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钻孔引流尿激酶溶凝治疗脑内血肿42例报告
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作者 邱振雄 《右江医学》 2002年第4期279-279,共1页
目的 :探讨颅骨钻孔置管引流尿激酶溶凝治疗脑内单发血肿的效果。方法 :对 42例脑内血肿进行回顾性分析。结果 :42例置管术后经 3~ 4次注入尿激酶后均顺利排空血肿 ,5天内顺利拔除引流管。结论 :血肿定位准确及术后尿激酶间隔
关键词 钻孔引流 尿激酶 溶凝治疗 脑内血肿 病例报告
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经额钻孔引流尿激酶溶凝治疗幕上高血压脑内血肿42例 被引量:3
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作者 张冠中 伦增军 李新钢 《中国医师进修杂志》 2010年第2期71-72,共2页
国内目前治疗高血压性脑出血有立体定向、沿长轴穿刺引流、骨窗开颅等方法。山东省枣庄市立医院神经外科2008年3月至2009年7月采用刘振川等经额钻孔引流尿激酶溶凝治疗幕上高血压脑内血肿42例,取得较好疗效,现报道如下。
关键词 高血压脑内血肿 溶凝治疗 钻孔引流 尿激酶 高血压性脑出血 立体定向 穿刺引流 骨窗开颅
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PROCOAGULANT EFFECTS OF THROMBOLYTICTHERAPY IN ACUTE MYOCARDIAL INFARCTION
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作者 Wang Y Liu Q +2 位作者 Zhu J Yuan Z Ma X 《Chinese Medical Sciences Journal》 CAS CSCD 2002年第1期36-39,共4页
To examine the procoagulant effects of thrombolytic agent on h emostasis and study the role of hemostatic markers as predictors of clinical outcomes. Methods. In the present study, eighteen patients with acute m... To examine the procoagulant effects of thrombolytic agent on h emostasis and study the role of hemostatic markers as predictors of clinical outcomes. Methods. In the present study, eighteen patients with acute myocardial in farction(AMI) received 1.5 or 2.0 million U nonspecific urokinase(UK), or 70~80 mg fibrin specific recombinant tissue plasminogen activator(rt PA)and did not use heparin until 8 hours after intravenous injection of the above agents. Eig ht patients with AMI and without thrombolytic therapy were enrolled as controls. Coagulant and thrombolytic activity markers included thrombin antithrombin Ⅲ complex (TAT), D dimer, fibrinogen (Fg), FMPV/Amax. All markers were determined before,immediately,1,2,4 and 8 hours after the administration of thrombolytic a gents respectively. Results. Molecular marker of thrombin generation——TAT showed an activated coa gulant state immediately after thrombolytic therapy. Level of TAT showed no sign ificant changes between every two observed phases in controls. However, level of TAT increased significantly from 4.95±1.75μg/L ( 4.63±1.37μg/L) to 14.71±3 .31μg/L ( 14.25±2.53μg/L) before and immediately after administration of thro mbolytic agents UK(or rt PA). There was significant difference between level of serum TAT of patients with and without thrombolytic therapy (P< 0.05). Patients achieving clinical reperfusion had lower TAT level than those failing in thromb olytic therapy, and higher FMPV/Amax level than controls. D dimer, a surrogate of thrombolytic activity increased markedly and Fg significantly declined afte r thrombolytic therapy(P< 0.05).Conclusions. Thrombin generation occurred in plasma in response to excess fibri nolysis induced by thrombolytic therapy. Both urokinase and rt PA had procoagul ant action. This transient activation of the coagulant system might contribute t o early reocclusion. These data provided the theoretical support for simultaneou s administration of anticoagulant therapy with thrombolytic agents. These result s also suggested that TAT might be useful in predicting clinical outcomes of p atients treated with thrombolytic therapy for AMI. 展开更多
关键词 acute myocardial infarction THROMBOLYSIS UROKINASE rt PA
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Analysis thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis in the lower extremities
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作者 刘心 张梅 +2 位作者 刘陕西 祈光裕 刘亚民 《Journal of Medical Colleges of PLA(China)》 CAS 2003年第2期99-101,共3页
Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein th... Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein thrombosis (DVT) in the lower extremities treated by thrombolysis with anticoagulation and dispersion drugs were analyzed retrospectively. Results: The thrombolytic effect was significant. After treatment, the deep veins were recanalized without regurgitation in 75.3% of the patients. The total effective rate was 100%. Only three patients had hemorrhagic complication, but none of the patients died. Conclusion: Thrombolysis with anticoagulation treatment is an effective and safe method for DVT at the early stage. 展开更多
关键词 deep venous thrombosis lower extremity vena anticoagulation treatment
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