It has been emphasized that the assessment of residual liver function is of paramount importance to determine the following: severity of acute or chronic liver diseases independent of etiology; long-term prognosis; s...It has been emphasized that the assessment of residual liver function is of paramount importance to determine the following: severity of acute or chronic liver diseases independent of etiology; long-term prognosis; step-bystep disease progression; surgical risk; and efficacy of antiviral treatment. The most frequently used tools are the galactose elimination capacity to asses hepatocyte cytosol activity, plasma clearance of indocyanine green to assess excretory function, and antipyrine clearance to estimate microsomal activity. However, a widely accepted liver test (not necessarily a laboratory one) to assess quantitative functional hepatic reserve still needs to be established, although there have been various proposals. Furthermore, who are the operators that should order these tests? Advances in analytic methods are expected to allow quantitative liver function tests to be used in clinical practice.展开更多
Solution of the practical problems of the ice engineering requires the data about the strength of the ice cover that depends upon its temperature. In most cases, the snow lies on the ice cover and the ice temperature ...Solution of the practical problems of the ice engineering requires the data about the strength of the ice cover that depends upon its temperature. In most cases, the snow lies on the ice cover and the ice temperature differs from the atmospheric air temperature. To reveal the correlation of the air temperature with temperature on interfaces air-snow and snow-ice, the known in the thermophysics solution of the problem of the heat transfer through the multilayer plate was applied. Derived solution connects the temperature of air and temperature on the snow-ice interface and satisfactory correlates with data of the field measurements of the temperature within snow layer and ice cover and ice thickness on the Heilongjiang (Amur) River. Results of investigation are recommended for the ice temperature evaluation in engineering practice.展开更多
文摘It has been emphasized that the assessment of residual liver function is of paramount importance to determine the following: severity of acute or chronic liver diseases independent of etiology; long-term prognosis; step-bystep disease progression; surgical risk; and efficacy of antiviral treatment. The most frequently used tools are the galactose elimination capacity to asses hepatocyte cytosol activity, plasma clearance of indocyanine green to assess excretory function, and antipyrine clearance to estimate microsomal activity. However, a widely accepted liver test (not necessarily a laboratory one) to assess quantitative functional hepatic reserve still needs to be established, although there have been various proposals. Furthermore, who are the operators that should order these tests? Advances in analytic methods are expected to allow quantitative liver function tests to be used in clinical practice.
基金Reported investigations were partially supported by the Russian Foundation for Basic researches project No. 15-58-53013 FФEH a and the National Natural Science Foundation of China under contracts No. 51279122 and No. 51511130042.
文摘Solution of the practical problems of the ice engineering requires the data about the strength of the ice cover that depends upon its temperature. In most cases, the snow lies on the ice cover and the ice temperature differs from the atmospheric air temperature. To reveal the correlation of the air temperature with temperature on interfaces air-snow and snow-ice, the known in the thermophysics solution of the problem of the heat transfer through the multilayer plate was applied. Derived solution connects the temperature of air and temperature on the snow-ice interface and satisfactory correlates with data of the field measurements of the temperature within snow layer and ice cover and ice thickness on the Heilongjiang (Amur) River. Results of investigation are recommended for the ice temperature evaluation in engineering practice.