Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (...Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (body acupuncture group). After treatment of 28 days, changes of linguistic function and paralysis level of limbs before and after treatment were investigated. Results The total effective rate was 96.6% in the observation group and 90.7%, in the control group, with a significant difference between the two groups (P<0.05). Conclusion The electroacupuncture head point-through-point by penetrating two point therapy is one of effective methods for ischemic stroke.展开更多
Objective: To study the mechanism of electroacupuncture (EA) of scalp-points for regulating abnormal discharges of neurons in different regions around the cerebral hemorrhage focus by using neuro-electrophysiological ...Objective: To study the mechanism of electroacupuncture (EA) of scalp-points for regulating abnormal discharges of neurons in different regions around the cerebral hemorrhage focus by using neuro-electrophysiological methods. Methods: 80 Wistar rats (anesthetized with 20% urethane 1 g/kg, i.p.) were randomly divided into normal, saline, model and EA groups, with 20 cases in each group. Cerebral hemorrhage model was established by intracerebral injection of the rat’s own arterial blood sample (40 uL). In rats of saline group, the same volume of saline was given for intracerebral injection. Extracellular electrical activity of neurons of the caudate nucleus and parafascicular nucleus and Tail flicking latency (TFL) were used as the indexes. “Baihui”(百会 GV 20) and “Taiyang”(太阳 EX-HN 5) were punctured from GV 20 towards EX-HN 5 with filiform needles and stimulated electrically with stimulating parameters of strength of 1 V, frequency of 15 Hz and duration of 15 min. Results: Compared with normal group, TFL values of model group and EA group increased significantly (P<0.01); and compared with model group, those of EA group decreased significantly (P<0.01), suggesting that the pain threshold increased significantly in cerebral hemorrhage rats while after acupuncture stimulation, it lowered strikingly. Compared with normal and saline groups, the latency values of the pain excitement and inhibitory responses of the cellular discharges of the caudate and parafascicular nuclei in model and EA groups increased significantly (P<0.05~0.01), while after EA, it recovered apparently (P<0.01), showing an apparent regulative effect of EA on the abnormal changes of discharges of neurons around the cerebral hemorrhage focus. Conclusion: Scalp-acupuncture possesses an apparent regulatory effect on the abnormal electrical activity of neurons around the cerebral hemorrhage focus which may favor the early recovery of functional activity of neurons near the focus tissues.展开更多
Objective To introduce a new acupoint that has a good analgesic effect clinically. Methods According to the discovery, clinical exploration and clinical practice of Neimadian (内麻点) point, local anatomy, positioni...Objective To introduce a new acupoint that has a good analgesic effect clinically. Methods According to the discovery, clinical exploration and clinical practice of Neimadian (内麻点) point, local anatomy, positioning, manipulation, clinical application, precautions for manipulation and handling of adverse reactions of Nei madian point were summarized. Results After acupuncture at Neimadian point with continuous stimulation, it was shown that the level of serum β-endorphin increased significantly, while the level of angiotensin II was unchanged, indicating that acupuncture at Neimadian point has a good analgesic effect. Conclusion Acupuncture at Neimadian point can be used for clinical treatment of acute and chronic pain.展开更多
Objective To explore the effect of acupuncture combined with medicated thread moxibustion of Zhuang medicine on insomnia rats. Methods Sixty SPF Wistar rats were randomly divided into four groups, including a normal c...Objective To explore the effect of acupuncture combined with medicated thread moxibustion of Zhuang medicine on insomnia rats. Methods Sixty SPF Wistar rats were randomly divided into four groups, including a normal control group (control group), a sham operation group, a model group and a treatment group, with 15 rats in each group. In the model group and treatment group, insomnia model were established by injecting orexin into lateral ventricle of rats. In the sham operation group, artificial cerebrospinal fluid was injected into lateral ventricle of rats, and the rats in control group were not treated. On the basis of modeling, the rats in treatment group were treated by acupuncture combined with medicated thread moxibustion of Zhuang medicine which was conducted once a day, and the treatment lasted for 14 days. The expression of orexin mRNA and orexin content were detected, and the changes of associated receptors, including orexin 1 receptor (OX I R) and orexin 2 receptor (OX 2 R) were observed. Results The expression of orexin mRNA in model group (6.54 ± 1.21) significantly increased when compared with control group (0.66±0.12, P〈0.01), and orexin content in model group [(i 156.35±126.88) pg/mL] significantly increased when compared with control group [(427.12_± 32.54) pg/mL, P〈O.OI]. The expression of orexin mRNA in treatment group (0.87 ± 0.26) significantly reduced when