期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
强激光质子束透视成像应用于肿瘤细胞异型性分析的探索研究 被引量:4
1
作者 王光昶 张建炜 郑志坚 《中国医学物理学杂志》 CSCD 2010年第2期1777-1780,共4页
目的:为了探索强激光质子束透视成像在肿瘤细胞异型性分析的应用研究,在皮秒超强脉冲激光装置上,进行皮秒激光-固体靶相互作用中产生的高能质子束透视生物样品成像的实验研究。方法:实验是在俄罗斯的皮秒超强激光装置上进行的,实验中以... 目的:为了探索强激光质子束透视成像在肿瘤细胞异型性分析的应用研究,在皮秒超强脉冲激光装置上,进行皮秒激光-固体靶相互作用中产生的高能质子束透视生物样品成像的实验研究。方法:实验是在俄罗斯的皮秒超强激光装置上进行的,实验中以小生物蚂蚁作为样品,用皮秒激光脉冲辐照固体靶,在靶背表面产生高能质子束透视生物样品成像。实验所用激光能量为12J、脉宽为1.5ps、焦斑直径(FWHM)为15μm、离轴抛物面透镜的光学f数为1.5。产生质子束的靶为15μm的铜膜后衬1μm的CH膜,质子源(激光光斑)距蚂蚁样品为7mm(又称物距),蚂蚁距辐射变色膜为63mm(又称像距),文中所示记录底片(探测器)是辐射变色膜(RCF)或核固体径迹探测器(CR-39)堆叠。结果:获得了高对比度、空间分辨率为微米量级、视场适中、具有密度分辨能力的二维直观蚂蚁透视图像。结论:蚂蚁透视图像为探索强激光质子束透视成像在肿瘤细胞异型性分析的应用提供了可能性。 展开更多
关键词 激光质子束 透视成像 肿瘤细胞 异型性分析
下载PDF
强激光质子束应用于生物组织透视成像的研究 被引量:2
2
作者 王昌军 彭永进 +4 位作者 刘玉玲 王光昶 梁栋 张建炜 郑志坚 《中国激光医学杂志》 CAS 2017年第3期117-120,175,共5页
目的肿瘤细胞异型性的准确识别是恶性肿瘤得到早期发现、确诊和治疗的关键。本文提出一种"利用强激光质子束对细胞样品透视成像技术"观测肿瘤细胞异型性的新途径,并以蚂蚁作为生物样本进行初步观察。方法基于上述质子透视成... 目的肿瘤细胞异型性的准确识别是恶性肿瘤得到早期发现、确诊和治疗的关键。本文提出一种"利用强激光质子束对细胞样品透视成像技术"观测肿瘤细胞异型性的新途径,并以蚂蚁作为生物样本进行初步观察。方法基于上述质子透视成像技术,拟使用FLUKA蒙特卡罗(Monte Carlo,MC)程序,依据强激光质子束的特点,对质子透视成像进行定量的模拟研究,分析影响质子透视成像的主要因素,并以蚂蚁作为样品,用皮秒激光脉冲辐照固体靶,在靶背表面产生高能质子束透视生物样品成像。结果实验测量得到了三种质子束空间分布,圆盘结构、中心成丝结构和环状结构。通过实验验证可获取清晰的,视场适中可达mm级,空间分辨适中可达1μm,并具有密度分辨力的二维蚂蚁透视图像。结论强激光质子束透视成像具有较好的视场,较高的对比度,适合的空间和密度分辨力的二维透视图像,为肿瘤细胞分析上的应用提供了可能性。 展开更多
关键词 肿瘤细胞异型性 激光质子束 质子透视成像 细胞早期变异
原文传递
基于SiC材料的激光加速质子束辐照特性研究
3
作者 周丹晴 李东彧 +10 位作者 陈艺 李越 杨童 程浩 吴旻剑 李昱泽 晏炀 夏亚东 林晨 颜学庆 赵子强 《北京大学学报(自然科学版)》 EI CAS CSCD 北大核心 2022年第3期405-411,共7页
通过辐照核能材料SiC,表征激光加速质子束连续宽能谱、短脉冲和高瞬态流强的特点。将SiC样品放置在距离靶体4 cm处,连续进行300发满足指数能谱分布的能量为1~4.5 MeV的激光加速宽能谱连续质子束辐照。表面和截面拉曼光谱显示辐照后的Si... 通过辐照核能材料SiC,表征激光加速质子束连续宽能谱、短脉冲和高瞬态流强的特点。将SiC样品放置在距离靶体4 cm处,连续进行300发满足指数能谱分布的能量为1~4.5 MeV的激光加速宽能谱连续质子束辐照。表面和截面拉曼光谱显示辐照后的SiC散射峰强度减小,且拉曼光谱截面测量的整体趋势可以与SRIM模拟的能谱加权后的深度能损分布对应,从而通过实验对能量连续分布的激光加速质子束进行表征。此外,实验结果显示,激光加速质子束的短脉冲特性可在SiC表面产生相当高的瞬时束流密度。这种快速的宽能谱辐照为模拟反应堆中子辐照提供了可能性。 展开更多
关键词 激光加速质子 SIC 宽能谱 拉曼截面测量 短脉冲
下载PDF
Proton Beam Generated by Multi-Lasers Interaction with Rear-Holed Target
4
作者 杨鹏 范大鹏 李玉晓 《Communications in Theoretical Physics》 SCIE CAS CSCD 2017年第3期322-326,共5页
Multi-lasers are proposed to enhance the proton acceleration in laser plasma interaction. A rear-holed target is illuminated by three lasers from different directions. The scheme is demonstrated by two-dimensional par... Multi-lasers are proposed to enhance the proton acceleration in laser plasma interaction. A rear-holed target is illuminated by three lasers from different directions. The scheme is demonstrated by two-dimensional particlein-cell simulations. The electron cloud shape is controlled well and the electron density is improved significantly. The electrons accelerated by the three lasers induce an enhanced target normal sheath acceleration(TNSA) which suppresses the proton beam divergence and improves the maximum proton energy. The maximum proton energy is 22.9 Me V, which increased significantly than that of a single-laser target interaction. Meanwhile, the average divergence angle(22.3?) is reduced. The dependence of the proton beam on the length of sidewall is investigated in detail and the optimal length is obtained. 展开更多
