注射用泮托拉唑、去甲肾上腺素、注射用白眉蛇毒凝血酶联用治疗饮酒后上消化道出血64例临床分析

目的探讨联合注射用泮托拉唑、去甲肾上腺素及白眉蛇毒凝血酶治疗饮酒后上消化道出血的临床疗效。方法选择临床确诊饮酒后上消化道出血患者64例,将其随机分为对照组和治疗组,每组32例。治疗组32例给予泮托拉唑、去甲肾上腺素、白眉蛇毒凝血酶联合使用;对照组32例给予注射用泮托拉唑、氨甲苯酸联合使用。两组保护胃粘膜及补液等治疗方案相同,比较两组治疗效果。结果治疗组总有效率87.5%,明显优于对照组总有效率62.5%,组间比较差异有统计学意义(P<0.05);治疗组平均显效时间明显短于对照组,组间差异有统计学意义(P<0.05);治疗期间,两组出现恶心不良反应症状,经对症处理后症状消失。结论饮酒后上消化道出血患者,采用泮托拉唑、去甲肾上腺素、注射用白眉蛇毒凝血酶联用治疗的疗效确切,而且安全性高、不良反应少,值得临床应用。

清开灵注射液合甘露消毒饮治疗湿温高热33例

清开灵注射液合甘露消毒饮治疗湿温高热３３例黄可成陈寿菲蔡学熙用清开灵配合甘露消毒饮（丸）治疗湿温高热３３例取得较好效果，报告如下。１病例与方法１．１病例选择：凡符合下列条件者作为选择对象：较典型的湿热病证患者，壮热稽留或日晡热盛（３９．０℃左右），身...

Effects of the Dietary Probiotic Clostridium butyricum on Intestine Digestive and Metabolic Capacities, SCFA Content and Body Composition in Marsupenaeus japonicus

A 56-day feeding trial was performed to evaluate the effects of dietary probiotic Clostridium butyricum(CB) on intestine digestive and metabolic capacities, intestine short-chain fatty acids(SCFA) content and body composition of kuruma shrimp Marsupenaeus japonicus. Shrimp s were randomly allocated into 9 tanks, 30 each, and f ed with diets containing different levels of C. butyricum(1×10~9 cfug^(-1)): 0 mgg^(-1) feed(Control), 100 mgg^(-1) feed(CB-100), 200 mgg^(-1) feed(CB-200), while each level was triplicated. The results indicated that compared with the control group, the intestine pepsin(Pep) activity and 5-hydroxytryptamine(5-HT) concentration of two C. butyricum group s were both increased. Amylase(AM Y) and lipase(LPS) activities wer e only induced in CB-200 group. Alanine aminotransferase(ALT) and aspartate aminotransferase(A ST) activities of two C. butyricum group s showed no significant change. The α-amylase(AM Y) gene expression was induced in CB-200 group, and tryp sin gene expression of two C. butyricum treated group s were both induced. Intestine SCFA content and body composition analysis showed that the contents of propionic acid, butyric acid and the crude protein of two C. butyricum group s were all higher than those of control. These results revealed that C. butyricum can modulate intestine digestive and metabolic capacities, improve intestine SCFA content and body crude protein content in M. japonicus.

Satiety testing: Ready for the clinic?

Drink tests are advocated as an inexpensive, nonivasive technique to assess gastric function in patients with a variety of upper digestive symptoms. Many patients with dyspeptic complaints will achieve satiation or develop symptoms at ingested volumes below those typically required to achieve these endpoints in controls. Substantial variation in test performance exists and a greater degree of standardization is required. Additionally, it remains unclear exactly what drink tests measure as correlations with measures of gastric sensation, accomodation and emptying are modest at best. Finally, results of drink tests do not guide therpay. At present, these tests are best reserved for research studies and are not advocated for use in clinical practice.

