A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardwa...A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardware and software of this apparatus were designed,and detecting algorithms based on conservation of energy method (COEM) were presented. According to the law of conservation of energy that the energy derived by human body equals energy consumed by metabolism,and the relationship between convection,evaporation,radiation and the BGL was established. The sensor module was designed. 20 healthy volunteers were involved in the clinical experiment. The BGL measured by an automatic biochemical analyzer (ABA) was set as the reference. Regression analysis was performed to compare the conservation of energy method with the biochemical method,using the 20 data points with blood glucose concentrations ranging from 680 to 1 100 mg/L. Reproducibility was measured for healthy fasting volunteers. The results show that the means of BGL detected by NBGMA and ANA are very close to each other,and the difference of standard deviation (SD) is 24.7 mg/L. The correlative coefficient is 0.807. The coefficient of variation (CV) is 4% at 921.6 mg/L. The resultant regression is evaluated by the Clarke error grid analysis (EGA) and all data points are included in the clinically acceptable regions (region A:100%,region B:0%). Accordingly,it is feasible to measure BGL with COEM.展开更多
Wind measurements derived from QuikSCAT data were compared with those measured by anemometer on Yongxing Island in the South China Sea (SCS) for the period from April 2008 to November 2009. The comparison confirms tha...Wind measurements derived from QuikSCAT data were compared with those measured by anemometer on Yongxing Island in the South China Sea (SCS) for the period from April 2008 to November 2009. The comparison confirms that QuikSCAT estimates of wind speed and direction are generally accurate, except for the extremes of high wind speeds (>13.8m/s) and very low wind speeds (<1.5m/s) where direction is poorly predicted. In-situ observations show that the summer monsoon in the northern SCS starts between May 6 and June 1. From March 13, 2010 to August 31, 2010, comparisons of sea surface temperature (SST) and rainfall from AMSR-E with data from a buoy located at Xisha Islands, as well as wind measurements derived from ASCAT and observations from an automatic weather station show that QuikSCAT, ASCAT and AMSR-E data are good enough for research. It is feasible to optimize the usage of remote-sensing data if validated with in-situ measurements. Remarkable changes were observed in wind, barometric pressure, humidity, outgoing longwave radiation (OLR), air temperature, rainfall and SST during the monsoon onset. The eastward shift of western Pacific subtropical high and the southward movement of continental cold front preceded the monsoon onset in SCS. The starting dates of SCS summer monsoon indicated that the southwest monsoon starts in the Indochinese Peninsula and forms an eastward zonal belt, and then the belt bifurcates in the SCS, with one part moving northeastward into the tropical western North Pacific, and another southward into western Kalimantan. This largely determined the pattern of the SCS summer monsoon. Wavelet analysis of zonal wind and OLR at Xisha showed that intra-seasonal variability played an important role in the summer. This work improves the accuracy of the amplitude of intra-seasonal and synoptic variation obtained from remote-sensed data.展开更多
Many kinds of high temperature superconductor （HTS） power machines such as HTS cable, HTS fault current limitcr and HTS magnet are cooled by liquid nitrogen. The level of liquid nitrogen should be monitored and cont...Many kinds of high temperature superconductor （HTS） power machines such as HTS cable, HTS fault current limitcr and HTS magnet are cooled by liquid nitrogen. The level of liquid nitrogen should be monitored and controlled to ensure the thermal stability and the dielectric strength as well. To measure the level, capacitance method and differential pressure method are usually used. However, each method has installation difficulties and measurement errors for unsteady state operation with varying system pressure. A new liquid level meter using a 2G HTS conductor is described, which has similar structure with the liquid helium level meter with NbTi filament. The level meter is fabricated with a parallel connected heater, which helps the separation of the superconducting region and normal region, considering the critical temperature, large heat capacity of conductor and cooling characteristics. The level of liquid nitrogen can be obtained from the measured voltage signal along the 2G HTS conductor. Design, fabrication and test results of the new liquid nitrogen level meter are presented.展开更多
AIM： To study the morphology and ontogeny of dendritic cells of Peyer＇s patches in rats at different development periods. METHODS： The morphometric and flow cytometric analyses were performed to detect all the para...AIM： To study the morphology and ontogeny of dendritic cells of Peyer＇s patches in rats at different development periods. METHODS： The morphometric and flow cytometric analyses were performed to detect all the parameters of villous-crypts axis and the number of OX62＋DC, OX62＋CD4＋SIRP＋DC, and OX62＋CD4-SIRP-DC in the small intestine in different groups of rats. The relationship between the parameters of villous-axis and the number of DC and DC subtype were analyzed. RESULTS： All morphometric parameters changed significantly with the development of pups in the different age groups （F = 10.751, 12.374, 16.527, 5.291, 3.486; P = 0.000, 0.000, 0.000, 0.001, 0.015）. Villous height levels were unstable and increased from 115.24μm to 140.43 μm as early as 3 wk postpartum. Villous