper presents the methodology of process driven analysis to eliminate the redundant information conducted from homogeneous procedures in management system. Process flow is emphasized and events triggered by pro...This paper presents the methodology of process driven analysis to eliminate the redundant information conducted from homogeneous procedures in management system. Process flow is emphasized and events triggered by process based states are described.展开更多
On the basis of PDM(product data management) definition and its connotation, the factors to ensure implementation success are analyzed. The definition phase, analysis phase, design phase, build and test phase, and pos...On the basis of PDM(product data management) definition and its connotation, the factors to ensure implementation success are analyzed. The definition phase, analysis phase, design phase, build and test phase, and post production phase during PDM implementation are described. The implementation is divided into ten processes, which consist of the above different phases. The relationships between phases and processes are illustrated. Finally, a workflow is proposed to guide the implementing at a fixed price.展开更多
A novel strip-coil-baffle structure used to enhance heat transfer and support the tube bundle for a tube-shell heat exchanger is proposed. The new structure can sleeve the tubes in bundle alternatively to create a vor...A novel strip-coil-baffle structure used to enhance heat transfer and support the tube bundle for a tube-shell heat exchanger is proposed. The new structure can sleeve the tubes in bundle alternatively to create a vortex flow in a heat exchanger. The numerical simulation on the flow and heat transfer characteristics for this new structure heat exchanger is conducted. The computational domain consists of two strip-coil sleeved tubes and two bare tubes oppositely placed at each comer of a square. The velocity and temperature fields in such strip-coil-baffled channel are simulated using FLUENT software. The effects of the strip-coil-baffles on heat transfer enhancement and flow resistance in relation to the Reynolds number are analyzed. The results show that this new structure bundle can enhance the heat transfer coefficient up to a range of 40% to 55% in comparison with a bare tube bundle; meanwhile, higher flow resistance is also accompanied. It is believe that the strip-coil- baffled heat exchanger should have promising applications in many industry fields.展开更多
This work was aimed at gaining understanding of the physical behaviours of the flow and temperature separation process in a vortex tube. To investigate the cold mass fraction’s effect on the temperature separation, t...This work was aimed at gaining understanding of the physical behaviours of the flow and temperature separation process in a vortex tube. To investigate the cold mass fraction’s effect on the temperature separation, the numerical calculation was carried out using an algebraic Reynolds stress model (ASM) and the standard k-ε model. The modelling of turbulence of com-pressible, complex flows used in the simulation is discussed. Emphasis is given to the derivation of the ASM for 2D axisymmet-rical flows, particularly to the model constants in the algebraic Reynolds stress equations. The TEFESS code, based on a staggered Finite Volume approach with the standard k-ε model and first-order numerical schemes, was used to carry out all the computations. The predicted results for strongly swirling turbulent compressible flow in a vortex tube suggested that the use of the ASM leads to better agreement between the numerical results and experimental data, while the k-ε model cannot capture the stabilizing effect of the swirl.展开更多
AIM: To investigate the symptom presentation and quality of life in obese Chinese patients with gastro- esophageal reflux disease (GERD). MKTHODS: Data from patients diagnosed with GERD according to the Montreal d...AIM: To investigate the symptom presentation and quality of life in obese Chinese patients with gastro- esophageal reflux disease (GERD). MKTHODS: Data from patients diagnosed with GERD according to the Montreal definition, were collected between January 2009 to March 2010. The enrolled patients were assigned to the normal [body mass in- dex (BMI) 〈 25 kg/m2], overweight (25-30 kg/m2), and obese (BMI 〉 30 kg/m2) groups. General demographic data, endoscopic findings, and quality of life of the three groups of patients were analyzed and compared.and 15 patients were classified in the normal, over- weight, and obese, respectively. There was significantly more erosive esophagitis (73.3% vs 64.3% vs 39.2%, P = 0.002), hiatal hernia (60% vs 33.9% vs 16.7%, P = 0.001), and males (73.3% vs 73.2% vs 32.4%, P = 0.001) in the obese cases. The severity and frequency of heartburn, not acid regurgitation, was positively cor- related with BMI, with a significant association in men, but not in women. Obese patients were prone to have low quality of life scores, with obese women having the lowest scores for mental health. CONCLUSION: In patients with GERD, obese men had the most severe endoscopic and clinical presenta- tion. Obese women had the poorest mental health.展开更多
