A simple, rapid and sensitive flow injection chemiluminescence （FI-CL） method has been developed for the determination of meloxicam. The method is based on the CL-emitting reaction between meloxicam and potassium pe...A simple, rapid and sensitive flow injection chemiluminescence （FI-CL） method has been developed for the determination of meloxicam. The method is based on the CL-emitting reaction between meloxicam and potassium permanganate in a hydrochloric acid medium, enhanced by formaldehyde （HCHO）. Under optimum conditions, calibration curve over the range of 1.0-20.0μg/mL was obtained. The proposed method was successfully applied to the determination of meloxicam in capsules with no evi- dence of interference from common excipients. The detection limit of this method was 25.6 ng/mL. The relative standard deviation was 2.1% for 10.0 μg/mL meloxicam. The sample throughput was found to be 120 samples/h.展开更多
AIM: To value whether omeprazole could induce the healing of DIS and regression of symptoms in patients with DGER. METHODS: We enrolled 15 symptomatic patients with a pathological esophageal 24-h pH-metry and bilimetr...AIM: To value whether omeprazole could induce the healing of DIS and regression of symptoms in patients with DGER. METHODS: We enrolled 15 symptomatic patients with a pathological esophageal 24-h pH-metry and bilimetry. Patients underwent endoscopy and biopsies were taken from the distal esophagus. Specimens were analyzed at histology and transmission electron microscopy (TEM). Patients were treated with omeprazole 40 mg/d for 3 mo and then endoscopy with biopsies was repeated. Patients with persistent heartburn and/or with an incomplete recovery of DIS were treated for 3 more months and endoscopy with biopsies was performed. RESULTS: Nine patients had a non-erosive reflux disease at endoscopy (NERD) while 6 had erosive esophagitis (ERD). At histology, of the 6 patients with erosive esophagitis, 5 had mild esophagitis and 1 moderate esophagitis. No patients with NERD showed histological signs of esophagitis. After 3 mo of therapy, 13/15 patients (86.7%,P<0.01) showed a complete recovery of DIS and disappearance of heartburn. Of the 2 patients treated for 3 more months, complete recovery of DIS and heartburn were achieved in one. CONCLUSION: Three or 6 mo of omeprazole therapy led to a complete regression of the ultrastructural esophageal damage in 86.7% and in 93% of patients with DGER, NERD and ERD respectively. The ultrastructural recovery of the epithelium was accompanied by regression of heartburn in all cases.展开更多
In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between...In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between,across,and within health communities will improve one's healthcare experience across their lifespan.Patient health information,i.e.the personal health record,should be shareable between healthcare providers;such as private practice physicians,home health agencies,hospitals and nursing care facilities.Most of the U.S.hospitals now have electronic health records,however,with a lack of standards for structuring health information and unified communication protocols to share health information across providers,only a small percentage of U.S.hospitals engage in computerized HIE.In order to understand barriers and facilitators in the U.S.of HIE adoption,we reviewed the published research literature between 2010 and 2015.Our search yielded 664 articles from Medline,PsychInfo,Global health,InSpec,Scopus and Business Source Complete databases.Thirty-nine articles met our inclusion criteria.This article presents the compiled organizational and end user barriers and facilitators along with suggested methods to achieve continuity of care through HIE.展开更多
Extranodal natural killer （NK）IT-cell lymphoma, nasal type （ENKTCL） is a rarely kind of non-Hodgkin lymphoma （NHL）. It is much more frequent in Asian and Latin American countries than other part of the world. It...Extranodal natural killer （NK）IT-cell lymphoma, nasal type （ENKTCL） is a rarely kind of non-Hodgkin lymphoma （NHL）. It is much more frequent in Asian and Latin American countries than other part of the world. It typically affects nasal cavity. In China, one of its endemically places, ENKTCL accounts for 74%-96% of nasal NHL. Patients with ENKTCL usually show a highly aggressive clinical course, and its etiology is unclear. However, it is already proved that ENKTCL is associated with Epstein-Barr virus （EBV） infection, regardless patients＇, ethnicity and areas. Some studies show that the risk will increase among several occupations, such as farmer, who are frequently exposure to pesticides and chemical solvent and risk can be cut down if taking some protective measures.展开更多
