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HPLC法测定琥乙红霉素口服制剂中红霉素残留量 被引量:3
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作者 佟志 钟长鸣 王庆全 《药品评价》 CAS 2005年第6期434-435,共2页
目的建立琥乙红霉素口服制剂中红霉素残留量的检测方法。方法采用HamilT&NRP-1 L21(250mm×4.6mm)色譜柱,柱温:60℃,磷酸盐缓冲液(0.067mol.L-1,pH9.0)―乙晴―叔丁醇―水(453∶51∶28∶)为流动相,流速:0.8ml.min-1,检测波长:21... 目的建立琥乙红霉素口服制剂中红霉素残留量的检测方法。方法采用HamilT&NRP-1 L21(250mm×4.6mm)色譜柱,柱温:60℃,磷酸盐缓冲液(0.067mol.L-1,pH9.0)―乙晴―叔丁醇―水(453∶51∶28∶)为流动相,流速:0.8ml.min-1,检测波长:215nm,进样量:100μL。结果红霉素在300u.ml-1~3000u.ml-1范围内呈良好线性关系(r=0.9995),平均回收率为103.7%,RSD为1.1%,最低检测限为1.5u。结论该法专属性强,灵敏度高,重现性较好,可作为琥乙红霉素口服制剂中红霉素残留量的测定方法。 展开更多
关键词 琥乙红霉素 红霉素残留色谱法 高效液相
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谈降低混凝土坍落度损失的几项措施 被引量:4
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作者 于华东 李兆肇 徐雪峰 《能源技术与管理》 2005年第4期65-66,共2页
混凝土拌合物初期的流动性极好,但随着时间的增加,水泥粒子在水泥—水体系中不断发生水化反应,由此产生的化学凝聚和物理凝聚使混凝土的流动性逐渐变小,坍落度损失就越来越大,适量掺入外加剂能改善混凝土的和易性。
关键词 坍落度 减水剂 缓凝剂 引气剂 流化剂 缩合度 液相残留量
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Determination of Tetracycline and Oxytetracycline Residues in Honey by High Performance Liquid Chromatography 被引量:1
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作者 Shaif Mohammed Kasem Saleh Amer Mohammed Mussaed Fadhl Mohammed Al-Hariri 《Journal of Agricultural Science and Technology(B)》 2016年第2期135-139,共5页
Honey is being used as a pure natural and as an ingredient in many foods, pharmaceuticals and cosmetics than ever before, so honey testing has become essential to maintain its healthful characteristics and protect pub... Honey is being used as a pure natural and as an ingredient in many foods, pharmaceuticals and cosmetics than ever before, so honey testing has become essential to maintain its healthful characteristics and protect public health. Tetracyclines (TCs) are used for the treatment or prevention of American and European foul broad in bee colonies which are caused especially by two species of bacteria--Paenibacillus larvae and Melissococcus pluton. The present study aimed to determine the tetracycline residues in different types of local and imported honey. The reversed-phase high performance liquid chromatography (HPLC) with ultraviolet detection (UV) was used. Tetracycline and oxytetracycline were extracted from honey with 0.01 M sodium succinate buffer. Of the examined samples, 31.25% and 12.50% had these oxytetracycline and tetracycline residues, respectively. It was observed that all the samples studied have been reported residues of tetracycline and oxytetracycline more than international standards of maximum residue limit (MRLs). 展开更多
关键词 HONEY antibiotic residues TETRACYCLINE OXYTETRACYCLINE HPLC Yemen.
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