短暂性头痛和神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache and neu-rological deficits with cerebrospinal fluid lymphocyto-sis,HaNDL)以短暂的神经功能缺损和偏头痛样头痛发作为主要临床表现,伴脑脊液...短暂性头痛和神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache and neu-rological deficits with cerebrospinal fluid lymphocyto-sis,HaNDL)以短暂的神经功能缺损和偏头痛样头痛发作为主要临床表现,伴脑脊液淋巴细胞增多,一般3个月内自发缓解,是一种自限性疾病[1]。展开更多
短暂头痛、神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache andneurolo-gical deficits with cerebrospinal fluid lymphocytosis,HaNDL)主要表现为发作性头痛伴有短暂性神经功能缺损,实验室检查可发现脑脊液...短暂头痛、神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache andneurolo-gical deficits with cerebrospinal fluid lymphocytosis,HaNDL)主要表现为发作性头痛伴有短暂性神经功能缺损,实验室检查可发现脑脊液淋巴细胞增多,可呈反复发作病程。国内鲜有报道,可能是因为HaNDL综合征易与病毒性脑炎、短暂性脑缺血发作等疾病混淆,其次考虑与认知不足有关。为提高对此综合征的认识,本文就其病因、临床特征、诊断标准、鉴别诊断及治疗方面的进展进行了综述。展开更多
慢性自然杀伤（naturekiller,NK）细胞起源于骨髓造血干细胞,呈大颗粒细胞形态,约占外周血淋巴细胞的5%,主要参与机体的非特异免疫。慢性NK细胞淋巴细胞增多症（chronic NK cell lymphocytosis,CNKL）是一组罕见的异质性疾病,该病病因不...慢性自然杀伤（naturekiller,NK）细胞起源于骨髓造血干细胞,呈大颗粒细胞形态,约占外周血淋巴细胞的5%,主要参与机体的非特异免疫。慢性NK细胞淋巴细胞增多症（chronic NK cell lymphocytosis,CNKL）是一组罕见的异质性疾病,该病病因不明,大部分呈良性、惰性过程,可自行缓解,少数向恶性转化[1]。展开更多
Introduction. Pseudomigraine with temporary neurological symptoms and lymphocytic pleocytosis is a rare syndrome resolving within less than 3 months. Case report. A young 17- year-old woman without previous medical hi...Introduction. Pseudomigraine with temporary neurological symptoms and lymphocytic pleocytosis is a rare syndrome resolving within less than 3 months. Case report. A young 17- year-old woman without previous medical history was admitted to the hospital because of right motor weakness and language disturbances. The symptoms resolved in a few hours and were followed by severe left headaches with important vegetative signs. Several similar episodes were noted in the previous 10 days. Cranial MRI was normal. EEGshowed important slowing of the cerebral electrogenesis. More than 250 lymphocytic cells were found at CSF analysis. Outcome was spontaneously favorable, without similar symptoms after 6- month follow-up. Conclusion. Pseudomigraine with lymphocytic pleocytosis seems to be a particular syndrome of unknown origin. This is an elimination diagnosis, generally with a benign course.展开更多
文摘短暂性头痛和神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache and neu-rological deficits with cerebrospinal fluid lymphocyto-sis,HaNDL)以短暂的神经功能缺损和偏头痛样头痛发作为主要临床表现,伴脑脊液淋巴细胞增多,一般3个月内自发缓解,是一种自限性疾病[1]。
文摘短暂头痛、神经功能缺损伴脑脊液淋巴细胞增多综合征(syndrome of transient headache andneurolo-gical deficits with cerebrospinal fluid lymphocytosis,HaNDL)主要表现为发作性头痛伴有短暂性神经功能缺损,实验室检查可发现脑脊液淋巴细胞增多,可呈反复发作病程。国内鲜有报道,可能是因为HaNDL综合征易与病毒性脑炎、短暂性脑缺血发作等疾病混淆,其次考虑与认知不足有关。为提高对此综合征的认识,本文就其病因、临床特征、诊断标准、鉴别诊断及治疗方面的进展进行了综述。
文摘慢性自然杀伤（naturekiller,NK）细胞起源于骨髓造血干细胞,呈大颗粒细胞形态,约占外周血淋巴细胞的5%,主要参与机体的非特异免疫。慢性NK细胞淋巴细胞增多症（chronic NK cell lymphocytosis,CNKL）是一组罕见的异质性疾病,该病病因不明,大部分呈良性、惰性过程,可自行缓解,少数向恶性转化[1]。
文摘Introduction. Pseudomigraine with temporary neurological symptoms and lymphocytic pleocytosis is a rare syndrome resolving within less than 3 months. Case report. A young 17- year-old woman without previous medical history was admitted to the hospital because of right motor weakness and language disturbances. The symptoms resolved in a few hours and were followed by severe left headaches with important vegetative signs. Several similar episodes were noted in the previous 10 days. Cranial MRI was normal. EEGshowed important slowing of the cerebral electrogenesis. More than 250 lymphocytic cells were found at CSF analysis. Outcome was spontaneously favorable, without similar symptoms after 6- month follow-up. Conclusion. Pseudomigraine with lymphocytic pleocytosis seems to be a particular syndrome of unknown origin. This is an elimination diagnosis, generally with a benign course.
