The complete nucleotide sequence of the mumps virus SP, which was isolated in China, was determined. As with other mumps viruses, its genome was 15 384 nucleotides (nts) in length and encoded seven proteins. The full-...The complete nucleotide sequence of the mumps virus SP, which was isolated in China, was determined. As with other mumps viruses, its genome was 15 384 nucleotides (nts) in length and encoded seven proteins. The full-length nucleotide sequence of the SP isolate differed from other strains by 4% –6.8% at the nucleotide sequence level. Due to variations of amino acids over the full genome (including the HN and N genes), this isolate exhibited significant variations in the antigenic sites. This report is the first to describe the full-length genome of a genotype F strain and provide an overview of the diversity of genetic characteristics of a circulating mumps virus.展开更多
Objective： To compare the clinical efficacy difference between comprehensive ying needling therapy and intramuscular injection with ribavirin for mumps.Methods： One hundred patients with mumps were randomly divided ...Objective： To compare the clinical efficacy difference between comprehensive ying needling therapy and intramuscular injection with ribavirin for mumps.Methods： One hundred patients with mumps were randomly divided into comprehensive ying needling therapy group（group A, 52 cases） and western medicine group（group B, 48 cases）, then 8 cases were eliminated and drop out from group A and 4 cases were eliminated and drop out from group B respectively. actual inclusion 44 cases in group A 44 cases in group B. Point bloodletting was performed at parotid gland（腮腺Sāixiàn） and Threeshang acupoints of the patients in group A for once every other day, treatment for 7 days was considered as 1 course of treatment, and 2 courses were needed. Intramuscular injection with ribavirin was given to the patients in group B for twice a day, treatment for 7 days was considered as 1 course, and 2 courses were needed. The parotid gland swelling score, fever score, orifice parotid duct swelling score, score of difficulty in opening mouth and the clinical efficacy of the patients in the two groups were compared before and after treatment.Results： The cured and markedly effective rate in group A was 90.9%（40/44）, which was superior to 68.2%in group B（30/44）（P〈0.05）. The symptom scores were all improved significantly in the two groups after treatment（all P〈0.05）, and the improvement in group A was superior to that in group B（all P〈0.05）.Conclusion： The curative effect of comprehensive ying needling therapy for treatment of mumps was superior to that of conventional western medicine therapy.展开更多
基金Public Benefit Grant of Ministry of Health, China (200802035)Natural Science Foundation of Yunnan province (2008CD153)
文摘The complete nucleotide sequence of the mumps virus SP, which was isolated in China, was determined. As with other mumps viruses, its genome was 15 384 nucleotides (nts) in length and encoded seven proteins. The full-length nucleotide sequence of the SP isolate differed from other strains by 4% –6.8% at the nucleotide sequence level. Due to variations of amino acids over the full genome (including the HN and N genes), this isolate exhibited significant variations in the antigenic sites. This report is the first to describe the full-length genome of a genotype F strain and provide an overview of the diversity of genetic characteristics of a circulating mumps virus.
基金Supported by Science-Technology Support Plan Project of Jiangxi Province:20151BBG70194~~
文摘Objective： To compare the clinical efficacy difference between comprehensive ying needling therapy and intramuscular injection with ribavirin for mumps.Methods： One hundred patients with mumps were randomly divided into comprehensive ying needling therapy group（group A, 52 cases） and western medicine group（group B, 48 cases）, then 8 cases were eliminated and drop out from group A and 4 cases were eliminated and drop out from group B respectively. actual inclusion 44 cases in group A 44 cases in group B. Point bloodletting was performed at parotid gland（腮腺Sāixiàn） and Threeshang acupoints of the patients in group A for once every other day, treatment for 7 days was considered as 1 course of treatment, and 2 courses were needed. Intramuscular injection with ribavirin was given to the patients in group B for twice a day, treatment for 7 days was considered as 1 course, and 2 courses were needed. The parotid gland swelling score, fever score, orifice parotid duct swelling score, score of difficulty in opening mouth and the clinical efficacy of the patients in the two groups were compared before and after treatment.Results： The cured and markedly effective rate in group A was 90.9%（40/44）, which was superior to 68.2%in group B（30/44）（P〈0.05）. The symptom scores were all improved significantly in the two groups after treatment（all P〈0.05）, and the improvement in group A was superior to that in group B（all P〈0.05）.Conclusion： The curative effect of comprehensive ying needling therapy for treatment of mumps was superior to that of conventional western medicine therapy.
