目的:检测四方格移步测试(four square step test,FSST)中文版在评定脑卒中患者平衡能力的信效度。方法:首次发病的脑卒中患者(最终入组30例)完成了本试验,受试者进行FSST,Berg平衡量表(Berg balance scale,BBS),起立-行走计时测试(time...目的:检测四方格移步测试(four square step test,FSST)中文版在评定脑卒中患者平衡能力的信效度。方法:首次发病的脑卒中患者(最终入组30例)完成了本试验,受试者进行FSST,Berg平衡量表(Berg balance scale,BBS),起立-行走计时测试(timed up and go test,TUGT)和10m步行测试(10 meter walk test,10MWT),48h内完成第二次FSST测试,对其结果进行信度和效度分析。结果:FSST中文版量表的评定者间信度检验总体ICC值为0.89(95%CI:0.87—0.92),重测信度检验显示总体ICC值为0.98(95%CI:0.96—0.99);通过Spearman相关分析,结果显示FSST与BBS量表呈中等程度负相关(r=-0.62,P<0.001),与10MWT评分结果呈良好正相关性(r=0.87,P<0.001),与TUGT评分结果呈良好正相关性(r=0.86,P<0.001)。结论:FSST中文版在用于国内脑卒中患者平衡功能时评定时具有良好的信度与效度,建议可在临床推广使用。展开更多
最新的GPT系列产品,让人们更加憧憬认知能力远远超过人类的通用AI。与此同时,一些伦理学家认为应该赋予人工智能以道德地位,让它们能为自己的行为负责。斯派洛通过构造“图灵分类测试”的思想实验反对以普特南为代表的计算功能主义的观...最新的GPT系列产品,让人们更加憧憬认知能力远远超过人类的通用AI。与此同时,一些伦理学家认为应该赋予人工智能以道德地位,让它们能为自己的行为负责。斯派洛通过构造“图灵分类测试”的思想实验反对以普特南为代表的计算功能主义的观点,同时也反对构建道德机器。他认为AI缺乏本体论意义上“内在生命”,也不具有惩罚的可能性,从而也不具备道德地位。但是,在斯派洛的思想实验中,并没有严格区分“道德能动者”和“道德承受者”,以致于在斯派洛的论证中,对AI道德地位的界定是模糊的。尽管如此,斯派洛的思想实验仍具有启发性意义。The latest GPT series products make people more hopeful about general AI whose cognitive ability far exceeds that of humans. At the same time, some ethicists argue that AI should be given moral status, holding them responsible for their actions. Sparrow opposed Putnam’s view of computational functionalism through his thought experiment of constructing the Turing triage test, as well as the construction of a moral machine. He argues that AI lacks an “inner life” in an ontological sense, has no “potential for punishment,” and thus has no moral standing. However, in Sparrow’s thought experiment, there is no strict distinction between “moral agent” and “moral patient”, so that in Sparrow’s argument, the definition of AI’s moral status is vague. Still, Sparrow’s thought experiment is instructive.展开更多
香港特区政府化验所生化组自1991年起参加美国CTS(Collaboraive Testing Service Inc)和英国Cellmark Di-agnostics的资格测试,历年均合格.他们通过了ASCLD(American Society of Crime Laboratory Directors)的质量保证体系认证.ASCLD...香港特区政府化验所生化组自1991年起参加美国CTS(Collaboraive Testing Service Inc)和英国Cellmark Di-agnostics的资格测试,历年均合格.他们通过了ASCLD(American Society of Crime Laboratory Directors)的质量保证体系认证.ASCLD的认证是极为严格的,通过后还定期进行检查,通过ASCLD认证的实验室出具的检验报告非常具有权威性.以下对他们的质量保证体系进行简介(参照其《质量保证手册》).1 人员化验所生化组由15人组成,分级很明确,有两名高级化验师、5名化验师和8名技术员组成,高级化验师负责全组的行政及技术管理工作,具体案件分发给化验师.每个化验师带1名技术员,化验师指导技术员做具体检验工作.任何新到生化组的人员都要经过培训,盲测达标后才能上岗.每年全组人员还要参加国际性的资格测试.展开更多
AIM: To determine if the observed paracellular sucrose leak in Barrett's esophagus patients is due to their pro- ton pump inhibitor (PPI) use. METHODS: The in vivo sucrose permeability test was administered to he...AIM: To determine if the observed paracellular sucrose leak in Barrett's esophagus patients is due to their pro- ton pump inhibitor (PPI) use. METHODS: The in vivo sucrose permeability test was administered to healthy controls, to Barrett's patients and to non-Barrett's patients on continuous PPI thera- py. Degree of leak was tested for correlation with pres- ence of Barrett's, use of PPIs, and length of Barrett's segment and duration of PPI use. RESULTS: Barrett's patients manifested a near 3-fold greater, upper gastrointestinal sucrose leak than healthy controls. A decrease of sucrose leak was ob- served in Barrett's patients who ceased PPI use for 7 d.Although initial introduction of PPI use (in a PPI-na'ive population) results in dramatic increase in sucrose leak, long-term, continuous PPI use manifested a slow spon- taneous decline in leak. The sucrose leak observed in Barrett's patients showed no correlation to the amount of Barrett's tissue present in the esophagus. CONCLUSION: Although future research is needed to determine the degree of paracellular leak in actual Barrett's mucosa, the relatively high degree of leak ob- served with in vivo sucrose permeability measurement of Barrett's patients reflects their PPI use and not their Barrett's tissue perse.展开更多
