AIM： To evaluate the effectiveness of a rapid and easy fingertip whole blood point-of-care test for celiac disease （CD） case finding and diet monitoring. METHODS： Three hundred individuals, 206 females （68.7%） a...AIM： To evaluate the effectiveness of a rapid and easy fingertip whole blood point-of-care test for celiac disease （CD） case finding and diet monitoring. METHODS： Three hundred individuals, 206 females （68.7%） and 94 males （31.3%）, were submitted to a rapid and easy immunoglobulin-A-dass fingertip whole blood point-of-care test in the doctor＇s office in order to make immediate clinical decisions： 13 healthy controls, 6 with CD suspicion, 46 treated celiacs, 84 relatives of the celiac patients, 69 patients with dyspepsia, 64 with irritable bowel syndrome （IBS）, 8 with Crohn＇s disease and 9 with other causes of diarrhea. RESULTS： Upper gastrointestinal endoscopy with duodenal biopsies was performed in patients with CD suspicion and in individuals with positive test outcome： in 83.3% （5/6） of the patients with CD suspicion, in 100% of the patients that admitted gluten-free diet transgressions （6/6）, in 3.8% of first-degree relatives （3/79） and in 2.9% of patients with dyspepsia （2/69）. In all these individuals duodenal biopsies confirmed CD （Marsh＇s histological classification）. The studied test showed good correlation with serologic antibodies, endoscopic and histological findings.CONCLUSION： The point-of-care test was as reliable as conventional serological tests in detecting CD cases and in CD diet monitoring.展开更多
The part 23 airworthiness standards for small airplanes states minimal standards of the emergency condition for the occupant protection. Under this regulation, the airplane must be designed and certified about static ...The part 23 airworthiness standards for small airplanes states minimal standards of the emergency condition for the occupant protection. Under this regulation, the airplane must be designed and certified about static strength of the fuselage and seats, horizontal and vertical dynamic strength of seats. Human injuries in dynamic crash tests and the survivability in the turnover condition should be also evaluated. The most important part among injuries of human is a head and the head injury is evaluated by Head Injury Criterion （HIC）. KC-100, 4 seats airplane that is manufactured by KAI, was conducted seat dynamic tests. The HIC from tests was well within criteria limits 1,000 and the occupant compartment for head protection provided hazard-free spaces in the occupant＇s head strike envelope for the frontal-horizontal crash impacts. The airplane also was conducted a turnover static test and analysis to especially show living spaces of the head. The airframe could sustain living spaces for occupants in the turnover condition and occupants could escape and be protected. The results of tests and analysis corresponded to the criteria and proved the retention of survivable space in emergency landing condition.展开更多
Purpose： Suicide becomes a serious problem in today＇s society and hanging is a common method of suicide. We want to find the factors which can predict the final functional outcomes of these cases. Methods： All pati...Purpose： Suicide becomes a serious problem in today＇s society and hanging is a common method of suicide. We want to find the factors which can predict the final functional outcomes of these cases. Methods： All patients who presented to Accident and Emergency Department （ED） of the National Cheng Kung University Hospital from 1st January 2005 to 31th December 2013 with a hanging injury were included in this study. All cases were divided into good outcome group and bad outcome group according to Glasgow Outcome Scale （GOS）. Data was analyzed by Mann-Whitney test and chi-square test. Results： Glasgow Coma Scale （GCS） 〈 3, pupil dilation and no pupillary light reflex both at the scene and ED were the factors to indicate poor functional outcome. Out-hospital cardiac arrest （OHCA）, acidosis （pH 〈 Z2） and the need for intubation once arriving at ED were also related to poor functional outcome. OHCA cases all had poor functional outcome, Conclusion： GCS, pupil size, pupiUary light reflex, OHCA and acidosis are useful as prognostic factors. GCS= 3 lead to a very poor outcome. However, the functional outcome seems good in patients with GCS〉3. There parameters can help to predict the outcome before treatment.展开更多
基金Supported by Pontifical Catholic University of Paraná
文摘AIM： To evaluate the effectiveness of a rapid and easy fingertip whole blood point-of-care test for celiac disease （CD） case finding and diet monitoring. METHODS： Three hundred individuals, 206 females （68.7%） and 94 males （31.3%）, were submitted to a rapid and easy immunoglobulin-A-dass fingertip whole blood point-of-care test in the doctor＇s office in order to make immediate clinical decisions： 13 healthy controls, 6 with CD suspicion, 46 treated celiacs, 84 relatives of the celiac patients, 69 patients with dyspepsia, 64 with irritable bowel syndrome （IBS）, 8 with Crohn＇s disease and 9 with other causes of diarrhea. RESULTS： Upper gastrointestinal endoscopy with duodenal biopsies was performed in patients with CD suspicion and in individuals with positive test outcome： in 83.3% （5/6） of the patients with CD suspicion, in 100% of the patients that admitted gluten-free diet transgressions （6/6）, in 3.8% of first-degree relatives （3/79） and in 2.9% of patients with dyspepsia （2/69）. In all these individuals duodenal biopsies confirmed CD （Marsh＇s histological classification）. The studied test showed good correlation with serologic antibodies, endoscopic and histological findings.CONCLUSION： The point-of-care test was as reliable as conventional serological tests in detecting CD cases and in CD diet monitoring.
文摘The part 23 airworthiness standards for small airplanes states minimal standards of the emergency condition for the occupant protection. Under this regulation, the airplane must be designed and certified about static strength of the fuselage and seats, horizontal and vertical dynamic strength of seats. Human injuries in dynamic crash tests and the survivability in the turnover condition should be also evaluated. The most important part among injuries of human is a head and the head injury is evaluated by Head Injury Criterion （HIC）. KC-100, 4 seats airplane that is manufactured by KAI, was conducted seat dynamic tests. The HIC from tests was well within criteria limits 1,000 and the occupant compartment for head protection provided hazard-free spaces in the occupant＇s head strike envelope for the frontal-horizontal crash impacts. The airplane also was conducted a turnover static test and analysis to especially show living spaces of the head. The airframe could sustain living spaces for occupants in the turnover condition and occupants could escape and be protected. The results of tests and analysis corresponded to the criteria and proved the retention of survivable space in emergency landing condition.
文摘Purpose： Suicide becomes a serious problem in today＇s society and hanging is a common method of suicide. We want to find the factors which can predict the final functional outcomes of these cases. Methods： All patients who presented to Accident and Emergency Department （ED） of the National Cheng Kung University Hospital from 1st January 2005 to 31th December 2013 with a hanging injury were included in this study. All cases were divided into good outcome group and bad outcome group according to Glasgow Outcome Scale （GOS）. Data was analyzed by Mann-Whitney test and chi-square test. Results： Glasgow Coma Scale （GCS） 〈 3, pupil dilation and no pupillary light reflex both at the scene and ED were the factors to indicate poor functional outcome. Out-hospital cardiac arrest （OHCA）, acidosis （pH 〈 Z2） and the need for intubation once arriving at ED were also related to poor functional outcome. OHCA cases all had poor functional outcome, Conclusion： GCS, pupil size, pupiUary light reflex, OHCA and acidosis are useful as prognostic factors. GCS= 3 lead to a very poor outcome. However, the functional outcome seems good in patients with GCS〉3. There parameters can help to predict the outcome before treatment.
