基于深度强化学习的VR大数据智能测评方法

为实现对VR(虚拟现实)大数据的精准测评,保证测评结果更贴合实际,提出深度强化学习VR大数据的智能测评方法。首先,集中筛查VR大数据智能测评指标,使用Bartlett球形工具,检验指标的可靠度;然后,引进深度强化学习,对测评中的特征性因子进行智能拟合,保证测评结果的一致性;最后,通过回归模型设定一个测评标准值与回归系数,按照回归计算中的一致性计算公式,对测评结果进行评估,实现VR大数据智能测评结果校正。实验结果表明,所提的测评方法在实际应用中,能够实现对不同VR大数据测评的高度一致性,并且得出的测评结果与实际更相符。

基于改进决策树算法的大学生心理健康智能测评方法研究

大学生心理健康智能测评由于仅对影响因素数据进行属性划分,导致方法的测评准确率较低。因此,文章设计了基于改进决策树算法的大学生心理健康智能测评方法。对获取的大学生心理健康原始数据进行数据清洗和数据选择,得到质量更高的数据集,构建相对应的大学生心理健康测评架构,将大学生的心理健康状态划分为健康、轻度不健康和不健康三种,并计算测评方法的分类性能,利用改进决策树算法的特性,筛选和优化测评因子,再通过计算对测评因子进行赋值,得到测评因子的拟合结果,通过对大学生心理健康的影响因素数据进行属性划分和赋值,并对其进行归一化计算,实现大学生心理健康测评的智能化。通过上述的设计,完成对大学生心理健康智能测评方法的设计。在实验测试中,和以往的大学生心理健康智能测评方法相比,基于改进决策树算法的大学生心理健康智能测评方法测评准确率为97.82%,测评准确率更高。

师范类学生心理健康品质性别差异显著性研究

基于数据挖掘技术,对师范类学生不同性别心理健康品质的差异性进行了研究。充分考虑了心理健康品质测评数据信息的分布特征,通过引入独立样本Mann-Whitney U检验和独立样本Moses极端反应检验两种算法,对师范类学生不同性别心理健康品质差异的显著性进行分析。

Upper gastrointestinal bleeding etiology score for predicting variceal and non-variceal bleeding

AIM： To identify clinical parameters, and develop an Upper Gastrointesinal Bleeding （UGIB） Etiology Score for predicting the types of UGIB and validate the score. METHODS： Patients with UGIB who underwent endoscopy within 72 h were enrolled. Clinical and basic laboratory parameters were prospectively collected. Predictive factors for the types of UGIB were identified by univariate and multivariate analyses and were used to generate the UGIB Etiology Score. The best cutoff of the score was defined from the receiver operating curve and prospectively validated in another set of patients with UGIB. RESULTS： Among 261 patients with UGIB, 47 （18%） had variceal and 214 （82%） had non-variceal bleeding. Univariate analysis identified 27 distinct parameters significantly associated with the types of UGIB. Logistic regression analysis identified only 3 independent factors for predicting variceal bleeding; previous diagnosis of cirrhosis or signs of chronic liver disease （OR 22.4, 95% CI 8.3-60.4, P 〈 0.001）, red vomitus （OR 4.6, 95% CI 1.8-11.9, P = 0.02）, and red nasogastric （NG） aspirate （OR 3.3, 95% CI 1.3-8.3, P = 0.011）. The UGIB Etiology Score was calculated from （3.1× previous diagnosis of cirrhosis or signs of chronic liver disease） ＋ （1.5× red vomitus） ＋ （1.2× red NG aspirate）, when 1 and 0 are used for the presence and absence of each factor, respectively. Using a cutoff ≥ 3.1, the sensitivity, specificity, accuracy, positive predictive value （PPV）, and negative predictive value （NPV） in predicting variceal bleeding were 85%, 81%, 82%, 50%, and 96%, respectively. The score was prospectively validated in cases （46 variceal and 149 another set of 195 UGIB non-variceal bleeding）. The PPV and NPV of a score ≥ 3.1 for variceal bleeding were 79% and 97%, respectively. CONCLUSION： The UGIB Etiology Score, composed of 3 parameters, using a cutoff ≥ 3.1 accurately predicted variceal bleeding and may help to guide the choice of initial therapy for UGIB before endoscopy.