Based on the energy equation of gas-liquid flow in pipeline,the explicit temperature drop formula for gas-liquid steady state calculation was derived.This formula took into consideration the Joule-Thomson effect,impac...Based on the energy equation of gas-liquid flow in pipeline,the explicit temperature drop formula for gas-liquid steady state calculation was derived.This formula took into consideration the Joule-Thomson effect,impact of terrain undulation and heat transfer with the surroundings along the line.Elimination of temperature iteration loop and integration of the explicit temperature equation,instead of enthalpy energy equation,into the conjugated hydraulic and thermal computation have been found to improve the efficiency of algorithm.Then,the inner wall temperature of gas-liquid flow was calculated by using explicit temperature equation and inner wall convective heat transfer coefficient of mixed flow which can be obtained by liquid convective heat transfer coefficient and gas convective heat transfer coefficient on the basis of liquid holdup.The temperature results of gas-liquid flow and inner wall in the case example presented both agree well with those in professional multiphase computational software OLGA.展开更多
This article gives a numerical report to two dimensional(2D)Darcy-Forchheimer flow of carbon-water nanofluid.Flow is instigated by exponential extending curved surface.Viscous liquid in permeable space is described by...This article gives a numerical report to two dimensional(2D)Darcy-Forchheimer flow of carbon-water nanofluid.Flow is instigated by exponential extending curved surface.Viscous liquid in permeable space is described by Darcy-Forchheimer.The subsequent arrangement of partial differential equations is changed into ordinary differential framework through proper transformations.Numerical arrangements of governing frameworks are set up by NDSolve procedure.Outcomes of different sundry parameters on temperature and velocity are examined.Skin friction and heat transfer rate are also shown and inspected.展开更多
AIM: To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD) METHODS: We conducted a cross-sectional study of consecutive patients underg...AIM: To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD) METHODS: We conducted a cross-sectional study of consecutive patients undergoing ambulatory 24-h dual-probe pH monitoring from July 2003 to December 2006. The association between body mass index (BMI) and parameters about gastroesophageal or gastropharyngeal reflux was examined in univariate and multivariate analyses.RESULTS: A total of 769 patients (307 men and 462 women; mean age 50.7 years) were finally enrolled. Most variables showing gastroesophageal reflux was higher in the obese patients than the patients with normal BMI. There was no difference in all the variables showing gastropharyngeal reflux according to the BMI. After adjustment for age, sex, alcohol intake and smoking, obese patients demonstrated an about 2-fold increase in risk of GERD compared with patients with normal BMI (OR, 1.9; 95 CI, 1.3-2.9), but overweight patients did not demonstrate increased risk of GERD (OR, 1.2; 95 CI, 0.8-1.7). Both obese patients and overweight patients did not demonstrated increased risk of GPRD compared with patients with normal BMI (OR, 1.1; 95 CI, 0.8-1.7; and OR, 0.9; 95 CI, 0.6-1.3, respectively).CONCLUSION: Obesity is not associated with GPRD reflux while it is associated with GERD.展开更多
A better understanding of two-phase flows with evaporation allows leading to an optimal design of evaporators. For that purpose, numerical simulations are very useful. In this paper, a numerical study has been carried...A better understanding of two-phase flows with evaporation allows leading to an optimal design of evaporators. For that purpose, numerical simulations are very useful. In this paper, a numerical study has been carried out in order to model and simulate the combination of a two-phase flow with evaporation in a vertical tube. The VOF (volume-of-fluid) multiphase flow method and a phase-change model for the mass transfer have been used. For an accurate modeling, the effect of axial conduction has been also taken into account using a conjugate heat transfer model. Since thermal oscillations are undesirable as they can lead to the failure of the tube, flow instabilities have also been analyzed, using FFT (fast Fourier transforms), in order to comprehend their behavior and influence. A control study of the flow instabilities in the tube is also presented. For that purpose tube inlet temperature has been varied using a gain control parameter.展开更多
A case of ideal fluid flow in a moving ending rigid constant diameter circular pipeline is investigated. A model of the pipeline was established based on distributed-parameter theory. The comparisons on a quotient mod...A case of ideal fluid flow in a moving ending rigid constant diameter circular pipeline is investigated. A model of the pipeline was established based on distributed-parameter theory. The comparisons on a quotient module of output and input pressure of the moving ending model and neglected ending moving model are made on the frequency response. It is revealed that the moving ending of pipeline influences largely the quotient amplitude of output and input pressure, and the peak value of frequency resonance increases with the increase of pipeline’s length.展开更多