area increased significantly between 5 and 7 wk postpartum, peeked up to 13817.60 tam2 at 7 wk postpartum. Villous height and crypt depth ratios were relatively stable and increased significantly from 2.80 ＋ 1.01 to 4.54 =1= 1.56, 9-11 wk postpartum. The expression of OX62＋DC increased from 33.30%±5.80% to 80%± 17.30%, 3-11 wk postpartum （F =5.536, P = 0.0013）. OX62＋CD4＋SIRP＋DC subset levels detected in single-cell suspensions of rat total Peyer＇s patch dendritic cells （PP-DCs） increased significantly from 30.73% ± 5.16% to 35.50% ± 4.08%, 5-7 wk postpartum and from 34.20% ±1.35% to 43.60% ± 2.07% 9-11 wk postpartum （F = 7.216, P = 0.005）. CONCLUSION： This study confirms the agerelated changes in villous-crypt axis differentiation in the small intestine. Simultaneously, there are also development and maturation in rat PP-DCs phenotypic expression. Furthermore, the morphological changes of intestinal mucosa and the development of immune cells （especially DC） peaked at 9-11 wk postpartum, indicating that the intestinal mucosae reached a relatively mature state at 11 wk postpartum.展开更多
Attitude adjustment is a key link in the installation process of underwater facilities in deep water.To solve this problem,an omnidirectional spirit level for deep water was developed.The sealing principle of the spir...Attitude adjustment is a key link in the installation process of underwater facilities in deep water.To solve this problem,an omnidirectional spirit level for deep water was developed.The sealing principle of the spirit level and the principle of deep-water pressure resistance are analyzed,and the threaded connection strength is checked.The mechanical simulation verifies that the spirit level can withstand the pressure of 2000 m water depth,and the water pressure test is carried out for 30 min in a 20 MPa hyperbaric chamber.After the experiment is completed,the appearance of the spirit level is intact and there is no leakage.The experiment results show that the deep-water omnidirectional spirit level can be used in the deep sea within 2000 m.展开更多
基金Project(07JJ6133) supported by the Natural Science Foundation of Hunan Province, China
文摘A new non-invasive blood glucose measuring apparatus (NBGMA) made up of MSP430F149 SCM (single chip micyoco) was developed,which can measure blood glucose level (BGL) frequently,conveniently and painlessly. The hardware and software of this apparatus were designed,and detecting algorithms based on conservation of energy method (COEM) were presented. According to the law of conservation of energy that the energy derived by human body equals energy consumed by metabolism,and the relationship between convection,evaporation,radiation and the BGL was established. The sensor module was designed. 20 healthy volunteers were involved in the clinical experiment. The BGL measured by an automatic biochemical analyzer (ABA) was set as the reference. Regression analysis was performed to compare the conservation of energy method with the biochemical method,using the 20 data points with blood glucose concentrations ranging from 680 to 1 100 mg/L. Reproducibility was measured for healthy fasting volunteers. The results show that the means of BGL detected by NBGMA and ANA are very close to each other,and the difference of standard deviation (SD) is 24.7 mg/L. The correlative coefficient is 0.807. The coefficient of variation (CV) is 4% at 921.6 mg/L. The resultant regression is evaluated by the Clarke error grid analysis (EGA) and all data points are included in the clinically acceptable regions (region A:100%,region B:0%). Accordingly,it is feasible to measure BGL with COEM.
基金Supported by the National Basic Research Program of China (973 Program)(No. 2011CB403504)the Knowledge Innovation Program of Chinese Academy of Sciences (Nos. KZCX2-YW-Q11-02, KZCX2-YW-Y202)the National Natural Science Foundation of China (Nos. 40830851, 41006011)
文摘Wind measurements derived from QuikSCAT data were compared with those measured by anemometer on Yongxing Island in the South China Sea (SCS) for the period from April 2008 to November 2009. The comparison confirms that QuikSCAT estimates of wind speed and direction are generally accurate, except for the extremes of high wind speeds (>13.8m/s) and very low wind speeds (<1.5m/s) where direction is poorly predicted. In-situ observations show that the summer monsoon in the northern SCS starts between May 6 and June 1. From March 13, 2010 to August 31, 2010, comparisons of sea surface temperature (SST) and rainfall from AMSR-E with data from a buoy located at Xisha Islands, as well as wind measurements derived from ASCAT and observations from an automatic weather station show that QuikSCAT, ASCAT and AMSR-E data are good enough for research. It is feasible to optimize the usage of remote-sensing data if validated with in-situ measurements. Remarkable changes were observed in wind, barometric pressure, humidity, outgoing longwave radiation (OLR), air temperature, rainfall and SST during the monsoon onset. The eastward shift of western Pacific subtropical high and the southward movement of continental cold front preceded the monsoon onset in SCS. The starting dates of SCS summer monsoon indicated that the southwest monsoon starts in the Indochinese Peninsula and forms an eastward zonal belt, and then the belt bifurcates in the SCS, with one part moving northeastward into the tropical western North Pacific, and another southward into western Kalimantan. This largely determined the pattern of the SCS summer monsoon. Wavelet analysis of zonal wind and OLR at Xisha showed that intra-seasonal variability played an important role in the summer. This work improves the accuracy of the amplitude of intra-seasonal and synoptic variation obtained from remote-sensed data.
