简式行为抑制/激活量表中文版的信效度检验

目的对简式行为抑制/激活量表(Brief Behavioral Inhibition/Activation Scales,BBIS/BAS)中文版的信度和效度进行检验。方法用BBIS/BAS中文版对340名中学生和371名大学生施测,同时测定S-UPPS-P冲动行为量表及简式网络游戏障碍量表(IGD9-SF)作为效标效度的检测。随机在受试者中抽选100名被试于四周后实施重测。结果探索性因素分析表明结构为三维度,验证性分析显示结构效度优,拟合度指标如下:χ^(2)为32.75,χ^(2)/df为1.36;CFI为0.99,TLI为0.94,RMSEA为0.03,SRMR为0.03。项目分析结果表明,各条目具有良好区分度,同时各条目在得分上与所属分量表和总量表均呈显著相关(r为0.48~0.91,P<0.001)。BBIS/BAS中文版总量表和三个分量表的α系数为0.63~0.88;重测信度为0.73~0.81。BBIS/BAS量表总分及三个维度得分与S-UPPS-P总量表分及其五个维度分以及IGD9-SF总分均存在显著性相关(r=0.12~0.56,P<0.001)。结论简式行为抑制/激活量表中文版的信效度检验结果良好,可以作为有效的心理测量工具以研究对奖赏性刺激和惩罚性刺激的敏感性问题。

抑郁症行为激活量表中文版在美沙酮维持治疗患者中的应用

目的:评价抑郁症行为激活量表中文版(the Chinese version of behavioral activation for depression scale,C-BADS)应用于美沙酮维持治疗(methadone maintenance treatment,MMT)患者的信度和效度。方法:在武汉市MMT门诊随机招募162例阿片类物质成瘾患者接受C-BADS量表调查,采用SPSS 21.0软件进行项目分析和探索性因子分析(exploratory factors analysis,EFA),AMOS 24.0软件进行验证性因子分析(confirmatory factor analysis,CFA)。结果:各维度与总分之间的相关系数为0.228~0.813(均P<0.01),除激活维度外,其余各维度间的相关系数均低于各维度与总分之间的相关系数。各条目与总分之间的相关系数为0.060~0.716。探索性因子分析提取了4个公因子,分别命名为回避/沉思(avoidance/rumination,AR)、激活(activation,AC)、社会功能减退(social impairment,SI)和工作/学习功能减退(work/school impairment,WS),对总方差的累积贡献率为51.153%,各条目在所属因子上的因子负荷为0.328~0.797。验证性因子分析模型的整体拟合度指标为:χ^(2)/df=1.594,CFI=0.839,TLI=0.820,IFI=0.844,RMSEA=0.069,SRMR=0.089。量表内部一致性信度Cronbach'sα系数为0.790,分半信度为0.827。结论:C-BADS用于测量MMT患者行为激活状况具有较好的内部一致性信度和结构效度,但仍需要进一步修改。

城市有机垃圾厌氧消化痕量激活剂的促进作用及产能研究

城市有机垃圾厌氧消化处理相对其它处理方法而言是一种具有广阔应用前景的垃圾资源化方法,它能充分利用其含有的生物质能.本文研究了痕量金属Fe、Co、Ni对产甲烷菌的激活作用.以有机生活垃圾为基质,进行干式中温厌氧消化,对比研究结果表明:在其他条件相同的情况下,投加痕量金属离子比不投加的系统产气量增加了43.4%,生物气的甲烷含量提高了5.1%,COD去除率提高了10.2%.同时,它还有利于缩短停留时间并减小消化反应器的体积.

轴类零件加工相似性的可拓基元网络推理方法

工艺规划的实例推理方法,具有实例获取简单、工艺规划策略效率高的特点。提出利用实例推理的方法对轴类零件的相似性检索进行研究,利用可拓基元描述网络表述工艺相关的特征知识,并用可拓基元来描述与工艺的知识项,再对结构特征与精度特征量值的取值进行了分析。在此基础上,提出了基于激活量的可拓基元描述网络推理算法。最后,结合实例应用验证了提出的可拓基元描述网络实例推理算法的有效性。

