盘式电流变减速器的设计

基于电流变效应原理,设计盘式电流变减速器.论述盘式电流变减速器的工作原理、结构特点、计算方法、调速性能,以及各主要参数对盘式电流变无极减速器中的影响.试验表明,电流变减速器具有柔性接入、离合简单、无极调速、动态调整、响应迅速和控制简单等良好品质.

PTEN和BID在宫颈癌组织中的表达及意义

目的:探讨磷酸酶张力蛋白同系物(PTEN)和BH3相互作用结构域死亡激动剂(BID)在宫颈癌发病机制中的作用。方法:选取宫颈癌患者107例,取癌组织(宫颈癌组),并与50例宫颈上皮内瘤变(宫颈上皮内瘤变组)、慢性宫颈炎(慢性宫颈炎组)作对照,免疫组化法检测PTEN和BID的表达。结果:宫颈癌组PTEN和BID的阳性率和阳性表达强度(分别为:42.99%,OD值:0.19±0.04;45.79%,OD值:0.17±0.02)显著低于宫颈上皮内瘤变组(分别为:62.00%,OD值:0.22±0.05;74.00%,OD值:0.20±0.04)和慢性宫颈炎组(分别为:66.00%,OD值:0.23±0.05;82.00%,OD值:0.22±0.04)(P<0.05或P<0.01)。宫颈上皮内瘤变组和慢性宫颈炎组PTEN和BID的阳性率和阳性表达强度差异均无统计学意义(均P>0.05)。在宫颈癌组中,伴有淋巴结转移组BID的阳性率和阳性表达强度(33.33%;OD值:0.16±0.02)均低于不伴有淋巴结转移组(63.16%;OD值:0.18±0.02)(均P<0.05);PTEN的阳性率和阳性表达强度在伴或不伴淋巴结转移时差异均无统计学意义(38.89%vs 47.37%;OD值:0.19±0.03 vs0.21±0.05)(均P>0.05)。结论:PTEN和BID在宫颈癌组织中表达下降,它们可能与宫颈癌的恶性分化有关,BID的表达还与淋巴结转移相关。PTEN和BID可能是一种治疗肿瘤的潜在靶点。

A 10 Gb/s laser diode driver in 0.35 μm SiGe BiCMOS technology

This paper discusses the design of a 10 Gb/s laser diode driver implemented in SiGe BiCMOS technology. The laser diode driver is composed of an input buffer, a predriver circuit and an output current switch stage. With the current mode logic （CML） structure, the input buffer and the predriver circuit have the capability of transmission and amplification of high speed data. By employing MOS-HBT cascode structure as the output stage, the laser diode driver exhibits very high speed and efficiency working at the 10 Gb/s data rate. The core circuit is operated under a 3. 3 V supply, while the output stage is operated under 5.5 V for sufficient headroom across the laser diode. The chip occupies a die area of 600 μm × 800μm. Measurements on chip show clear electrical eye diagrams over 10 Gb/s, which can well meet the specifications defined by SDH STM64/SONET OC192 and a 10 Gb/s Ethemet eye mask. Under a 5. 5 V supply voltage, the maximum output swing is 3.0 V with a 50 12 load （the corresponding modulation current is 60 mA）, and the total power dissipation is 660 mW.

Transient response of piles-bridge under horizontal excitation

Moving ships and other objects drifting on water often impact a bridge' s pile foundations. The mechanical model of the piles-bridge structure under horizontal forcing was established, and a time-domain approach based on Finite-difference Method was developed for analyzing the dynamic response of the piles-bridge structure. For a single pile, good agreement between two computed results validated the present approach.The slenderness ratio of the pile, the pile-soil stiffness ratio and the type of the structure influence the dynamic response of the piles-bridge structure. The computed results showed that the stiffness of the structure determines the dynamic response of the piles-bridge structure under horizontal forcing.