Effect of High Digestible Essential Amino Acids on Weight Gains and Carcass Compositions of Laying Hens

The objective of this study was to evaluate the effect of high digestible essential amino acids （DEAA） on weight gains and carcass compositions of laying hens. Three hundred and sixty lsa Brown hens in five replications per treatment （12 birds/replicate） were used. Six experimental diets which contained of treatment 1 （negative control） as the conventional layer diet are recommended by NRC （1994） while another dietary treatments; treatments 2 （positive control）, 3, 4, 5 and 6 were formulated to meet 100%, 110%, 120%, 130% and 140% of Standard Ileal Digestible Lysine Levels （SIDLL） without crude protein minimum, while methionine （Met）, threonine （Thre） and tryptophan （Tryp） as related by Ideal Protein Concept （IPC） which suggested by NRC （1994） and INRA （2004）. However, metabolizable energy （ME）, calcium and available phosphorus （Avai P） levels of all experimental diets were meet requirement as recommended by NRC （1994）. The experiment was assigned in CRD and laying hens fed dietary treatments from 28 to 44 weeks of age and cage was the experimental unit （3 hens/cage）. The result shown that percentages of thigh （TP）, feet （FP）, drumstick （DP）, heart （HP）, liver （LP） and gizzard （GP） were not affected by dietary treatment. However, weight gains （WG） and percentage of dressed weight （DWP）, eviscerate weight （EWP） and breast （BP） were increased （P 〈 0.05） and abdominal fat was reduced （P 〈 0.05） when birds fad diets containing 130% of SIDLL as compared with control group and another dietary treatments, when increasing the DEAA levels upper to 130% of SIDLL. The result indicated that diets formulated without crude protein minimum and increased DEAA resulted in increasing the efficiency of converting metabolizable energy （ME） to net energy （NE） for increasing weight gain and improved meat products while fat deposition in carcass composition was reduced.

Prevalence of functional dyspepsia and its subgroups in patients with eating disorders

AIM:To study the prevalence of functional dyspepsia(FD)(Rome Ⅲ criteria) across eating disorders(ED),obese patients,constitutional thinner and healthy volunteers.METHODS:Twenty patients affected by anorexia nervosa,6 affected by bulimia nervosa,10 affected by ED not otherwise specified according to diagnostic and statistical manual of mental disorders,4th edition,nine constitutional thinner subjects and,thirtytwo obese patients were recruited from an outpatients clinic devoted to eating behavior disorders.Twentytwo healthy volunteers matched for age and gender were enrolled as healthy controls.All participants underwent a careful clinical examination.Demographic and anthropometric characteristics were obtained from a structured questionnaires.The presence of FD and,its subgroups,epigastric pain syndrome and postprandial distress syndrome(PDS) were diagnosed according to Rome Ⅲ criteria.The intensity-frequency score of broader dyspeptic symptoms such as early satiety,epigastric fullness,epigastric pain,epigastric burning,epigastric pressure,belching,nausea and vomiting were studied by a standardized questionnaire(0-6).Analysis of variance and post-hoc Sheffè tests were used for comparisons.RESULTS:90% of patients affected by anorexia nervosa,83.3% of patients affected by bulimia nervosa,90% of patients affected by ED not otherwise specified,55.6% of constitutionally thin subjects and 18.2% healthy volunteers met the Postprandial Distress Syndrome Criteria(χ 2,P < 0.001).Only one bulimic patient met the epigastric pain syndrome diagnosis.Postprandial fullness intensity-frequency score was significantly higher in anorexia nervosa,bulimia nervosa and ED not otherwise specified groups compared to the score calculated in the constitutional thinner group(4.15 ± 2.08 vs 1.44 ± 2.35,P = 0.003;5.00 ± 2.45vs 1.44 ± 2.35,P = 0.003;4.10 ± 2.23vs 1.44 ± 2.35,P = 0.002,respectively),the obese group(4.15 ± 2.08vs 0.00 ± 0.00,P < 0.001;5.00 ± 2.45vs 0.00 ± 0.00,P < 0.001;4.10 ± 2.23 vs 0.00 ± 0.00,P < 0.001,respectively) and healthy volunteers(4.15 ± 2.08 vs 0.36 ± 0.79,P < 0.001;5.00 ± 2.45 vs 0.36 ± 0.79,P < 0.001;4.10 ± 2.23 vs 0.36 ± 0.79,P < 0.001,respectively).Early satiety intensity-frequency score was prominent in anorectic patients compared to bulimic patients(3.85 ± 2.23 vs 1.17 ± 1.83,P = 0.015),obese patients(3.85 ± 2.23 vs 0.00 ± 0.00,P < 0.001) and healthy volunteers(3.85 ± 2.23 vs 0.05 ± 0.21,P < 0.001).Nausea and epigastric pressure were increased in bulimic and ED not otherwise specified patients.Specifically,nausea intensity-frequencyscore was significantly higher in bulimia nervosa and ED not otherwise specified patients compared to anorectic patients(3.17 ± 2.56 vs 0.89 ± 1.66,P = 0.04;2.70 ± 2.91 vs 0.89 ± 1.66,P = 0.05,respectively),constitutional thinner subjects(3.17 ± 2.56 vs 0.00 ± 0.00,P = 0.004;2.70 ± 2.91 vs 0.00 ± 0.00,P = 0.005,respectively),obese patients(3.17 ± 2.56 vs 0.00 ± 0.00,P < 0.001;3.17 ± 2.56 vs 0.00 ± 0.00,P < 0.001 respectively) and,healthy volunteers(3.17 ± 2.56 vs 0.17 ± 0.71,P = 0.002;3.17 ± 2.56 vs 0.17 ± 0.71,P = 0.001,respectively).Epigastric pressure intensityfrequency score was significantly higher in bulimic and ED not otherwise specified patients compared to constitutional thin subjects(4.67 ± 2.42 vs 1.22 ± 1.72,P = 0.03;4.20 ± 2.21 vs 1.22 ± 1.72,P = 0.03,respectively),obese patients(4.67 ± 2.42 vs 0.75 ± 1.32,P = 0.001;4.20 ± 2.21vs 0.75 ± 1.32,P < 0.001,respectively) and,healthy volunteers(4.67 ± 2.42 vs 0.67 ± 1.46,P = 0.001;4.20 ± 2.21vs 0.67 ± 1.46,P = 0.001,respectively).Vomiting was referred in 100% of bulimia nervosa patients,in 20% of ED not otherwise specified patients,in 15% of anorexia nervosa patients,in 22% of constitutional thinner subjects,and,in 5.6% healthy volunteers(χ 2,P < 0.001).CONCLUSION:PDS is common in eating disorders.Is it mandatory in outpatient gastroenterological clinics to investigate eating disorders in patients with PDS?