Affective Meaning of Pronouns in a Russian Sample

The present study examines affective meaning of pronouns （in Russian） represented by the semantic differential. Of direct relevance to the present study is the theory of affective meaning propounded by Osgood. Two hypotheses were tested. According to a ＂magnitude＂ hypothesis, affective dimensions （each of evaluation, potency, and activity taken separately） differ in their magnitude across pronouns I, My, Me, and They. A ＂structural＂ hypothesis stated that the affective dimensions yield latent factors across （the generality） and within （the concept-scale interaction） the pronoun concepts. Repeated-measures analysis of variance （1-way ANOVA） and confirmatory factor analysis were employed to process data. It was found that each of the evaluation and potency measures yield a significant magnitude change across the pronouns, but there was indicated no significant change across the pronouns with respect to the activity dimension. Therewith, the pronoun My gained a salient value and the pronoun They the smallest value. Using confirmatory factor analysis five models were tested. Among them one model was good fit to the data. It engaged a four-factor solution resulted in that four pronouns are latent affective distinct but related factors and the evaluation, potency, and activity are their indicators.

观察饮食干预为主的家庭支持护理对血液透析患者预后的影响

研究血液透析(Hemodialysis,HD)病患接受饮食干预为主的家庭支持护理对其预后的影响。方法:列入2019年3月-2020年3月于我院HD治疗并护理的病患60例,通过全盲抽签方式将其分为常例干预、协同支持两组,组均30例。常例干预组病患接受常规方案护理;协同支持组增加以饮食干预为主的家庭支持护理干预。对比两组病患的相关因子测评值(负性心理测评值、生活水平测评值)及其对护理干预的满意认可度。结果:两组病患干预前的负性心理测评值比对数据均不具备差异性统计区别(P>0.05),接受干预后负性情绪测评值均降低,且协同支持组病患的负性心理测评值均显著低于常例干预组病患的负性心理测评值;协同支持组病患的生活水平测评值显著高于常例干预组病患的生活水平测评值;协同支持组病患对干预的满意认可度(96.66%)显著高于常例干预组病患对干预的满意认可度(73.33%),比对数据具备差异性统计区别(P<0.05)。结论:HD治疗的病患在常规护理中增加以饮食干预为主的家庭支持护理干预,病患预后的心理状态更佳,对干预服务的认可度更高,生活水平得到改善,推荐使用。

Vascular endothelial growth factor and microvessel density for detection and prognostic evaluation of invasive breast cancer

Objective The purpose of this study was to evaluate the distribution of vascular endothelial growth factor （VEGF） and CD105-microvessel density （MVD）in invasive breast carcinomas. We also aimed to analyze the relationship between VEGF and MVD expression with other standard prognostic parameters associated with invasive breast cancer, such as size, grade, stage of the cancer, metastases, and tumor recurrence. Methods immunohistochemistry via the Ultra SensitiveTM S-P method was used to detect VEGF and MVD expression in 128 cases of invasive breast carcinoma. Specimens were evaluated for CD105 expression. Positively stained microvessels were counted in dense vascular loci under 400x magnification, MVD in the peripheral area adjacent to the lesion and in the central, area within the lesion in invasive breast carcinomas and benign leisions groups were also assessed. Fifty cases of benign breast disease tissue were selected as the control group. Results Results showed that 64.1% of invasive breast cancer samples were VEGF-positive, higher than in benign breast disease tissue （22.0%, P 〈 0.05）. There was a positive correlation between VEGF overexpression and histological grade, lymph node metastasis, and distant metastasis of invasive breast cancer. VEGF expression was not related to age or size of the tumor （P 〉 0.05）. MVD of the peripheral area adjacent to the lesion was significantly higher than those central area within the lesion in both invasive breast cancer and benignbreast disease groups （P 〈 0.01 for each group）. There were significant differences in the mean CD105-MVD, between invasive breast tumors with a histological grade of Ⅰ or Ⅱ and grade Ⅲ; between tumors with lymph node or distant metastasis; and between patients with or without recurrence （P 〈 0.05）. However, there was no difference in the mean MVD between the two age groups （≤ 50 years vs. 〉 50 years） or the two tumor diameter groups （〈 2 cm vs. 〉 2 cm）, P 〉 0.05. Conclusion Overexpression of VEGF and MVD may be important biological.markers for invasion and lymph node and distant metastases of invasive breast cancer. Combined detection of the two tumor markers could provide better prognostic monitoring for disease recurrence and metastasis, as well as aid with clinical staging of breast tumors. Prediction of the risk for metastasis and recurrence, as well as recurrence patterns based on VEGF and MVD post-surgery, could aid design of better follow-up regimens and appropriate treatment strategies for breast cancer patients.