关键词 PIC simulation proton acceleration rear-holed target multi-lasers
原文传递
Study of metamorphic InGaAs/GaAs quantum well laser materials grown on GaAs substrate by molecular beam epitaxy
5
作者 朱岩 倪海桥 +4 位作者 王海莉 贺继方 李密峰 尚向军 牛智川 《Optoelectronics Letters》 EI 2011年第5期325-329,共5页
The GaAs based InGaAs metamorphic structures and their growth by molecular beam epitaxy (MBE) are investigated. The controlling of the source temperature is improved to realize the linearly graded InGaAs metamorphic s... The GaAs based InGaAs metamorphic structures and their growth by molecular beam epitaxy (MBE) are investigated. The controlling of the source temperature is improved to realize the linearly graded InGaAs metamorphic structure precisely. The threading dislocations are reduced. We also optimize the growth and annealing parameters of the InGaAs quantum well (QW). The 1.3-μm GaAs based metamorphic InGaAs QW is completed. A 1.3-μm GaAs based metamorphic laser is reported. 展开更多
关键词 Epitaxial growth Gallium arsenide Growth (materials) Molecular beam epitaxy Semiconducting gallium Semiconducting indium Semiconductor quantum wells
原文传递
Fusion Energy and Stopping Power in a Degenerate DT Pellet Driven by a Laser-Accelerated Proton Beam
6
作者 M.Mehrangiz A.Ghasemizad +1 位作者 S.Jafari B.Khanbabaei 《Communications in Theoretical Physics》 SCIE CAS CSCD 2016年第6期761-766,共6页
In this paper, we have improved the fast ignition scheme in order to have more authority needed for highenergy-gain. Due to the more penetrability and energy deposition of the particle beams in fusion targets, we empl... In this paper, we have improved the fast ignition scheme in order to have more authority needed for highenergy-gain. Due to the more penetrability and energy deposition of the particle beams in fusion targets, we employ a laser-to-ion converter foil as a scheme for generating energetic ion beams to ignite the fusion fuel. We find the favorable intensity and wavelength of incident laser by evaluating the laser-proton conversion gain. By calculating the source-target distance, proton beam power and energy are estimated. Our analysis is generalized to the plasma degeneracy effects which can increase the fusion gain several orders of magnitude by decreasing the ion-electron collisions in the plasma.It is found that the wavelength of 0.53 μm and the intensity of about 1020W/cm^2, by saving about 10% conversion coefficient, are the suitable measured values for converting a laser into protons. Besides, stopping power and fusion burn calculations have been done in degenerate and non-degenerate plasma mediums. The results indicate that in the presence of degeneracy, the rate of fusion enhances. 展开更多
关键词 proton fast ignition degenerate plasma laser-to-proton converter foil stopping power
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部