The adsorption kinetics and mechanism of a novel chelate resin, macroporous phosphonic acid resin (PAR) for In(III) were investigated. The statically saturated adsorption capacity is 216mg穏-1resin at 298K in HAc-NaAc...The adsorption kinetics and mechanism of a novel chelate resin, macroporous phosphonic acid resin (PAR) for In(III) were investigated. The statically saturated adsorption capacity is 216mg穏-1resin at 298K in HAc-NaAc medium. The apparent adsorption rate constant is k298=4.84?0-5 s-1. The adsorption behavior of PAR for In(III) obeys the Freundlich isotherm. The thermodynamic adsorption parameters, enthalpy change △H, free energy change △G and entropy change △S of PAR for In(III) are 11.5kJ/mol, -12.6kJ/mol and 80.8J/mol稫, respectively. The apparent activation energy is Ea=3.5kJ/mol. The molar coordination ratio of the functional group of PAR to In(III) is about 3∶1.展开更多
Under the direction of the principle of interaction between plastic volumetric and shear strains, the general expression of constitutive relation for geotechnical materials has been derived within the framework of irr...Under the direction of the principle of interaction between plastic volumetric and shear strains, the general expression of constitutive relation for geotechnical materials has been derived within the framework of irreversible thermo- dynamics. The constitutive modeling, in fact, is an inverse problem that belongs to the medium inverse problems of model identification, which is expressed as a reversion of coefficient of differential equation. Thus the constitutive modeling of geotechnical materials will become the reversion of coefficient functions of the general expression of constitutive relation, which is carried out in the stress field （p,q） by means Of numerical techniques, so that is called numerical modeling. Applying the numerical modeling, a number of plasticity-based models for clay and sand have been obtained, which are able to characterize the fundamental features of deformation for geotechnieal materials. In addition, the approach of numerical modeling also can be applied to the situation of unsaturated soils by means of the Bishop＇s effective stress formula and Khalili＇s expression of effective stress parameter.展开更多
Methylation in the bases of DNA is known to induce B-Z conformation change. In this work, molecular mechanics and normal mode analysis are used to probe how certain methylation affects the internal interactions and th...Methylation in the bases of DNA is known to induce B-Z conformation change. In this work, molecular mechanics and normal mode analysis are used to probe how certain methylation affects the internal interactions and thermodynamic motions in the DNA double helixes in both B and Z conformations, and its implication to B-Z conformation change. By molecular modeling with Insight II, two cases involving cytosine C5 and guanine C8 methylation on both B and Z-form DNA duplex d(CGCGCG)2 are studied in comparison with the corresponding unmethylated duplexes. The internal interaction energies computed based on a molecular mechanics force field and the entropies due to internal motions computed according to a normal mode analysis are in fare agreement with respective observed thermodynamic quantities. The analysis on the computed individual energy terms suggests that the observed B-Z conformation change induced by methylation is primarily driven by enthalpic factors. A combination of changes in Van der Waals interaction, electrostatic interaction and hydrogen bonding likely contributes to the change of enthalpy that favors Z-conformation in the methylated states.展开更多
The quality of Radix saposhnikoviae（RS） had deteriorated due to the adoption of cultivated plants rather than wild plants. High temperature treatment increases the content of several chromones, however using one or ...The quality of Radix saposhnikoviae（RS） had deteriorated due to the adoption of cultivated plants rather than wild plants. High temperature treatment increases the content of several chromones, however using one or more individual constituents would be difficult to determine the medical quality of RS. In this paper, we used pharmacokinetic and pharmacologic approaches to evaluate the quality of RS. The active constituents were analysed using pharmacokinetic parameters of the chromone derivatives, and the antipyretic, analgesic, and anti-inflammatory effects were evaluated by pyretic animal model, hot plate test, and ear edema model, respectively. Only cimifugin was found in plasma after RS and heat-stress-RS were administered to rats, with a 50.6% increase in AUC0–24 h of cimifugin in the latter. Likewise, more potent anti-pyretic, analgesic, and anti-inflammatory activities were also found in the latter. Exposure of S. divaricata fresh roots to high temperatures enhanced the antipyretic, analgesic, and anti-inflammatory effects of RS by promoting the absorption of cimifugin.展开更多
We introduce a pre-hydrodynamic correction to the commonly used Glauber model to bring the random scattering information to the initial condition of the hydrodynamic description for the heavy ion collisions.The result...We introduce a pre-hydrodynamic correction to the commonly used Glauber model to bring the random scattering information to the initial condition of the hydrodynamic description for the heavy ion collisions.The results of this correction obviously shrink the value of the elliptic flow in the medium momentum region and move the corresponding momentum of the maximum v 2 forwards to smaller p T value.These fit the experimental data quite well.This correction implies that the quark-gluon plasma(QGP) has reached the thermal equilibrium when the hydrodynamic expansion starts.Such a conclusion of quick-equilibrium confirms the conclusion that QGP is a strongly interacting system.展开更多
基金Zhoushan Science & Technology Bureau (No. 04114)
文摘The adsorption kinetics and mechanism of a novel chelate resin, macroporous phosphonic acid resin (PAR) for In(III) were investigated. The statically saturated adsorption capacity is 216mg穏-1resin at 298K in HAc-NaAc medium. The apparent adsorption rate constant is k298=4.84?0-5 s-1. The adsorption behavior of PAR for In(III) obeys the Freundlich isotherm. The thermodynamic adsorption parameters, enthalpy change △H, free energy change △G and entropy change △S of PAR for In(III) are 11.5kJ/mol, -12.6kJ/mol and 80.8J/mol稫, respectively. The apparent activation energy is Ea=3.5kJ/mol. The molar coordination ratio of the functional group of PAR to In(III) is about 3∶1.