compared with the model group (P〈0.01), and orexin content in the treatment group [(585.23 ± 89.21) pg/mL] significantly reduced when compared with the model group (P〈O.01). The percentage of OX I R positive cells in the model group (0.64±0.15) significantly increased when compared with the control group (0.21±0.03, P〈0.01), and the percentage of OX 2 R positive cells in the model group (0.76±0.18) significantly increased when compared with the control group (0.24±0.01, P〈O.01). The percentage of OX 1 R positive cells in the treatment group (0.36_±0.08) significantly reduced when compared with the model group (P〈0.01). The percentage of OX 2 R positive cells in treatment group (0.25_± 0.03) significantly reduced when compared with model group (P〈0.01). Conclusion It might be an effective link of acupuncture combined with medicated thread moxibustion of Zhuang medicine in treatment of insomnia that the treatment could inhibit the awakening promotion effect of orexin by affecting orexin, OX I R and OX 2 R.展开更多
Objective: To investigate the clinical efficacy of Zhang's acupoint pressure therapy plus electroacupuncture(EA) in treating post-traumatic knee osteoarthritis.Methods: A total of 98 eligible patients with post-t...Objective: To investigate the clinical efficacy of Zhang's acupoint pressure therapy plus electroacupuncture(EA) in treating post-traumatic knee osteoarthritis.Methods: A total of 98 eligible patients with post-traumatic knee osteoarthritis were divided into group A and B by the random number table, 49 cases in each group. Group A was intervened by Zhang's acupoint pressure therapy plus EA; group B was given medicinal fumigation. The clinical efficacies of the two groups were compared. Results: The markedly effective rate of group A was significantly higher than that of group B. Conclusion: Zhang's acupoint pressure therapy plus EA can produce a satisfactory clinical efficacy in treating post-traumatic knee osteoarthritis, and is worth promotion.展开更多
Objective To discuss the role of stuck needle therapy on cervical spondylotic radiculopathy. Method Fifty patients with cervical spondylot-ic radiculopathy were selected to accepted stuck needle therapy. Comprehensive...Objective To discuss the role of stuck needle therapy on cervical spondylotic radiculopathy. Method Fifty patients with cervical spondylot-ic radiculopathy were selected to accepted stuck needle therapy. Comprehensive curative effects were determined by Northwick Park Questionnaire (NPO) according to Criteria of Diagnosis and Therapeutic Effect of Diseases and Syndromes in Traditional Chinese Medicine. Results Eighteen cases with NPQ effect size ≥90% account for 36%; 27 cases with 90%〉NPO. effect size≥60% account for 54%; 3 cases with 60%〉NPQ effect size≥30% account for 6%; 2 cases with no improvement in symptom and body activity account for 4%. The total effective rate was up to 96%. Conclusion Stuck needle therapy on cervical spondylotic radiculopathy has significant curative effects.展开更多
Objective To observe the effect of muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting in improving nail fold microcirculation in the patients with shoulder-hand syndrome(...Objective To observe the effect of muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting in improving nail fold microcirculation in the patients with shoulder-hand syndrome(SHS)after stroke,and the effects on hemorrheology,calcitonin gene-related peptide(CGRP)and serum substance P(SP).Methods A total of 72 patients were randomized into an observation group and a control group by the random number table method,with 36 cases in each group.The control group was treated with physical rehabilitation training,and the observation group was treated with additional muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment.The treatment course lasted for 4 weeks.After treatment,the clinical efficacy of the two groups was compared.The changes in shoulder-hand syndrome scale(SHSS),simplified Fugl-Meyer assessment-upper extremity(FMA-UE),visual analog scale(VAS),activities of daily living(ADL),traditional Chinese medicine(TCM)syndrome score,nail fold microcirculation hemorheology indictors[whole blood viscosity(high-shear,low-shear),hematocrit,erythrocyte sedimentation rate(ESR)],CGRP and SP levels were observed.Results The total effective rate in the observation group was 86.1%,higher than 63.9%in the control group(P<0.05).The overall curative effect in the observation group was better than that in the control group(P<0.05).After treatment,the scores of pain sensation,edema,external turn and rotation of the arm in SHSS,and the total score were significantly decreased in both groups(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,the scores of VAS and TCM syndrome in both groups decreased significantly(all P<0.05),and the scores of FMA-UE and ADL increased significantly(all P<0.05).The scores of VAS and TCM syndrome in the observation group were lower than those in the control group(both P<0.05),and the scores of FMA-UE and ADL were higher than those in the control group(both P<0.05).After treatment,the whole blood viscosity(high-shear and low-shear)and hematocrit in both groups decreased obviously(all P<0.05),and ESR increased obviously(both P<0.05),and the whole blood viscosity(high-shear and low-shear)and hematocrit