The pressure drop of gas-liquid two-phase flow in microchannel is of fundamental importance in heat and mass transfer processes. In this work,the pressure drop of gas-liquid two-phase flow in horizontal rectangular cr...The pressure drop of gas-liquid two-phase flow in microchannel is of fundamental importance in heat and mass transfer processes. In this work,the pressure drop of gas-liquid two-phase flow in horizontal rectangular cross-section microchannels was measured by a pressure differential transducer system. Water,ethanol and n-propanol were used as liquid phase to study the effects of capillary number on pressure drop;air was used as the gas phase. Four microchannels with various dimensions of 100 μm× 200 μm,100 μm× 400 μm,100 μm× 800 μm and 100 μm× 2000 μm(depth × width) were used for determining the influence of configuration on the pressure drop. Experimental results showed that in micro-scale,the capillary number also affected the pressure drop remarkably,and in spite of only one-fold difference in aspect ratio,the variation of pressure drop reached up to near three times under the same experimental conditions. Taking the effects of aspect ratio and surface tension into account,a modi-fied correlation for Chisholm parameter C in the Chisholm model was proposed for predicting the frictional multi-plier,and the predicted values by the proposed correlation showed a satisfactory agreement with experimental data.展开更多
A good understanding of the detailed temperature distribution in the furnace plays an important role in the implementation of operation optimization and design improvement of ethylene pyrolyzer. Numerical simulation o...A good understanding of the detailed temperature distribution in the furnace plays an important role in the implementation of operation optimization and design improvement of ethylene pyrolyzer. Numerical simulation of the turbulent flow, combustion and heat transfer was carried out to investigate the temperature distribution in industrial furnace. Inhomogeneities of the flue-gas temperature distribution were observed in X, Y, and Z direction of the furnace from the simulated results. Along the height of the furnace, the average flue-gas temperature increased initially and decreased afterward, and reached its peak at the height of 5 m. The reactor tube skin temperature varied not only along the height of the furnace, but also around the circumference of the tube. The heat flux profiles from the furnace towards the reactor tubes followed the shape of the average flue-gas temperature profile. The heat flux of the inlet tubes was constantly higher than that of the outlet tubes at the same height in the furnace.展开更多
A new type of multi-tube column, in which a novel internal-structure is installed in the bed of random packing, has been invented. The internal-structure reduces the hydraulic radius of the column and adjusts the gas/...A new type of multi-tube column, in which a novel internal-structure is installed in the bed of random packing, has been invented. The internal-structure reduces the hydraulic radius of the column and adjusts the gas/liquid flow so that the liquid maldistribution is greatly abated. A mathematical model with boundary conditions based on close-open mechanism at the internal-structure was established to study the hydraulic behavior of such a column and experiments were carded out to verify the applicability of the model. Predictions from the model agreed well with experimental results. The optimal ratio of the hydraulic diameter of the new multi-tube column to the packing element diameter is found to be 17.5 to 23.3 by employing the optimization method of nonlinear programming. And this new type of multi-tube column opens a new way for random packing columns to be scaled up for industry.展开更多
Experiments and simulations on flow and heat transfer behavior of Therminol-55 liquid phase heat transfer fluid have been conducted in a ribbed tube with the outer diameter and inner diameter 25.0 and 20.0 mm,pitch an...Experiments and simulations on flow and heat transfer behavior of Therminol-55 liquid phase heat transfer fluid have been conducted in a ribbed tube with the outer diameter and inner diameter 25.0 and 20.0 mm,pitch and rib height of 4.5 and 1.0 mm.respectively.Experimental results show that the heat transfer and thermal performance of Therminol-55 liquid phase heat transfer fluid in the ribbed tube are considerably improved compared to those of the smooth tube.The Nusselt number increase with the increase of Reynolds number.The increase in heat transfer rate of the ribbed tube has a mean value of 2.24 times.Also,the pressure drop results reveal that the average friction factor of the ribbed tube is in a range of 2.4 and 2.8 times over the smooth tube.Numerical simulations of three-dimensional flow behavior of Therminol-55 liquid phase heat transfer fluid are carried out using three different turbulence models in the ribbed tube.The numerical results show that the heat transfer of ribbed tube is improved because vortices are generated behind ribs,which produce some disruptions to fluid flow and enhance heat transfer compared with smooth tube.The numerical results prove that the ribbed tube can improve heat transfer and fluid flow performances of Therminol liquid phase heat transfer fluid.展开更多
