Based on the knowledge representation and knowledge reasoning, this paper addresses the creation of the multi-attribute knowledge base on the basis of hybrid knowledge representation, with the help of object-oriented ...Based on the knowledge representation and knowledge reasoning, this paper addresses the creation of the multi-attribute knowledge base on the basis of hybrid knowledge representation, with the help of object-oriented programming language and relational database. Compared with general knowledge base, multi-attribute knowledge base can enhance the ability of knowledge processing and application; integrate the heterogeneous knowledge, such as model, symbol, case-based sample knowledge; and support the whole decision process by integrated reasoning.展开更多
Cerium （III） tetraphenylporphyrin nitrate Ce（TPP）NO3 was synthesized by using meso- tetraphenylporphyrin （TPP） and Ce（NO3）.6H20 in mixture solution of CHC13 and C2HsOH （V：V=1：1）. The complex was characteri...Cerium （III） tetraphenylporphyrin nitrate Ce（TPP）NO3 was synthesized by using meso- tetraphenylporphyrin （TPP） and Ce（NO3）.6H20 in mixture solution of CHC13 and C2HsOH （V：V=1：1）. The complex was characterized by UV-Vis, FT-IR, conventional fluorescence, MALDI-TOF-MS, and ^1H NMR spectral techniques. The structure of complex was proposed viaSpectral analyses, in which tetraphenylporphyrin was coordinated to a cerium ion in a tetradentate fashion, while one nitrate was coordinated to the same cerium ion. After bubbling NO to the solution of Ce（TPP）NO3 in CH2Cl2, spectral analyses suggested that Ce（TPP）NO3 could interact with NO to form a novel complex of Ce（TPP）（NO）NO3, and NO was coordinated to the center cerium ion. When nitrogen was poured into the Ce（TPP）（NO）（NO3） solution, the complex could be reduced to Ce（TPP）NO3.展开更多
This paper presents a new method to study the interaction between tangerine peel and beer by absorption spectrum.The author explores the change laws and the differences of the absorbance on some wave band from the abs...This paper presents a new method to study the interaction between tangerine peel and beer by absorption spectrum.The author explores the change laws and the differences of the absorbance on some wave band from the absorption spectrums of tangerine peel and the mixture of tangerine peel and beer. The results show that there is an obvious difference around 323 nm though the absorbance values of the two samples are almost similar in the most bands. The absorbance value of the mixture is obviously greater than that of tangerine peel at 276 nm in the spectrums, and there is a shift of the peak position in the absorption spectrum of the mixture, which shows the differences of the absorbance values and the peak positions of the two samples. Through comparing the characteristics of the two samples' absorption spectrums, a new method for researching new pharmacological action of tangerine peel is presented in this paper. The result indicates that the technology of spectrum analysis will play an important role in the research and development of Chinese herbal pharmacology and new pharmacology.展开更多
Objectives:This study is aimed to explore the blending process of Dahuang soda tablets.These are composed of two active pharmaceutical ingredients(APIs,emodin and emodin methyl ether)and four kinds of excipients(sodiu...Objectives:This study is aimed to explore the blending process of Dahuang soda tablets.These are composed of two active pharmaceutical ingredients(APIs,emodin and emodin methyl ether)and four kinds of excipients(sodium bicarbonate,starch,sucrose,and magnesium stearate).Also,the objective is to develop a more robust model to determine the blending end-point.Methods:Qualitative and quantitative methods based on near-infrared(NIR)spectroscopy were established to monitor the homogeneity of the powder during the blending process.A calibration set consisting of samples from 15 batches was used to develop two types of calibration models with the partial least squares regression(PLSR)method to explore the influence of density on the model robustness.The principal component analysis-moving block standard deviation(PCA-MBSD)method was used for the end-point determination of the blending with the process spectra.Results:The model with different densities showed better prediction performance and robustness than the model with fixed powder density.In addition,the blending end-points of APIs and excipients were inconsistent because of the differences in the physical properties and chemical contents among the materials of the design batches.For the complex systems of multi-components,using the PCA-MBSD method to determine the blending end-point of each component is difficult.In these conditions,a quantitative method is a more suitable alternative.Conclusions:Our results demonstrated that the effect of density plays an important role in improving the performance of the model,and a robust modeling method has been developed.展开更多
Based on the data obtained from a survey recently made in Shanghai, this paper presents the hybrid technique for risk analysis and evaluation of some diseases. After determination of main risk factors of these disease...Based on the data obtained from a survey recently made in Shanghai, this paper presents the hybrid technique for risk analysis and evaluation of some diseases. After determination of main risk factors of these diseases by analysis of variance, the authors introduce a new concept ’Illness Fuzzy Set’ and use fuzzy comprehensive evaluation to evaluate the risk of suffering from a disease for residents. Optimal technique is used to determine the weights wi in fuzzy comprehensive evaluation, and a new method ’Improved Information Distribution’ is also introduced for the treatment of small sample problem. It is shown that the results obtained by using the hybrid technique are better than by using single fuzzy technique or single statistical method.展开更多
基金Supported by National Natural Science Foundation of China(No.70271002)
文摘Based on the knowledge representation and knowledge reasoning, this paper addresses the creation of the multi-attribute knowledge base on the basis of hybrid knowledge representation, with the help of object-oriented programming language and relational database. Compared with general knowledge base, multi-attribute knowledge base can enhance the ability of knowledge processing and application; integrate the heterogeneous knowledge, such as model, symbol, case-based sample knowledge; and support the whole decision process by integrated reasoning.