The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existi...The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existing test methods and with modified equipment and methods. The results indicate the current test tray is inadequate and that a thicker tray provides better results. Conditioning that incorporated either freeze times between 4 to 8 hours and/or freeze thaw cycles were also found to be improvements to the current conditioning methods. The specified mass of the steel spheres used during the test may be too restrictive in that more economical spheres were tested and did not show differences in aggregate loss.展开更多
Many stock exchanges around the world enforcing daily price limits on the amount asset prices can change to prevent the market from overreacting and to reduce volatility. Price limits are artificial boundaries set by ...Many stock exchanges around the world enforcing daily price limits on the amount asset prices can change to prevent the market from overreacting and to reduce volatility. Price limits are artificial boundaries set by market regulators who restrict price changes of a stock to a pre-specified range during a trading day or a single trading session. The primary aim of price limit rules is to stabilize the markets during panic trading, to moderate vitality by repressing excessive speculation, and to allow stocks to be traded at prices close to their fair value. However, their impact on the market is a somewhat unresolved issue (Harris, 1998). Using a methodology of comparing volatility based on the extreme value technique, the authors empirically investigate the impact of price limits on the volatility of the Stock Exchange of Thailand. The empirical results support price limits advocates, suggesting that price limits rules moderate stock price volatility.展开更多
The reinforcement effect of a reconstruction scheme for a steel factory building was investigated using finite element method and dynamic performance test. The workshop concerned is a portal frame structure with four ...The reinforcement effect of a reconstruction scheme for a steel factory building was investigated using finite element method and dynamic performance test. The workshop concerned is a portal frame structure with four spans and two slope roofs, of which ten columns need cutting for expanding span. The design and reconstruction project of column-cut supported by joist were introduced, which includes column reinforcement, connection rebuilding between brackets and crane beams, and the changing of rigid joint into hinge joint. The construction scheme was put forward in the light of the characteristics of the reinforcement and reconstruction. Spot test of dynamic performance on the workshop and comparison with theoretical analysis results show that the column-cut supported by joist design is effective and the reconstruction project is successful.展开更多
文摘目的:检测四方格移步测试(four square step test,FSST)中文版在评定脑卒中患者平衡能力的信效度。方法:首次发病的脑卒中患者(最终入组30例)完成了本试验,受试者进行FSST,Berg平衡量表(Berg balance scale,BBS),起立-行走计时测试(timed up and go test,TUGT)和10m步行测试(10 meter walk test,10MWT),48h内完成第二次FSST测试,对其结果进行信度和效度分析。结果:FSST中文版量表的评定者间信度检验总体ICC值为0.89(95%CI:0.87—0.92),重测信度检验显示总体ICC值为0.98(95%CI:0.96—0.99);通过Spearman相关分析,结果显示FSST与BBS量表呈中等程度负相关(r=-0.62,P<0.001),与10MWT评分结果呈良好正相关性(r=0.87,P<0.001),与TUGT评分结果呈良好正相关性(r=0.86,P<0.001)。结论:FSST中文版在用于国内脑卒中患者平衡功能时评定时具有良好的信度与效度,建议可在临床推广使用。
文摘最新的GPT系列产品,让人们更加憧憬认知能力远远超过人类的通用AI。与此同时,一些伦理学家认为应该赋予人工智能以道德地位,让它们能为自己的行为负责。斯派洛通过构造“图灵分类测试”的思想实验反对以普特南为代表的计算功能主义的观点,同时也反对构建道德机器。他认为AI缺乏本体论意义上“内在生命”,也不具有惩罚的可能性,从而也不具备道德地位。但是,在斯派洛的思想实验中,并没有严格区分“道德能动者”和“道德承受者”,以致于在斯派洛的论证中,对AI道德地位的界定是模糊的。尽管如此,斯派洛的思想实验仍具有启发性意义。The latest GPT series products make people more hopeful about general AI whose cognitive ability far exceeds that of humans. At the same time, some ethicists argue that AI should be given moral status, holding them responsible for their actions. Sparrow opposed Putnam’s view of computational functionalism through his thought experiment of constructing the Turing triage test, as well as the construction of a moral machine. He argues that AI lacks an “inner life” in an ontological sense, has no “potential for punishment,” and thus has no moral standing. However, in Sparrow’s thought experiment, there is no strict distinction between “moral agent” and “moral patient”, so that in Sparrow’s argument, the definition of AI’s moral status is vague. Still, Sparrow’s thought experiment is instructive.