AIM: To assess the relationship between severity of gastroesophageal reflux disease and apnea-hypopnea index (AHI) as an indicator of the severity of obstructive sleep apnea. METHODS: Data of 57 patients with proven o...AIM: To assess the relationship between severity of gastroesophageal reflux disease and apnea-hypopnea index (AHI) as an indicator of the severity of obstructive sleep apnea. METHODS: Data of 57 patients with proven obstructive sleep apnea and gastroesophageal reflux disease were analyzed. Patients were divided into two groups according to severity of the sleep apnea: 'mild-moderate' (A)-AHI 5≥5-30, n=27, 'severe' (B)-AHI >30, n=30. All patients underwent apnea monitoring during the night, upper panendoscopy and were asked about typical reflux symptoms. RESULTS: All examined patients in both groups showed a significant overweight and there was a positive correlation between body mass index and the degree of sleep apnea (P = 0.0002). The occurence of erosive reflux disease was significantly higher in 'severe' group (P = 0.0001). Using a logistic regression analysis a positive correlation was found between the endoscopic severity of reflux disease and the AHI (P = 0.016). Forty-nine point five percent of the patients experienced the typical symptoms of reflux disease at least three times a week and there was no significant difference between the two groups. CONCLUSION: A positive correlation can be found between the severity of gastroesophageal reflux disease and obstructive sleep apnea.展开更多
AIM: To evaluate esophageal mucosal defense mechanisms at an epithelial level to establish if pantoprazole treatment can induce ultrastructural healing and improvement in the proliferation activity of the esophageal e...AIM: To evaluate esophageal mucosal defense mechanisms at an epithelial level to establish if pantoprazole treatment can induce ultrastructural healing and improvement in the proliferation activity of the esophageal epithelium in gastroesophageal reflux disease (GERD). METHODS: This was a single-blinded study for pHmonitoring, and histological, ultrastructural and MIB1 immunostaining evaluation. Fifty eight patients with GERD were enrolled and underwent 24 h pH-monitoring and endoscopy. Patients were treated for 12 and 24 mo with pantoprazole. Esophageal specimens were taken for histological and ultrastructural evaluation, before and after the treatment. RESULTS: With transmission electron microscopy, all patients with GERD showed ultrastructural signs of damage with dilation of intercellular spaces (DIS). After 3 mo of therapy the mean DIS values showed asignificant reduction and the mean MIB1-LI values of GERD showed an increase in cell proliferation. A further 3 mo of therapy significantly increased cell proliferation only in the erosive esophagitis (ERD) group. CONCLUSION: Three months of pantoprazole therapy induced ultrastructural healing of mucosal damage in 89% and 93% of ERD and non-erosion patients, respectively. Moreover, long-term pantoprazole treatment may be helpful in increasing the capability for esophageal cell proliferation in GERD, particularly in ERD patients.展开更多
This article describes numerical simulation of gas pipeline network operation using high-accuracy computational fluid dynamics (CFD) simulators of the modes of gas mixture transmission through long, multi-line pipelin...This article describes numerical simulation of gas pipeline network operation using high-accuracy computational fluid dynamics (CFD) simulators of the modes of gas mixture transmission through long, multi-line pipeline systems (CFD-simulator). The approach used in CFD-simulators for modeling gas mixture transmission through long, branched, multi-section pipelines is based on tailoring the full system of fluid dynamics equations to conditions of unsteady, non-isothermal processes of the gas mixture flow. Identification, in a CFD-simulator, of safe parameters for gas transmission through compressor stations amounts to finding the interior points of admissible sets described by systems of nonlinear algebraic equalities and inequalities. Such systems of equalities and inequalities comprise a formal statement of technological, design, operational and other constraints to which operation of the network equipment is subject. To illustrate the practicability of the method of numerical simulation of a gas transmission network, we compare computation results and gas flow parameters measured on-site at the gas transmission enter-prise.展开更多
