辽河坳陷西部凹陷潜山油气输导体系特征

针对辽河坳陷西部凹陷潜山油气输导体系特征、规模增储勘探方向不明确等问题,运用构造特征和演化史分析方法,结合典型潜山油气藏解剖,按潜山与成熟烃源岩接触关系,将西部凹陷潜山划分为源内、源边和源外3种类型,建立了不同类型潜山的油气输导模式。研究结果表明:西部凹陷源内型潜山具有裂缝型储层-断裂-不整合复式油气输导条件,输导体系最为有利,发育风化壳和内幕油气藏;源边型潜山单边以断面或不整合为主要输导通道,潜山含油气性及幅度受控于供油窗口的大小及潜山储层的发育程度;源外型潜山以通源断层为油气垂向运移通道,不整合为横向运移通道,主要发育风化壳型潜山油藏。研究成果对西部凹陷潜山下一步勘探方向和有利目标的优选具有重要的意义。

Changes in Levels of Endogenous Plant Hormones During Floret Development in Wheat Genotypes of Different Spike Sizes

The levels of endogenous plant hormones regulate floret development and degeneration, and thus grain set in flower crops. This study was undertaken to characterize the changes of endogenous hormone levels during floret development in three wheat ( Triticum aestivum L.) genotypes: “97J1' with the highest grain set and fertile florets per spike, “H8679' with the lowest grain set and fertile florets per spike, and a medium, “YM158'. The results showed that the peak level of ABA appeared between stamen and pistil differentiation and antherlobe formation of floret development, and the timing delayed with the size of spike (earliest in “H8679” and latest in “97J1”). From antherlobe formation to meiosis, the levels of ABA and GA 1+3 decreased sharply in the ears of “97J1”, while in the ears of “H8679” there was only a slight decrease in ABA, and even an increase in GA 1+3 . The ratio of isopentenyladenosine (iPA)/ABA and IAA/ABA in the ears of “97J1” increased sharply from antherlobe formation to meiosis, but changed only slightly in the ears of “H8679”. At antherlobe formation, IAA and GA 1+3 levels were higher in the ears of “97J1”, but lower in the ears of “H8679” than in the leaves. At meiosis, ABA, GA 1+3 and IAA levels in the “97J1” ears were much lower than in the leaves, but similar in “H8679”. These results indicated that the sharp decreases of ABA and GA 1+3 in ears from antherlobe formation to meiosis and the lowest maintenance at meiosis may be favorable for development of fertile florets and enhancement of grain set in wheat.

Relationship between Endogenous Hormones and Pod-length Development in Brassica napus L.

[Objective] The aim was to study the relationship between endogenous hormone levels and the pod lengths in Brassica napus L.[Method] Two specially-long pod lines H218 and H203,two normal pod length lines MSP334,Zhongyou 821 and two short pod lines ＂4101＂ and Zeng 11,were exploited as experimental materials,and the endogenous IAA,iPA,GA3 and ABA content in the pods of the materials were analyzed with the method of enzyme-linked immunosorbent assay（ELISA）.[Result] IAA contents in the specially-long pod lines were lower than those in the short pod lines on the 1st and 5th day after blossom.IAA contents on the 5th and 20th day were negatively correlated to the final pod length respectively.iPA contents in the specially-long pod lines were lower than those in the short pod lines on the 5th and 20th day.iPA content on the first day was positively correlated to the final pod length,but iPA content on the fifth day,the tenth day and the fifteenth day were negatively correlated to the final pod length.GA3 content on the 1st day was positively correlated to the final pod length.ABA content on the 1st day was negatively correlated to the final pod length.[Conclusion] It was shown that iPA and IAA played important roles in the development of pod length in the B.napus lines.

Changes of the Transcriptional Levels of Molecules Associated with Endogenous Antigen Processing and Presentation in Porcine Skin-derived Dendritic Cells Infected with PCV2 in vivo

