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鸡新城疫消化道免疫的研究 Ⅱ、幼雏消化道免疫组织化学及功能研究 被引量:5
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作者 朱晓平 王树信 《畜牧兽医学报》 CAS CSCD 北大核心 1989年第2期187-192,共6页
本实验采用免疫组织化学方法及酶联免疫吸附试验(ELISA)对鸡新城疫弱毒活苗消化道直接免疫后,对其免疫机制和免疫效果进行了研究。 7日龄前,雏鸡肠道无免疫球蛋白G阳性细胞出现。7日龄后出现并缓慢上升,第二次免疫(嗉囊免疫、饮水免疫)... 本实验采用免疫组织化学方法及酶联免疫吸附试验(ELISA)对鸡新城疫弱毒活苗消化道直接免疫后,对其免疫机制和免疫效果进行了研究。 7日龄前,雏鸡肠道无免疫球蛋白G阳性细胞出现。7日龄后出现并缓慢上升,第二次免疫(嗉囊免疫、饮水免疫)后增长明显,出现峰值。免疫组与对照组差异显著,表明雏鸡胃肠道具有保持产生局部抗体的功能,并且血清IgG抗体效价的消长与之呈现相关免疫状态。胃肠道T淋巴细胞在第一次免疫(嗉囊免疫、饮水免疫)后10天和二免后5~10天出现峰值,然后下降并稳定在一定水平,证明细胞免疫参与鸡新城疫消化道免疫。 展开更多
关键词 鸡新城疫 消化道免疫 机制
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消化道免疫与消化系疾病
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作者 潘伯荣 张学庸 《临床内科杂志》 CAS 1989年第2期9-11,共3页
消化系统有丰富的免疫组织,在免疫功能的建立过程中胃肠道所起的作用,以及免疫障碍在一些胃肠系统疾病的发病机理中都有重要意义.众所周知脾脏是最大的淋巴器官,是体内抗体产生的主要场所.肝内Kupffer细胞也有重要作用.
关键词 消化道免疫 消化系病 免疫障碍
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鸡新城疫消化道免疫的研究——Ⅲ、ELISA和HI试验检测抗体的比较 被引量:2
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作者 朱晓平 王树信 《中国兽医杂志》 CAS 北大核心 1991年第1期9-12,共4页
对养禽业来说,检测鸡群群体免疫水平是非常重要的。酶联免疫吸附试验(ELISA)已广泛应用于检测多种禽病抗体和抗原。本法具有敏感、特异、易实现自动化等特点(Nicholas,1986)。ELISA在检测鸡新城疫的抗体方面已取得成功(Mier,1983;Snyder... 对养禽业来说,检测鸡群群体免疫水平是非常重要的。酶联免疫吸附试验(ELISA)已广泛应用于检测多种禽病抗体和抗原。本法具有敏感、特异、易实现自动化等特点(Nicholas,1986)。ELISA在检测鸡新城疫的抗体方面已取得成功(Mier,1983;Snyder 1983、1984;Marquardt,1984)。而国内报道尚少。消化道免疫作为鸡新城疫群体免疫的最常用方法之一,在生产中已得到了广泛应用。为此本实验利用ELISA和HI试验比较检测了鸡新城疫消化道免疫后,雏鸡抗体的消长规律。 展开更多
关键词 新城疫 消化道免疫 ELISA 抗体
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家禽免疫应答机理及消化道免疫力 被引量:1
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作者 D.R.Korver 徐仕忠 《中国家禽》 北大核心 2010年第14期41-46,共6页
健康与疾病控制贯穿家禽生产管理的全过程,了解家禽免疫应答的的作用机理,能有效帮助我们理解疫病发生和疫苗接种的机理。本文详细介绍了家禽天然免疫应答和获得性免疫应答的作用机理以及与免疫应答相关的细胞和化学介质的功能与作用途... 健康与疾病控制贯穿家禽生产管理的全过程,了解家禽免疫应答的的作用机理,能有效帮助我们理解疫病发生和疫苗接种的机理。本文详细介绍了家禽天然免疫应答和获得性免疫应答的作用机理以及与免疫应答相关的细胞和化学介质的功能与作用途径,并介绍消化道内免疫系统的分布和功能。 展开更多
关键词 家禽 天然免疫 获得性免疫 消化道免疫
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Risk of postoperative recurrence and postoperative management of Crohn's disease 被引量:4
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作者 Antonino Spinelli Matteo Sacchi +2 位作者 Gionata Fiorino Silvio Danese Marco Montorsi 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第27期3213-3219,共7页
Crohn's disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority ... Crohn's disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority of CD patients require surgery during their lifetime due to progressive bowel damage, but, even when all macroscopic lesions have been removed by surgery, the disease recurs in most cases. Postoperative management represents therefore a crucial mean for preventing recurrence. Several drugs and approaches have been proposed to achieve this aim. Endoscopic inspection of the ileocolic anastomosis within 1 year from surgery is widely encouraged, given that endoscopic recurrence is one of the greatest predictors for clinical recurrence. A strategy should be planned only after stratifying patients according to their individual risk of recurrence, avoiding unnecessary therapies when possible benefits are reduced, and selecting high-risk patients for more aggressive intervention. 展开更多
关键词 Crohn’s disease RECURRENCE Postoperative treatment SURGERY SURVEILLANCE
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Association between Helicobacter pylori seropositivity and digestive tract cancers 被引量:8
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作者 I-Chen Wu Deng-Chyang Wu +5 位作者 Fang-Jung Yu Jaw-Yuan Wang Chao-Hung Kuo Sheau-Fang Yang Chao-Ling wang Ming-Tsang Wu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第43期5465-5471,共7页
AIM: To explore the role of Helicobacter pylori (Hpylori) infection on the risk of digestive tract cancers. METHODS: In total, 199 oral squamous-cell carcinoma (SCC), 317 esophagea! SCC, 196 gastric cardia and n... AIM: To explore the role of Helicobacter pylori (Hpylori) infection on the risk of digestive tract cancers. METHODS: In total, 199 oral squamous-cell carcinoma (SCC), 317 esophagea! SCC, 196 gastric cardia and non-cardia adenocarcinoma and 240 colon adenocarcinoma patients were recruited for serum tests of Hpylori infection. Two hospital- and one community-based control groups were used for the comparisons. Hpylori seropositivity was determined by an enzyme linked immunosorbent assay method against Hpylori IgG. RESULTS: Presence of H pylori infection was significantly inversely associated with esophageal SCC [adjusted odds ratio (AOR): 0.315-0.472, all P-value 〈 0.05] but positively associated with gastric adenocarcinoma (both cardia and non-cardia) (AOR: 1.636-3.060, all P-value 〈 0.05) in comparison to the three control groups. Similar results were not found in cancers of the oral cavity and colon. CONCLUSION: Our findings support the finding that H pylori seropositivity is inversely associated with esophageal SCC risk, but increases the risk of gastric cardia adenocarcinoma. 展开更多
关键词 Helicobacter pylori infection Oral cancer Esophageal squamous cell carcinoma Gastric cardia adenocarcinoma Colon cancer
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