In this study, we examined the expression of inducible nitric oxide s ynthase (iNOS) and vascular endothelial growth factor (VEGF) by immunohistoc hemi cal staining in 76 tissue sections collected from hepatocellula...In this study, we examined the expression of inducible nitric oxide s ynthase (iNOS) and vascular endothelial growth factor (VEGF) by immunohistoc hemi cal staining in 76 tissue sections collected from hepatocellular carcinoma (HCC) patients undergoing hepatectomy. Microvascular density (MVD) was determined by counting endothelial cells immunostained using anti-CD34 antibody. We performe d DNA-flow cytometric analyses to elucidate the impact of iNOS and VEGF expressi o n on the cell cycle of HCC. Most of the HCC cells that invaded stroma were mark edly immunostained by iNOS antibody. The iNOS stain intensity of the liver tissu e close to the tumor edge was stronger than that of HCC tissue, and the stronges t was the hepatocytes closer to the tumor tissue. However, iNOS expression in 10 normal hepatic samples was undetectable. VEGF positive expression ratio was 84. 8% in iNOS positive expression cases, and the ratio was 35.3% in negative cases. There was significant correlation (P=0.000) between iNOS and VEGF expressi on. Moreover, iNOS expression was significantly associated with bcl-2 and MVD, but w ithout p53 expression. DNA-flow cytometric analyses showed that combined expres s ion of iNOS and VEGF had significant impact on the cell cycle in HCC. PI (Proli ferating Index) and SPF (S-phase fraction) in the combined positive expression o f iNOS and VEGF group was significantly higher than that in the combined negativ e group. The present findings suggested that iNOS expression was significantly a ssociated with angiogenesis, bcl-2 and cell proliferation of HCC.展开更多
基金The National Natural Science Foundation of China(No.50776055,51076084)
文摘Based on the superposition principle of the nucleate boiling and convective heat transfer terms,a new correlation is developed for flow boiling heat transfer characteristics in helically coiled tubes.The effects of the geometric and system parameters on heat transfer characteristics in helically coiled tubes are investigated by collecting large amounts of experimental data and analyzing the heat transfer mechanisms. The existing correlations are divided into two categories,and they are calculated with the experimental data.The Dn factor is introduced to take into account the effect of a complex geometrical structure on flow boiling heat transfer.A new correlation is developed for predicting the flow boiling heat transfer coefficients in the helically coiled tubes,which is validated by the experimental data of R134a flow boiling heat transfer in them;and the average relative error and root mean square error of the new correlation are calculated.The results show that the new correlation agrees well with the experimental data,indicating that the new correlation can be used for predicting flow boiling heat transfer characteristics in the helically coiled tubes.
文摘This paper presents the methodology of process driven analysis to eliminate the redundant information conducted from homogeneous procedures in management system. Process flow is emphasized and events triggered by process based states are described.
文摘On the basis of PDM(product data management) definition and its connotation, the factors to ensure implementation success are analyzed. The definition phase, analysis phase, design phase, build and test phase, and post production phase during PDM implementation are described. The implementation is divided into ten processes, which consist of the above different phases. The relationships between phases and processes are illustrated. Finally, a workflow is proposed to guide the implementing at a fixed price.
基金The National Basic Research Program of China(973Program) (NoG2000026303)the National Natural Science Foun-dation of China (No50176008)
文摘A novel strip-coil-baffle structure used to enhance heat transfer and support the tube bundle for a tube-shell heat exchanger is proposed. The new structure can sleeve the tubes in bundle alternatively to create a vortex flow in a heat exchanger. The numerical simulation on the flow and heat transfer characteristics for this new structure heat exchanger is conducted. The computational domain consists of two strip-coil sleeved tubes and two bare tubes oppositely placed at each comer of a square. The velocity and temperature fields in such strip-coil-baffled channel are simulated using FLUENT software. The effects of the strip-coil-baffles on heat transfer enhancement and flow resistance in relation to the Reynolds number are analyzed. The results show that this new structure bundle can enhance the heat transfer coefficient up to a range of 40% to 55% in comparison with a bare tube bundle; meanwhile, higher flow resistance is also accompanied. It is believe that the strip-coil- baffled heat exchanger should have promising applications in many industry fields.
文摘This work was aimed at gaining understanding of the physical behaviours of the flow and temperature separation process in a vortex tube. To investigate the cold mass fraction’s effect on the temperature separation, the numerical calculation was carried out using an algebraic Reynolds stress model (ASM) and the standard k-ε model. The modelling of turbulence of com-pressible, complex flows used in the simulation is discussed. Emphasis is given to the derivation of the ASM for 2D axisymmet-rical flows, particularly to the model constants in the algebraic Reynolds stress equations. The TEFESS code, based on a staggered Finite Volume approach with the standard k-ε model and first-order numerical schemes, was used to carry out all the computations. The predicted results for strongly swirling turbulent compressible flow in a vortex tube suggested that the use of the ASM leads to better agreement between the numerical results and experimental data, while the k-ε model cannot capture the stabilizing effect of the swirl.
