Warming yang is one of the most important therapeutic methods for treating diseases. In Peaceful Holy Benevolent Prescriptions (太平圣惠方 a collection of more than ten thousand formulas) written by Dr. Wang Huaiyin ...Warming yang is one of the most important therapeutic methods for treating diseases. In Peaceful Holy Benevolent Prescriptions (太平圣惠方 a collection of more than ten thousand formulas) written by Dr. Wang Huaiyin (王怀隐) et al in the Song Dynasty in 992 AD, more than one hundred formulas for treating diabetes are all complied with the principles of supplementing qi and nourishing yin. Dr. Liu Hejian (刘河间) in the period of Jin and Yuan Dynasty advocated that it should be treated with the principles of clearing away pathogenic heat and fire, and supplementing qi and nourishing yin. Dr. Huang Kunzai (黄坤载) in the Qing Dynasty held that diabetes should be treated by supplementing qi and nourishing yin.展开更多
Objective:To investigate the serotypes and auxotypes distribution of Neisseria gonorrhoeae in Guangzhou. Method: 131 strains of Neisseria gonorrhoeae wereserotyped by co-agglutination test and 108 strains wereauxotype...Objective:To investigate the serotypes and auxotypes distribution of Neisseria gonorrhoeae in Guangzhou. Method: 131 strains of Neisseria gonorrhoeae wereserotyped by co-agglutination test and 108 strains wereauxotyped by La Scolea's method. Results: Out of 131 strains of Neisseria gonorrhoeae,87.8% (115/131) were WⅡ/WⅢ, while 9.9% (13/131) wereWⅠ. The most important auxotypes were Proto, Pro and ILe,42.6% (46/108), 21.3% (23/108) and 12.0%, respectively. WⅡ/WⅢ was distributed among the all auxotypes aboveand WI found only in both Proto and Pro. Conclusion: The study illustrated the prevailing serotype,WⅡ/WⅢ, and higher prevalence of Ile- in Guangzhou.展开更多
AIM:Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC),relatively few reports are available on HCC in primary biliary cirrhosis.High plasma nociceptin (N/OFQ) level has been shown in ...AIM:Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC),relatively few reports are available on HCC in primary biliary cirrhosis.High plasma nociceptin (N/OFQ) level has been shown in Wilson disease and in patients with acute and chronic pain. METHODS:We report a follow-up case of HCC,which developed in a patient with primary biliary cirrhosis.The tumor appeared 18 years after the diagnosis of PBC and led to death within two years.Alfa fetoprotein and serum nociceptin levels were monitored before and during the development of HCC. Nociceptin content was also measured in the tumor tissue. RESULTS:The importance and the curiosity of the presented case was the novel finding of the progressive elevation of plasma nociceptin level up to 17-fold (172 pg/mL) above the baseline (9.2±1.8 pg/mL),parallel with the elevation of alpha fetoprotein (from 13 ng/mL up to 3 480 ng/mL) during tumor development.Nociceptin content was more than 15-fold higher in the neoplastic tissue (0.16 pg/mg) than that in the tumor- free liver tissue samples (0.01 pg/mg) taken during the autopsy. CONCLUSION:Results are in concordance with our previous observation that a very high plasma nociceptin level may be considered as an indicator for hepatocellular carcinoma.展开更多
Objectives: To explore the relationship betweenquantitative Treponema pallidum DNA (TP-DNA) PCR testingand the Toludine Red Unheated Serum Test (TRUST) inpatients with syphilis before and after treatment, and evaluate...Objectives: To explore the relationship betweenquantitative Treponema pallidum DNA (TP-DNA) PCR testingand the Toludine Red Unheated Serum Test (TRUST) inpatients with syphilis before and after treatment, and evaluatethe clinical value of quantitative TP-DNA testing in thediagnosis and treatment evaluation of syphilis. Methods: 29 patients with primary (12 cases) or secondary(17 cases) syphilis, who met the criteria set for this study wererecruited as subjects. All patients were treated with 2.4 millionunits benzathine penicillin IM weekly for 3 weeks.Quantitative tests of TP-DNA in the patients' plasma wereperformed using FQ-PCR before and after the treatment.Serologic tests including TRUST and TPPA were alsoperformed. Results: Before the treatment, 9 out of 12 primary syphilispatients (75%) and all secondary syphilis patients (17/17)tested positive for Treponema pallidum (TP) by TP-DNAtesting. The average quantitative test values of TP-DNA inprimary and secondary syphilis patients were (3.38±2.34)×10~4and (5.73±1.33)×10~6 copies/ml, respectively. After threemonths of treatment, 1 of the 9 primary and 5 out of 17secondary syphilis patients were positive upon TP-DNAtesting, respectively. The average quantities of TP-DNA were2.01×10~2 copies/ml in primary and 5.87×10~2 copies/ml insecondary syphilis patients with positive TRUST and TP-DNAtests, and 3.09×10~2 copies/ml for those with negative TRUSTrespectively. After nine months of treatment, all the primaryand secondary syphilis patients were negative upon TP-DNAtesting, while all primary and 14 of 17 (82.35%) secondarysyphilis patients showed negative TRUST results. Conclusion: That the results of TP-DNA tests are notconsistent with those or TRUST before and after treatmentindicates that quantitative TP-DNA testing may have valuableclinical significance in the early diagnosis and evaluation oftreatment regimens for syphilis.展开更多
Underground coal gasification is one of the clean technologies of in-situ coal utilization.Hydrogen production from underground gasification of lignite was investigated in this study based on simulation experiments.Py...Underground coal gasification is one of the clean technologies of in-situ coal utilization.Hydrogen production from underground gasification of lignite was investigated in this study based on simulation experiments.Pyrolysis of lignite, gasification activity, oxygen-steam gasification and the effect of groundwater influx were studied.As well, the advantages of lignite for stable underground gasification were analyzed.The results indicate that lignite has a high activity for gasification.Coal pyrolysis is an important source of hydrogen emission.Under special heating conditions, hydrogen is released from coal seams at temperatures above 350 °C and reaches its maximum value between 725 and 825 °C.Gas with a hydrogen concentration of 40% to 50% can be continuously obtained by oxygen-steam injection at an optimum ratio of steam to oxygen, while lignite properties will ensure stable gasification.Groundwater influx can be utilized for hydrogen preparation under certain geological conditions through pressure control.Therefore, enhanced-hydrogen gas production through underground gasification of lignite has experimentally been proved.展开更多
Objective:To study the cellular immunity status of patientswith recurrent genital herpes. Methods: Serum levels of interlukin-2 and its solublereceptor and interlukin-6 were measured by ELISA in 34patients with recurr...Objective:To study the cellular immunity status of patientswith recurrent genital herpes. Methods: Serum levels of interlukin-2 and its solublereceptor and interlukin-6 were measured by ELISA in 34patients with recurrent genital herpes. Results: Serum levels of IL-2 and IL-6 were significantlydecreased in patients compared to healthy controls (P<0.01),and the level of sIL-2R was significantly increased in patientswith recurrent genital herpes (P<0.01). There were nosignificant differences in all variables amongst patientsregarding relapse stage and remission stage (P>0.05). Conclusion: There was a cellular immune deficiency inpatients with recurrent genital herpes.展开更多
The treatment of gastric carcinoma consists of neoadjuvant chemoradiation,partial gastrectomy,subtotal gastrectomy,total gastrectomy,extended resection,and postoperative chemotherapy.Currently,gastrectomy and extended...The treatment of gastric carcinoma consists of neoadjuvant chemoradiation,partial gastrectomy,subtotal gastrectomy,total gastrectomy,extended resection,and postoperative chemotherapy.Currently,gastrectomy and extended lymphadenectomy is the optimal choice for late gastric carcinoma.Postoperative complications are common after total gastrectomy including hemorrhage,anastomotic leakage,f istula,and obstruction.However,deep venous thrombosis(DVT) is an uncommon complication after gastrectomy for gastric carcinoma.We describe a case of a 68-year-old female patient with DVT after gastrectomy for gastric carcinoma.The patient was treated with anticoagulants and thrombolytics and subjected to necessary laboratory monitoring.The patient recovered well after treatment and was symptom-free during a 3-mo follow-up.We conclude that correct diagnosis and treatment of DVT are crucial.展开更多
