脑机接口(brain-computer interface,BCI)的分类性能一定程度上取决于对脑电信号的预处理方法,这项研究提出了一种空域时域滤波的预处理方法,以解决人类视觉系统中的潜伏延迟对编码调制视觉诱发电位(c-VEP) BCI的目标识别性能的影响。...脑机接口(brain-computer interface,BCI)的分类性能一定程度上取决于对脑电信号的预处理方法,这项研究提出了一种空域时域滤波的预处理方法,以解决人类视觉系统中的潜伏延迟对编码调制视觉诱发电位(c-VEP) BCI的目标识别性能的影响。基于一个平均信号和单次试验信号之间的最小均方误差(the least mean square error,LMSE)创建时域空域滤波器,并且通过最小绝对收缩和选择算子(the least absolute shrinkage and selection operator,LASSO)将稀疏约束应用于滤波器的权重系数,并用模板匹配法来对目标进行识别。将算法应用于由63比特的M序列及其循环移位序列调制的16个目标的c-VEP BCI,并与通用的空域滤波算法典型相关分析(CCA)及空域时域逆滤波算法进行比较。结果表明本研究所提出的算法在分类准确率方面优于其他两种算法。展开更多
Herpes simplex virus (HSV) is a group of common human pathogens with two serotypes HSV-1 and HSV-2.The prevalence of HSV is worldwide.It primarily infects humans through epithelial cells,when it introduces a latent in...Herpes simplex virus (HSV) is a group of common human pathogens with two serotypes HSV-1 and HSV-2.The prevalence of HSV is worldwide.It primarily infects humans through epithelial cells,when it introduces a latent infection into the nervous system.During viral latency,only a region known as the latency-associated transcript (LAT) is expressed.The discovery of HSV miRNAs helps to draw a larger picture of the infection and pathogenesis of the virus.This review summarizes miRNAs found in HSV-1 and HSV-2 so far.The functional studies of miRNAs in HSV to date indicate that they play a stage-specific role coordinated with viral proteins to maintain the virus life cycle.展开更多
文摘脑机接口(brain-computer interface,BCI)的分类性能一定程度上取决于对脑电信号的预处理方法,这项研究提出了一种空域时域滤波的预处理方法,以解决人类视觉系统中的潜伏延迟对编码调制视觉诱发电位(c-VEP) BCI的目标识别性能的影响。基于一个平均信号和单次试验信号之间的最小均方误差(the least mean square error,LMSE)创建时域空域滤波器,并且通过最小绝对收缩和选择算子(the least absolute shrinkage and selection operator,LASSO)将稀疏约束应用于滤波器的权重系数,并用模板匹配法来对目标进行识别。将算法应用于由63比特的M序列及其循环移位序列调制的16个目标的c-VEP BCI,并与通用的空域滤波算法典型相关分析(CCA)及空域时域逆滤波算法进行比较。结果表明本研究所提出的算法在分类准确率方面优于其他两种算法。
基金supported by the National Natural Sciences Foundation of China(No.30670094 and 30700028)Youth Science Research Foundation of PUMC(No.2012X23)
文摘Herpes simplex virus (HSV) is a group of common human pathogens with two serotypes HSV-1 and HSV-2.The prevalence of HSV is worldwide.It primarily infects humans through epithelial cells,when it introduces a latent infection into the nervous system.During viral latency,only a region known as the latency-associated transcript (LAT) is expressed.The discovery of HSV miRNAs helps to draw a larger picture of the infection and pathogenesis of the virus.This review summarizes miRNAs found in HSV-1 and HSV-2 so far.The functional studies of miRNAs in HSV to date indicate that they play a stage-specific role coordinated with viral proteins to maintain the virus life cycle.
