目的 以药物利用评价(drug use evaluation,DUE)为基础,建立基于加权优劣解距离法(technique for order of preference by similarity to ideal solution,TOPSIS)的奥美拉唑静脉用药的合理性评价标准,为质子泵抑制剂专项点评提供参考。...目的 以药物利用评价(drug use evaluation,DUE)为基础,建立基于加权优劣解距离法(technique for order of preference by similarity to ideal solution,TOPSIS)的奥美拉唑静脉用药的合理性评价标准,为质子泵抑制剂专项点评提供参考。方法 根据国家指导原则、药品说明书、指南共识等,制定注射用奥美拉唑钠的合理性评价标准。随机调取2021年1—6月使用注射用奥美拉唑钠的病例作为对照组,7—12月的病例作为观察组。基于加权TOPSIS法计算各评价病例与正理想解的相对接近度(C_(i)),C_(i)≥80%判断为用药合理,60%≤C_(i)<80%判断为基本用药合理,C_(i)<60%判断为用药不合理。运用χ^(2)检验对观察组与对照组的合理率进行对比分析。结果 在对照组218例病例中,C_(i)≥80%的病例71例(32.57%),60%≤C_(i)<80%的128例(58.71%),C_(i)<60%的19例(8.72%)。观察组229例病例中,C_(i)≥80%的病例118例(51.53%),60%≤C_(i)<80%的104例(45.41%),C_(i)<60%的7例(3.06%)。观察组与对照组合理率相比,在适应证、给药剂量、给药疗程、药学监护及超医保限制用药方面,差异均具有统计学意义。结论 基于加权TOPSIS法所建立的注射用奥美拉唑钠的专项点评是合理且可行的,可降低点评人员的主观性评价,在加强医嘱点评力度、深度及实现标准化的专项点评方面可以提供参考。展开更多
The Contingent Valuation Method is used to evaluate individual preferences for a change concerning a public non-market resource or property. The objective is to build a nonparametric forecasting model of an individual...The Contingent Valuation Method is used to evaluate individual preferences for a change concerning a public non-market resource or property. The objective is to build a nonparametric forecasting model of an individual＇s Willingness To Pay according to geographical location. Within this framework, an estimator （of type Nadaraya-Watson） is proposed for the regression of the variable related to geolocation. The specific characteristics of the location variable lead us to a more general regression model than the traditional models. Results are established for convergence of our estimator.展开更多
文摘目的 以药物利用评价(drug use evaluation,DUE)为基础,建立基于加权优劣解距离法(technique for order of preference by similarity to ideal solution,TOPSIS)的奥美拉唑静脉用药的合理性评价标准,为质子泵抑制剂专项点评提供参考。方法 根据国家指导原则、药品说明书、指南共识等,制定注射用奥美拉唑钠的合理性评价标准。随机调取2021年1—6月使用注射用奥美拉唑钠的病例作为对照组,7—12月的病例作为观察组。基于加权TOPSIS法计算各评价病例与正理想解的相对接近度(C_(i)),C_(i)≥80%判断为用药合理,60%≤C_(i)<80%判断为基本用药合理,C_(i)<60%判断为用药不合理。运用χ^(2)检验对观察组与对照组的合理率进行对比分析。结果 在对照组218例病例中,C_(i)≥80%的病例71例(32.57%),60%≤C_(i)<80%的128例(58.71%),C_(i)<60%的19例(8.72%)。观察组229例病例中,C_(i)≥80%的病例118例(51.53%),60%≤C_(i)<80%的104例(45.41%),C_(i)<60%的7例(3.06%)。观察组与对照组合理率相比,在适应证、给药剂量、给药疗程、药学监护及超医保限制用药方面,差异均具有统计学意义。结论 基于加权TOPSIS法所建立的注射用奥美拉唑钠的专项点评是合理且可行的,可降低点评人员的主观性评价,在加强医嘱点评力度、深度及实现标准化的专项点评方面可以提供参考。
文摘The Contingent Valuation Method is used to evaluate individual preferences for a change concerning a public non-market resource or property. The objective is to build a nonparametric forecasting model of an individual＇s Willingness To Pay according to geographical location. Within this framework, an estimator （of type Nadaraya-Watson） is proposed for the regression of the variable related to geolocation. The specific characteristics of the location variable lead us to a more general regression model than the traditional models. Results are established for convergence of our estimator.