Neo-merchantalism is the use of national currency in international trade among countries to increase global trade. This is called as open currency in the study. Neo-merchantalism also includes open trade to facilitate...Neo-merchantalism is the use of national currency in international trade among countries to increase global trade. This is called as open currency in the study. Neo-merchantalism also includes open trade to facilitate trade among countries. Thirdly, neo-merchantalism covers International Monetary Fund （IMF）. Because IMF regulates and controls money flow among countries in international trade, neo-merchantalism could be presented as follows： neo-merchantalism = open trade ＋ open currency ＋ IMF. Open trade and open currency exist in merchantalism theory. But today, there is also IMF control. Therefore, neo-merchantalism = merchantalism ＋ IMF. Globalism started in 1990 in global markets. It increased the amount of global trade from 13 trillion dollars to 60 trillion dollars. Therefore, each country has 6%-7% economic growth in global markets in the 2000s. It is expected that neo-merchantalism theory doubles global trade up to 100 trillion dollars. Because each country uses its money to do intemational trade, IMF＇s restrictions are important in currency flow, as countries may overprint their money to do more trade that increases inflation rate in global economies. For example, emission of United States （US） dollars increased 50% after 2008 crises in American economy. Therefore, the Federal Reserve aims to stop quantitative enlargement policy in order to impede inflation in American economy. In neo-merchantalism, IMF can restrict money print and currency flow according to country＇s gross domestic product （GDP）, because quantity theory in economy requires that a country can issue its national currency according to its national GDP.展开更多
This essay focuses on the interaction between the publication of female travel writing about the South of Italy in non-feminist 19th century British periodicals, and the circulation of a transgressive model of feminin...This essay focuses on the interaction between the publication of female travel writing about the South of Italy in non-feminist 19th century British periodicals, and the circulation of a transgressive model of femininity centred on the concepts of mobility, vitality and visibility. The choice of Southern Italy, an anti-tourist destination that since the era of the Grand Tour had been considered dangerous for men, let alone for women, magnifies female heroic attitudes and contaminates female conventional domestic purity enhancing the concept of an unfixed female identity. The publication of a travelogue, a mostly non-fictional genre, on an innovative and reactive medium, was a manifest act of transgression with respect to fixed social order, which gave visibility and credibility to a different model of femininity, an anti-Angel icon. A new form of narration displays adventurous women able to cross the private sphere and to write/publish authentic accounts of their transitional experience in a public, male-dominated sphere.展开更多
AIM: To clarify whether there is any difference in the symptom relief in patients with reflux esophagitis following the administration of four Proton pump inhibitors (PPIs). METHODS: Two hundred and seventy-four patie...AIM: To clarify whether there is any difference in the symptom relief in patients with reflux esophagitis following the administration of four Proton pump inhibitors (PPIs). METHODS: Two hundred and seventy-four patients with erosive reflux esophagitis were randomized to receive 8 wk of 20 mg omeprazole (n = 68), 30 mg of lansoprazole (n = 69), 40 mg of pantoprazole (n = 69), 40 mg of esomeprazole (n = 68) once a day in the morning. Daily changes in heartburn and acid reflux symptoms in the first 7 d of administration were assessed using a six-point scale (0: none; 1: mild; 2: mild-moderate; 3: moderate; 4: moderate-severe; 5: severe). RESULTS: The mean heartburn score in patients treated with esomeprazole more rapidly decreased than those receiving other PPI. Complete resolution of heartburn was also more rapid in patients treated with esomeprazole for 5 d compared with omeprazole (P = 0.0018, P = 0.0098, P = 0.0027, P = 0.0137, P = 0.0069, respectively), lansoprazole (P = 0.0020, P = 0.0046, P = 0.0037, P = 0.0016, P = 0.0076, respectively), and pantoprazole (P = 0.0006, P = 0.0005, P = 0.0009, P = 0.0031, P = 0.0119, respectively). There were no significant differences between the four groups in the rate of endoscopic healing of reflux esophagitis at week 8. CONCLUSION: Esomeprazole may be more effective than omeprazole, lansoprazole, and pantoprazole for the rapid relief of heartburn symptoms and acid reflux symptoms in patients with reflux esophagitis.展开更多
文摘A simple, rapid and sensitive flow injection chemiluminescence （FI-CL） method has been developed for the determination of meloxicam. The method is based on the CL-emitting reaction between meloxicam and potassium permanganate in a hydrochloric acid medium, enhanced by formaldehyde （HCHO）. Under optimum conditions, calibration curve over the range of 1.0-20.0μg/mL was obtained. The proposed method was successfully applied to the determination of meloxicam in capsules with no evi- dence of interference from common excipients. The detection limit of this method was 25.6 ng/mL. The relative standard deviation was 2.1% for 10.0 μg/mL meloxicam. The sample throughput was found to be 120 samples/h.
