AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) ...AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation.展开更多
To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By us...To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By using the continuity equation and Tait state equation as well as Riabouchinsky closure model, an“inverse problem”solution is presented for the supercavitating flow. According to the impenetrable condition on the surface of supercavity, a new iterative method for the supercavity shape is designed to deal with the effect of compressibility on the supercavity shape, pressure drag coefficient and density field. By this method, the very low cavitation number can be computed. The calculated results agree well with the experimental data and empirical formula. At the subsonic condition, the fluid compressibility will make supercavity length and radius increase. The supercavity expands, but remains spheroid. The effect on the first 1/3 part of supercavity is not obvious. The drag coefficient of projectile increases as the cavitation number or Mach number increases. With Mach number increasing, the compressibility is more and more significant. The compressibility must be considered as far as the accurate calculation of supercavitating flow is concerned.展开更多
Fine particles are difficult to fluidize due to strong interparticle attraction.An attempt has been made to study the bed expansion of silica gel(dp=25μm) powder in presence of an acoustic field.A 135 mm diameter flu...Fine particles are difficult to fluidize due to strong interparticle attraction.An attempt has been made to study the bed expansion of silica gel(dp=25μm) powder in presence of an acoustic field.A 135 mm diameter fluidized bed activated by an acoustic field with sound intensity up to 145 dB and frequency from 90 Hz to 170 Hz was studied.The effects of sound pressure level,sound frequency and particle loading on the bed expansion were investigated.Experimental results showed that,bed expansion was good in presence of acoustic field of particular frequency.In addition,it was observed that in presence of acoustic field the bed collapses slowly.展开更多
Community Radio is a medium which the different threads mingle together brings different social threads together and weaves a vibrant fabric where all without compromising their original composition. Freedom of speech...Community Radio is a medium which the different threads mingle together brings different social threads together and weaves a vibrant fabric where all without compromising their original composition. Freedom of speech and expression is the cornerstone of this medium. In India, Community Radio started its journey in 2004, with the purpose of bringing different sections of the society together so that they can share their experiences, fears, and ambition. Social intervention has been one of the primary agenda Community Radio. Through various awareness-raising programs, it aims to bring positive social change in the lives of people residing around its transmission zone. It also aims to include different sub-sections of its community who are often excluded from the mainstream media.展开更多
The present paper, in spite of its quite scandalous title, is just a serious reflection, from the inside, on a certain part of the poetry of a contemporary Romanian poet (the author of the paper himself), in the lin...The present paper, in spite of its quite scandalous title, is just a serious reflection, from the inside, on a certain part of the poetry of a contemporary Romanian poet (the author of the paper himself), in the line of a tradition starting with Poe's Philosophy of Composition (1846), passing through the avant-garde and ending, for the moment, in Andy Warhol's self-promotion. The analysis from the inside and the honest reflection of the interplay between poetry, music, and contemporary popular culture might lead to a better understanding of the poetry made at the end of the 20th century--beginning of the 21 st century. The corpus analyzed is a series of poems written between 1994 and the present day, under the generic title of ditty, published in several books (between which a bilingual pamphlet, Ditties/Cfntecelce), 1998), and the paper speaks about their genesis, their poetics, and hopes to help the process of their interpretation, as well as to bring a new interpretation of the poetry/music relationship展开更多
Gas-particle two-phase flow is a very important consideration in designing various machines. Although a great deal of theoretical, experimental, and numerical research has been carried out, particle motion in a supers...Gas-particle two-phase flow is a very important consideration in designing various machines. Although a great deal of theoretical, experimental, and numerical research has been carried out, particle motion in a supersonic flow has not been sufficiently clarified. Hence, in order to clarify the interactions between flow and particles, the authors consider the characteristics of particle motion, especially at high temperatures. In the present study, the flow of a gas with a diluted particle load is to be simulated in a conventional converging-diverging supersonic nozzle. The turbulent gas flow in the nozzle is computed with the finite difference and RANS (raynolds averaged navier-stokes simulation) methods. The particle motion is simulated in a Lagrangian manner. In addition, taking into account the light particle loading, a weak coupling method is used. Through this investigation, it is shown that the particle velocity increases monotonically from the nozzle throat to the outlet. And it is shown that particles can be accelerated to higher velocities in helium than in nitrogen, and smaller particles tend to attain higher speed and lower static temperature.展开更多