in the observation group were lower than those in the control group(all P<0.05),and ESR was higher than that in the control group(P<0.05).After treatment,the peritubular state,loop shape,blood flow and total score of nail fold microcirculation in both groups decreased significantly(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,SP in both groups decreased obviously(both P<0.05),CGRP increased obviously(both P<0.05),and SP in the observation group was lower than that in the control group(P<0.05),CGRP was higher than that in the control group(P<0.05).Conclusion Compared with conventional physical rehabilitation training,muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment can significantly reduce the clinical symptoms of SHS,promote the recovery of physical functions,improve the nail fold microcirculation and hemorrheology indictors,and regulate the serum cytokine levels such as CGRP and SP.展开更多
Objective:To observe the clinical effects of acupuncture at Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation for acute lumbar sprain. Methods:A total of 180 patients were divided into an observation...Objective:To observe the clinical effects of acupuncture at Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation for acute lumbar sprain. Methods:A total of 180 patients were divided into an observation group and a control group by drawing lots. The 98 cases in the observation group were treated by puncturing Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation. The 82 cases in the control group were only treated by the oblique Ban-pulling manipulation. After the two groups were treated continuously for three sessions, the therapeutic effects were observed. Results:In the observation group, 96 cases were cured and 2 cases were improved; the curative rate was 98.0% and the total effective rate was 100%. In the control group, 76 cases were cured, 4 cases were improved and 2 cases failed; the curative rate was 92.7% and the total effective rate was 97.6%. In comparison of the curative rate and total effective rate, the differences were not statistically significant (P〉0.05). But, the curative rate after the first treatment was higher in the observation group than that in the control group, with a significant difference between the two groups (P〈0.05). Conclusion:The therapeutic effects were similar by acupuncture at Yaotongdian (EX-UE 7) plus oblique Ban-pulling manipulation and by single oblique Ban-pulling manipulation for acute lumbar sprain. But, it took effect quickly by puncturing Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation.展开更多
基金This Study is one of the preeminent Researches in Chinese Medicine and Pharmacology supported by Jiangxi Health Care Administration. Code :2006A43~~
文摘Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (body acupuncture group). After treatment of 28 days, changes of linguistic function and paralysis level of limbs before and after treatment were investigated. Results The total effective rate was 96.6% in the observation group and 90.7%, in the control group, with a significant difference between the two groups (P<0.05). Conclusion The electroacupuncture head point-through-point by penetrating two point therapy is one of effective methods for ischemic stroke.
基金ThisworkwassubsidizedbyNationalNaturalScienceFoundationofChina (No .3 9670 90 2 ) .
文摘Objective: To study the mechanism of electroacupuncture (EA) of scalp-points for regulating abnormal discharges of neurons in different regions around the cerebral hemorrhage focus by using neuro-electrophysiological methods. Methods: 80 Wistar rats (anesthetized with 20% urethane 1 g/kg, i.p.) were randomly divided into normal, saline, model and EA groups, with 20 cases in each group. Cerebral hemorrhage model was established by intracerebral injection of the rat’s own arterial blood sample (40 uL). In rats of saline group, the same volume of saline was given for intracerebral injection. Extracellular electrical activity of neurons of the caudate nucleus and parafascicular nucleus and Tail flicking latency (TFL) were used as the indexes. “Baihui”(百会 GV 20) and “Taiyang”(太阳 EX-HN 5) were punctured from GV 20 towards EX-HN 5 with filiform needles and stimulated electrically with stimulating parameters of strength of 1 V, frequency of 15 Hz and duration of 15 min. Results: Compared with normal group, TFL values of model group and EA group increased significantly (P<0.01); and compared with model group, those of EA group decreased significantly (P<0.01), suggesting that the pain threshold increased significantly in cerebral hemorrhage rats while after acupuncture stimulation, it lowered strikingly. Compared with normal and saline groups, the latency values of the pain excitement and inhibitory responses of the cellular discharges of the caudate and parafascicular nuclei in model and EA groups increased significantly (P<0.05~0.01), while after EA, it recovered apparently (P<0.01), showing an apparent regulative effect of EA on the abnormal changes of discharges of neurons around the cerebral hemorrhage focus. Conclusion: Scalp-acupuncture possesses an apparent regulatory effect on the abnormal electrical activity of neurons around the cerebral hemorrhage focus which may favor the early recovery of functional activity of neurons near the focus tissues.