文摘AIM: To value whether omeprazole could induce the healing of DIS and regression of symptoms in patients with DGER. METHODS: We enrolled 15 symptomatic patients with a pathological esophageal 24-h pH-metry and bilimetry. Patients underwent endoscopy and biopsies were taken from the distal esophagus. Specimens were analyzed at histology and transmission electron microscopy (TEM). Patients were treated with omeprazole 40 mg/d for 3 mo and then endoscopy with biopsies was repeated. Patients with persistent heartburn and/or with an incomplete recovery of DIS were treated for 3 more months and endoscopy with biopsies was performed. RESULTS: Nine patients had a non-erosive reflux disease at endoscopy (NERD) while 6 had erosive esophagitis (ERD). At histology, of the 6 patients with erosive esophagitis, 5 had mild esophagitis and 1 moderate esophagitis. No patients with NERD showed histological signs of esophagitis. After 3 mo of therapy, 13/15 patients (86.7%,P<0.01) showed a complete recovery of DIS and disappearance of heartburn. Of the 2 patients treated for 3 more months, complete recovery of DIS and heartburn were achieved in one. CONCLUSION: Three or 6 mo of omeprazole therapy led to a complete regression of the ultrastructural esophageal damage in 86.7% and in 93% of patients with DGER, NERD and ERD respectively. The ultrastructural recovery of the epithelium was accompanied by regression of heartburn in all cases.
文摘In order to improve patient care in the United States there,the government made a mandate called HIE(Health Information Exchange).This order was created from the belief that sharing digital health in-formation between,across,and within health communities will improve one's healthcare experience across their lifespan.Patient health information,i.e.the personal health record,should be shareable between healthcare providers;such as private practice physicians,home health agencies,hospitals and nursing care facilities.Most of the U.S.hospitals now have electronic health records,however,with a lack of standards for structuring health information and unified communication protocols to share health information across providers,only a small percentage of U.S.hospitals engage in computerized HIE.In order to understand barriers and facilitators in the U.S.of HIE adoption,we reviewed the published research literature between 2010 and 2015.Our search yielded 664 articles from Medline,PsychInfo,Global health,InSpec,Scopus and Business Source Complete databases.Thirty-nine articles met our inclusion criteria.This article presents the compiled organizational and end user barriers and facilitators along with suggested methods to achieve continuity of care through HIE.
文摘Extranodal natural killer （NK）IT-cell lymphoma, nasal type （ENKTCL） is a rarely kind of non-Hodgkin lymphoma （NHL）. It is much more frequent in Asian and Latin American countries than other part of the world. It typically affects nasal cavity. In China, one of its endemically places, ENKTCL accounts for 74%-96% of nasal NHL. Patients with ENKTCL usually show a highly aggressive clinical course, and its etiology is unclear. However, it is already proved that ENKTCL is associated with Epstein-Barr virus （EBV） infection, regardless patients＇, ethnicity and areas. Some studies show that the risk will increase among several occupations, such as farmer, who are frequently exposure to pesticides and chemical solvent and risk can be cut down if taking some protective measures.
