In our previous study, we observed that there was a close relation between the therapeutic effect and the warm receptors (WRs) or polymodal receptors (PRs). In accordance with the most sensitivity of WRs and the therm...In our previous study, we observed that there was a close relation between the therapeutic effect and the warm receptors (WRs) or polymodal receptors (PRs). In accordance with the most sensitivity of WRs and the thermal threshold value, we used computer controlled projector light at a constant temperature 40°C and 47°C to irradiate (moxibustion) Dazhui (GV 14) and Baihui (GV 20) (it is located between the spines of the 7th lumbar vertebra and the its sacral vertebra in the rabbit) and observed its antipyretic action on fever induced by intravenous injection of endotoxin in the rabbit. Results showed that this kind of moxibustion at 40°C had no significant effect while that at 47°C had a very striking antipyretic effect, indicating that the antipyretic effect of moxibustion is mediated primarily by PRs. This fact also provides an important experimental evidence for moxibustion treatment of heat syndrome of traditional Chinese medicine (TCM).展开更多
文摘In our previous study, we observed that there was a close relation between the therapeutic effect and the warm receptors (WRs) or polymodal receptors (PRs). In accordance with the most sensitivity of WRs and the thermal threshold value, we used computer controlled projector light at a constant temperature 40°C and 47°C to irradiate (moxibustion) Dazhui (GV 14) and Baihui (GV 20) (it is located between the spines of the 7th lumbar vertebra and the its sacral vertebra in the rabbit) and observed its antipyretic action on fever induced by intravenous injection of endotoxin in the rabbit. Results showed that this kind of moxibustion at 40°C had no significant effect while that at 47°C had a very striking antipyretic effect, indicating that the antipyretic effect of moxibustion is mediated primarily by PRs. This fact also provides an important experimental evidence for moxibustion treatment of heat syndrome of traditional Chinese medicine (TCM).