Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three ...Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three types of crushed rock samples. Three methods of confidence interval in describing permeability coefficients are presented: the secure interval, the calculated interval and the systemic interval. The lower bound of the secure interval can be applied to water-inrush and the upper bound can solve the problem of connectivity. For the calculated interval, as the axial pressure increases, the length of confidence interval is shortened and the upper and lower bounds are reduced. For the systemic interval, the length of its confidence interval, as well as the upper and lower bounds, clearly vary under low axial pressure but are fairly similar under high axial pressure. These three methods provide useful information and references for analyzing the permeability coefficient of over-broken rock.展开更多
In view of the importance of the hotel segment for the tourism and for the economy of countries such as Portugal, the objective of this study was to measure the level of orientation for the market of the largest hotel...In view of the importance of the hotel segment for the tourism and for the economy of countries such as Portugal, the objective of this study was to measure the level of orientation for the market of the largest hotel groups of Portugal. This investigation initially emphasized the importance of the marketing for the organizations, mainly the orientation for the market. After a brief explanation on the hotel segment in Portugal, an empirical study was presented, of quantitative, exploratory and traversal character, performed with the largest groups of 20 hotels of Portugal, using as an instrument of collection data, the traditional Markor scale (market orientation) adapted to the hotel sector. After analyzing the data, it was found in the investigated organizations that a good capacity to generate market information and response to the market, which formed two of the three constructs of Markor scale. However the results obtained with the construct of the dissemination of market information were below the expectations. It was possible to conclude that marketing professionals of the large hotel groups in Portugal are well oriented to the market, something not shared by other investigated departments of the hotels. So the current challenge for the main networks of hotels in Portugal is to improve the internal dissemination of information that marketing professionals gathered at the market.展开更多
String kernels are popular tools for analyzing protein sequence data and they have been successfully applied to many computational biology problems. The traditional string kernels assume that different substrings are ...String kernels are popular tools for analyzing protein sequence data and they have been successfully applied to many computational biology problems. The traditional string kernels assume that different substrings are independent. However, substrings can be highly correlated due to their substructure relationship or common physico-chemical properties. This paper proposes two kinds of weighted spectrum kernels: The correlation spectrum kernel and the AA spectrum kernel. We evMuate their performances by predicting glycan-binding proteins of 12 glycans. The results show that the correlation spectrum kernel and the AA spectrum kernel perform significantly better than the spectrum kernel for nearly all the 12 glycans. By comparing the predictive power of AA spectrum kernels constructed by different physico-chemical properties, the authors can also identify the physico- chemical properties which contributes the most to the glycan-protein binding. The results indicate that physico-chemical properties of amino acids in proteins play an important role in the mechanism of glycamprotein binding.展开更多
基金Financial support for this work, provided by the National Natural Science Foundation of China (Nos. 50774083 and 41074040)the Program for New Century Excellent Talents in University (No. NCET-07-0803)the National Key Basic Research Program (No. 2009CB219605)
文摘Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three types of crushed rock samples. Three methods of confidence interval in describing permeability coefficients are presented: the secure interval, the calculated interval and the systemic interval. The lower bound of the secure interval can be applied to water-inrush and the upper bound can solve the problem of connectivity. For the calculated interval, as the axial pressure increases, the length of confidence interval is shortened and the upper and lower bounds are reduced. For the systemic interval, the length of its confidence interval, as well as the upper and lower bounds, clearly vary under low axial pressure but are fairly similar under high axial pressure. These three methods provide useful information and references for analyzing the permeability coefficient of over-broken rock.
文摘In view of the importance of the hotel segment for the tourism and for the economy of countries such as Portugal, the objective of this study was to measure the level of orientation for the market of the largest hotel groups of Portugal. This investigation initially emphasized the importance of the marketing for the organizations, mainly the orientation for the market. After a brief explanation on the hotel segment in Portugal, an empirical study was presented, of quantitative, exploratory and traversal character, performed with the largest groups of 20 hotels of Portugal, using as an instrument of collection data, the traditional Markor scale (market orientation) adapted to the hotel sector. After analyzing the data, it was found in the investigated organizations that a good capacity to generate market information and response to the market, which formed two of the three constructs of Markor scale. However the results obtained with the construct of the dissemination of market information were below the expectations. It was possible to conclude that marketing professionals of the large hotel groups in Portugal are well oriented to the market, something not shared by other investigated departments of the hotels. So the current challenge for the main networks of hotels in Portugal is to improve the internal dissemination of information that marketing professionals gathered at the market.
基金supported in part by Research Grants Council of Hong Kong under Grant No.17301214HKU CERG Grants+2 种基金Hung Hing Ying Physical Research Grantthe Research Funds of Renmin University of Chinathe National Natural Science Foundation of China under Grant Nos.11271144,11101382,11471256,and S201201009985
文摘String kernels are popular tools for analyzing protein sequence data and they have been successfully applied to many computational biology problems. The traditional string kernels assume that different substrings are independent. However, substrings can be highly correlated due to their substructure relationship or common physico-chemical properties. This paper proposes two kinds of weighted spectrum kernels: The correlation spectrum kernel and the AA spectrum kernel. We evMuate their performances by predicting glycan-binding proteins of 12 glycans. The results show that the correlation spectrum kernel and the AA spectrum kernel perform significantly better than the spectrum kernel for nearly all the 12 glycans. By comparing the predictive power of AA spectrum kernels constructed by different physico-chemical properties, the authors can also identify the physico- chemical properties which contributes the most to the glycan-protein binding. The results indicate that physico-chemical properties of amino acids in proteins play an important role in the mechanism of glycamprotein binding.