[Objective] This study aimed to investigate the changes of the transcriptional levels of molecules associated with endogenous antigen processing and presenta- tion in porcine skin-derived dendritic cells infected with PCV2 in vivo. [Method] Healthy 40-day-old Landrace piglets were infected with porcine circovirus type 2 （PCV2） and euthanized on the 34, 7rd, 14th, 21st and 35th d post inoculation （DPI）. The porcine skin-derived dendritic cells （DCs） were collected to analyze the transcrip- tional levels of molecules （LMP7, UBP, MHC-I, calreticulin） associated with endogenous antigen processing and presentation by using real-time fluorescent quantitative PCR （real-time FQ-PCR）. [Result] The results showed that the level of LMP7 mR- NAs was reduced significantly on the 3DPI （P〈0.05）; the level of UBP mRNAs was consistently up-regulated, which increased significantly on the 21DPI and 35DPI （P〈 0.05）; the level of MHC-I mRNAs was significantly down-regulated on the 7DPI （P〈 0.05）; the level of calreticulin mRNAs was up-regulated slightly without significant dif- ference. [Conclusion] PCV2 can inhibit the endogenous antigen processing and presentation ability of porcine skin-derived DCs at early stages of infection.

China＇s Electricity Industry at the Crossroads： New Challenges for Developing the Right Model of Regulation

China is facing important challenges stemming from increasing rates of urbanization and aging population. To pursue its ＂harmonious society＂ objective without disrupting its path to development major overhauls are necessary in education, health, social security and above all in public services, particularly in electricity. China＇s electricity industry is at the crossroads. To meet the challenges, new models of regulation should be developed and applied. This paper examines the current state of the Chinese electricity industry and the burden it imposes on its public finances. It also reviews and critically examines the existing FIT （Europe） and RPS （USA） models of regulation and of promotion of renewable energies and advances on whether they are advantageous for China. It is argued that the electricity industry has already undergone important reforms but cross subsidies still exist, equivalent to 1.5% of China＇s GDP. Drastic rate rebalancing policies will create sustainability problems and a deterioration of China＇s public finances. To avoid such negative results, China has to further reform its electricity industry gradually and use wisely FIT-type programs to bring renewables into the grid and fulfill the Kyoto Protocol

Innovation in Chinese Agribusinesses： Internal Resources and External Networks

The existing literature on innovation concentrates mostly on large industrial firms and high-technology industries, whereas, little attention has been given to agribusiness. Empirical evidence regarding the driving forces behind innovation in agribusinesses in developing countries, China in particular is scarce. This paper helps fill that void. It develops a framework in which innovation results from synergies between internal resources and external networks. This paper applies and tests the framework using 2003-2005 data from a panel survey of 32 leading agribusiness firms in Shandong Province, China. The empirical results indicate the importance of internal resources, external networks and the synergies between them. We find that R＆D expenditures and the number of technical employees are internal resources that are both important to product innovation. Surprisingly, management quality is negatively related to the possession of a unique technology and new products as a proportion of all products. It is possible that management quality is associated with more formalization and rigidity in decision-making, hindering creativity and lengthening the new product development cycle. In order to develop innovative products, our results suggest that investing in R＆D and hiring more technical staff may be more effective approaches than spending on managerial talent.

Beyond Transformational Change： Incremental Transformational Change in Institutions

Much has been written and researched about transformational change and the exogenous events that result in radical institutional transformation （Di Maggio ＆ Powell, 1983; Hannan＆ Freeman, 1989; Fligstein, 1996; Zorn, Dobbin, ＆ Kwok, 2006）. Accounts are provided of external agents disturbing the existing stasis of the institution and transforming the institution into something else that reflect a new paradigm or set of interests. Often, what is neglected in these accounts is what fractures exist in the original institution that would make them vulnerable and allow penetration by exogenous influences. Mahoney and Thelen （20 l 0） went beyond a general model of change that described the collapse of one set of institutional norms to be replaced by another. The model of change they propose takes into account both exogenous as well as endogenous factors as being the source of institutional change. They went on to state a view that transformation change as being a result of abrupt, wholesale breakdown needs to be rethought to include incremental, endogenous shifts in thinking that can often result in fundamental transformations.

Strategic Focus and Business Model Organization： The Mean Field Analysis Approach