文摘AIM: To investigate the symptom presentation and quality of life in obese Chinese patients with gastro- esophageal reflux disease (GERD). MKTHODS: Data from patients diagnosed with GERD according to the Montreal definition, were collected between January 2009 to March 2010. The enrolled patients were assigned to the normal [body mass in- dex (BMI) 〈 25 kg/m2], overweight (25-30 kg/m2), and obese (BMI 〉 30 kg/m2) groups. General demographic data, endoscopic findings, and quality of life of the three groups of patients were analyzed and compared.and 15 patients were classified in the normal, over- weight, and obese, respectively. There was significantly more erosive esophagitis (73.3% vs 64.3% vs 39.2%, P = 0.002), hiatal hernia (60% vs 33.9% vs 16.7%, P = 0.001), and males (73.3% vs 73.2% vs 32.4%, P = 0.001) in the obese cases. The severity and frequency of heartburn, not acid regurgitation, was positively cor- related with BMI, with a significant association in men, but not in women. Obese patients were prone to have low quality of life scores, with obese women having the lowest scores for mental health. CONCLUSION: In patients with GERD, obese men had the most severe endoscopic and clinical presenta- tion. Obese women had the poorest mental health.
基金Project(2011ZX05000-026-004) supported by the National Science & Technology Specific Program of ChinaProject(2010D-5006-0604) supported by the China National Petroleum Corporation (CNPC) Innovation FoundationProject(51004167) supported by the National Natural Science Foundation of China
文摘Based on the energy equation of gas-liquid flow in pipeline,the explicit temperature drop formula for gas-liquid steady state calculation was derived.This formula took into consideration the Joule-Thomson effect,impact of terrain undulation and heat transfer with the surroundings along the line.Elimination of temperature iteration loop and integration of the explicit temperature equation,instead of enthalpy energy equation,into the conjugated hydraulic and thermal computation have been found to improve the efficiency of algorithm.Then,the inner wall temperature of gas-liquid flow was calculated by using explicit temperature equation and inner wall convective heat transfer coefficient of mixed flow which can be obtained by liquid convective heat transfer coefficient and gas convective heat transfer coefficient on the basis of liquid holdup.The temperature results of gas-liquid flow and inner wall in the case example presented both agree well with those in professional multiphase computational software OLGA.
文摘This article gives a numerical report to two dimensional(2D)Darcy-Forchheimer flow of carbon-water nanofluid.Flow is instigated by exponential extending curved surface.Viscous liquid in permeable space is described by Darcy-Forchheimer.The subsequent arrangement of partial differential equations is changed into ordinary differential framework through proper transformations.Numerical arrangements of governing frameworks are set up by NDSolve procedure.Outcomes of different sundry parameters on temperature and velocity are examined.Skin friction and heat transfer rate are also shown and inspected.
文摘AIM: To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD) METHODS: We conducted a cross-sectional study of consecutive patients undergoing ambulatory 24-h dual-probe pH monitoring from July 2003 to December 2006. The association between body mass index (BMI) and parameters about gastroesophageal or gastropharyngeal reflux was examined in univariate and multivariate analyses.RESULTS: A total of 769 patients (307 men and 462 women; mean age 50.7 years) were finally enrolled. Most variables showing gastroesophageal reflux was higher in the obese patients than the patients with normal BMI. There was no difference in all the variables showing gastropharyngeal reflux according to the BMI. After adjustment for age, sex, alcohol intake and smoking, obese patients demonstrated an about 2-fold increase in risk of GERD compared with patients with normal BMI (OR, 1.9; 95 CI, 1.3-2.9), but overweight patients did not demonstrate increased risk of GERD (OR, 1.2; 95 CI, 0.8-1.7). Both obese patients and overweight patients did not demonstrated increased risk of GPRD compared with patients with normal BMI (OR, 1.1; 95 CI, 0.8-1.7; and OR, 0.9; 95 CI, 0.6-1.3, respectively).CONCLUSION: Obesity is not associated with GPRD reflux while it is associated with GERD.
文摘A better understanding of two-phase flows with evaporation allows leading to an optimal design of evaporators. For that purpose, numerical simulations are very useful. In this paper, a numerical study has been carried out in order to model and simulate the combination of a two-phase flow with evaporation in a vertical tube. The VOF (volume-of-fluid) multiphase flow method and a phase-change model for the mass transfer have been used. For an accurate modeling, the effect of axial conduction has been also taken into account using a conjugate heat transfer model. Since thermal oscillations are undesirable as they can lead to the failure of the tube, flow instabilities have also been analyzed, using FFT (fast Fourier transforms), in order to comprehend their behavior and influence. A control study of the flow instabilities in the tube is also presented. For that purpose tube inlet temperature has been varied using a gain control parameter.