改进的记忆认知启发机会网络社区检测方法

社区检测是研究网络结构的基础,在分析现有机会网络社区检测算法的基础上,提出一种改进的基于记忆的认知启发社区检测方法IMBC。节点通过记录与其它节点的历史接触信息,计算和其它节点的记忆激活量,通过约束处理,把记忆激活量在某一阈值范围的节点归入同一社区,完成网络社区的检测。进行随机生成网络仿真,与MBC算法性能进行比较,比较结果验证了该算法的有效性。

Energy expenditure and muscular activation patterns through active sitting on compliant surfaces

Purpose: To test the effectiveness of sitting surfaces with varied amounts of stability on muscle activity and energy expenditure.Methods: Using a within-participants repeated measures design, 11 healthy young-adult females(age = 20.0 ± 1.8 years) were measured using indirect calorimetry to assess energy expenditure, and electromyography to assess muscular activation in trunk and leg musculature under 3different sitting surfaces: flat-firm surface, air-filled cushion, and a stability ball. Data were analyzed using repeated measures analysis of variance with follow-up pairwise contrasts used to determine the specific effects of sitting surface on muscle activation and energy expenditure.Results: Significantly greater energy expenditure was recorded for the stability ball(p = 0.01) and the cushion(p = 0.03) over the flat surface(10.4% and 9.6% greater, respectively), with no differences between the ball and the cushion. Both the ball and the cushion produced higher tibialis anterior activation over the flat surface(1.09 and 0.63 root-mean-square millivolts(RMSmv), respectively), while the stability ball produced higher soleus activity over both cushion and flat surfaces(3.97 and 4.24 RMSmv, respectively). Additionally, the cushion elicited higher adductor longus activity over the ball and flat surfaces(1.76 and 1.81 RMSmv, respectively), but no trunk musculature differences were revealed.Conclusion: Compliant surfaces resulted in higher levels of muscular activation in the lower extremities facilitating increased caloric expenditure.Given the increasing trends in sedentary careers and the increases in obesity, this is an important finding to validate the merits of active sitting facilitating increased caloric expenditure and muscle activation.

行为激活抑制量表在中国军人群体中的应用分析

目的验证行为激活/抑制量表中文版在中国军人群体中的适用性，修订量表和建立因素模型。方法采用整群随机抽样方法，采用行为激活/抑制量表中文版（18题）对全国来自3个军区的2 921名军人开展调查，利用SPSS 22.0进行探索性因素分析，在固定和不固定因子数目两种情况下建立模型，在Amos 17.0中通过验证性因素分析验证模型的拟合效果。结果和Carver及White四因素模型，以及中国大学生四因素模型不同，中国军人行为激活/抑制系统符合三因素模型（行为抑制、奖赏反应性、驱力），修订后量表包括13个题项，模型拟合效果良好（KMO＝0.87，CFI＝0.94，RMSEA＝0.06），各分量表内部一致性信度Cronbach α系数分别是行为抑制0.78，驱力0.71，奖赏反应性0.67。其中行为抑制和驱力分量表内部一致性高于大学生四因素模型，驱力和奖赏反应性分量表内部一致性低于国外同年龄群体。行为抑制和驱力可以正向预测抑郁程度（βBIS＝0.332，βDrive＝0.076，P〈0.001），奖赏反应性可以反向预测抑郁程度（βRRS＝－0.140，P〈0.001）。结论中国军人行为激活/抑制量表三因素模型具有良好的信效度，可以作为中国军人趋近回避动机系统的测量工具。

Effect of Chemical Doping and Ion Implantation on Cond uctivity of Poly(p-phenylene vinylene) Derivatives

The surface conductivity of poly [ 2-methoxy-5-（3＇-methyl） butoxy]-p-phenylene vinylene （PMOMBOPV） films doped with FeCl3 and H2SO4 by chemical method and implanted by N^＋ ions was studied and the comparison of environmental stability of conductive behavior was also investigated. The energy and dose of N^＋ ions were in the rang 15～35 keV and 3. 8×10^15～9. 6×10^16 ions/cm^2, respectively. The conductivity of PMOMBOPV film was enhanced remarkably with the increases of the energy and dose of N^＋ ions. For example, the conductivity of PMOMBOPV film was 3. 2×10^-2S/cm when ion implantation was performed with an energy of 35 keV at a dose of 9. 6 × 10^14 ions/cm^2 , which was almost seven orders of magnitude higher than that of film unimplanted. The environmental stability of conductive behavior for ionimplanted film was much better than that of chemical doped films. Moreover, the conductive activation energy of ion-implanted films was measured to be about 0.17 eV.

