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Survivin在脑膜瘤的表达特点及其预测预后的价值 被引量:4
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作者 焦建同 黄进 +4 位作者 程超 黄维一 王龙 赵一清 邵君飞 《临床神经外科杂志》 CAS 2018年第4期241-245,共5页
目的探讨survivin在脑膜瘤的表达特点及其与预后的关系。方法采用免疫组化法检测121例脑膜瘤患者手术切除的脑膜瘤标本的survivin表达水平;并收集患者的临床资料,分析survivin浓度分布评分(IDS)与临床指标的关系。结果 WHOⅠ、Ⅱ、Ⅲ级... 目的探讨survivin在脑膜瘤的表达特点及其与预后的关系。方法采用免疫组化法检测121例脑膜瘤患者手术切除的脑膜瘤标本的survivin表达水平;并收集患者的临床资料,分析survivin浓度分布评分(IDS)与临床指标的关系。结果 WHOⅠ、Ⅱ、Ⅲ级脑膜瘤患者的survivin IDS分别是3.05±3.21、7.86±2.19和10.00±1.87,Ⅱ、Ⅲ级脑膜瘤患者的survivin IDS明显高于Ⅰ级脑膜瘤(均P<0.001)。无复发和复发、未死亡和死亡患者的survivin IDS分别是2.84±2.84和6.27±3.94、3.23±2.92和6.68±4.53;与无复发或未死亡患者相比,复发和死亡患者的survivin IDS明显增高(均P<0.001)。与survivin IDS 0~4组相比,IDS 6~12组患者的复发和死亡风险分别增高12倍和3倍,且无复发生存期和生存期均明显缩短(P<0.005-0.001)。结论 Survivin在脑膜瘤的发生、发展中发挥了重要作用,可作为预测脑膜瘤不良预后的有效指标。 展开更多
关键词 SURVIVIN 脑膜瘤 无复发生存期 生存期 浓度评分
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Production and Evaluaton of Yoghurt Flavoured with Beetroot (Beta vulgaris L,)
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作者 Mbaeyi-Nwaoha Ifeoma Elizabeth Nwachukwu Godstar Onyinyechi 《Journal of Food Science and Engineering》 2012年第10期583-592,共10页
Beetroot (Beta vulgaris L.) was pulped to get the juice. The juice was given heat treatment. Yoghurt was formulated and flavored with prepared beetroot (Beta vulgaris L.) juice at different concentration levels (... Beetroot (Beta vulgaris L.) was pulped to get the juice. The juice was given heat treatment. Yoghurt was formulated and flavored with prepared beetroot (Beta vulgaris L.) juice at different concentration levels (0, 10, 20, 30, 40 and 50 mL). The most preferred flavored yoghurt samples were obtained by sensory scores (color, flavor, mouth feel, aftertaste and overall acceptability). The most preferred sample was then subjected to proximate, physico-chemical, microbiological and micro-nutrient analysis. The result obtained showed that the pH value ranged between 6.5 and 7.8. Thus, this showed that the product was quite good. However, ash and moisture content increased with addition of the beetroot juice, while micro-nutrient, (Mg, Na, K, Ca and Vitamin C) increased with the addition of the juice. There was no significant difference (P 〉 0.05) in the overall acceptability of all products. There was no coliform and mould growth in all the samples. The best concentration level in the samples was 90 mL of yoghurt and 10 mL of beetroot juice. Therefore, the beetroot flavored yoghurt could be said to be nutritious, safe and an acceptable product by the panelists. 展开更多
关键词 Beetroot YOGHURT sensory properties micronutrients.
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Evaluation of Metal Contamination of Mullet (Mullus surmuletus L., 1758) in the Bay of Oran
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作者 Borsali Sofia Bouderbala Mohamed Boutiba Zitouni 《Journal of Life Sciences》 2014年第4期344-350,共7页
The present study focused on the evaluation of the contamination by three heavy metals (Cd, Cu and Zn) of a bony fish, Mullus surmuletus L., 1758, caught in the Bay of Oran. This reflects the quality of fish habitat... The present study focused on the evaluation of the contamination by three heavy metals (Cd, Cu and Zn) of a bony fish, Mullus surmuletus L., 1758, caught in the Bay of Oran. This reflects the quality of fish habitat as species common Algerian coastal waters and enjoyed by a large fish-eating population. Monthly sampling was spread over a period of six months (December 2011-May 2012). Given their physiological importance in the body, muscle, liver and gonads were targeted. Metal concentrations were determined by atomic absorption spectrophotometry in flame depends on three parameters (sex, size and month). It appears from this study that the target organs of rouget (M. surmuletus) accumulate three metal pollutants sought. The highest values are those of zinc, copper and cadmium are at concentrations at least important. The results, statistically treated, showed no significant difference between the concentrations of trace metals both sexes and at all three organs considered. The average dose of heavy metals found in the mullet compared to those provided by the literature relating to DMA (Maximum Allowable Doses), are not worrisome. Concentration levels of toxic metals reflect a certain metal pollution in the Bay of Oran. 展开更多
关键词 Rouget Mullus surmuletus heavy metals (Cd Cu Zn) concentration CONTAMINATION DMA Oran Bay Mediterranean.
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