Resonance Raman Spectroscopic and Theoretical Study of Geometry Distortion of Thiourea in 2^1A State

The A-band resonance Raman spectra of thiourea were obtained in water and acetonitrile solution. B3LYP/6-311＋＋G（3df,3pd） and RCIS/6-311＋＋G（3df,3pd） calculations were done to elucidate the ultraviolet electronic transitions, the distorted geometry structure and the saddle point of thiourea in 21A excited state, respectively. The resonance Raman spectra were assigned. The absorption spectrum and resonance Raman intensities were modeled using Heller＇s time-dependent wavepacket approach to resonance Raman scattering. The results indicate that largest change in the displacement takes place with the C--S stretch mode u6 （｜△｜=0.95） and noticeable changes appear in the H5N3H6＋H8N4H7 wag v5 （｜△｜=0.19）, NCN symmetric stretch^-C--S stretch＋N3H6＋H8N4 wag v4 （｜△｜=0.18）, while the moderate intensities of 2-15 and 4-15 are mostly due to the large excited state frequency changes of v15, but not due to its significant change in the normal mode displacement. The mechanism of the appearance of even overtones of the S-CN2 out of plane deformation is explored. The results indicate that a Franck-Condon region saddle point is the driving force for the quadric phonon mechanism within the standard A-term of resonance Raman scattering, which leads to the pyramidalization of the carbon center and the geometry distortion of thiourea molecule in 21A excited state.

Structural Dynamics of 3-Dimethylamino-2-methyl-propenal in S2（ππ^＊） State

The photophysics of 3-dimethylamino-2-methyl-propenal （DMAMP） after excitation to the S2 （ππ^＊） electronic state was studied using the resonance Raman spectroscopy and complete active space self-consistent field method calculations. The transition barriers of the ground state tautomerization reactions between DMAMP and its three isomers were determined at B3LYP/6-311＋＋G（d,p） level of theory. The vibrational spectra were assigned. The A- band resonance Raman spectra were obtained in acetonitrile with excitation wavelengths in resonance with the first intense absorption band to probe the structural dynamics of DMAMP. The B3LYP-TD computation was carried out to determine the relative A-band resonance Raman intensities of the fundamental modes, and the result indicated that the vibronic-coupling existed in Franck-Condon region. Complete active space self-consistent field （CASSCF） calculations were carried out to determine the excitation energies of the lower-lying singlet and triplet excited states, the conical intersection points and the intersystem crossing points. The A-band short-time structural dynamics and the corresponding decay dynamics of DMAMP were obtained by analysis of the resonance Raman intensity pattern and CASSCF computations. It was found that a sudden de-conjugation between C1=O6 and C2=C3 occurred at the Franck-Condon region of the S2（ππ^＊） state, while the enhancement of the conjugation interaction between C3 and N（CH3）2, and between C1 and C2 evolutions shortly after the wavepacket leaves away the Pranck-Condon region via the excited state charge redistribution. The de-conjugation interaction between C1=O6 and C2=C3 made the rotation of C3=N（CH3）2 group around the C2-C3 bond much easier, while the enhanced conjugation between C1 and C2, and between C3 and N（CH3）2 made the rotation around the C1-C2 bond and C3-N5 more difficult. It was revealed that the initial structural dynamics of DMAMP was predominantly towards the CI-I（S2/S0） point, while the opportunities towards either CI-2（S2/S0） or CI-3（S2/S0） point were negligible. Two decay channels of DMAMP from S2,FC（ππ^＊） to So or Tl,min via various CIs and ISCs were proposed.

Ultrafast Infrared Spectroscopic Study of Microscopic Structural Dynamics in pH Stimulus-Responsive Hydrogels

Hydrogels show versatile properties and are of great interest in the fields of bioelectronics and tissue engineering.Understanding the dynamics of the water molecules trapped in the three-dimensional polymeric networks of the hydrogels is crucial to elucidate their mechanical and swelling properties at the molecular level.In this report,the poly(DMAEMA-co-AA)hydrogels were synthesized and characterized by the macroscopic swelling measurements under different pH conditions.Furthermore,the microscopic structural dynamics of pH stimulus-responsive hydrogels were studied using FTIR and ultrafast IR spectroscopies from the viewpoint of the SCN-anionic solute as the local vibrational reporter.Ultrafast IR spectroscopic measurements showed the time constants of the vibrational population decay of SCN-were increased from 14±1 ps to 20±1 ps when the pH of the hydrogels varied from2.0 to 12.0.Rotational anisotropy measurements further revealed that the rotation of SCNanionic probe was restricted by the three-dimensional network formed in the hydrogels and the rotation of SCN-anionic probe cannot decay to zero especially at the pH of 7.0.These results are expected to provide a molecular-level understanding of the microscopic structure of the cross-linked polymeric network in the pH stimulus-responsive hydrogels.

