心悸寒证与热证心率变异性(HRV)与自主神经张力(交感和迷走)相关分析

[目的]观察心悸寒/热证心率变异性(heart rate variability,HRV)与自主神经张力(交感和迷走)相关性。[方法]使用前瞻性设计,平行对照方法,将141例住院及门诊患者按寒热证候归入实热、实寒、虚热、虚寒4组。观测HRV指标,时域指标SDNN、SDANN、RMSSD,频域指标TP、LF、HF、LF/HF。使用DMS动态分析软件,人工修正、去除伪差,自动分析24h连续心电信号(动态心电图)后,获得HRV各项指标。[结果]寒热辨证分组:热证82例(58.2%,82/141),其中实热32例,虚热50例;寒证59例(41.8%,59/141),均为虚寒证。SDNN、SDANN、RMSSD热证与寒证组间均无显著差异(P>0.05),虚寒组均大于虚热组(P<0.05)。TP、LF、HF热证与寒证组间均无显著差异(P>0.05),LF/HF热证组高于寒证(P<0.05);频域指标TP、HF、LF/HF虚热与虚寒均有显著差异(P<0.05),TP、HF虚寒大于虚热(P<0.05),LF/HF虚热组大于虚寒组(P<0.05),LF组间无显著差异(P>0.05),[结论]虚实与自主神经总张力相关,寒热与自主神经功能交感和迷走神经的张力平衡相关,热证与寒证自主神经总体能量无显著差异(P>0.05),热证组交感活动相对增强。

清脾泻热汤联合中药外敷、推拿按摩治疗小儿疱疹性口腔炎(心脾积热)随机平行对照研究

[目的]观察清脾泻热汤联合中药外敷、推拿按摩治疗小儿疱疹性口腔炎(心脾积热)疗效。[方法]使用随机平行对照方法,将59例住院及门诊患者按随机数字表法随机分为两组。对照组28例维生素C100～200mg,维生素B_6 100mg+5%葡萄糖200mL、0.9%氯化钠50mL,静滴,1次/d;人重组干扰素20ug/次,加入2mL注射液雾化吸入,2次/d。治疗组31例清脾泻热汤(金银花10g,连翘15g,竹叶、地黄~生、黄芩各10g,通草、升麻各6g,滑石^(包煎)10g,山栀子6g,薏米生10g,芦根15g,神曲~焦、麦芽~焦、山楂焦各10g,甘草6g),水煎200mL,2dl剂,少量多次口服;热重加柴胡10g,葛根15g;大便秘结加大黄~酒3g;口疮疮面色黄糜烂加黄连2～3g;外敷(桃仁、杏仁^(带皮尖)、山栀子各10g),捣末加入蛋清、白酒、面粉适量,调成糊状,夜晚临睡敷涌泉,次晨取下,连续5～7d;推拿(清脾胃300次,清天河水1000次,清小肠300次,发热加退六腑500次;烦躁惊悸加平肝200次、揉小天心200次;流涎重加揉小横纹300次、分推阴阳200次;腹胀纳呆加推四横纹300次,揉足三里100次)。连续治疗7d为1疗程。观测临床表现、退烧时间、口腔疱疹及溃疡改善时间、食欲改善时间、不良反应。治疗1疗程(7d),判定疗效。[结果]治疗组痊愈24例,好转6例,无效1例,总有效率96.77%;对照组痊愈9例,好转11例,无效8例,总有效率71.42%;治疗组疗效优于对照组(P<0.01)。退烧时间、口腔疱疹及溃疡改善时间、食欲改善时间治疗组均短于对照组(P<0.01)。[结论]清脾泻热汤联合中药外敷、推拿按摩治疗小儿疱疹性口腔炎(心脾积热),疗效满意,无严重不良反应,值得推广。

三黄泻心汤联合西药治疗脓毒症急性肾损伤(?三焦热盛?)随机平行对照研究

[目的]观察三黄泻心汤联合西药治疗脓毒症急性肾损伤(三焦热盛)疗效。[方法]使用随机平行对照方法,将78例住院患者按病志号抽签方法随机分为两组。对照组40例液体复苏,维持有效血容量;低潮气量通气,6m L/kg;氢化可的松,20~40mg/d,肌注;根据细菌培养结果给予抗生素,达到血液透析指征高通量血液透析,支持、对症治疗。治疗组38例三黄泻心汤(黄连6g,黄芩12g,大黄6g,甘草生12g,肉桂3g,乳香制、没药制各l0g,白及9g,大枣10g),150m L/次,2次/d,口服或鼻饲(昏迷或吞咽困难);西药治疗同对照组。连续治疗8d为1疗程。观测临床症状、急性生理学及慢性健康状况评分Ⅱ、中性粒细胞明胶酶相关脂质运载蛋白含量、尿肾损伤分子-1、血清半胱氨酸蛋白酶抑制剂C、IL-18、不良反应。治疗1疗程(8d),判定疗效。[结果]A-PACHEⅡ评分、NGAL、Kim-1、Cys C、IL-18两组均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.05,P<0.01)。[结论]三黄泻心汤联合西药治疗脓毒症急性肾损伤(三焦热盛),疗效满意,无严重不良反应,值得推广。