文摘香港特区政府化验所生化组自1991年起参加美国CTS(Collaboraive Testing Service Inc)和英国Cellmark Di-agnostics的资格测试,历年均合格.他们通过了ASCLD(American Society of Crime Laboratory Directors)的质量保证体系认证.ASCLD的认证是极为严格的,通过后还定期进行检查,通过ASCLD认证的实验室出具的检验报告非常具有权威性.以下对他们的质量保证体系进行简介(参照其《质量保证手册》).1 人员化验所生化组由15人组成,分级很明确,有两名高级化验师、5名化验师和8名技术员组成,高级化验师负责全组的行政及技术管理工作,具体案件分发给化验师.每个化验师带1名技术员,化验师指导技术员做具体检验工作.任何新到生化组的人员都要经过培训,盲测达标后才能上岗.每年全组人员还要参加国际性的资格测试.
基金Supported by Sharpe-Strumia Research Foundation of the Bryn Mawr Hospital
文摘AIM: To determine if the observed paracellular sucrose leak in Barrett's esophagus patients is due to their pro- ton pump inhibitor (PPI) use. METHODS: The in vivo sucrose permeability test was administered to healthy controls, to Barrett's patients and to non-Barrett's patients on continuous PPI thera- py. Degree of leak was tested for correlation with pres- ence of Barrett's, use of PPIs, and length of Barrett's segment and duration of PPI use. RESULTS: Barrett's patients manifested a near 3-fold greater, upper gastrointestinal sucrose leak than healthy controls. A decrease of sucrose leak was ob- served in Barrett's patients who ceased PPI use for 7 d.Although initial introduction of PPI use (in a PPI-na'ive population) results in dramatic increase in sucrose leak, long-term, continuous PPI use manifested a slow spon- taneous decline in leak. The sucrose leak observed in Barrett's patients showed no correlation to the amount of Barrett's tissue present in the esophagus. CONCLUSION: Although future research is needed to determine the degree of paracellular leak in actual Barrett's mucosa, the relatively high degree of leak ob- served with in vivo sucrose permeability measurement of Barrett's patients reflects their PPI use and not their Barrett's tissue perse.
文摘The objective of this paper is to evaluate the Vialit Adhesion Test and its potential for use within performance oriented specifications for seal treatments. Multiple aggregates and emulsions are evaluated with existing test methods and with modified equipment and methods. The results indicate the current test tray is inadequate and that a thicker tray provides better results. Conditioning that incorporated either freeze times between 4 to 8 hours and/or freeze thaw cycles were also found to be improvements to the current conditioning methods. The specified mass of the steel spheres used during the test may be too restrictive in that more economical spheres were tested and did not show differences in aggregate loss.
文摘Many stock exchanges around the world enforcing daily price limits on the amount asset prices can change to prevent the market from overreacting and to reduce volatility. Price limits are artificial boundaries set by market regulators who restrict price changes of a stock to a pre-specified range during a trading day or a single trading session. The primary aim of price limit rules is to stabilize the markets during panic trading, to moderate vitality by repressing excessive speculation, and to allow stocks to be traded at prices close to their fair value. However, their impact on the market is a somewhat unresolved issue (Harris, 1998). Using a methodology of comparing volatility based on the extreme value technique, the authors empirically investigate the impact of price limits on the volatility of the Stock Exchange of Thailand. The empirical results support price limits advocates, suggesting that price limits rules moderate stock price volatility.
基金Supported by Program for New Century Excellent Talents in University (No. NCET-06-0228)
文摘The reinforcement effect of a reconstruction scheme for a steel factory building was investigated using finite element method and dynamic performance test. The workshop concerned is a portal frame structure with four spans and two slope roofs, of which ten columns need cutting for expanding span. The design and reconstruction project of column-cut supported by joist were introduced, which includes column reinforcement, connection rebuilding between brackets and crane beams, and the changing of rigid joint into hinge joint. The construction scheme was put forward in the light of the characteristics of the reinforcement and reconstruction. Spot test of dynamic performance on the workshop and comparison with theoretical analysis results show that the column-cut supported by joist design is effective and the reconstruction project is successful.