文摘A case of ideal fluid flow in a moving ending rigid constant diameter circular pipeline is investigated. A model of the pipeline was established based on distributed-parameter theory. The comparisons on a quotient module of output and input pressure of the moving ending model and neglected ending moving model are made on the frequency response. It is revealed that the moving ending of pipeline influences largely the quotient amplitude of output and input pressure, and the peak value of frequency resonance increases with the increase of pipeline’s length.
基金Supported by the National Natural Science Foundation of China (20876107) the Opening Project of State Key Laboratory of Chemical Engineering (SKL-ChE-08B06)
文摘The pressure drop of gas-liquid two-phase flow in microchannel is of fundamental importance in heat and mass transfer processes. In this work,the pressure drop of gas-liquid two-phase flow in horizontal rectangular cross-section microchannels was measured by a pressure differential transducer system. Water,ethanol and n-propanol were used as liquid phase to study the effects of capillary number on pressure drop;air was used as the gas phase. Four microchannels with various dimensions of 100 μm× 200 μm,100 μm× 400 μm,100 μm× 800 μm and 100 μm× 2000 μm(depth × width) were used for determining the influence of configuration on the pressure drop. Experimental results showed that in micro-scale,the capillary number also affected the pressure drop remarkably,and in spite of only one-fold difference in aspect ratio,the variation of pressure drop reached up to near three times under the same experimental conditions. Taking the effects of aspect ratio and surface tension into account,a modi-fied correlation for Chisholm parameter C in the Chisholm model was proposed for predicting the frictional multi-plier,and the predicted values by the proposed correlation showed a satisfactory agreement with experimental data.
文摘A good understanding of the detailed temperature distribution in the furnace plays an important role in the implementation of operation optimization and design improvement of ethylene pyrolyzer. Numerical simulation of the turbulent flow, combustion and heat transfer was carried out to investigate the temperature distribution in industrial furnace. Inhomogeneities of the flue-gas temperature distribution were observed in X, Y, and Z direction of the furnace from the simulated results. Along the height of the furnace, the average flue-gas temperature increased initially and decreased afterward, and reached its peak at the height of 5 m. The reactor tube skin temperature varied not only along the height of the furnace, but also around the circumference of the tube. The heat flux profiles from the furnace towards the reactor tubes followed the shape of the average flue-gas temperature profile. The heat flux of the inlet tubes was constantly higher than that of the outlet tubes at the same height in the furnace.
文摘A new type of multi-tube column, in which a novel internal-structure is installed in the bed of random packing, has been invented. The internal-structure reduces the hydraulic radius of the column and adjusts the gas/liquid flow so that the liquid maldistribution is greatly abated. A mathematical model with boundary conditions based on close-open mechanism at the internal-structure was established to study the hydraulic behavior of such a column and experiments were carded out to verify the applicability of the model. Predictions from the model agreed well with experimental results. The optimal ratio of the hydraulic diameter of the new multi-tube column to the packing element diameter is found to be 17.5 to 23.3 by employing the optimization method of nonlinear programming. And this new type of multi-tube column opens a new way for random packing columns to be scaled up for industry.
基金Supported by the National Natural Science Foundation of China(11472093 and21276056)
文摘Experiments and simulations on flow and heat transfer behavior of Therminol-55 liquid phase heat transfer fluid have been conducted in a ribbed tube with the outer diameter and inner diameter 25.0 and 20.0 mm,pitch and rib height of 4.5 and 1.0 mm.respectively.Experimental results show that the heat transfer and thermal performance of Therminol-55 liquid phase heat transfer fluid in the ribbed tube are considerably improved compared to those of the smooth tube.The Nusselt number increase with the increase of Reynolds number.The increase in heat transfer rate of the ribbed tube has a mean value of 2.24 times.Also,the pressure drop results reveal that the average friction factor of the ribbed tube is in a range of 2.4 and 2.8 times over the smooth tube.Numerical simulations of three-dimensional flow behavior of Therminol-55 liquid phase heat transfer fluid are carried out using three different turbulence models in the ribbed tube.The numerical results show that the heat transfer of ribbed tube is improved because vortices are generated behind ribs,which produce some disruptions to fluid flow and enhance heat transfer compared with smooth tube.The numerical results prove that the ribbed tube can improve heat transfer and fluid flow performances of Therminol liquid phase heat transfer fluid.
