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混合实验法优化含胆固醇微乳处方 被引量:4
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作者 王丹薇 杜红 +6 位作者 朱庆文 李海燕 杨学智 王玺玺 韩天 王超臣 牛欣 《北京中医药》 2013年第4期304-307,共4页
目的考察卵磷脂与胆盐作为混合表面活性剂制备含胆固醇微乳液的可行性,并对微乳处方进行优化。方法采用混合实验法筛选微乳处方,以表面活性剂、助表面活性剂和油作为自变量,粒径作为因变量,用数学方程和效应曲线表示自变量与因变量的关... 目的考察卵磷脂与胆盐作为混合表面活性剂制备含胆固醇微乳液的可行性,并对微乳处方进行优化。方法采用混合实验法筛选微乳处方,以表面活性剂、助表面活性剂和油作为自变量,粒径作为因变量,用数学方程和效应曲线表示自变量与因变量的关系,据此优化微乳处方,并对微乳液的物理稳定性初步进行判定。结果优化的微乳平均粒径为19.12 nm,多分散指数(PDI)平均值为0.153,物理稳定性良好。结论卵磷脂与胆盐可作为表面活性剂制备含胆固醇微乳,混合实验法能够客观地优化微乳处方,优化的微乳粒径分布均匀,性质稳定。 展开更多
关键词 卵磷脂 胆盐 胆固醇 微乳 混合实验法
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A Practical Hull Form Design of Ferry Using Hybrid Scheme Method and Performing Experiment
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作者 Suandar Baso Wardina Suwedy Rosmani Lukman Bochary Andi Ardianti 《Journal of Shipping and Ocean Engineering》 2015年第1期1-8,共8页
Prediction of ship performance in preliminary ship design is an important consideration. It could guarantee ship in safe and comfort. However, many design works did not involve simultaneously ship performances predict... Prediction of ship performance in preliminary ship design is an important consideration. It could guarantee ship in safe and comfort. However, many design works did not involve simultaneously ship performances predictions in preliminary design. Moreover, ship designers sometimes modified a ship form to obtain proper design without ship performance consideration. Therefore, this study concerns on predictions of total resistance and added wave resistance of a ferry using a hybrid particle-grid method and then its motions response after modifying bow and stern parts by conducting experiment. Research results show total resistance and added wave resistance have a significant different, therefore, it would be an important consideration in determining ship powering in preliminary ship design. The non-dimensional added wave resistance increases in increasing wave length from λ/Lpp = 0.5 to 1.0 and it decreases after L/λ = 1.0. In addition, it tends to decrease caused by increasing ship speed. The comparison of averaged heave and pitch amplitudes between basic forms after modifying bow and stem parts is quiet similar. However, the rolling amplitude of the modified form is significantly higher comparing with the basic form. We conclude that a ship could be design in preliminary design take into account performances predictions by using numerical method and experimental work. 展开更多
关键词 Resistance added wave resistance heave motion pitch motion rolling motion.
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Calorimetry is not color-blind. Molecular insights on association processes in surfactant-polymer mixtures derived from calorimetric experiments
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作者 LOH Watson BRINATTI Cesar 《Science China Chemistry》 SCIE EI CAS 2011年第12期2024-2027,共4页
This comment will review and discuss recent results obtained with the use of calorimetry in assessing molecular information from complex phenomena such as association in surfactant/polymer mixtures. These examples wer... This comment will review and discuss recent results obtained with the use of calorimetry in assessing molecular information from complex phenomena such as association in surfactant/polymer mixtures. These examples were selected to support the view that it is possible to ally the great sensitivity of modem calorimeters with carefully planned experiments and, sometimes, ancillary techniques in order to derive detailed information on molecular interactions. 展开更多
关键词 CALORIMETRY polymer-surfatant interaction SELF-ASSEMBLY
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