Influence of herbal cake-partitioned moxibustion on lumbar functions and inflammatory factors in patients with lumbar disc herniation due to kidney deficiency and blood stasis

Objective To observe the efficacy of herbal cake-partitioned moxibustion for lumbar disc herniation(LDH)due to kidney deficiency and blood stasis and observe the influence of this method on lumbar functions and inflammatory factors in patients with this condition.Methods A total of 120 LDH patients who met the inclusion criteria were randomly divided into three groups,including a herbal cake-partitioned moxibustion group,a flour cake-partitioned moxibustion group,and a Western medication group,with 40 patients in each group.The patients in the Western medication group were treated with diflunisal tablets,0.5 g per dose,2 doses a day.Those in the herbal cake-partitioned moxibustion group were treated with additional herbal cake-partitioned moxibustion group at Back-Shu Points and Jiaji(EX-B2)Points once a day.Those in the flour cake-partitioned moxibustion group were treated with the same methods as in the herbal cake-partitioned moxibustion group,except that the herbal cake was replaced by a flour cake.All the patients were treated for 10 d.After treatment,the scores of the visual analog scale(VAS)and Japanese Orthopaedic Association(JOA)and the changes of the interleukin(IL)-6,tumor necrosis factor(TNF)-α,and substance P(SP)levels were observed,and the efficacy was evaluated.Results After treatment,the VAS score and the levels of IL-6,TNF-α,and SP were lower than those before treatment,and the JOA score was higher than that before treatment in the three groups,indicating intra-group statistical significance(P<0.05).The VAS score and the levels of IL-6,TNF-α,and SP of the herbal cake-partitioned moxibustion group were lower than those of the flour cake-partitioned moxibustion group and the Western medication group,while the JOA score of the herbal cake-partitioned moxibustion group was higher than that of the other two groups,indicating inter-group statistical significance(P<0.05).The total effective rate of the herbal cake-partitioned moxibustion group was 92.5%,higher than that of the flour cake-partitioned moxibustion group(80.0%)and the Western medication group(72.5%),indicating inter-group statistical significance(P<0.05).Conclusion On the basis of Western oral medication,additional herbal cake-partitioned moxibustion can alleviate the pain and improve the lumbar functions in patients with LDH due to kidney deficiency and blood stasis.The efficacy of the integrated method is better than that of either flour cake-partitioned moxibustion or Western medication alone,which may be related to the reduction of serum inflammatory factors.

安宁疗护在恶性血液病患者护理中的应用及对生活质量的影响分析

研究恶性血液病病患接受安宁疗护干预的效果影响分析。方法:选入2018年2月-2021年2月我院诊治护理的30例恶性血液病病患,通过双盲掷骰子法将其分为常例方案组及安宁分析组,每组均15例。常例方案组病患采用常规方案干预;安宁分析组采用安宁疗护措施。比较常例方案、安宁分析两组病患干预后的相关因子测评值。结果:安宁分析组病患的相关因子测评值均显著优于常例方案组病患的相关因子测评值,数据具备统计差异P<0.05。结论:安宁疗护可以有效配合治疗,降低护理过程中病患的情绪波动影响,提升其预后生活质量,推荐使用。

Efficacy of mild moxibustion combined with surgery for meniscal injury and its effect on TGF-β1 and PDGF levels in the fluid of knee joint

Objective To observe the efficacy of mild moxibustion combined with arthroscopic meniscal repair in the treatment of meniscal injury and to explore its action mechanism.Methods Ninety-eight patients with meniscal injury were divided into a surgery group and a moxibustion plus surgery group by the random number table method,with 49 cases in each group.Both groups received arthroscopic meniscal repair,and the moxibustion plus surgery group was treated with add-on mild moxibustion.The Lysholm score,visual analog scale(VAS)score,and mobility of the affected knee were measured before and after treatment,and transforming growth factor(TGF)-β1 and platelet-derived growth factor(PDGF)levels were measured in the fluid of the affected knee joint.The healing of the meniscus was recorded at a follow-up visit 3 months after the surgery.Results After treatment,the Lysholm score increased,the VAS score decreased in both groups,and the intra-group differences in both groups were statistically significant(P<0.05).The Lysholm score was higher in the moxibustion plus surgery group than in the surgery group,and the VAS score was lower in the moxibustion plus surgery group than in the surgery group.The differences between groups in both scores were statistically significant(P<0.05).The mobility of the affected knee joint increased in both groups(P<0.05),and it was greater in the moxibustion plus surgery group than in the surgery group(P<0.05).When compared with pretreatment,the levels of TGF-β1 and PDGF in the fluid of the knee joint increased in both groups(P<0.05),and the levels of TGF-β1 and PDGF in the fluid of the affected knee joint were higher in the moxibustion plus surgery group than in the surgery group(P<0.05).The healing of the meniscus in the moxibustion plus surgery group was significantly better than that in the surgery group at the follow-up visit 3 months after the surgery(P<0.05).Conclusion The effect of mild moxibustion combined with arthroscopic meniscal repair is better than the surgery alone in improving knee function,relieving pain,increasing mobility of the affected knee,and promoting meniscal healing,which may be related to the up-regulation of TGF-β1 and PDGF levels in the fluid of knee joint.