Long acting octreotide in the treatment of advanced hepatocellular cancer and overexpression of somatostatin receptors: Randomized placebo-controlled trial

AIM: To estimate if and to what extent long acting octreotide (LAR) improves survival and quality of life in patients with advanced hepatocellular carcinoma (HCC). METHODS: A total of 127 cirrhotics, stages A-B, due to chronic viral infections and with advanced HCC, were enrolled in the study. Scintigraphy with 111Indium labeled octreotide was performed in all cases. The patients with increased accumulation of radionuclear compound were randomized to receive either oral placebo only or octreotide/octreotide LAR only as follows: octreotide 0.5mg s.c. every 8 h for 6 wk, at the end of wk 4-8 octreotide LAR 20 mg i.m. and at the end of wk 12 and every 4 wk octreotide LAR 30mg i.m.. Follow-up was worked out monthly as well as the estimation of quality of life (QLQ-C30 questionnaire). Patients with negative somatostatin receptors (SSTR) detection were followed up in the same manner. RESULTS: Scintigraphy demonstrated SSTR in 61 patients. Thirty were randomized to receive only placebo and 31 only octreotide. A significantly higher survival time was observed for the octreotide group (49 ± 6 wk) as compared to the control group (28 ± 1 wk) and to the SSTR negative group (28 ± 2 wk), LR = 20.39, df = 2, P < 0.01. The octreotide group presented 68.5% lower hazard ratio [95% CI (47.4%-81.2%)]. During the f irst year, a 22%, 39% and 43% decrease in the QLQ-C30 score was observed in each group respectively.CONCLUSION: The proposed therapeutic approach has shown to improve the survival and quality of life in SSTR positive patients with advanced HCC.

Active control of structural vibration by piezoelectric stack actuators

This paper presents a general analytical model of flexible isolation system for application to the installation of high-speed machines and lightweight structures. Piezoelectric stack actuators are employed in the model to achieve vibration control of flexible structures, and dynamic characteristics are also investigated. Mobility technique is used to derive the governing equations of the system. The power flow transmitted into the foundation is solved and considered as a cost function to achieve optimal control of vibration isolation. Some numerical simulations revealed that the analytical model is effective as piezoelectric stack actuators can achieve substantial vibration attenuation by selecting proper value of the input voltage.

Effect of selective uterine artery embolization on symptomatic uterine fibroids

Objective： To evaluate the outcomes of selective uterine artery embolization （SUAE） in treatment of symptomatic uterine fibroids using Color Doppler ultrasonography （CDUS）. Methods： As the procedure SUAE for fibroids, prospective data of the initial 65 consecutive women treated from March 2007 to September 2009 were collected. The follow-up period from 1 week to 30 months, using questionnaires, we investigated the fibroid-related physical and psychological symptoms, and the cumulative rates of symptom control, gynecologic interventions, and complications. The volumes of uterine and uterine fibroids were calculated by CDUS pre- and post-SUAE for 6 months. And we tested the levels of internal hormone including FSH, LH and E2 before and after SUAE for 3, 6 months. Results： SUAE was performed successfully in all patients. There was no peri-operative morbidity in all procedures. Compared with pre-SUAE volumes of uterine [（322± 12） cm^3] and uterine fibroids [（125±46） cm^3], their volumes in post-SUAE were （144±72） cm^3 and （51 a：l 1） cm^3 （P〈0.01）, and reduction rate was 58% and 61%, respectively. At 3, 6 months after SUAE, levels of FSH, LH, and E2 were not decreased than that of in pre-SUAE （P〉0.05）. After SUAE for 24 months, the fibroids related physical and psychological symptoms such as bleeding, pain and quality of life were significantly improved （P〈0.01）. 90.8% （59/65） women had resolution of symptoms and no significant post-procedural symptoms. Parts of patients discharge necrotic fibroids. 86% （34/40） complications were minor, requiring no therapy. 9.2% （6/65） had significant post-procedural symptoms, requiring therapy in hospital or out-patient department. Conclusion： SUAE contributes to a long-term significant improvement of all investigated uterine fibroid-related symptoms and markedly improves women＇s health-related quality of life. SUAE that no impair on changes of internal hormone, under suitable conditions, represents an attractive alternative to hysterectomy for the treatment of symptomatic fibroids and is a minimally invasive, new method of good clinical prognosis. CDUS is an effective to investigate the outcome of SUAE.