基金ACKNOWLEDGMENTS This work was supported by the ＂Western Light＂ Visiting Scholar Plan, the Program for New Century Excellent Talents in University （No.NCET-12-1017）, the Program for Grassland Excellent Talents of Inner Mongolia Autonomous Region, the Inner Mengolia Science Technology Plan, the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region （No.NJYT-12-B13）, the Natural Science Foundation of Inner Mongolia Autonomous Region （No.2011BS0601, China）, the Inner Mongolia Talented People Development Fund, and Yongfeng Boyuan Industry Co., Ltd. Jiangxi Province, China.
文摘Cerium （III） tetraphenylporphyrin nitrate Ce（TPP）NO3 was synthesized by using meso- tetraphenylporphyrin （TPP） and Ce（NO3）.6H20 in mixture solution of CHC13 and C2HsOH （V：V=1：1）. The complex was characterized by UV-Vis, FT-IR, conventional fluorescence, MALDI-TOF-MS, and ^1H NMR spectral techniques. The structure of complex was proposed viaSpectral analyses, in which tetraphenylporphyrin was coordinated to a cerium ion in a tetradentate fashion, while one nitrate was coordinated to the same cerium ion. After bubbling NO to the solution of Ce（TPP）NO3 in CH2Cl2, spectral analyses suggested that Ce（TPP）NO3 could interact with NO to form a novel complex of Ce（TPP）（NO）NO3, and NO was coordinated to the center cerium ion. When nitrogen was poured into the Ce（TPP）（NO）（NO3） solution, the complex could be reduced to Ce（TPP）NO3.
基金National Natural Science Foundation of Chinagrant number:10172043+1 种基金International Science and Technology Cooperation Programgrant number:BZ2008060
文摘This paper presents a new method to study the interaction between tangerine peel and beer by absorption spectrum.The author explores the change laws and the differences of the absorbance on some wave band from the absorption spectrums of tangerine peel and the mixture of tangerine peel and beer. The results show that there is an obvious difference around 323 nm though the absorbance values of the two samples are almost similar in the most bands. The absorbance value of the mixture is obviously greater than that of tangerine peel at 276 nm in the spectrums, and there is a shift of the peak position in the absorption spectrum of the mixture, which shows the differences of the absorbance values and the peak positions of the two samples. Through comparing the characteristics of the two samples' absorption spectrums, a new method for researching new pharmacological action of tangerine peel is presented in this paper. The result indicates that the technology of spectrum analysis will play an important role in the research and development of Chinese herbal pharmacology and new pharmacology.
基金the National S&T Major Project of China(No.2018ZX09201011)。
文摘Objectives:This study is aimed to explore the blending process of Dahuang soda tablets.These are composed of two active pharmaceutical ingredients(APIs,emodin and emodin methyl ether)and four kinds of excipients(sodium bicarbonate,starch,sucrose,and magnesium stearate).Also,the objective is to develop a more robust model to determine the blending end-point.Methods:Qualitative and quantitative methods based on near-infrared(NIR)spectroscopy were established to monitor the homogeneity of the powder during the blending process.A calibration set consisting of samples from 15 batches was used to develop two types of calibration models with the partial least squares regression(PLSR)method to explore the influence of density on the model robustness.The principal component analysis-moving block standard deviation(PCA-MBSD)method was used for the end-point determination of the blending with the process spectra.Results:The model with different densities showed better prediction performance and robustness than the model with fixed powder density.In addition,the blending end-points of APIs and excipients were inconsistent because of the differences in the physical properties and chemical contents among the materials of the design batches.For the complex systems of multi-components,using the PCA-MBSD method to determine the blending end-point of each component is difficult.In these conditions,a quantitative method is a more suitable alternative.Conclusions:Our results demonstrated that the effect of density plays an important role in improving the performance of the model,and a robust modeling method has been developed.
基金the National Natural Science Foundation of China (No. 19831020).
文摘Based on the data obtained from a survey recently made in Shanghai, this paper presents the hybrid technique for risk analysis and evaluation of some diseases. After determination of main risk factors of these diseases by analysis of variance, the authors introduce a new concept ’Illness Fuzzy Set’ and use fuzzy comprehensive evaluation to evaluate the risk of suffering from a disease for residents. Optimal technique is used to determine the weights wi in fuzzy comprehensive evaluation, and a new method ’Improved Information Distribution’ is also introduced for the treatment of small sample problem. It is shown that the results obtained by using the hybrid technique are better than by using single fuzzy technique or single statistical method.