Objective： To explore clinical and laboratory features and significance of detecting serum carbohydrate antigen 125 （CA125） in immunoglobulin E （IgE） multiple myeloma. Methods： We reported the clinical findings ...Objective： To explore clinical and laboratory features and significance of detecting serum carbohydrate antigen 125 （CA125） in immunoglobulin E （IgE） multiple myeloma. Methods： We reported the clinical findings of a male patient with IgE myeloma and elevated level of serum CA 125 and reviewed the literature. Results： Laboratory tests of this patient on admission showed extremely high serum IgE and CA125, a bone marrow aspirate revealed abnormal plasma cells （38.4% of nucleated cells： 16.4% mature and 22% atypical）, and in bone marrow biopsy, immunoperoxidase staining showed positive cytoplasmic staining for IgE and n light chain within the vast majority of plasma cells. Computed tomography （CT） bone scans indicated wedge shape change and compressive fracture of thoracic vertebrae, and emission computed tomography （ECT） discovered multiple punctiform aggregation of radiation in both cervical ribs and spine. The serum IgE and CA 125 gradually decreased to normal limits after eight cycles of chemotherapy. This patient is alive well with an 18-month complete remission. Conclusion： We reported the first case of IgE myeloma with elevated level of serum CA 125. To further evaluate clinical characteristics and significance of CA 125 in IgE myeloma, more cases are needed.展开更多
Antivenom is the most effective method currently available for the treatment of poisonous snake bite. Allergic reactions to antivenom have been reported in the past. Here we shared a case of allergic re- actions to an...Antivenom is the most effective method currently available for the treatment of poisonous snake bite. Allergic reactions to antivenom have been reported in the past. Here we shared a case of allergic re- actions to antivenom in an old male patient who was bitten twice by the same snake （probably same one） at the same biting site within a month whereas the patient did not show any allergic disorder in the first bitten. Envenomations twice in a short period time by the same kind of snake are very rare. Physician should be alert to the occurrence of allergic reactions in treating this type of patients with antivenom. The skin allergy test has a certain value in predicting the allergic response before the second use of antivenom. Desensitization may reduce the incidence of allergic reactions, but this is insufficient. Rather than non-lgE-mediated immediate hypersensitivity, patients receiving the second treatment of antivenom may develop IgE-mediated immediate hypersensitivity. Once happened, the antivenom treatment should be stopped promptly and anti-allergy treatment should be given immediately.展开更多
文摘Warming yang is one of the most important therapeutic methods for treating diseases. In Peaceful Holy Benevolent Prescriptions (太平圣惠方 a collection of more than ten thousand formulas) written by Dr. Wang Huaiyin (王怀隐) et al in the Song Dynasty in 992 AD, more than one hundred formulas for treating diabetes are all complied with the principles of supplementing qi and nourishing yin. Dr. Liu Hejian (刘河间) in the period of Jin and Yuan Dynasty advocated that it should be treated with the principles of clearing away pathogenic heat and fire, and supplementing qi and nourishing yin. Dr. Huang Kunzai (黄坤载) in the Qing Dynasty held that diabetes should be treated by supplementing qi and nourishing yin.
文摘Objective:To investigate the serotypes and auxotypes distribution of Neisseria gonorrhoeae in Guangzhou. Method: 131 strains of Neisseria gonorrhoeae wereserotyped by co-agglutination test and 108 strains wereauxotyped by La Scolea's method. Results: Out of 131 strains of Neisseria gonorrhoeae,87.8% (115/131) were WⅡ/WⅢ, while 9.9% (13/131) wereWⅠ. The most important auxotypes were Proto, Pro and ILe,42.6% (46/108), 21.3% (23/108) and 12.0%, respectively. WⅡ/WⅢ was distributed among the all auxotypes aboveand WI found only in both Proto and Pro. Conclusion: The study illustrated the prevailing serotype,WⅡ/WⅢ, and higher prevalence of Ile- in Guangzhou.