Mechanism and dose-effect of Ginkgolide B on severe acute pancreatitis of rats

AIM:To determine the optimal dosage and mechanism of Ginkgolide B(BN52021) on severe acute pancreatitis(SAP) of rats.METHODS:Seventy male Wistar rats were randomly divided into seven groups(10 for each group).Shamoperation group(SO),SAP model group(SAP),dimethyl sulfoxide(DMSO) contrast group(DMSO),and groups treated with 2.5 mg/kg BN52021(BN1),5 mg/kg BN52021(BN2),10 mg/kg BN52021(BN3),and 20 μg/kg Sandostatin(SS).The SAP model was established in Wistar rats by injecting 5% sodium taurocholate retrogradely into the common bilio-pancreatic duct.The rats of SO,DMSO and BN52021 were injected with 0.9% NaCl,0.5% DMSO and BN52021 through femoral vein 15 min after the operation.The SS group was injected with Sandostatin subcutaneously.All rats were anaesthetized at 6 h after operation,and venous blood was collected to determine the levels of serum amylase and phospholipase A2(PLA2),and pancreas tissue was harvested and stained.RESULTS:There was no significant difference between the SAP and DMSO groups in serum amylase level,PLA2,ascites and pathologic score,but significant difference was found in SAP/DMSO groups compared with those in SO group(P < 0.05) and the levels of serum amylase,PLA2,ascites,and pathologic score were lower in the BN1,BN2,BN3 and SS groups than in the SAP and DMSO groups(P < 0.05).However,among BN1,BN2,BN3 and SS groups,BN2 had the best effect in decreasing the levels of serum amylase and PLA2(P < 0.05).Expression of platelet activating factor(PAF) receptor(PAFR) mRNA and protein showed no significant difference between the SAP and DMSO groups,or among BN1,BN2,BN3 and SS groups,but there was remarkable difference between SAP/DMSO group and SO group(P < 0.05),and expression of PAFR mRNA and protein was higher in the BN1,BN2,BN3 and SS groups than in the SAP and DMSO groups(P < 0.05).PAFR expression was observed in the nucleus and cytoplasm of pancreatic islet cells in Wistar rats by immunohistochemistry.CONCLUSION:By iv injection,5 mg/kg of BN52021 is the optimal dosage for SAP rats.BN52021 may inhibit the interaction/binding of PAF with PAFR.

Fecal incontinence - Challenges and solutions

Fecal incontinence is not a diagnosis but a frequent and debilitating common final pathway symptom resulting from numerous different causes. Incontinence not only impacts the patient&#x02019;s self-esteem and quality of life but may result in significant secondary morbidity, disability, and cost. Treatment is difficult without any panacea and an individualized approach should be chosen that frequently combines different modalities. Several new technologies have been developed and their specific roles will have to be defined. The scope of this review is outline the evaluation and treatment of patients with fecal incontinence.

Energy-Efficient Joint Content Caching and Small Base Station Activation Mechanism Design in Heterogeneous Cellular Networks

Heterogeneous cellular networks(HCNs), by introducing caching capability, has been considered as a promising technique in 5 G era, which can bring contents closer to users to reduce the transmission delay, save scarce bandwidth resource. Although many works have been done for caching in HCNs, from an energy perspective, there still exists much space to develop a more energy-efficient system when considering the fact that the majority of base stations are under-utilized in the most of the time. Therefore, in this paper, by taking the activation mechanism for the base stations into account, we study a joint caching and activation mechanism design to further improve the energy efficiency, then we formulate the optimization problem as an Integer Linear Programming problem(ILP) to maximize the system energy saving. Due to the enormous computation complexity for finding the optimal solution, we introduced a Quantum-inspired Evolutionary Algorithm(QEA) to iteratively provide the global best solution. Numerical results show that our proposed algorithm presents an excellent performance, which is far better than the strategy of only considering caching without deactivation mechanism in the actual, normal situation. We also provide performance comparison amongour QEA, random sleeping algorithm and greedy algorithm, numerical results illustrate our introduced QEA performs best in accuracy and global optimality.