让内容有一颗“互动的心”——以《柳州日报》新闻报道与新媒体相融相合为例

在当前内容同质化的媒体生态环境下,只有打动人心的内容,才是好内容;好内容关键在于与用户的互动和参与,互动聚集人气,高人气引发高关注。所以说,好内容的"王气"从"人心"来,有"心",才是真正的"内容为王"。

HEAT TRANSFER CHARACTERISTICS OF NEW COOLING TECHNIQUE BASED ON THERMAL DRIVING

A new cooling technique based on thermal driving in high centrifugal field （TDHCF） is developed for gas turbine rotational components, such as turbine blades. The key point of TDHCF is to enhance heat transfer by the fluid thermal driving in closed loop small channels placed in the high centrifugal field. Heat transfer characteristics of the new cooling technique are analyzed. In experiments, two different fluids （liquid water and Freon R12） are used as thermal driving media （fluid inside the loop channel）. And the channel width d is 1 mm and the height h is 30 mm. The temperature is measured by thermocouples and an average heat transfer coefficient KH is defined to indicate heat transfer capacity of TDHCF. Experimental results show that KH is enhanced when heat flux and the rotating speed increase. And thermal properties of thermal driving media are also influenced by KH. Larger KH can be achieved by using Freon R12 as thermal driving medium compared with using liquid water. It can increase to 2 300 W/（m^2 · K） and it is much higher than that of the normal air cooling method （usually at the level of 600-1200 W/（m^2·K））. All fundamental studies of TDHCF show that there actually exists thermal driving in the closed loop small channel in the centrifugal field to improve heat transfer characteristics.

注重德育渗透 落实全员德育

以理解、尊重为基础，以“爱心”为出发点，以使充分发挥情感教育作用；教会赏识的方法，增强“自信心”教育；尽“心”关注后进生的敏感心理，让后进生真正得到转化；热“心”开展活动，注重学生体验，从而实现德育目标、优化德育渗透。

Prediction of compressive strength of cement mortars with fly ash and activated coal gangue

The pozzolanic activity of coal gangue, which is calcining at 500 to 1 000 ℃, differs distinctly. The simplex-centroid design with upper and lower bounds of component proportion is adopted to study the compressive strength of mortars made with ternary blends of cement, activated coal gangue and fly ash. Based on the results of a minimum of seven design points, three special cubic polynomial models are used to establish the strength predicating equations at different ages for mortars. Five experimental checkpoints were also designed to verify the precision of the equations. The most frequent errors of the predicted values are within 3%. A simple and practical way is provided for determining the optimal proportion of two admixtures when they are used in concrete.

Are heat stroke and physical exhaustion underestimated causes of acute hepatic failure?

While cardiopulmonary symptoms are common in patients undergoing dassical or, due to physical exercise, exertional heat stroke, the failure of other organs is a rarely described phenomenon. Here we present two cases of acute hepatic failure, one due to classic heat shock, while the other occurred while the patient was doing a marathon-type running. Both cases presented with very high transaminases and significantly elevated international normalized ratio （INR）. No other causes for liver failure could be identified but physical exhaustion and hyperthermia.

H pylori infection and systemic antibodies to CagA and heat shock protein 60 in patients with coronary heart disease

AIM: To determine the overall prevalence of H pylori and CagA positive H pylori infection and the prevalence of other bacterial and viral causes of chronic infection in patients with coronary heart disease (CHD), and the potential role of anti-heat-shock protein 60 (Hsp60) anti- body response to these proteins in increasing the risk of CHD development. METHODS: Eighty patients with CHD and 160 controls were employed. We also compared the levels of anti- heat-shock protein 60 (Hsp60) antibodies in the two groups. The H pylori infection and the CagA status were determined serologically, using commercially available enzyme-linked immunosorbent assays (ELISA), and a Western blotting method developed in our laboratory. Systemic antibodies to Hsp60 were determined by a sandwich ELISA, using a polyclonal antibody to Hsp60 to sensitise polystyrene plates and a commercially available human Hsp60 as an antigen. RESULTS: The overall prevalence of H pylori infec- tion was 78.7% (n = 63) in patients and 76.2% (n = 122) in controls (P = 0.07). Patients infected by CagA- positive (CagA+) H pylori strains were 71.4% (n = 45) vs 52.4% of infected controls (P = 0.030, OR = 2.27). Sys-temic levels of IgG to Hsp60 were increased in H pylori- negative patients compared with uninfected controls (P < 0.001) and CagA-positive infected patients compared with CagA-positive infected controls (P = 0.007). CONCLUSION: CagA positive H pylori infection may concur to the development of CHD; high levels of anti- Hsp60 antibodies may constitute a marker and/or a con- comitant pathogenic factor of the disease.