文摘Objective To introduce a new acupoint that has a good analgesic effect clinically. Methods According to the discovery, clinical exploration and clinical practice of Neimadian (内麻点) point, local anatomy, positioning, manipulation, clinical application, precautions for manipulation and handling of adverse reactions of Nei madian point were summarized. Results After acupuncture at Neimadian point with continuous stimulation, it was shown that the level of serum β-endorphin increased significantly, while the level of angiotensin II was unchanged, indicating that acupuncture at Neimadian point has a good analgesic effect. Conclusion Acupuncture at Neimadian point can be used for clinical treatment of acute and chronic pain.
基金Supported by National Natural Science Foundation of China:81360579
文摘Objective To explore the effect of acupuncture combined with medicated thread moxibustion of Zhuang medicine on insomnia rats. Methods Sixty SPF Wistar rats were randomly divided into four groups, including a normal control group (control group), a sham operation group, a model group and a treatment group, with 15 rats in each group. In the model group and treatment group, insomnia model were established by injecting orexin into lateral ventricle of rats. In the sham operation group, artificial cerebrospinal fluid was injected into lateral ventricle of rats, and the rats in control group were not treated. On the basis of modeling, the rats in treatment group were treated by acupuncture combined with medicated thread moxibustion of Zhuang medicine which was conducted once a day, and the treatment lasted for 14 days. The expression of orexin mRNA and orexin content were detected, and the changes of associated receptors, including orexin 1 receptor (OX I R) and orexin 2 receptor (OX 2 R) were observed. Results The expression of orexin mRNA in model group (6.54 ± 1.21) significantly increased when compared with control group (0.66±0.12, P〈0.01), and orexin content in model group [(i 156.35±126.88) pg/mL] significantly increased when compared with control group [(427.12_± 32.54) pg/mL, P〈O.OI]. The expression of orexin mRNA in treatment group (0.87 ± 0.26) significantly reduced when compared with the model group (P〈0.01), and orexin content in the treatment group [(585.23 ± 89.21) pg/mL] significantly reduced when compared with the model group (P〈O.01). The percentage of OX I R positive cells in the model group (0.64±0.15) significantly increased when compared with the control group (0.21±0.03, P〈0.01), and the percentage of OX 2 R positive cells in the model group (0.76±0.18) significantly increased when compared with the control group (0.24±0.01, P〈O.01). The percentage of OX 1 R positive cells in the treatment group (0.36_±0.08) significantly reduced when compared with the model group (P〈0.01). The percentage of OX 2 R positive cells in treatment group (0.25_± 0.03) significantly reduced when compared with model group (P〈0.01). Conclusion It might be an effective link of acupuncture combined with medicated thread moxibustion of Zhuang medicine in treatment of insomnia that the treatment could inhibit the awakening promotion effect of orexin by affecting orexin, OX I R and OX 2 R.
基金supported by Tuina Leading Department of the 12th Five-year Plan of National Health and Family Planning Commission of the People’s Republic of China/Tuina Leading Department of State Administration of Traditional Chinese Medicine/Zhang’s Bonesetting Academic School,No.LP0118052~~
文摘Objective: To investigate the clinical efficacy of Zhang's acupoint pressure therapy plus electroacupuncture(EA) in treating post-traumatic knee osteoarthritis.Methods: A total of 98 eligible patients with post-traumatic knee osteoarthritis were divided into group A and B by the random number table, 49 cases in each group. Group A was intervened by Zhang's acupoint pressure therapy plus EA; group B was given medicinal fumigation. The clinical efficacies of the two groups were compared. Results: The markedly effective rate of group A was significantly higher than that of group B. Conclusion: Zhang's acupoint pressure therapy plus EA can produce a satisfactory clinical efficacy in treating post-traumatic knee osteoarthritis, and is worth promotion.