The near casing flow fields inside the rotor passage of a 1.5 stage axial compressor with different blade-loading levels and tip gap sizes were measured by using stereoscopic particle image velocimetry(SPIV). Based on...The near casing flow fields inside the rotor passage of a 1.5 stage axial compressor with different blade-loading levels and tip gap sizes were measured by using stereoscopic particle image velocimetry(SPIV). Based on a carefully defined blockage extracting method, the variations of blockage parameter inside the blade passage were analyzed. It was found that the variation of blockage parameter appeared as a non-monotonic behavior inside the blade passage in most cases. This non-monotonic behavior became much more remarkable as the blade loading increases or mass flow rate decreases.The variations of the blockage parameter inside the blade passage had close relation to the evolutionary procedures of the tip leakage vortex(TLV). The destabilization of the TLV caused a rapid increasing of the blockage parameter. After the TLV lost the features of a concentrated streamwise vortex,the blockage parameter usually got a peak value. And then, because of the intense turbulent mixing between the TLV low momentum flow and its surrounding flows, the flow deficit inside the TLV recovered.展开更多
The supersonic mixing layer flow,consisting of a relatively cold,slow diluted hydrogen stream and a hot,faster air stream,is numerically simulated with detailed transport properties and chemical reaction mechanisms.Th...The supersonic mixing layer flow,consisting of a relatively cold,slow diluted hydrogen stream and a hot,faster air stream,is numerically simulated with detailed transport properties and chemical reaction mechanisms.The evolution of the combustion process in the supersonic reacting mixing layer is observed and unsteady phenomena of ignition,flame propagation and extinction are successfully captured.The ignition usually takes place at the air stream side of braid regions between two vortexes due to much higher temperature of premixed gases.After ignition,the flame propagates towards two vortexes respectively located on the upstream and downstream of the ignition position.The apparent flame speed is 1569.97 m/s,which is much higher than the laminar flame speed,resulting from the effects of expansion,turbulence,vortex stretching and consecutive ignition.After the flame arrives at the former vortex,the flame propagates along the outer region of the vortex in two branches.Then the upper flame branch close to fuel streamside distinguishes gradually due to too fuel-riched premixed mixtures in the front of the flame and the strong cooling effect of the adjacent cool fuel flow,while the lower flame branch continues to propagate in the vortex.展开更多
This paper reports the direct numerical simulation (DNS) for hypersonic turbulent boundary layer over a flat-plate at Ma∞ =8 with the ratio of wall-to-freestream temperature equal to 1.9, which indicates an extremely...This paper reports the direct numerical simulation (DNS) for hypersonic turbulent boundary layer over a flat-plate at Ma∞ =8 with the ratio of wall-to-freestream temperature equal to 1.9, which indicates an extremely cold wall condition. It is primarily used to assess the wall temperature effects on the mean velocity profile, Walz equation, turbulent intensity, strong Reynolds analogy (SRA), and compressibility. The present high Mach number with cold wall condition induces strong compressibility effects. As a result, the Morkovin's hypothesis is not fully valid and so the classical SRA is also not fully consistent. However, some modified SRA is still valid at the far-wall region. It is also verified that the semi-local wall coordinate y* is better than conventional y+ in analysis of statistics features in turbulent boundary layer (TBL) in hypersonic flow.展开更多
Increasing demand for downsizing of engines to improve CO2 emissions has resulted in renewed efforts to improve the efficiency and expend the stable operating range of the centrifugal compressors used in petro-chemica...Increasing demand for downsizing of engines to improve CO2 emissions has resulted in renewed efforts to improve the efficiency and expend the stable operating range of the centrifugal compressors used in petro-chemical equipment and turbochargers. The losses in these compressors are dominated by tip clearance flow. In this paper, the tip clearance flow in the subsonic impeller is numerically investigated. The nature of the tip clearance in inducer, axial to radial bend and exducer are studied in detail at design and off-design conditions by examining the detailed flow field through the clearance and the interaction of the clearance flow with the shear effect with the endwalls. The correlation between blade loading and span wise geometry and clearance flow at different locations are presented.展开更多
基金Supported by The Department of Anesthesiology and Perioperative Medicine,Tufts Medical Center,Boston,United States
文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation.