文摘AIM:Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC),relatively few reports are available on HCC in primary biliary cirrhosis.High plasma nociceptin (N/OFQ) level has been shown in Wilson disease and in patients with acute and chronic pain. METHODS:We report a follow-up case of HCC,which developed in a patient with primary biliary cirrhosis.The tumor appeared 18 years after the diagnosis of PBC and led to death within two years.Alfa fetoprotein and serum nociceptin levels were monitored before and during the development of HCC. Nociceptin content was also measured in the tumor tissue. RESULTS:The importance and the curiosity of the presented case was the novel finding of the progressive elevation of plasma nociceptin level up to 17-fold (172 pg/mL) above the baseline (9.2±1.8 pg/mL),parallel with the elevation of alpha fetoprotein (from 13 ng/mL up to 3 480 ng/mL) during tumor development.Nociceptin content was more than 15-fold higher in the neoplastic tissue (0.16 pg/mg) than that in the tumor- free liver tissue samples (0.01 pg/mg) taken during the autopsy. CONCLUSION:Results are in concordance with our previous observation that a very high plasma nociceptin level may be considered as an indicator for hepatocellular carcinoma.
文摘Objectives: To explore the relationship betweenquantitative Treponema pallidum DNA (TP-DNA) PCR testingand the Toludine Red Unheated Serum Test (TRUST) inpatients with syphilis before and after treatment, and evaluatethe clinical value of quantitative TP-DNA testing in thediagnosis and treatment evaluation of syphilis. Methods: 29 patients with primary (12 cases) or secondary(17 cases) syphilis, who met the criteria set for this study wererecruited as subjects. All patients were treated with 2.4 millionunits benzathine penicillin IM weekly for 3 weeks.Quantitative tests of TP-DNA in the patients' plasma wereperformed using FQ-PCR before and after the treatment.Serologic tests including TRUST and TPPA were alsoperformed. Results: Before the treatment, 9 out of 12 primary syphilispatients (75%) and all secondary syphilis patients (17/17)tested positive for Treponema pallidum (TP) by TP-DNAtesting. The average quantitative test values of TP-DNA inprimary and secondary syphilis patients were (3.38±2.34)×10~4and (5.73±1.33)×10~6 copies/ml, respectively. After threemonths of treatment, 1 of the 9 primary and 5 out of 17secondary syphilis patients were positive upon TP-DNAtesting, respectively. The average quantities of TP-DNA were2.01×10~2 copies/ml in primary and 5.87×10~2 copies/ml insecondary syphilis patients with positive TRUST and TP-DNAtests, and 3.09×10~2 copies/ml for those with negative TRUSTrespectively. After nine months of treatment, all the primaryand secondary syphilis patients were negative upon TP-DNAtesting, while all primary and 14 of 17 (82.35%) secondarysyphilis patients showed negative TRUST results. Conclusion: That the results of TP-DNA tests are notconsistent with those or TRUST before and after treatmentindicates that quantitative TP-DNA testing may have valuableclinical significance in the early diagnosis and evaluation oftreatment regimens for syphilis.
基金Projects 50876112 and 50674084 supported by the National Natural Science Foundation of China
文摘Underground coal gasification is one of the clean technologies of in-situ coal utilization.Hydrogen production from underground gasification of lignite was investigated in this study based on simulation experiments.Pyrolysis of lignite, gasification activity, oxygen-steam gasification and the effect of groundwater influx were studied.As well, the advantages of lignite for stable underground gasification were analyzed.The results indicate that lignite has a high activity for gasification.Coal pyrolysis is an important source of hydrogen emission.Under special heating conditions, hydrogen is released from coal seams at temperatures above 350 °C and reaches its maximum value between 725 and 825 °C.Gas with a hydrogen concentration of 40% to 50% can be continuously obtained by oxygen-steam injection at an optimum ratio of steam to oxygen, while lignite properties will ensure stable gasification.Groundwater influx can be utilized for hydrogen preparation under certain geological conditions through pressure control.Therefore, enhanced-hydrogen gas production through underground gasification of lignite has experimentally been proved.