Operational Modal Analysis of a Ship Model in the Presence of Harmonic Excitation

A ship is operated under an extremely complex environment, and waves and winds are assumed to be the stochastic excitations. Moreover, the propeller, host and mechanical equipment can also induce the harmonic responses. In order to reduce structural vibration, it is important to obtain the modal parameters information of a ship. However, the traditional modal parameter identification methods are not suitable since the excitation information is difficult to obtain. Natural excitation technique-eigensystem realization algorithm （NExT-ERA） is an operational modal identification method which abstracts modal parameters only from the response signals, and it is based on the assumption that the input to the structure is pure white noise. Hence, it is necessary to study the influence of harmonic excitations while applying the NExT-ERA method to a ship structure. The results of this research paper indicate the practical experiences under ambient excitation, ship model experiments were successfully done in the modal parameters identification only when the harmonic frequencies were not too close to the modal frequencies.

Nonlinear analysis of pounding between decks of multi-span bridge subjected to multi-support and multi-dimensional earthquake excitation

The nonlinear analysis of pounding between bridge deck segments subjected to multi-support excitations and multi-dimensional earthquake motion was performed.A novel bottom rigid element(BRE)method of the current displacement input model for structural seismic analysis under the multi-support excitations was used to calculate structural dynamic response.In the analysis,pounding between adjacent deck segments was considered.The seismic response of a multi-span bridge subjected to the multi-support excitation,considering not only the traveling-wave effect and partial coherence effect,but also the seismic non-stationary characteristics of multi-support earthquake motion,was simulated using finite element method(FEM).Meanwhile,the seismic response of the bridge under uniform earthquake was also analyzed.Finally,comparative analysis was conducted and some calculation results were shown for pounding effect,under multi-dimensional and multi-support earthquake motion,when performing seismic response analysis of multi-span bridge.Compared with the case of uniform/multi-support/multi-support and multi-dimensional earthquake input,the maximum values of pounding force in the case of multi-support and multi-dimensional earthquake input increase by about 5 8 times;the absolute value of bottom moment and shear force of piers increase by about50%600%and 23.1%900%,respectively.A conclusion can be given that it is very necessary to consider the pounding effect under multi-dimensional and multi-support earthquake motion while performing seismic response analysis of multi-span bridge.

Impact of Structural Disorder on Excitonic Behaviors and Dynamics in 2D Organic-Inorganic Hybrid Perovskites

Two thin-film 2 D organic-inorganic hybrid perovskites,i.e.,2-phenylethylammonium lead iodide(PEPI)and 4-phenyl-1-butylammonium lead iodide(PBPI)were synthesized and investigated by steady-state absorption,temperature-dependent photoluminescence,and temperature-dependent ultrafast transient absorption spectroscopy.PBPI has a longer organic chain(via introducing extra ethyl groups)than PEPI,thus its inorganic skeleton can be distorted,bringing on structural disorder.The comparative analyses of spectral profiles and temporal dynamics revealed that the greater structural disorder in PBPI results in more defect states serving as trap states to promote exciton dynamics.In addition,the fine-structuring of excitonic resonances was unveiled by temperature-dependent ultrafast spectroscopy,suggesting its correlation with inorganic skeleton rather than organic chain.Moreover,the photoexcited coherent phonons were observed in both PEPI and PBPI,pointing to a subtle impact of structural disorder on the low-frequency Raman-active vibrations of inorganic skeleton.This work provides valuable insights into the optical properties,excitonic behaviors and dynamics,as well as coherent phonon effects in 2 D hybrid perovskites.

Semi-active predictive control strategy for seismically excited structures using MRF-04K dampers

The theoretical study of a semi-active predictive control(SAPC) system with magnetorheological(MR) dampers to reduce the responses of seismically excited structures was presented.The SAPC scheme is based on a prediction model of the system response to obtain the control actions by minimizing an object function,which has a function of self-compensation for time delay occurring in real application.A double-ended shear mode combined with a valve mode MR damper,named MRF-04K damper,with the maximum force of 20 kN was designed and manufactured,and parameters of the Bouc-Wen hysteresis model were determined to portray the behavior of this damper.As an example,a 5-story building frame equipped with 2 MRF-04K dampers was presented to demonstrate the performance of the proposed SAPC scheme for addressing time delay and reducing the structural responses under different earthquakes.Comparison with the uncontrolled structure,the passive-off and passive-on cases indicates that both the peak and the norm values of structural responses are all clearly reduced,and the SAPC scheme has a better performance than the two passive cases.