文摘Objective To discuss the role of stuck needle therapy on cervical spondylotic radiculopathy. Method Fifty patients with cervical spondylot-ic radiculopathy were selected to accepted stuck needle therapy. Comprehensive curative effects were determined by Northwick Park Questionnaire (NPO) according to Criteria of Diagnosis and Therapeutic Effect of Diseases and Syndromes in Traditional Chinese Medicine. Results Eighteen cases with NPQ effect size ≥90% account for 36%; 27 cases with 90%〉NPO. effect size≥60% account for 54%; 3 cases with 60%〉NPQ effect size≥30% account for 6%; 2 cases with no improvement in symptom and body activity account for 4%. The total effective rate was up to 96%. Conclusion Stuck needle therapy on cervical spondylotic radiculopathy has significant curative effects.
文摘Objective To observe the effect of muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting in improving nail fold microcirculation in the patients with shoulder-hand syndrome(SHS)after stroke,and the effects on hemorrheology,calcitonin gene-related peptide(CGRP)and serum substance P(SP).Methods A total of 72 patients were randomized into an observation group and a control group by the random number table method,with 36 cases in each group.The control group was treated with physical rehabilitation training,and the observation group was treated with additional muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment.The treatment course lasted for 4 weeks.After treatment,the clinical efficacy of the two groups was compared.The changes in shoulder-hand syndrome scale(SHSS),simplified Fugl-Meyer assessment-upper extremity(FMA-UE),visual analog scale(VAS),activities of daily living(ADL),traditional Chinese medicine(TCM)syndrome score,nail fold microcirculation hemorheology indictors[whole blood viscosity(high-shear,low-shear),hematocrit,erythrocyte sedimentation rate(ESR)],CGRP and SP levels were observed.Results The total effective rate in the observation group was 86.1%,higher than 63.9%in the control group(P<0.05).The overall curative effect in the observation group was better than that in the control group(P<0.05).After treatment,the scores of pain sensation,edema,external turn and rotation of the arm in SHSS,and the total score were significantly decreased in both groups(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,the scores of VAS and TCM syndrome in both groups decreased significantly(all P<0.05),and the scores of FMA-UE and ADL increased significantly(all P<0.05).The scores of VAS and TCM syndrome in the observation group were lower than those in the control group(both P<0.05),and the scores of FMA-UE and ADL were higher than those in the control group(both P<0.05).After treatment,the whole blood viscosity(high-shear and low-shear)and hematocrit in both groups decreased obviously(all P<0.05),and ESR increased obviously(both P<0.05),and the whole blood viscosity(high-shear and low-shear)and hematocrit in the observation group were lower than those in the control group(all P<0.05),and ESR was higher than that in the control group(P<0.05).After treatment,the peritubular state,loop shape,blood flow and total score of nail fold microcirculation in both groups decreased significantly(all P<0.05),and each score in the observation group was lower than that in the control group(all P<0.05).After treatment,SP in both groups decreased obviously(both P<0.05),CGRP increased obviously(both P<0.05),and SP in the observation group was lower than that in the control group(P<0.05),CGRP was higher than that in the control group(P<0.05).Conclusion Compared with conventional physical rehabilitation training,muscle regions of meridians warm needling method plus pricking Jing-Well points for blood-letting treatment can significantly reduce the clinical symptoms of SHS,promote the recovery of physical functions,improve the nail fold microcirculation and hemorrheology indictors,and regulate the serum cytokine levels such as CGRP and SP.
文摘Objective:To observe the clinical effects of acupuncture at Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation for acute lumbar sprain. Methods:A total of 180 patients were divided into an observation group and a control group by drawing lots. The 98 cases in the observation group were treated by puncturing Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation. The 82 cases in the control group were only treated by the oblique Ban-pulling manipulation. After the two groups were treated continuously for three sessions, the therapeutic effects were observed. Results:In the observation group, 96 cases were cured and 2 cases were improved; the curative rate was 98.0% and the total effective rate was 100%. In the control group, 76 cases were cured, 4 cases were improved and 2 cases failed; the curative rate was 92.7% and the total effective rate was 97.6%. In comparison of the curative rate and total effective rate, the differences were not statistically significant (P〉0.05). But, the curative rate after the first treatment was higher in the observation group than that in the control group, with a significant difference between the two groups (P〈0.05). Conclusion:The therapeutic effects were similar by acupuncture at Yaotongdian (EX-UE 7) plus oblique Ban-pulling manipulation and by single oblique Ban-pulling manipulation for acute lumbar sprain. But, it took effect quickly by puncturing Yaotongdian (EX-UE 7) plus the oblique Ban-pulling manipulation.