Dielectric properties and relaxation dynamics in PbF_2-TeO_2-B_2_O3-Eu_2O_3 glasses

Frequency and temperature dependent dielectric dispersion of 20PbF2？20TeO2？（60？x）B2O3？xEu2O3（x=0 to 2.5, mole fraction, %） glasses prepared by the melt？quenching technique were investigated in the frequency range 1 Hz？10 MHz and temperature range 313？773 K. Dielectric relaxation dynamics was analyzed based on the electric modulus behavior. Dielectric losses （tanδ） are found to be negligibly small in the temperature range 313？523 K, proving good thermal stability of the glasses. The present Eu2O3-doped oxyfluroborate glasses showed low dielectric loss at higher frequency and lower temperature, proving their suitability for nonlinear optical materials.

Improved sweat gland function during active heating in tennis athletes

Background：Relatively few studies on the peripheral sweating mechanisms of trained tennis athletes have been conducted.The purpose of this study was to compare the sweating capacities of tennis athletes against untrained subjects（controls）.Methods：Thirty-fi e healthy male volunteers participated including 15 untrained subjects and 20 trained tennis athletes（nationally ranked）.Active heat generation was performed for 30 min（running at 60%VO2max） in a climate chamber（temperature,25.0°C ± 0.5°C;relative humidity,60% ± 3%,termed active heating）.Sweating data（local sweat onset time,local sweat volume,activated sweat glands,sweat output per gland,whole body sweat loss volume） were measured by the capacitance hygrometer-ventilated capsule method and starch-iodide paper.Mean body temperature was calculated from tympanic and skin temperatures.Results：Local sweat onset time was shorter for tennis athletes（p〈0.001）.Local sweat volume,activated sweat glands of the torso and limbs,sweat output per gland,and whole body sweat loss volume were significant y higher for tennis athletes than control subjects after active heating（p〈0.001）.Tympanic and mean body temperatures were lower among tennis athletes than controls（p〈0.05）.Conclusion：These results indicate that tennis athletes had increased regulatory capacity of their sweat gland function.

Effect of vertebrate hormones and prostaglandins on growth, silk quality and metabolic activities of Bombyx mori L

The economic importance of silkworm has moved biologists to explore various intricate mechanisms of the action of vertebrate hormones. The dietary administration of several vertebrate hormones and prostaglandins enhanced both developmental and metabolic processes of silkworm, Bombyx mori L. The main objective of sericulture research is to apply the results to achieve superior quality silk and greater output, to apply lab findings to achieve desirable ecenomic results.

基于PEO模式的健康教育对老年脑卒中后抑郁患者焦虑抑郁水平和行为能力的影响

目的研究基于人-环境-作业(PEO)模式的健康教育对老年脑卒中后抑郁患者焦虑抑郁水平和行为能力的影响。方法选取2018年4月至2019年10月本院收治的老年脑卒中后抑郁患者125例,按照随机数字表法分为对照组62例和研究组63例。对照组给予正念减压疗法和康复功能训练,研究组在对照组的基础上增加基于PEO模式的健康教育。观察干预4_(w)后两组焦虑抑郁水平和行为能力。结果干预前,两组焦虑自评量表(SAS)评分、抑郁自评量表(SDS)、行为抑制系统量表(BIS)评分及行为激活系统量表(BAS)评分比较差异均无统计学意义(均P>0.05)。干预后,两组SAS评分和SDS评分均显著降低,BIS评分和BAS评分均显著升高,同时研究组改善明显优于对照组,差异均有统计学意义(均P<0.05)。结论基于PEO模式的健康教育能够显著缓解老年脑卒中后抑郁患者的焦虑抑郁水平,增强患者日常生活能力,全面提高行为能力。

Activated Sericite:An Efficient and Effective Natural Clay Material for Attenuation of Cesium from Aquatic Environment