文摘Objective:To study the cellular immunity status of patientswith recurrent genital herpes. Methods: Serum levels of interlukin-2 and its solublereceptor and interlukin-6 were measured by ELISA in 34patients with recurrent genital herpes. Results: Serum levels of IL-2 and IL-6 were significantlydecreased in patients compared to healthy controls (P<0.01),and the level of sIL-2R was significantly increased in patientswith recurrent genital herpes (P<0.01). There were nosignificant differences in all variables amongst patientsregarding relapse stage and remission stage (P>0.05). Conclusion: There was a cellular immune deficiency inpatients with recurrent genital herpes.
文摘The treatment of gastric carcinoma consists of neoadjuvant chemoradiation,partial gastrectomy,subtotal gastrectomy,total gastrectomy,extended resection,and postoperative chemotherapy.Currently,gastrectomy and extended lymphadenectomy is the optimal choice for late gastric carcinoma.Postoperative complications are common after total gastrectomy including hemorrhage,anastomotic leakage,f istula,and obstruction.However,deep venous thrombosis(DVT) is an uncommon complication after gastrectomy for gastric carcinoma.We describe a case of a 68-year-old female patient with DVT after gastrectomy for gastric carcinoma.The patient was treated with anticoagulants and thrombolytics and subjected to necessary laboratory monitoring.The patient recovered well after treatment and was symptom-free during a 3-mo follow-up.We conclude that correct diagnosis and treatment of DVT are crucial.
文摘Objective： To explore clinical and laboratory features and significance of detecting serum carbohydrate antigen 125 （CA125） in immunoglobulin E （IgE） multiple myeloma. Methods： We reported the clinical findings of a male patient with IgE myeloma and elevated level of serum CA 125 and reviewed the literature. Results： Laboratory tests of this patient on admission showed extremely high serum IgE and CA125, a bone marrow aspirate revealed abnormal plasma cells （38.4% of nucleated cells： 16.4% mature and 22% atypical）, and in bone marrow biopsy, immunoperoxidase staining showed positive cytoplasmic staining for IgE and n light chain within the vast majority of plasma cells. Computed tomography （CT） bone scans indicated wedge shape change and compressive fracture of thoracic vertebrae, and emission computed tomography （ECT） discovered multiple punctiform aggregation of radiation in both cervical ribs and spine. The serum IgE and CA 125 gradually decreased to normal limits after eight cycles of chemotherapy. This patient is alive well with an 18-month complete remission. Conclusion： We reported the first case of IgE myeloma with elevated level of serum CA 125. To further evaluate clinical characteristics and significance of CA 125 in IgE myeloma, more cases are needed.
文摘Antivenom is the most effective method currently available for the treatment of poisonous snake bite. Allergic reactions to antivenom have been reported in the past. Here we shared a case of allergic re- actions to antivenom in an old male patient who was bitten twice by the same snake （probably same one） at the same biting site within a month whereas the patient did not show any allergic disorder in the first bitten. Envenomations twice in a short period time by the same kind of snake are very rare. Physician should be alert to the occurrence of allergic reactions in treating this type of patients with antivenom. The skin allergy test has a certain value in predicting the allergic response before the second use of antivenom. Desensitization may reduce the incidence of allergic reactions, but this is insufficient. Rather than non-lgE-mediated immediate hypersensitivity, patients receiving the second treatment of antivenom may develop IgE-mediated immediate hypersensitivity. Once happened, the antivenom treatment should be stopped promptly and anti-allergy treatment should be given immediately.
