疏肝消郁散联合西药治疗老年中风后抑郁44例

目的:观察疏肝消郁散联合西药治疗老年中风后抑郁的临床疗效。方法:选取2012年6月—2014年12月老年中风后轻中度抑郁症患者88例,随机分为对照组和治疗组,每组44例。对照组给予盐酸帕罗西汀片口服治疗,治疗组在对照组的基础上加用舒肝消郁散治疗。结果:治疗组有效率为91.0%,对照组有效率为78.0%,治疗组优于对照组(P<0.05);治疗组治疗后SDS评分、barthel指数、LSIA评分优于对照组,差异有统计学意义(P<0.05);两组不良反应比较,治疗组明显低于对照组(P<0.05)。结论:疏肝消郁散联合西药治疗老年中风后抑郁效果显著。

自制消郁散贴敷结合药物治疗乳腺增生的应用效果

为探讨自制消郁散穴位贴敷结合药物治疗对乳腺增生的临床疗效。方法 回顾性分析广西中医药大学第一附属医院2021年1月至2023年1月间收治的116例乳腺增生患者临床资料,将其随机分为治疗组和对照组,每组58例。对照组采用传统药物疗法进行治疗,治疗组采用自制消郁散穴位贴敷结合药物治疗。结果 两组治疗后,综合疗效总有效率治疗组为93.10%,对照组为81.03%,且两组治疗前后组内比较及治疗后组间比较,差异均有统计学意义。结论 自制消郁散穴位贴敷结合药物治疗乳腺增生疗效显著,具有独特的优势和潜力,值得临床推广以及应用。

Rupi Sanjie Xiaotong Plaster in Treating Breast Hyperplasia of Liver Stagnation and Phlegm Coagulation Pattern

Objective:To observe the clinical efcacy and safety of external application of Rupi Sanjie Xiaotong Plaster(乳癖散结消痛膏,RPSJXTP)in treating breast hyperplasia of liver stagnation and phlegm coagulation pattern.Methods:Totally 72 female patients with breast hyperplasia of liver stagnation and phlegm coagulation pattern admitted to the First Hospital Affiliated to Henan University of Chinese Medicine were enrolled by ran-domized,single-blind,placebo-controlled research method,and were divided into the treatment group(36 ca-ses)and the control group(36 cases)according to computer random number method.The treatment group were given RPSJXTP,while the control group were gi ven placebo plaster.The course of treatment in both groups was 8 weeks.The breast pain score,breast color ultrasound score,lump score,depression score,and Chinese medicine syndrome score were compared between the two groups at different times.The levels of estra-diol(E_(2)),progesterone(P)and pituitary prolactin(PRL)were detected and the adverse reactions of two groups were observed during the treatment of both groups.Results:Before treatment,there was no significant difference in total breast pain score,breast color ultrasound score,lump score,depression score and levels of serum P,E_(2)and PRL between the two groups(P>0.05);compared with previous treatment,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased in the treat-ment group(P<0.05),and the total breast pain score and depression score of the control group significantly declined(P<0.05);compared with control group,the total breast pain score,breast color ultrasound score,lump score,and depression score significantly decreased after treatment in the treatment group(P<0.05).The improvement rate of Chinese medicine syndromes and the clinical efective rate in the treatment group were higher than those in the control group(P<0.05).There were no serious systemie adverse reactions during the treatment in both groups.Local pruritus occurred in 3 cases in the treatment group and 1 case in the control group.Conclusion:RPSJXTP is effective in treating breast hyperplasia of liver stagnation and phlegm coagula-tion pattern.It can effectively relieve the breast pain which will not recur after stopping of drug use,which can reduce the color ultrasound score,lump score,and depression score of the patients and improve Chinese medi-cine syndromes without serious adverse reactions.