Ultrafast Electron Diffraction with Spatiotemporal Resolution of Atomic Motion

Ultrafast electron diffraction （UED） is a rapidly advancing technique capable of recording the atomic-detail structural dynamics in real time. We report the establishment of the first UED system in China. Employing this UED apparatus, both the coherent and the concurrent thermal lattice motions in an aluminium thin-film, trigged by ultrafast laser heating, have been observed. These results demonstrate its ability to directly measure a sub-milli-angstrom lattice spacing change on a sub-picosecond time scale.

An Application of Damage Detection Methods to A Real World Structure Subjected to Ground Motion Excitation

This paper aims at investigating the efficacy of different state-of-art damage detection methods when applied to real worm structures subjected to ground motion excitations, for which the literature contributions are, at present, still not fully comprehensive. To this purpose the paper analyses two test structures： （1） a four-story scaled steel frame tested on a shake table in a controlled laboratory conditions, and （2） a seven-story reinforced concrete building monitored during the seismic excitations of the 1999 Chi-Chi （Taiwan） Earthquake main shock and numerous fore and afiershocks. Some model based damage approaches and statistics based damage indexes are reviewed. The different methodologies and indexes are, then, applied to the two test structures with the final aim of analysing their performance and validity within the case of a laboratory scaled model and a real world structure subjected to input ground motion.

Application of fiber Bragg grating based strain sensor in pipeline vortex-induced vibration measurement

The vortex-induced vibrations(VIV)is an important topic of study in many different scientific and engineering fields.While VIV can be of benefit in some cases,oftentimes,it is an undesirable phenomenon that can be quite dangerous.In particular for offshore pipelines,VIV can lead to fatiguing of the pipe structure and can cause disastrous consequences if left unchecked.A number of different methods have been applied to the measurement of VIV,especially for the elongated,thin cylindrical structures.The use of fiber optic fiber Bragg gratings(FBGs)in particular has gained popularity over the recent years due to their distinct properties.However,FBGs are also very fragile and are susceptible to failure when placed in harsh environments without protection.In this paper,56 FBGs encapsulated in stainless steel tubes were applied to the measurement of VIV in a28-m model pipeline under controlled and uncontrolled conditions.Tests show that the encapsulated sensors possessed good sensitivity as well as fatigue life(>80000 cycles).The measurements from FBGs were also high enough to allow frequency domain analysis of the pipeline VIV under the two conditions.The authors conclude that the encapsulated FBGs are a viable tool for the study of VIV in pipeline structures.

Bifurcation analysis for vibrations of a turbine blade excited by air flows

A reduced three-degree-of-freedom model simulating the fluid-structure interactions （FSI） of the turbine blades and the on- coming air flows is proposed. The equations of motions consist of the coupling of bending and torsion of a blade as well as a van der Pol oscillation which represents the time-varying of the fluid. The 1：1 internal resonance of the system is analyzed with the multiple scale method, and the modulation equations are derived. The two-parameter bifurcation diagrams are computed. The effects of the system parameters, including the detuning parameter and the reduced frequency, on responses of the struc- ture and fluid are investigated. Bifurcation curves are computed and the stability is determined by examining the eigenvalues of the Jacobian matrix. The results indicate that rich dynamic phenomena of the steady-state solutions including the sad- dle-node and Hopf bifurcations can occur under certain parameter conditions. The parameter region where the unstable solu- tions occur should be avoided to keep the safe operation of the blades. The analytical solutions are verified by the direct nu- merical simulations.

Strength behavior and collapse of spatial-reticulated structures under multi-support excitation

Under strong shocks,long-span spatial-latticed structures may collapse due to dynamic instability or strength failure.The elasto-plastic dynamic behaviors of three spatiallatticed structures,including two double-layer cylindrical shells and a spheri-cal shell used for the 2008 Olympic Games in Beijing,were quantitatively examined under multi-support excitation(MSE) and uniform support excitation(USE).Numerical analyses described several important parameters such as the peak acceleration and displacement responses at key joints,the number and distribution of plastic elements,and the deformation of the shell at the moment of collapse.Results of the analysis revealed the features and the failure mechanism of the spatial-latticed structures under MSE and USE.In both scenarios,the double-layer reticulated shell collapsed in the "overflow" mode,collapse was govrned by the number of invalid plastic elements rather than the total number of plastic elements,and the collapse of the structure began with damage to certain local regions near the supports.By comparing the numbers and distributions of the plastic members under MSE to those under USE,it was observed that the plastic members spread more sufficiently and the internal forces were more uniform under MSE,especially for lower apparent velocities in soils.Due to the effects of pseudo-static displacement,the stresses in members near supports under MSE were higher than those under USE.These regions are prone to failure during earthquakes and deserve special attention in the seismic design of reticulated structures.