Selection of diet for culture of juvenile silver pomfret, Pampus argenteus

Juvenile silver pomfret, Pampus argenteus, was grown in culture tanks for 9 weeks on four different diets, and their effects on fish growth, digestive enzyme activity, and body composition were assessed. The feeding regime was as follows: Diet 1: fish meat; Diet 2: fish meat+artificial feed; Diet 3: fish meat+artificial feed+Agamaki clam meat; Diet 4: fish meat+artificial feed+Agamaki clam+copepods. The greatest weight gain was associated with Diet 4, while the lowest weight gain was associated with Diet 1. No significant difference was observed in weight gain between fish receiving Diet 2 and Diet 3. Specific growth rate followed similar trends as weight gain. The feed conversion ratio (FCR) of fish fed Diet 1 was significantly higher than the other fish groups, but no significant differences were observed in FCRs of fish fed Diet 2, Diet 3 or Diet 4. There was also no significant difference in the hepatosomatic index (HSI) between the four diets. For fish that received Diets 2-4, containing artificial feed, higher protease activities were detected. A higher lipid content of the experimental diets also significantly increased lipase activities and body lipid content. No significant differences in amylase activity or body protein content were found between Diets 1-4. In conclusion, a variety of food components, including copepods and artificial feed, in the diet of silver pomfret significantly increased digestive enzyme activity and could improve growth performance.

Impacts of High Fiber Diet on Digestion and Absorption of Minerals in Growing Pigs