The objective of this research is to show a new methodology for modeling phenomena present in complex economic systems. The case study we analyzed is the adoption of open organization model among firms operating in a particular industry. A firm with an open system model creates and captures value taking advantage not only from the internal resource but also from external. The organization could approach to open model acquisition using different focus： external focus namely looking out of its boundary, acting and reacting to competitor innovation, costumers＇ changing, demand growth, or internal focus remaining inside its boundary improving its best capabilities ignoring what happened outside （Vagnani, Moran, ＆ Simoni, 2010）. The actors involved are firms, customers and suppliers linked together through a business to business model. The methodology is based on an Object-Oriented Analysis Field Model that allows to intuitively describe systems characterized by a large number of objects that interact, as in this case of a system composed by different organizational entities. The system simulation allows to analyze how the actors influence the acquisition and diffusion of the open organization model. This approach permits the generation of different classes of objects to represent all actors involved in the evolution of the system and to define the dynamics that determine their interaction. The solution of the model can be approximated using the Mean-Field analysis technique （Kurtz, 1978）, following the results proposed in Bobbio, Gribaudo, and Yelek （2008）. A qualitative result is illustrated in order to show the applicability of the proposed methodology and to emphasize its relevant features： flexible modeling approach, capacity of solving complex systems and output management facilities. The presented model is comprehensive and its scope is wide; it could be used to study the behavior of enterprises changing model in many different scenarios and situations. In future works quantitative results will be given, and different situations will be analyzed.

Effects of cannabinoid receptor type 2 on endogenous myocardial regeneration by activating cardiac progenitor cells in mouse infarcted heart

Cannabinoid receptor type 2(CB2)activation is recently reported to promote proliferation of some types of resident stem cells(e.g.,hematopoietic stem/progenitor cell or neural progenitor cell).Resident cardiac progenitor cell(CPC)activation and proliferation are crucial for endogenous cardiac regeneration and cardiac repair after myocardial infarction(MI).This study aims to explore the role and possible mechanisms of CB2receptor activation in enhancing myocardial repair.Our results revealed that CB2receptor agonist AM1241 can significantly increase CPCs by c-kit and Runx1 staining in ischemic myocardium as well as improve cardiomyocyte proliferation.AM1241 also decreased serum levels of MDA,TNF-αand IL-6 after MI.In addition,AM1241 can ameliorate left ventricular ejection fraction and fractional shortening,and reduce fibrosis.Moreover,AM1241 treatment markedly increased p-Akt and HO-1 expression,and promoted Nrf-2 nuclear translocation.However,PI3K inhibitor wortmannin eliminated these cardioprotective roles of AM1241.In conclusion,AM1241 could induce myocardial regeneration and improve cardiac function,which might be associated with PI3K/Akt/Nrf2 signaling pathway activation.Our findings may provide a promising strategy for cardiac endogenous regeneration after MI.

HETEROGENEITY, NONLINEARITY AND ENDOGENOUS MARKET VOLATILITY

This paper aims to contribute to the literature on the explanatory power of behavior models with heterogeneous agents. The authors present a new nonlinear structural stock market model which is a nonlinear deterministic process buffeted by dynamic noise. An exogenous noise is introduced to the model with the assumption of IID normal innovations of the fundamental value in order to investigate how noisy dynamics interacts with deterministic process. The market is composed of two typical trader types： the rational fundamentalists and the boundedly rational traders governed by greed and fear. The interaction between noise and deterministic element determines the evolution process of the system as key parameters are changed. The authors find the model is able to generate time series that exhibit dynamical and statistical properties closely resembling those of the S＆：P500 index, such as volatility clustering, fat tails （leptokurtosis）, autocorrelation in square and absolute return, larger amplitude, crashes and bubbles. The authors also investigate the nonlinear dependence structure in our data. The results indicate that the GARCH-type model cannot completely account for all nonlinearity in our simulated market, which is thus consistent with the results from real markets. It seems that the nonlinear structural model is more powerful to give a satisfied explanation to market behavior than the traditional stochastic approach.

Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase

Human endogenous retrovirus W env(HERV-W env) plays a critical role in many neuropsychological diseases such as schizophrenia and multiple sclerosis(MS). These diseases are accompanied by immunological reactions in the central nervous system(CNS). Microglia are important immunocytes in brain inflammation that can produce a gasotransmitter – nitric oxide(NO). NO not only plays a role in the function of neuronal cells but also participates in the pathogenesis of various neuropsychological diseases. In this study, we reported increased NO production in CHME-5 microglia cells after they were transfected with HERV-W env. Moreover, HERV-W env increased the expression and function of human inducible nitric oxide synthase(hi NOS) and enhanced the promoter activity of hi NOS. Microglial migration was also enhanced. These data revealed that HERV-W env might contribute to increase NO production and microglial migration ability in neuropsychological disorders by regulating the expression of inducible NOS. Results from this study might lead to the identification of novel targets for the treatment of neuropsychological diseases, including neuroinflammatory diseases, stroke, and neurodegenerative diseases.