Updated version of local non-equilibrium diffusion model (LNDM) for rapid solidification of binary alloys was considered. The LNDM takes into account deviation from local equilibrium of solute concentration and solu...Updated version of local non-equilibrium diffusion model (LNDM) for rapid solidification of binary alloys was considered. The LNDM takes into account deviation from local equilibrium of solute concentration and solute flux fields in bulk liquid. The exact solutions for solute concentration and flux in bulk liquid were obtained using hyperbolic diffusion equations. The results show the transition from diffusion-limited to purely thermally controlled solidification with effective diffusion coefficient →0 and complete solute trapping KLNDM(v)→1 at v→vDb for any kind of solid-liquid interface kinetics. Critical parameter for diffusionless solidification and complete solute trapping is the diffusion speed in bulk liquid vDb. Different models for solute trapping at the interface with different interface kinetic approaches were considered.展开更多
In this paper a finite element model is developed to study cytosolic calcium concen- tration distribution in astrocytes for a two-dimensional steady-state case in presence of excess buffer. The mathematical model of c...In this paper a finite element model is developed to study cytosolic calcium concen- tration distribution in astrocytes for a two-dimensional steady-state case in presence of excess buffer. The mathematical model of calcium diffusion in astrocytes leads to a boundary value problem involving elliptical partial differential equation. The model con- sists of reaction-diffusion phenomena, association and dissociation rates and buffer. A point source of calcium is incorporated in the model. Appropriate boundary conditions have been framed. Finite element method is employed to solve the problem. A MATLAB program has been developed for the entire problem and simulated to compute the numer- ical results. The numerical results have been used to plot calcium concentration profiles in astrocytes. The effect of ECTA, BAPTA and aCa influx on calcium concentration distribution in astrocytes is studied with the help of numerical results.展开更多
文摘Updated version of local non-equilibrium diffusion model (LNDM) for rapid solidification of binary alloys was considered. The LNDM takes into account deviation from local equilibrium of solute concentration and solute flux fields in bulk liquid. The exact solutions for solute concentration and flux in bulk liquid were obtained using hyperbolic diffusion equations. The results show the transition from diffusion-limited to purely thermally controlled solidification with effective diffusion coefficient →0 and complete solute trapping KLNDM(v)→1 at v→vDb for any kind of solid-liquid interface kinetics. Critical parameter for diffusionless solidification and complete solute trapping is the diffusion speed in bulk liquid vDb. Different models for solute trapping at the interface with different interface kinetic approaches were considered.
文摘In this paper a finite element model is developed to study cytosolic calcium concen- tration distribution in astrocytes for a two-dimensional steady-state case in presence of excess buffer. The mathematical model of calcium diffusion in astrocytes leads to a boundary value problem involving elliptical partial differential equation. The model con- sists of reaction-diffusion phenomena, association and dissociation rates and buffer. A point source of calcium is incorporated in the model. Appropriate boundary conditions have been framed. Finite element method is employed to solve the problem. A MATLAB program has been developed for the entire problem and simulated to compute the numer- ical results. The numerical results have been used to plot calcium concentration profiles in astrocytes. The effect of ECTA, BAPTA and aCa influx on calcium concentration distribution in astrocytes is studied with the help of numerical results.