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葡萄膜炎继发性青光眼与其他难治性青光眼Ahmed青光眼引流阀植入后前房反应的非随机对照研究 被引量:9
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作者 周民稳 王伟 +2 位作者 黄文彬 陈士达 张秀兰 《中华实验眼科杂志》 CAS CSCD 北大核心 2015年第3期241-245,共5页
背景 葡萄膜炎继发性青光眼患者由于葡萄膜的炎症而导致血-房水屏障的破坏,局部手术的创伤刺激可加重炎症反应,对术眼前房炎症反应进行定量检测可监测眼部反应程度. 目的 探讨葡萄膜炎继发性青光眼患者行Ahmed青光眼引流阀植入术后前房... 背景 葡萄膜炎继发性青光眼患者由于葡萄膜的炎症而导致血-房水屏障的破坏,局部手术的创伤刺激可加重炎症反应,对术眼前房炎症反应进行定量检测可监测眼部反应程度. 目的 探讨葡萄膜炎继发性青光眼患者行Ahmed青光眼引流阀植入术后前房内炎症反应是否重于其他类型的难治性青光眼.方法 采用前瞻性非随机对照的病例对照研究方法,于2011年10月至2012年7月纳入在中山大学中山眼科中心确诊的难治性青光眼29例29眼,分为葡萄膜炎继发性青光眼组(10眼)及其他类型的难治性青光眼组(19眼),2个组间术眼术前性别、年龄、眼压及房水闪辉值等基线特征匹配.所有患者均接受Ahmed房水引流阀植入术并随访3个月,记录术前、术后1d、3d、1周、2周、1个月和3个月术眼的眼压,同时采用FC-2000激光蛋白细胞检测仪定量测定术眼的房水闪辉值,以光粒子数/ms表示.比较2个组间房水引流阀植入术后房水闪辉值的不同,对术眼手术前后眼压值变化与房水闪辉值变化的关系进行分析. 结果 葡萄膜炎继发性青光眼组术后1d、3d和1周房水闪辉值分别为[21.10 (10.50,38.58)]、[88.00(23.55,168.63)]和[29.90(8.90,65.18)]光粒子数/ms,均明显高于术前的[13.53(7.60,24.00)]光粒子数/ms,差异均有统计学意义(均P<0.01),术后1个月和3个月房水闪辉值分别为[6.45 (4.70,13.50)]光粒子数/ms和[8.95 (6.23,18.20)]光粒子数/ms,均低于术前值,差异均有统计学意义(均P<0.01);其他类型青光眼组遵循同样的趋势.术后3个月葡萄膜炎继发性青光眼组术眼房水闪辉值明显高于其他类型青光眼组,差异有统计学意义(q=-3.445,P<0.01).术后2个组间眼压的比较差异无统计学意义(P>0.05).所有患者术眼术后眼压值均逐渐下降,术前及术后1d、3d、1周、2周、1个月和3个月术眼眼压与前房闪辉值间均无明显相关性(rs =0.136,P=0.481;rs=0.019,P=0.922;rs =-0.035,P=0.858;r,=0.317,P=0.094;rs=0.034,P=0.861;rs=-0.094,P=0.628;rs=0.065,P=0.738). 结论 FC-2000激光蛋白细胞检测仪检测证实Ahmed房水引流阀植入术可导致术眼术后早期的前房炎症反应,葡萄膜炎继发性青光眼患者术后炎症反应的恢复较缓慢,术后3个月时房水闪辉值仍高于其他类型的难治性青光眼. 展开更多
关键词 葡萄膜炎继发性青光眼/手术 青光眼引流植入物 房水/细胞学 激光/诊断应用 光度测定/方法 眼压 血-房水屏障 Ahmed房水引流阀植入术
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Application of Tunable Diode Laser Absorption Spectroscopy with Optical Hollow Fiber to Engine Exhaust Gas Measurement
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作者 Akira Adachi Yoshihiro Deguchi Shinichirou Konishi 《Journal of Mechanics Engineering and Automation》 2012年第11期656-662,共7页
In recent years, tighter regulation has been already enforced on harmful substances such as NOx, CO, and particles. Considering the above situation, it is important to monitor controlling factors of engine systems in ... In recent years, tighter regulation has been already enforced on harmful substances such as NOx, CO, and particles. Considering the above situation, it is important to monitor controlling factors of engine systems in order to improve efficiencies of their operations. As to car engines, an increasing concern in environmental issues such as air pollution, global warming and petroleum depletion has helped drive researches into various ways. Laser diagnostics has been applied to measure species concentration in the actual industrial fields. However there are several challenges to proceed in applying laser diagnostics to practical application. Especially stability of the measurement system is one of the most difficult issues. The purpose of this research is the development of a prompt measurement technique which can be applicable to various engine conditions. The Tunable Diode Laser Absorption Spectroscopy (TDLAS) using the hollow fiber has been developed to satisfy above requirements. By using a hollow fiber, misalignment of an optical axis and vulnerability of measurement environment such as vibration can be greatly reduced with sensitive and fast response features. It was demonstrated that this method can be applicable to measure gas compositions in engine exhaust with a range of millisecond response time. A sensitive method using tunable UV diode laser absorption spectroscopy was also discussed to detect NOx in exhausts. 展开更多
关键词 Tunable diode laser absorption spectroscopy optical hollow fiber exhaust gas concentration measurement.
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