基金Foundation item: Supported by the National Natural Science Foundation of China (Grant No. 51309230), and China Postdoctoral Science Foundation (Nos. 2014T70992 and 2013 M542531)We would like to thank Dr. Tao Miao for closely following our work and making several useful suggestions.
文摘To deal with the effect of compressible fluids on the supercavitating flow over the subsonic disk cavitator of a projectile, a finite volume method is formulated based on the ideal compressible potential theory. By using the continuity equation and Tait state equation as well as Riabouchinsky closure model, an“inverse problem”solution is presented for the supercavitating flow. According to the impenetrable condition on the surface of supercavity, a new iterative method for the supercavity shape is designed to deal with the effect of compressibility on the supercavity shape, pressure drag coefficient and density field. By this method, the very low cavitation number can be computed. The calculated results agree well with the experimental data and empirical formula. At the subsonic condition, the fluid compressibility will make supercavity length and radius increase. The supercavity expands, but remains spheroid. The effect on the first 1/3 part of supercavity is not obvious. The drag coefficient of projectile increases as the cavitation number or Mach number increases. With Mach number increasing, the compressibility is more and more significant. The compressibility must be considered as far as the accurate calculation of supercavitating flow is concerned.
文摘Fine particles are difficult to fluidize due to strong interparticle attraction.An attempt has been made to study the bed expansion of silica gel(dp=25μm) powder in presence of an acoustic field.A 135 mm diameter fluidized bed activated by an acoustic field with sound intensity up to 145 dB and frequency from 90 Hz to 170 Hz was studied.The effects of sound pressure level,sound frequency and particle loading on the bed expansion were investigated.Experimental results showed that,bed expansion was good in presence of acoustic field of particular frequency.In addition,it was observed that in presence of acoustic field the bed collapses slowly.
文摘Community Radio is a medium which the different threads mingle together brings different social threads together and weaves a vibrant fabric where all without compromising their original composition. Freedom of speech and expression is the cornerstone of this medium. In India, Community Radio started its journey in 2004, with the purpose of bringing different sections of the society together so that they can share their experiences, fears, and ambition. Social intervention has been one of the primary agenda Community Radio. Through various awareness-raising programs, it aims to bring positive social change in the lives of people residing around its transmission zone. It also aims to include different sub-sections of its community who are often excluded from the mainstream media.
文摘The present paper, in spite of its quite scandalous title, is just a serious reflection, from the inside, on a certain part of the poetry of a contemporary Romanian poet (the author of the paper himself), in the line of a tradition starting with Poe's Philosophy of Composition (1846), passing through the avant-garde and ending, for the moment, in Andy Warhol's self-promotion. The analysis from the inside and the honest reflection of the interplay between poetry, music, and contemporary popular culture might lead to a better understanding of the poetry made at the end of the 20th century--beginning of the 21 st century. The corpus analyzed is a series of poems written between 1994 and the present day, under the generic title of ditty, published in several books (between which a bilingual pamphlet, Ditties/Cfntecelce), 1998), and the paper speaks about their genesis, their poetics, and hopes to help the process of their interpretation, as well as to bring a new interpretation of the poetry/music relationship
文摘Gas-particle two-phase flow is a very important consideration in designing various machines. Although a great deal of theoretical, experimental, and numerical research has been carried out, particle motion in a supersonic flow has not been sufficiently clarified. Hence, in order to clarify the interactions between flow and particles, the authors consider the characteristics of particle motion, especially at high temperatures. In the present study, the flow of a gas with a diluted particle load is to be simulated in a conventional converging-diverging supersonic nozzle. The turbulent gas flow in the nozzle is computed with the finite difference and RANS (raynolds averaged navier-stokes simulation) methods. The particle motion is simulated in a Lagrangian manner. In addition, taking into account the light particle loading, a weak coupling method is used. Through this investigation, it is shown that the particle velocity increases monotonically from the nozzle throat to the outlet. And it is shown that particles can be accelerated to higher velocities in helium than in nitrogen, and smaller particles tend to attain higher speed and lower static temperature.
