AIM: To analyze the prevalence of gastroesophageal reflux disease (GERD) related symptoms in patients with diabetes mellitus (DM) and to find out the relationship between diabetic neuropathy and the prevalence of...AIM: To analyze the prevalence of gastroesophageal reflux disease (GERD) related symptoms in patients with diabetes mellitus (DM) and to find out the relationship between diabetic neuropathy and the prevalence of GERD symptoms. METHODS: In this prospective questionnaire study, 150 consecutive type 2 diabetic patients attending the endocrine clinic were enrolled. A junior physician helped the patients to understand the questions. Patients were asked about the presence of five most frequent symptoms of GERD that included heartburn (at least 1/wk), regurgitation, chest pain, hoarseness of voice and chronic cough. Patients with past medical history of angina, COPD, asthma, cough due to ACEI or preexisting GERD prior to onset of diabetes and apparent psychiatric disorders were excluded from the survey. We further divided the patients into two groups based on presence or absence of peripheral neuropathy. Out of 150 patients, 46 had neuropathy, whereas 104 patients did not have neuropathy. Data are expressed as mean ± SD, and number of patients in each category and percentage of total patients in that group. Normal distributions between groups were compared with Student t test and the prevalence rates between groups were compared with Chi-square tests for significance. RESULTS: The average duration of diabetes were 12 ± 9.2 years and the average HbAlc level of this group was 7.7% ± 2.0%. The mean weight and BMI were 198 ± 54 Ibs. and 32 ± 7.2 kg/m^2. Forty percent (61/150) patients reported having at least one of the symptoms of GERD and thirty percent (45/150) reported having heartburn at least once a week. The prevalence of GERD symptoms is higher in patients with neuropathy than patients without neuropathy (58.7% vs 32.7%, P 〈 0.01). The prevalence of heartburn, chest pain and chronic cough are also higher in patients with neuropathy than in patients without neuropathy (43.5% vs 24%; 10.9% vs 4.8% and 17.8% vs 6.7% respectively, P 〈 0.05). CONCLUSION: The prevalence of GERD symptoms in type 2 DM is higher than in the general population. Our data suggest that DM neuropathy may be an important associated factor for developing GERD symptoms.展开更多
Objective:To observe the clinical efficacy of triple needling plus moxibustion and Tanbo-plucking tender points in treating the third lumbar vertebra transverse process syndrome. Methods: Totally 108 patients with t...Objective:To observe the clinical efficacy of triple needling plus moxibustion and Tanbo-plucking tender points in treating the third lumbar vertebra transverse process syndrome. Methods: Totally 108 patients with the third lumbar vertebra transverse process syndrome were randomized into two groups, 56 cases in the observation group were intervened by triple needling method plus moxibustion and Tanbo-plucking tender points; 52 cases in the control group were by acupuncture plus moxibustion. The pain rating index(PRI), visual analogue scale (VAS), and present pain intensity (PPI) from the short-form McGill pain questionnaire (SF-MPQ) were observed before and after intervention for comparing the therapeutic efficacy. Results: The total effective rate was 96.4% in the observation group versus 76.9% in the control group, and the difference was statistically significant (P〈0.05). After intervention, the sensory-PRI, affective-PRI, totaI-PRI, VAS, and PPI scores were markedly changed in both groups (P〈0.05). The difference in comparing the change of clinical sign score was statistically significant between the two groups (P〈0.05). The follow-ups performed 4 weeks and 8 weeks after treatment showed that there were significant differences in comparing the relapse rate between the two groups (P〈0.05). Conclusion: Triple needling plus moxibustion and Tanbo-plucking tender points can produce a better efficacy in treating the third lumbar vertebra transverse process syndrome than acupuncture plus moxibustion alone, and the relapse rate is relatively low.展开更多
文摘AIM: To analyze the prevalence of gastroesophageal reflux disease (GERD) related symptoms in patients with diabetes mellitus (DM) and to find out the relationship between diabetic neuropathy and the prevalence of GERD symptoms. METHODS: In this prospective questionnaire study, 150 consecutive type 2 diabetic patients attending the endocrine clinic were enrolled. A junior physician helped the patients to understand the questions. Patients were asked about the presence of five most frequent symptoms of GERD that included heartburn (at least 1/wk), regurgitation, chest pain, hoarseness of voice and chronic cough. Patients with past medical history of angina, COPD, asthma, cough due to ACEI or preexisting GERD prior to onset of diabetes and apparent psychiatric disorders were excluded from the survey. We further divided the patients into two groups based on presence or absence of peripheral neuropathy. Out of 150 patients, 46 had neuropathy, whereas 104 patients did not have neuropathy. Data are expressed as mean ± SD, and number of patients in each category and percentage of total patients in that group. Normal distributions between groups were compared with Student t test and the prevalence rates between groups were compared with Chi-square tests for significance. RESULTS: The average duration of diabetes were 12 ± 9.2 years and the average HbAlc level of this group was 7.7% ± 2.0%. The mean weight and BMI were 198 ± 54 Ibs. and 32 ± 7.2 kg/m^2. Forty percent (61/150) patients reported having at least one of the symptoms of GERD and thirty percent (45/150) reported having heartburn at least once a week. The prevalence of GERD symptoms is higher in patients with neuropathy than patients without neuropathy (58.7% vs 32.7%, P 〈 0.01). The prevalence of heartburn, chest pain and chronic cough are also higher in patients with neuropathy than in patients without neuropathy (43.5% vs 24%; 10.9% vs 4.8% and 17.8% vs 6.7% respectively, P 〈 0.05). CONCLUSION: The prevalence of GERD symptoms in type 2 DM is higher than in the general population. Our data suggest that DM neuropathy may be an important associated factor for developing GERD symptoms.
基金supported by Shanghai Community Project of Traditional Chinese Medicine,No:SHJCZYYNLTS-SQZYYTS-21~~
文摘Objective:To observe the clinical efficacy of triple needling plus moxibustion and Tanbo-plucking tender points in treating the third lumbar vertebra transverse process syndrome. Methods: Totally 108 patients with the third lumbar vertebra transverse process syndrome were randomized into two groups, 56 cases in the observation group were intervened by triple needling method plus moxibustion and Tanbo-plucking tender points; 52 cases in the control group were by acupuncture plus moxibustion. The pain rating index(PRI), visual analogue scale (VAS), and present pain intensity (PPI) from the short-form McGill pain questionnaire (SF-MPQ) were observed before and after intervention for comparing the therapeutic efficacy. Results: The total effective rate was 96.4% in the observation group versus 76.9% in the control group, and the difference was statistically significant (P〈0.05). After intervention, the sensory-PRI, affective-PRI, totaI-PRI, VAS, and PPI scores were markedly changed in both groups (P〈0.05). The difference in comparing the change of clinical sign score was statistically significant between the two groups (P〈0.05). The follow-ups performed 4 weeks and 8 weeks after treatment showed that there were significant differences in comparing the relapse rate between the two groups (P〈0.05). Conclusion: Triple needling plus moxibustion and Tanbo-plucking tender points can produce a better efficacy in treating the third lumbar vertebra transverse process syndrome than acupuncture plus moxibustion alone, and the relapse rate is relatively low.