基金Project supported by the Second Stage of Brain Korea 21 Projects
文摘Many kinds of high temperature superconductor （HTS） power machines such as HTS cable, HTS fault current limitcr and HTS magnet are cooled by liquid nitrogen. The level of liquid nitrogen should be monitored and controlled to ensure the thermal stability and the dielectric strength as well. To measure the level, capacitance method and differential pressure method are usually used. However, each method has installation difficulties and measurement errors for unsteady state operation with varying system pressure. A new liquid level meter using a 2G HTS conductor is described, which has similar structure with the liquid helium level meter with NbTi filament. The level meter is fabricated with a parallel connected heater, which helps the separation of the superconducting region and normal region, considering the critical temperature, large heat capacity of conductor and cooling characteristics. The level of liquid nitrogen can be obtained from the measured voltage signal along the 2G HTS conductor. Design, fabrication and test results of the new liquid nitrogen level meter are presented.
基金Supported by Grants from the National Natural Science Foundation of China,No.30571979
文摘AIM： To study the morphology and ontogeny of dendritic cells of Peyer＇s patches in rats at different development periods. METHODS： The morphometric and flow cytometric analyses were performed to detect all the parameters of villous-crypts axis and the number of OX62＋DC, OX62＋CD4＋SIRP＋DC, and OX62＋CD4-SIRP-DC in the small intestine in different groups of rats. The relationship between the parameters of villous-axis and the number of DC and DC subtype were analyzed. RESULTS： All morphometric parameters changed significantly with the development of pups in the different age groups （F = 10.751, 12.374, 16.527, 5.291, 3.486; P = 0.000, 0.000, 0.000, 0.001, 0.015）. Villous height levels were unstable and increased from 115.24μm to 140.43 μm as early as 3 wk postpartum. Villous area increased significantly between 5 and 7 wk postpartum, peeked up to 13817.60 tam2 at 7 wk postpartum. Villous height and crypt depth ratios were relatively stable and increased significantly from 2.80 ＋ 1.01 to 4.54 =1= 1.56, 9-11 wk postpartum. The expression of OX62＋DC increased from 33.30%±5.80% to 80%± 17.30%, 3-11 wk postpartum （F =5.536, P = 0.0013）. OX62＋CD4＋SIRP＋DC subset levels detected in single-cell suspensions of rat total Peyer＇s patch dendritic cells （PP-DCs） increased significantly from 30.73% ± 5.16% to 35.50% ± 4.08%, 5-7 wk postpartum and from 34.20% ±1.35% to 43.60% ± 2.07% 9-11 wk postpartum （F = 7.216, P = 0.005）. CONCLUSION： This study confirms the agerelated changes in villous-crypt axis differentiation in the small intestine. Simultaneously, there are also development and maturation in rat PP-DCs phenotypic expression. Furthermore, the morphological changes of intestinal mucosa and the development of immune cells （especially DC） peaked at 9-11 wk postpartum, indicating that the intestinal mucosae reached a relatively mature state at 11 wk postpartum.
基金National key R&D Program of China(No.2017YFF0108104)Tianjin key R&D Program(No.20YFZCGX00550)。
文摘Attitude adjustment is a key link in the installation process of underwater facilities in deep water.To solve this problem,an omnidirectional spirit level for deep water was developed.The sealing principle of the spirit level and the principle of deep-water pressure resistance are analyzed,and the threaded connection strength is checked.The mechanical simulation verifies that the spirit level can withstand the pressure of 2000 m water depth,and the water pressure test is carried out for 30 min in a 20 MPa hyperbaric chamber.After the experiment is completed,the appearance of the spirit level is intact and there is no leakage.The experiment results show that the deep-water omnidirectional spirit level can be used in the deep sea within 2000 m.