The study was conducted to investigate the effects of feeding high-fiber diet （HFD） on apparent total tract digestibility （ATTD） and absorption of minerals in growing pigs. Sixteen barrows averaging 16.39 kg were randomly assigned to one of four diets after metabolic crate assignment with individual pig serving as experimental unit. Diets include： a corn-soybean meal based low-fiber diet （LFD）, as the control （CON） and 3 HFD （D1, D2 and D3）, each containing 5% sugar beet pulps and a 1：2, 1：1 and 2：1 oats to barley ratios, respectively, replacing 47% of the corn in the diet. Diets were formulated to meet nutrient requirements, however, the fiber content of the LFD was substantially lower than the average of the HFD （8.38% vs. 22.40%）. Feed allowance was limited to 10% of average body weight and fed twice/d. The study period was divided into 10 d of adjustment and 5 d of feces collection. Data collected were analyzed using SAS, GLIMMIX procedure where animals were considered random effects, and minerals were fixed. Results of the study show that digestibility of Ca in pigs fed HFD was lower （P 〈 0.05） than in pigs fed LFD. On the other hand, the apparent digestibility of P, K, Na, S and Zn in pigs fed D2 and D3 were higher （P 〈 0.05） than in pigs fed CON diet. It was also observed that digestibility of Ca, P, K, Na, S and Zn in pigs fed D1 were lower （P 〈 0.05） than in CON, D2 or D3 fed pigs. Therefore, it was concluded that while feeding HFD reduced availability of Ca, the availability of P, K, Na and S to pigs improved as the oat to barley ratio in the diet increased.

Leucaena leucocephala Meal as Replacement to Soybean Meal in Growing Goat Diets

Eight goats of 7-8 months old and an average body weight （BW） of 20 ± 5.0 kg were used in double 4 × 4 Latin square design. The treatments were the four levels of leucaena meal replacement for soybean meal in concentrates at 0%, 25%, 50% and 75% of crude protein. The results showed that roughage intake （% BW and g/kgBW^0.75） increased linearly （P 〈 0.01） with increasing levels of leucaena meal while total feed intake was not significantly different among dietary treatments. Similarly, dry matter, organic matter, neutral detergent fiber digestibility and ruminal ammonia nitrogen （NH3-N） were not significantly different among dietary treatments. However, crude protein digestibility, ruminal pH （6 hr after feeding）, nitrogen （N） intake, N absorption, N retention and total volatile fatty acids increased quadratically （P 〈 0.01） with the increasing levels of leucaena meals. It could be concluded that leucaena meal could replace up to 50% of soybean meal in the diet without any negative effect on feed intake, nutrient digestibility and rumen fermentation of meat goats.

The Effect of Supplementation of Gliricidia or Rice Bran on Feed Intake, Digestibility and Liveweight Gain of Kacang Goat Fed Mulato Grass

A low liveweight gain of of Kacang goats when given grass as single feed indicated that additional feed is required to increase their gowth performance. This study was done to examine the effect of addition of Gliricidia （Gliricidia sepium） leaf or rice bran on feed intake, feed digestibility and liveweight gain of Kacang goat given Mulato （Brachiaria mulato） grass. Twenty four male Kacang goat, approximately 13.4±0.6 kg in initial weight and 10 months of age, were housed in individual metabolic pen and allocated to one of three dietary treatments. The experimental design was a completely randomized block design, with three treatments and eight replicates （goats）. The treatments were Mulato grass ad libitum （M）, Mulato ＋ Gliricidia （1% weight/d on dry matter basis） （MG）, and Mulato ＋ rice bran （1% weight/d on dry matter basis） （MR）. The experiment was run for eight weeks period （two weeks for adaptation and and six weeks for measurement period, respectively）. Parameters measured were liveweight gain （LWG）, dry matter intake （DMI） and dry matter digestibility （DMD）. The result showed that dietary treatment significantly （P 〈 0.05） affected the LWG, DMI and DMD of Kacang goat. Goat given Mulato grass had the lowest LWG, DMI and DMD with value 58 g/d, 2.77% weight/d and 57.61%, respectively. Goat received Mulato ＋ Gliricidia and Mulato ＋ rice bran had a significant higher LWG （73 g/d and 76 g/d, respectively）, DMI （3.25% weight/d and 3.65% weight/d, respectively） and DMD （62.28% and 63.19%, respectively）. However, no significant difference （P 〉 0.05） between goat received Mulato ＋ Gliricidia and Mulato ＋ rice bran. In conclusion, this study demonstrated that protein or energy contents of the diet influenced growth, feed intake and digestibility of Kacang goat.

叩齿刷牙保健康

牙齿是人体消化饮食物的第一关,齿健则能充分咀嚼食物,帮助脾胃消化,有利于营养物质的吸收。牙齿的健康情况直接影响到身体的健康情况。那么如何做才能保持牙齿健康呢？这里介绍两种方法,即叩齿和洗刷。