Building dynamic thermal simulation of low-order multi-dimensional heat transfer

Multi-dimensional heat transfers modeling is crucial for building simulations of insulated buildings,which are widely used and have multi-dimensional heat transfers characteristics.For this work,state-model-reduction techniques were used to develop a reduced low-order model of multi-dimensional heat transfers.With hot box experiment of hollow block wall,heat flow relative errors between experiment and low-order model predication were less than 8% and the largest errors were less than 3%.Also,frequency responses of five typical walls,each with different thermal masses or insulation modes,the low-order model and the complete model showed that the low-order model results agree very well in the lower excitation frequency band with deviations appearing only at high frequency.Furthermore,low-order model was used on intersection thermal bridge of a floor slab and exterior wall.Results show that errors between the two models are very small.This low-order model could be coupled with most existing simulation software for different thermal mass envelope analyses to make up for differences between the multi-dimensional and one-dimensional models,simultaneously simplifying simulation calculations.

Surface density of synthetically tuned spinel oxides of Co^(3+) and Ni^(3+) with enhanced catalytic activity for methane oxidation

Spinel oxides containing Co and Ni are a promising substitute as a noble metal catalyst for methane combustion.Achieving a complete oxidation of methane under 400°C remains challenging,andhydrothermal 60 h NiClittle impact on activity,especially at high space velocities due to the long hydrothermal time with less absorbed oxygen species and crystal defects.Overall,these results help clarify methane activa-tion mechanisms and aid the development of more efficient low-cost catalysts.

Response Surface Optimization for Process Parameters of LiFePO_4/C Preparation by Carbothermal Reduction Technology

A statistically based optimization strategy is used to optimize the carbothermal reduction technology for the synthesis of LiFePO4/C using LiOH,FePO4 and sucrose as raw materials.The experimental data for fitting the response are collected by the central composite rotatable design(CCD).A second order model for the discharge ca-pacity of LiFePO4/C is expressed as a function of sintering temperature,sintering time and carbon content.The ef-fects of individual variables and their interactions are studied by a statistical analysis(ANOVA).The results show that the linear effects and the quadratic effects of sintering temperature,carbon content and the interactions among these variables are statistically significant,while those effects of sintering time are insignificant.Response surface plots for spatial representation of the model illustrate that the discharge capacity depends on sintering temperature and carbon content more than sintering time.The model obtained gives the optimized reaction parameters of sinter-ing temperature at 652.0 ℃,carbon content of 34.33 g?mol-1 and 8.48 h sintering time,corresponding to a dis-charge capacity of 150.8 mA·h·g-1.The confirmatory test with these optimum parameters gives the discharge ca-pacity of 147.2 and 105.1 mA·h·g-1 at 0.5 and 5 C,respectively.

Effects of Ultra-drying Treatment on Large Amounts of Four Kinds of Crop Seeds

This study was to understand the physiological changes of four kinds of crop seeds including baby corn, cowpea, radish and rape- seed, under the treatment of ultra-drying. Large amounts of seeds as experimental materials （ 10 kg for each material） were respectively dried to the suitable water content consistent with the ultra-dried seed criterion via heating at 50 ~C; then the physiological indices of these ultra-dried seeds such as water content, seed germination, dehydrogenase activity and SOD activity were measured. The results showed that except cowpea seeds, whose ultra-drying treatment should be controlled between two and four days, other three kinds of seeds were tolerant to high tem- perature and low water content. The ultra-dried seeds assumed similar or even higher activities than CKs, but showed no damage symptom. Our result proves that ultra-drying treatment via heating at 50 ℃ is safe and efficient to experimental seeds.

A Preliminary Study on the Relation Between the Thermal and Geometric Surface Centroids of the Western Pacific Warm Pool

Numerous published results have showr the importance of the Wcstern Pacific Warm Pool （WPWP）surface centroid movement in ENSO-（EI Nino/Southcrn Oscillation）rclated studies .Howcver,some rccent research conclusions make it necessary to clarify the differenccs of the currently exicing two types of WPWP surface centroid：the geometric centroid and the thermal （heat）centrold.This study analyzes the physical backgrounds of the two typcs of centroid and points out their differenccs.which suggest that different types of ccntroid may scrve different study purposes.This study also shows that the ‘geometric center’of WPWP.actually a close approximation to the mass ccntroid,is more related to the Nino-3 region sca surfacc temperaturc（SST）ancmaly and can also be regarded as an important indicator of ENSO events.