文摘AIM: To assess the relationship between severity of gastroesophageal reflux disease and apnea-hypopnea index (AHI) as an indicator of the severity of obstructive sleep apnea. METHODS: Data of 57 patients with proven obstructive sleep apnea and gastroesophageal reflux disease were analyzed. Patients were divided into two groups according to severity of the sleep apnea: 'mild-moderate' (A)-AHI 5≥5-30, n=27, 'severe' (B)-AHI >30, n=30. All patients underwent apnea monitoring during the night, upper panendoscopy and were asked about typical reflux symptoms. RESULTS: All examined patients in both groups showed a significant overweight and there was a positive correlation between body mass index and the degree of sleep apnea (P = 0.0002). The occurence of erosive reflux disease was significantly higher in 'severe' group (P = 0.0001). Using a logistic regression analysis a positive correlation was found between the endoscopic severity of reflux disease and the AHI (P = 0.016). Forty-nine point five percent of the patients experienced the typical symptoms of reflux disease at least three times a week and there was no significant difference between the two groups. CONCLUSION: A positive correlation can be found between the severity of gastroesophageal reflux disease and obstructive sleep apnea.
基金Supported by A Grant from MURST ex 60% to GDF and CC and a grant from Nycomed Italy
文摘AIM: To evaluate esophageal mucosal defense mechanisms at an epithelial level to establish if pantoprazole treatment can induce ultrastructural healing and improvement in the proliferation activity of the esophageal epithelium in gastroesophageal reflux disease (GERD). METHODS: This was a single-blinded study for pHmonitoring, and histological, ultrastructural and MIB1 immunostaining evaluation. Fifty eight patients with GERD were enrolled and underwent 24 h pH-monitoring and endoscopy. Patients were treated for 12 and 24 mo with pantoprazole. Esophageal specimens were taken for histological and ultrastructural evaluation, before and after the treatment. RESULTS: With transmission electron microscopy, all patients with GERD showed ultrastructural signs of damage with dilation of intercellular spaces (DIS). After 3 mo of therapy the mean DIS values showed asignificant reduction and the mean MIB1-LI values of GERD showed an increase in cell proliferation. A further 3 mo of therapy significantly increased cell proliferation only in the erosive esophagitis (ERD) group. CONCLUSION: Three months of pantoprazole therapy induced ultrastructural healing of mucosal damage in 89% and 93% of ERD and non-erosion patients, respectively. Moreover, long-term pantoprazole treatment may be helpful in increasing the capability for esophageal cell proliferation in GERD, particularly in ERD patients.
文摘This article describes numerical simulation of gas pipeline network operation using high-accuracy computational fluid dynamics (CFD) simulators of the modes of gas mixture transmission through long, multi-line pipeline systems (CFD-simulator). The approach used in CFD-simulators for modeling gas mixture transmission through long, branched, multi-section pipelines is based on tailoring the full system of fluid dynamics equations to conditions of unsteady, non-isothermal processes of the gas mixture flow. Identification, in a CFD-simulator, of safe parameters for gas transmission through compressor stations amounts to finding the interior points of admissible sets described by systems of nonlinear algebraic equalities and inequalities. Such systems of equalities and inequalities comprise a formal statement of technological, design, operational and other constraints to which operation of the network equipment is subject. To illustrate the practicability of the method of numerical simulation of a gas transmission network, we compare computation results and gas flow parameters measured on-site at the gas transmission enter-prise.
文摘In this study, we examined the expression of inducible nitric oxide s ynthase (iNOS) and vascular endothelial growth factor (VEGF) by immunohistoc hemi cal staining in 76 tissue sections collected from hepatocellular carcinoma (HCC) patients undergoing hepatectomy. Microvascular density (MVD) was determined by counting endothelial cells immunostained using anti-CD34 antibody. We performe d DNA-flow cytometric analyses to elucidate the impact of iNOS and VEGF expressi o n on the cell cycle of HCC. Most of the HCC cells that invaded stroma were mark edly immunostained by iNOS antibody. The iNOS stain intensity of the liver tissu e close to the tumor edge was stronger than that of HCC tissue, and the stronges t was the hepatocytes closer to the tumor tissue. However, iNOS expression in 10 normal hepatic samples was undetectable. VEGF positive expression ratio was 84. 8% in iNOS positive expression cases, and the ratio was 35.3% in negative cases. There was significant correlation (P=0.000) between iNOS and VEGF expressi on. Moreover, iNOS expression was significantly associated with bcl-2 and MVD, but w ithout p53 expression. DNA-flow cytometric analyses showed that combined expres s ion of iNOS and VEGF had significant impact on the cell cycle in HCC. PI (Proli ferating Index) and SPF (S-phase fraction) in the combined positive expression o f iNOS and VEGF group was significantly higher than that in the combined negativ e group. The present findings suggested that iNOS expression was significantly a ssociated with angiogenesis, bcl-2 and cell proliferation of HCC.