目的探讨门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入治疗小儿支原体肺炎的临床效果。方法将治疗对象150例,随机分为观察组与对照组各75例,两组均给予常规处理,观察组在常规处理的基础上,给予门冬氨酸阿奇霉素治疗,对照组则给予红霉素服用...目的探讨门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入治疗小儿支原体肺炎的临床效果。方法将治疗对象150例,随机分为观察组与对照组各75例,两组均给予常规处理,观察组在常规处理的基础上,给予门冬氨酸阿奇霉素治疗,对照组则给予红霉素服用,并将同等剂量红霉素加入5%葡萄糖200 m L内静脉点滴。两组均7 d为1疗程,连续治疗2个疗程后评定整体疗效,数据进行统计学处理(χ2检验)。结果两组患者痊愈、有效、无效、总有效率比较(χ2=9.101、7.245、10.010、8.979,均P<0.01),观察组整体疗效明显优于对照组,具有非常显著性差异;两组患者的纳差、腹部疼痛不适、皮疹、呕吐之不良反应发生情况比较(χ2=7.102、5.324、4.076、5.558,均P<0.05)观察组不良反应发生率显著低于对照组,差异有统计学意义。结论门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入对小儿支原体肺炎治疗效果尚佳,不良反应发生少。展开更多
Jerusalem artichoke is an economic crop widely planted in saline-alkaline soil. The use of Jerusalem artichoke is of great significance. In this study, the response surface method was employed to optimize the effects ...Jerusalem artichoke is an economic crop widely planted in saline-alkaline soil. The use of Jerusalem artichoke is of great significance. In this study, the response surface method was employed to optimize the effects of processing variables （extraction temperature, pH, extraction time, and liquid-to- solid ratio） on the yield of Jerusalem artichoke pectin. Under the optimal extraction conditions： pHl .52, 63.62 min, 100℃ and a liquid-to-solid ratio of 44.4 mL/g, the maximum pectin yield was predicted to be 18.76%. Experiments were conducted under these optimal conditions and a pectin yield of 18.52＋0.90% was obtained, which validated the model prediction. The effects of different drying methods （freeze drying, spray drying and vacuum drying） on the properties of Jerusalem artichoke pectin were evaluated and they were compared with apple pectin. FTIR spectral analysis showed no major structural differences in Jerusalem artichoke pectin samples produced by various drying treatments. The antioxidant activities of pectin dried by different methods were investigated using in vitro hydroxyl and DPPH radical scavenging systems. The results revealed that the activities of spray dried pectin （SDP） and apple pectin （AP） were stronger than those of vacuum oven dried pectin （ODP） and vacuum freeze dried pectin （FDP）. Therefore compared with the other two drying methods, the spray drying method was the best.展开更多
文摘目的探讨门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入治疗小儿支原体肺炎的临床效果。方法将治疗对象150例,随机分为观察组与对照组各75例,两组均给予常规处理,观察组在常规处理的基础上,给予门冬氨酸阿奇霉素治疗,对照组则给予红霉素服用,并将同等剂量红霉素加入5%葡萄糖200 m L内静脉点滴。两组均7 d为1疗程,连续治疗2个疗程后评定整体疗效,数据进行统计学处理(χ2检验)。结果两组患者痊愈、有效、无效、总有效率比较(χ2=9.101、7.245、10.010、8.979,均P<0.01),观察组整体疗效明显优于对照组,具有非常显著性差异;两组患者的纳差、腹部疼痛不适、皮疹、呕吐之不良反应发生情况比较(χ2=7.102、5.324、4.076、5.558,均P<0.05)观察组不良反应发生率显著低于对照组,差异有统计学意义。结论门冬氨酸阿奇霉素静滴辅助痰热清雾化吸入对小儿支原体肺炎治疗效果尚佳,不良反应发生少。
基金Supported by the National High Technology Research and Development Program of China(863 Program)(No.2012AA021205)the National Key Technology R&D Program of China(No.2011BAC02B04)
文摘Jerusalem artichoke is an economic crop widely planted in saline-alkaline soil. The use of Jerusalem artichoke is of great significance. In this study, the response surface method was employed to optimize the effects of processing variables （extraction temperature, pH, extraction time, and liquid-to- solid ratio） on the yield of Jerusalem artichoke pectin. Under the optimal extraction conditions： pHl .52, 63.62 min, 100℃ and a liquid-to-solid ratio of 44.4 mL/g, the maximum pectin yield was predicted to be 18.76%. Experiments were conducted under these optimal conditions and a pectin yield of 18.52＋0.90% was obtained, which validated the model prediction. The effects of different drying methods （freeze drying, spray drying and vacuum drying） on the properties of Jerusalem artichoke pectin were evaluated and they were compared with apple pectin. FTIR spectral analysis showed no major structural differences in Jerusalem artichoke pectin samples produced by various drying treatments. The antioxidant activities of pectin dried by different methods were investigated using in vitro hydroxyl and DPPH radical scavenging systems. The results revealed that the activities of spray dried pectin （SDP） and apple pectin （AP） were stronger than those of vacuum oven dried pectin （ODP） and vacuum freeze dried pectin （FDP）. Therefore compared with the other two drying methods, the spray drying method was the best.