Sericite is mica-based natural clay that is annealed at 800 ℃ for 4 h, followed by acid activation using 3.0 mol L-1HCl at 100℃. The interaction of cesium(I), Cs(I), with sericite could provide useful data for the study of soil erosion or mass water movement utilizing the natural radioactive Cs. In this study sericite and activated sericite were used to assess their suitability in the attenuation of Cs from the aquatic environment under both batch and column experiments. The surface morphological studies indicated that a disordered and heterogeneous surface structure was exhibited by the activated sericite, whereas the native sericite exhibited a compact and layered structure. The Brunauer-Emmett-Teller(BET) specific surface area results indicated a significant increase in the surface area due to the activation of sericite. The batch reactor data collected for various parametric studies revealed that an increase in p H(from 2.0 to 8.0) and sorbate concentration(from 10.0 to 100.0 mg L-1) apparently favored the attenuation of Cs(I). The timedependent sorption data revealed that Cs(I) uptake was very rapid, and it achieved its saturation value within just 50 min of contact.The kinetic modeling studies indicated that the uptake of Cs(I) followed a pseudo-second-order rate equation; hence, the attenuation capacity of these solids for Cs(I) was estimated to be 0.858 and 4.353 mg g-1for sericite and activated sericite solids, respectively.The adsorption isotherm modeling data showed a reasonably good applicability of the Freundlich model than the Langmuir model.The effect of background electrolyte concentrations(0.001 to 0.1 mol L-1) of Mg(NO3)2indicated that the presence of this electrolyte could not significantly affect the percent removal of Cs(I) by activated sericite. Furthermore, the fixed-bed column reactor operations were performed to obtain the breakthrough data, which were fitted well to the Thomas non-linear equation. Therefore, the loading capacity of Cs(I) was estimated to be 1.585 mg g-1at the initial influent Cs(I) concentration of 30.0 mg L-1at p H 5.0.

Effect of Yiqihuoxue prescription on myocardial energy metabolism after myocardial infarction via cross talk of liver kinase B1-depen-dent Notch1 and adenosine 5'-monophosphate-activated protein kinase

OBJECTIVE: To investigate the effect of Yiqihuoxue prescription(YQHX) from Traditional Chinese Medicine(TCM) on myocardial glucose and lipid metabolism after myocardial infarction via the cross talk between the liver kinase B1(LKB1)-dependent Notch1 and adenosine 5'-monophosphate(AMP)-activated protein kinase(AMPK). YQHX was prepared with substances with properties that benefit, to activate blood circulation based on the TCM theory.METHODS: Animal models of myocardial infarction were established by ligating Sprague Dawley rats' left anterior descending coronary arteries. The animals were randomly divided into a myocardial infarction(MI) group, a YQHX group, a perindopril group, a γ-secretase inhibitor, Notch signal inhibitor(DAPT) group, a DAPT+YQHX group and a sham group. The related drugs were administered on the second day after operation, and changes in the relevant indexes were examined on weeks 1 and 4.Changes in cardiac structure and function were examined by echocardiography. The glucose and free fatty acids(FFA) were examined by ELISA. The expression of Notch, LKB1 and AMPK m RNA was examined by a real-time fluorescence quantitative method. The expression of glucose transporter 4(GLUT4), and the expression of total acetyl-Co A carboxylase(ACC) and its phosphorylation were examined by western blotting.RESULTS: Compared with the sham group, the expression of Notch, LKB1 and AMPK m RNA in the MI group was lower. Compared with the MI group, the expression of these m RNAs in the YQHX and perindopril groups was higher, and their expression in the DAPT group was lower. At all time points, the protein expression of GLUT4 and p ACC decreased in the MI group. On week 1, the expression of p ACC protein was higher. In the DAPT group, the expression of p ACC protein decreased. Compared with the YQHX group, the expression of p ACC protein in the DAPT + YQHX group was lower. On week 4,compared with the MI group, the expression of GLUT4 protein in the YQHX group and the perindo-pril group was higher. The expression of GLUT4 protein in the DAPT group decreased. Compared with the YQHX group, the expression of GLUT4 protein in the DAPT+YQHX group was lower. There was no significant difference in the expression of ACC protein between the groups.CONCLUSION: YQHX promoted cross talk between the LKB1-dependent Notch1 and AMPK in myocardial tissue after myocardial infarction. Furthermore,it regulated the glucose and lipid metabolism of cardiomyocytes at different time points, thereby ameliorating the cardiac energy metabolism via different mechanisms and protecting the heart.