文摘Under the direction of the principle of interaction between plastic volumetric and shear strains, the general expression of constitutive relation for geotechnical materials has been derived within the framework of irreversible thermo- dynamics. The constitutive modeling, in fact, is an inverse problem that belongs to the medium inverse problems of model identification, which is expressed as a reversion of coefficient of differential equation. Thus the constitutive modeling of geotechnical materials will become the reversion of coefficient functions of the general expression of constitutive relation, which is carried out in the stress field （p,q） by means Of numerical techniques, so that is called numerical modeling. Applying the numerical modeling, a number of plasticity-based models for clay and sand have been obtained, which are able to characterize the fundamental features of deformation for geotechnieal materials. In addition, the approach of numerical modeling also can be applied to the situation of unsaturated soils by means of the Bishop＇s effective stress formula and Khalili＇s expression of effective stress parameter.
基金the International Joint Research Project of Chongqing University and National University of Singapore (ARF-151-000-014-112) and the Basic and Applied Research Foundation of Chongqing University.
文摘Methylation in the bases of DNA is known to induce B-Z conformation change. In this work, molecular mechanics and normal mode analysis are used to probe how certain methylation affects the internal interactions and thermodynamic motions in the DNA double helixes in both B and Z conformations, and its implication to B-Z conformation change. By molecular modeling with Insight II, two cases involving cytosine C5 and guanine C8 methylation on both B and Z-form DNA duplex d(CGCGCG)2 are studied in comparison with the corresponding unmethylated duplexes. The internal interaction energies computed based on a molecular mechanics force field and the entropies due to internal motions computed according to a normal mode analysis are in fare agreement with respective observed thermodynamic quantities. The analysis on the computed individual energy terms suggests that the observed B-Z conformation change induced by methylation is primarily driven by enthalpic factors. A combination of changes in Van der Waals interaction, electrostatic interaction and hydrogen bonding likely contributes to the change of enthalpy that favors Z-conformation in the methylated states.
基金National Natural Science Foundation of China(Gr ant No.81541079)Natural Science Foundation of Heilongjiang province(Grant No.H2017065)the Doctoral Scientific Research Fou ndation of Liaoning Province(Grant No.20170520132)
文摘The quality of Radix saposhnikoviae（RS） had deteriorated due to the adoption of cultivated plants rather than wild plants. High temperature treatment increases the content of several chromones, however using one or more individual constituents would be difficult to determine the medical quality of RS. In this paper, we used pharmacokinetic and pharmacologic approaches to evaluate the quality of RS. The active constituents were analysed using pharmacokinetic parameters of the chromone derivatives, and the antipyretic, analgesic, and anti-inflammatory effects were evaluated by pyretic animal model, hot plate test, and ear edema model, respectively. Only cimifugin was found in plasma after RS and heat-stress-RS were administered to rats, with a 50.6% increase in AUC0–24 h of cimifugin in the latter. Likewise, more potent anti-pyretic, analgesic, and anti-inflammatory activities were also found in the latter. Exposure of S. divaricata fresh roots to high temperatures enhanced the antipyretic, analgesic, and anti-inflammatory effects of RS by promoting the absorption of cimifugin.
基金supported by the National Natural Science Foundation of China (Grant Nos. 10775069,10935001 and 11075075)the Research Fund for the Doctoral Program of Higher Education (Grant No.200802840009)the Priority Academic Program Development of Jiangsu Higher Education Institution
文摘We introduce a pre-hydrodynamic correction to the commonly used Glauber model to bring the random scattering information to the initial condition of the hydrodynamic description for the heavy ion collisions.The results of this correction obviously shrink the value of the elliptic flow in the medium momentum region and move the corresponding momentum of the maximum v 2 forwards to smaller p T value.These fit the experimental data quite well.This correction implies that the quark-gluon plasma(QGP) has reached the thermal equilibrium when the hydrodynamic expansion starts.Such a conclusion of quick-equilibrium confirms the conclusion that QGP is a strongly interacting system.