基金funded by the National Natural Science Foundation of China,Grant No.51006007,51136003 and 50976009
文摘The near casing flow fields inside the rotor passage of a 1.5 stage axial compressor with different blade-loading levels and tip gap sizes were measured by using stereoscopic particle image velocimetry(SPIV). Based on a carefully defined blockage extracting method, the variations of blockage parameter inside the blade passage were analyzed. It was found that the variation of blockage parameter appeared as a non-monotonic behavior inside the blade passage in most cases. This non-monotonic behavior became much more remarkable as the blade loading increases or mass flow rate decreases.The variations of the blockage parameter inside the blade passage had close relation to the evolutionary procedures of the tip leakage vortex(TLV). The destabilization of the TLV caused a rapid increasing of the blockage parameter. After the TLV lost the features of a concentrated streamwise vortex,the blockage parameter usually got a peak value. And then, because of the intense turbulent mixing between the TLV low momentum flow and its surrounding flows, the flow deficit inside the TLV recovered.
文摘The supersonic mixing layer flow,consisting of a relatively cold,slow diluted hydrogen stream and a hot,faster air stream,is numerically simulated with detailed transport properties and chemical reaction mechanisms.The evolution of the combustion process in the supersonic reacting mixing layer is observed and unsteady phenomena of ignition,flame propagation and extinction are successfully captured.The ignition usually takes place at the air stream side of braid regions between two vortexes due to much higher temperature of premixed gases.After ignition,the flame propagates towards two vortexes respectively located on the upstream and downstream of the ignition position.The apparent flame speed is 1569.97 m/s,which is much higher than the laminar flame speed,resulting from the effects of expansion,turbulence,vortex stretching and consecutive ignition.After the flame arrives at the former vortex,the flame propagates along the outer region of the vortex in two branches.Then the upper flame branch close to fuel streamside distinguishes gradually due to too fuel-riched premixed mixtures in the front of the flame and the strong cooling effect of the adjacent cool fuel flow,while the lower flame branch continues to propagate in the vortex.
基金supported by the National Nature Science Foundation of China(Grant No. 11072248)the National Basic Research Program(Grant No. 2009CB724100)+1 种基金the National High-tech R&D Program(No.2012AA01A304)the CAS Information Project(INFO-115-B01)
文摘This paper reports the direct numerical simulation (DNS) for hypersonic turbulent boundary layer over a flat-plate at Ma∞ =8 with the ratio of wall-to-freestream temperature equal to 1.9, which indicates an extremely cold wall condition. It is primarily used to assess the wall temperature effects on the mean velocity profile, Walz equation, turbulent intensity, strong Reynolds analogy (SRA), and compressibility. The present high Mach number with cold wall condition induces strong compressibility effects. As a result, the Morkovin's hypothesis is not fully valid and so the classical SRA is also not fully consistent. However, some modified SRA is still valid at the far-wall region. It is also verified that the semi-local wall coordinate y* is better than conventional y+ in analysis of statistics features in turbulent boundary layer (TBL) in hypersonic flow.
基金supported by the National Natural Science Foundation of China (Grant No. 51276125)the National Basic Research Program of China ("973" Project) (Grant No. 2012CB720101)
文摘Increasing demand for downsizing of engines to improve CO2 emissions has resulted in renewed efforts to improve the efficiency and expend the stable operating range of the centrifugal compressors used in petro-chemical equipment and turbochargers. The losses in these compressors are dominated by tip clearance flow. In this paper, the tip clearance flow in the subsonic impeller is numerically investigated. The nature of the tip clearance in inducer, axial to radial bend and exducer are studied in detail at design and off-design conditions by examining the detailed flow field through the clearance and the interaction of the clearance flow with the shear effect with the endwalls. The correlation between blade loading and span wise geometry and clearance flow at different locations are presented.