Contrast agents are increasingly being used to characterize the vasculature in an organ of interest,to better delineate benign from malignant pathology and to aid in staging and directing therapeutic procedures.We rev...Contrast agents are increasingly being used to characterize the vasculature in an organ of interest,to better delineate benign from malignant pathology and to aid in staging and directing therapeutic procedures.We review the mechanisms of action of first,second and third generation contrast agents and their use in various endoscopic procedures in the gastrointestinal tract.Various applications of contrast-enhanced endoscopic ultrasonography include differentiating benign from malignant mediastinal lymphadenopathy,assessment of depth of invasion of esophageal,gastric and gall bladder cancers and visualization of the portal venous system and esophageal varices.In addition,contrast agents can be used to differentiate pancreatic lesions.The use of color Doppler further increases the ability to diagnose and differentiate various pancreatic malignancies.The sensitivity of power Doppler sonography to depict tumor neovascularization can be increased by contrast agents.Contrast-enhanced harmonic imaging is a useful aid in identifying the tumor vasculature and studying pancreatic microperfusion.In the future,these techniques could potentially be used to quantify tumor perfusion,to assess and monitor the efficacy of antiangiogenic agents,to assist targeted drug delivery and allow molecular imaging.展开更多
Objective.To improve the clinical knowledge of lymphangiomatosis.Methods.We pre sented a case of a30?year?old woman where generalized lymphangiomatosis pre-sented with an inguinal mass.Multiple imaging modalities were...Objective.To improve the clinical knowledge of lymphangiomatosis.Methods.We pre sented a case of a30?year?old woman where generalized lymphangiomatosis pre-sented with an inguinal mass.Multiple imaging modalities were undertaken,inc luding plain film,CT,MRI ,US,and lymphangiography.Splenectomy was performe d.Results.The bones,lungs,spleen and retroperitoneal lymphatics were involve d.The diagnosis was made by integration of clinical,imaging and pathological f indings.Also a literature review regarding clin-ical presentation,diagnosis, management and outcome of this rare disease was made.Conclusion.we suggest the importance of clinical knowledge of the entity and imaging procedures are es sential for better diagnosis,thus avoiding more invasive procedures.展开更多
文摘Contrast agents are increasingly being used to characterize the vasculature in an organ of interest,to better delineate benign from malignant pathology and to aid in staging and directing therapeutic procedures.We review the mechanisms of action of first,second and third generation contrast agents and their use in various endoscopic procedures in the gastrointestinal tract.Various applications of contrast-enhanced endoscopic ultrasonography include differentiating benign from malignant mediastinal lymphadenopathy,assessment of depth of invasion of esophageal,gastric and gall bladder cancers and visualization of the portal venous system and esophageal varices.In addition,contrast agents can be used to differentiate pancreatic lesions.The use of color Doppler further increases the ability to diagnose and differentiate various pancreatic malignancies.The sensitivity of power Doppler sonography to depict tumor neovascularization can be increased by contrast agents.Contrast-enhanced harmonic imaging is a useful aid in identifying the tumor vasculature and studying pancreatic microperfusion.In the future,these techniques could potentially be used to quantify tumor perfusion,to assess and monitor the efficacy of antiangiogenic agents,to assist targeted drug delivery and allow molecular imaging.
文摘Objective.To improve the clinical knowledge of lymphangiomatosis.Methods.We pre sented a case of a30?year?old woman where generalized lymphangiomatosis pre-sented with an inguinal mass.Multiple imaging modalities were undertaken,inc luding plain film,CT,MRI ,US,and lymphangiography.Splenectomy was performe d.Results.The bones,lungs,spleen and retroperitoneal lymphatics were involve d.The diagnosis was made by integration of clinical,imaging and pathological f indings.Also a literature review regarding clin-ical presentation,diagnosis, management and outcome of this rare disease was made.Conclusion.we suggest the importance of clinical knowledge of the entity and imaging procedures are es sential for better diagnosis,thus avoiding more invasive procedures.