Metallurgical behavior and variation of vibro-acoustic signal during preheating assisted friction stir welding between AA6061-T6 and AA7075-T651 alloys

The present work investigated the effects of pin profiles(cylindrical and square),pin eccentricity(0.5 mm and 1 mm)in cylindrical tool and preheating(secondary heating)on metallurgical behavior,variation of vibro-acoustic signal pattern and joint strength during friction stir welding(FSW)between AA6061-T6 and AA7075-T651 alloys.The eccentric tool pins were observed to provide good flowability and intermixing between dissimilar metals,increased the size of stir zone,and the grains in stir zone were sufficiently finer with eccentric tool pin than concentric pin.The magnitude of vibro-acoustic signal increased when shoulder plunging started and drop in signal was noted when the tool shoulder reached its desired depth.The signal magnitude was noted to be higher in welding stage compared to tool plunging stage as the tool took in fresh material during tool movement along the weld path.Preheating the workpiece prior to pin plunging and during welding notably influenced the flow behavior and mixing pattern,and the grains in stir zone were slightly coarser than those in specimen without preheating.Significant reduction in the magnitude of the signal was also observed after preheating.Tensile and flexural strength of joints were also improved slightly when additional heating was employed.

Thermoelastic stresses in a uniformly heated functionally graded isotropic hollow cylinder

The axisymmetric thermoelastic problem of a uniformly heated, functionally graded isotropic hollow cylinder is considered. An analytical form of solution is proposed. For the case when the Young's modulus and thermal expansion coefficient have a power\|law dependence on the radial coordinate, explicit exact solution is obtained. For the degenerated case, i.e. when the cylinder is homogeneous and isotropic, no stresses will occur provided it is subjected to a uniform temperature. Numerical results are finally given and some important inclusions are obtained.

Analysis of Heat Transfer Performance of Oscillating Heat Pipes Based on a Central Composite Design

Oscillating heat pipes (OHPs) are very promising cooling devices. Their heat transfer performance is af- fected by many factors, and the form of the relationship between the performance and the factors is complex and non-linear. In this paper, the effects of charging ratio, inclination angle, and heat input and their interaction effects on heat transfer performance of a looped copper-water OHP are analyzed. First, suppose that the relationship between the response and the variables approximates a second-order model. And use the central composite design to arrange the ex- periment. Then, the method of least squares is used to estimate the parameters in the second-order model. Finally, multi- variate variance analysis is used to analyze the model. The results show that the assumption is right, that is to say, the re- lationship is well modeled by a second-order function. Among the three main effect variables, the effect of inclination angle is the most significant, but their interaction effects are not significant. In the range of the considered factors, both the optimum charging ratio and the optimum inclination angle increase as the heating water flow rate increases.

Rainfall Variability Patterns in West Africa： Case of Cote d＇lvoire and Ghana

This study is focused first on the rainfall variability in C6te d＇Ivoire and in Ghana; second, on the determination of the climatic zones of these areas. Monthly rainfall heights recorded in 43 weather stations from 1964 to 2000 is carried out. This study suggests a sudivision in three climatic zones which are： the littoral zone that borders the tropical Atlantic, the center zone that is located in the central region of both countries, and the northern zone whose seasonal cycle is close to that of the Sahel of West Africa. The study of the interannual variability of the rainfall shows some patterns which are differently influenced by sea surface temperature. Such work could be useful for agricultural activities and to better quantify the role of the vegetation dynamics.

Theoretical solution of a spherically isotropic hollow sphere for dynamic thermoelastic problems

The separation of variables method was successfully used to resolve the spherically symmetric dynamic thermoelastic problem for a spherically isotropic elastic hollow sphere. Use of the integral transform can be avoided by means of this method, which is also appropriate for an arbitrary thickness hollow sphere subjected to arbitrary thermal and mechanical loads. Numerical results are presented to show the dynamic stress responses in the uniformly heated hollow spheres.

Constitutively Expressed αB—Crystallin in Heat Schock Transcription Factor 1 Knockout Mice Myocardium

Objective-To investigate the effects of heat shock transcription factor 1) gene on the constitutivety expressed αB-CrystaUin (aBC) in mice myocardium. Methods-The expression levels of constitutive aBC in HSF1 knockout (hsf1 - /- ) and HSFl wild type (As/1 + /+) mice myocardium were evaluated by western blot and immunohistochemistry. Results : The αBC levels in hsfl -/- and hsfl +/+ were 68. 42±4. 16, 100. 00±7. 58, respectively (P<0. 05, cytoso-lic fraction) , and 20. 53±1. 01, 37. 55±1. 91, respectively (P<0. 05, pellet fraction). The aBC signals decreased significantly in hsfl -/- myocardium when compared with those in hsfl +/+ myocardium stained with fluorescence immunohistochemistry. Conclusion-HSF1 is an important, but not the only factor, which mediates the constitutively expressed aBC.