Suppression of vortex-induced vibration of a circular cylinder by Lorentz force

The electro-magnetic control of vortex-induced vibration (VIV) of a circular cylinder is investigated numerically in the exponential-polar coordinates attached on the moving cylinder for Re=150 in the paper. Compared with the fixed cylinder, the vibration of cylinder leads to the shift of stagnation point, the shear layer strength and the inertial force, which affects the hydrodynamic forces on the cylinder. The effects of the instantaneous wake geometries and the corresponding cylinder motion on the hydrodynamic forces for one entire period of vortex shed are discussed in the drag-lift phase diagram. The Lorentz force for controlling the vibration cylinder is classified into the field Lorentz force and the wall Lorentz force. The field Lorentz force decreases the lift oscillation, and in turn, suppresses the VIV, whereas the wall Lorentz force has no effect on the lift.

A full-length 3D structure for MAPK/ERK kinase 2 (MEK2)

As a pivotal signal pathway,the Ras/Raf/MEK/ERK cascade can be activated by multiple extracellular stimuli and can transmit signals to diverse substrates.It remains to be elucidated how so many different signals can be variously transferred by only two MEK molecules(MEK1 and MEK2) .Because of technological limitations the complete structures of the MEKs are still unavailable.Here,we report the full-length structure of MEK2 obtained by homology modeling and molecular dynamics simulations.The simulations show that the N-terminal part of MEK2 is highly flexible and this flexibility may enable MEK2 to interact with ERKs and other ligands in diverse manners that correspond to various upstream signals and downstream consequences.

Deformation analysis of the flexspline of harmonic drive gears considering the driving speed effect using laser sensors

Accurate description of the elastic deformation of the flexspline is the foundation for optimization design of the structure and conjugate profiles of the harmonic drive gear. This paper proposed an experimental method to investigate the effect of the driving speed on the deformation characteristics of the flexspline. First, an experimental apparatus that integrates a special-fabricated micro-displacement platform and a pair of laser displacement sensors is developed, and the radial displacement of the flexspline is measured in vertical and horizontal directions. Next, the deformation analyses of the flexspline at different driving speeds are performed with our method and the conventional method, and the comparison results reveal that the radial displacement of the flexspline is actually composed of both harmonic and random components, and the amplitude decreases and tends to zero with the increase of the driving speed, especially near the closed end of the flexspline. Last, the mechanisms of the inherent multi-frequency and amplitude attenuation characteristics of the radial displacement of the flexspline are discussed. It is indicated that the impact and friction existing in the flexible bearing of the wave generator is likely responsible for the existence of the random component, and the assumption of linear distribution of the ftexspline deformation along the rotating axis is invalid under high speed condition. Our research promotes the further study on the contact-impact problem of the flexible bearing of the wave generator and the transfer characteristic of the elastic deformation of the flexspline.

Liquid spreading on a pre-wetted biomimetic surface inspired by a dog's tongue

Liquid film flow widely exists in industries due to its high thermal film is strongly influenced by the properties of the working surface efficiency and low flow flux. The spreading of the liquid A biomimetic surface with multi-scale structures inspired by the skin of a dog＇s tongue is proposed in this paper for the enhancement of heat and mass transfer. The spreading and flow behaviors of a gravity-driven liquid falling down the pre-wetted biomimetic surface are compared with that on the smooth sur- faces, via the combination of numerical simulations using the volume of fluid （VOF） method, and experimental measurements using high-speed imaging. On the pre-wetted smooth substrate, liquid merges with two droplets before the free surface of the liquid slowly develops into a parabolic shape. In contrast, on the biomimetic surface, liquid rapidly and uniformly spreads into a thin film which could effectively enhance mass transfer in both spanwise and streamwise directions. The characteristics and distribution of the microstructures on the proposed biomimetic surface are potentially to be used to guide the design of the surface in high efficiency heat exchangers and reactors.