文摘Neo-merchantalism is the use of national currency in international trade among countries to increase global trade. This is called as open currency in the study. Neo-merchantalism also includes open trade to facilitate trade among countries. Thirdly, neo-merchantalism covers International Monetary Fund （IMF）. Because IMF regulates and controls money flow among countries in international trade, neo-merchantalism could be presented as follows： neo-merchantalism = open trade ＋ open currency ＋ IMF. Open trade and open currency exist in merchantalism theory. But today, there is also IMF control. Therefore, neo-merchantalism = merchantalism ＋ IMF. Globalism started in 1990 in global markets. It increased the amount of global trade from 13 trillion dollars to 60 trillion dollars. Therefore, each country has 6%-7% economic growth in global markets in the 2000s. It is expected that neo-merchantalism theory doubles global trade up to 100 trillion dollars. Because each country uses its money to do intemational trade, IMF＇s restrictions are important in currency flow, as countries may overprint their money to do more trade that increases inflation rate in global economies. For example, emission of United States （US） dollars increased 50% after 2008 crises in American economy. Therefore, the Federal Reserve aims to stop quantitative enlargement policy in order to impede inflation in American economy. In neo-merchantalism, IMF can restrict money print and currency flow according to country＇s gross domestic product （GDP）, because quantity theory in economy requires that a country can issue its national currency according to its national GDP.
文摘This essay focuses on the interaction between the publication of female travel writing about the South of Italy in non-feminist 19th century British periodicals, and the circulation of a transgressive model of femininity centred on the concepts of mobility, vitality and visibility. The choice of Southern Italy, an anti-tourist destination that since the era of the Grand Tour had been considered dangerous for men, let alone for women, magnifies female heroic attitudes and contaminates female conventional domestic purity enhancing the concept of an unfixed female identity. The publication of a travelogue, a mostly non-fictional genre, on an innovative and reactive medium, was a manifest act of transgression with respect to fixed social order, which gave visibility and credibility to a different model of femininity, an anti-Angel icon. A new form of narration displays adventurous women able to cross the private sphere and to write/publish authentic accounts of their transitional experience in a public, male-dominated sphere.
文摘AIM: To clarify whether there is any difference in the symptom relief in patients with reflux esophagitis following the administration of four Proton pump inhibitors (PPIs). METHODS: Two hundred and seventy-four patients with erosive reflux esophagitis were randomized to receive 8 wk of 20 mg omeprazole (n = 68), 30 mg of lansoprazole (n = 69), 40 mg of pantoprazole (n = 69), 40 mg of esomeprazole (n = 68) once a day in the morning. Daily changes in heartburn and acid reflux symptoms in the first 7 d of administration were assessed using a six-point scale (0: none; 1: mild; 2: mild-moderate; 3: moderate; 4: moderate-severe; 5: severe). RESULTS: The mean heartburn score in patients treated with esomeprazole more rapidly decreased than those receiving other PPI. Complete resolution of heartburn was also more rapid in patients treated with esomeprazole for 5 d compared with omeprazole (P = 0.0018, P = 0.0098, P = 0.0027, P = 0.0137, P = 0.0069, respectively), lansoprazole (P = 0.0020, P = 0.0046, P = 0.0037, P = 0.0016, P = 0.0076, respectively), and pantoprazole (P = 0.0006, P = 0.0005, P = 0.0009, P = 0.0031, P = 0.0119, respectively). There were no significant differences between the four groups in the rate of endoscopic healing of reflux esophagitis at week 8. CONCLUSION: Esomeprazole may be more effective than omeprazole, lansoprazole, and pantoprazole for the rapid relief of heartburn symptoms and acid reflux symptoms in patients with reflux esophagitis.
