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大江币版模和纸张研究
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作者 徐海涛 《安徽文博》 2020年第1期64-68,共5页
大江银行是皖江抗日根据地唯一的金融机构,在1942年至1945年发行了大江币,大江币对皖江抗日根据地经济繁荣起了重大的作用。版模和纸张是大江币制币过程中重要的两个环节,对大江币以后的流通和使用有着直接的影响。
关键词 皖江根据地 大江币 版模 纸张
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A Novel Algorithm to Extract Weighted Critical Area
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作者 王俊平 郝跃 +2 位作者 张会宁 张晓菊 任春丽 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2006年第1期24-29,共6页
inductive fault analysis is a technique for enumerating likely bridges that is limited by the weighted critical area computation. Based on the rectangle model of a real defect and mathematical morphology, an efficient... inductive fault analysis is a technique for enumerating likely bridges that is limited by the weighted critical area computation. Based on the rectangle model of a real defect and mathematical morphology, an efficient algorithm is presented to compute the weighted critical area of a layout. The algorithm avoids the need to determine which rectangles belong to a net and the merging of the critical area corresponding to a net pair. Experimental resuits showing the algorithm's performance are presented. 展开更多
关键词 bridge fault defect rectangle model layout analysis mathematical morphology
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Optimal Stack Generation for CMOS Analog Modules with Parasitic and Mismatch Constraints
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作者 曾璇 李明原 +2 位作者 赵文庆 唐璞山 周电 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2001年第1期1-10,共10页
The performances of analog circuits depend greatly on the layout parasitics and mismatches.Novel techniques are proposed for modeling the distributed parasitic capacitance,parasitic parameter mismatch due to process g... The performances of analog circuits depend greatly on the layout parasitics and mismatches.Novel techniques are proposed for modeling the distributed parasitic capacitance,parasitic parameter mismatch due to process gradient and the inner stack routing mismatch.Based on the proposed models,an optimal stack generation technique is developed to control the parasitics and mismatches,optimize the stack shape and ensure the generation of an Eulerian graph for a given CMOS analog module.An OPA circuit example is given to demonstrate that the circuit performances such as unit gain bandwidth and phase margin are enhanced by the proposed layout optimization method. 展开更多
关键词 analog constraints analog circuits layout stack generation
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A Systematic Study of the Forbidden Pitch in the CD Through-Pitch Curve for Beyond 130nm
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作者 赵宇航 朱骏 曹永峰 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第5期889-892,共4页
The forbidden pitch "dip" in the critical dimension (CD) through the pitch curve is a well-known optical proximity effect. The CD and CD process window near the "dip",usually found near a pitch range of 1.1 to 1... The forbidden pitch "dip" in the critical dimension (CD) through the pitch curve is a well-known optical proximity effect. The CD and CD process window near the "dip",usually found near a pitch range of 1.1 to 1.4 wavelength/ NA (numerical aperture),is smaller when compared with other pitches. This is caused by inadequate imaging contrast for an unequal line and space grating. Although this effect is relatively well-known, its relationship with typical process condition parameters,such as the effective image blur caused by the photo-acid diffusion during the post exposure bake or the aberration in the imaging lens, has not been systematically studied. In this paper, we will examine the correlation between the image blur and the effect on the CD, including the decrease in the CD value (the depth of the "dip") and the CD process window. We find that both the decrease in the CD value and the focus latitude near the forbidden pitch correlate very well with the effective Gaussian image blur. Longer effective diffusion length correlates well with a smaller process window and a deeper CD "dip". We conclude that the dip depth is very sensitive to the change in image contrast. 展开更多
关键词 forbidden pitch effective resist diffusion length OPC OAI deep-UV
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Modeling of Arctic Sea Ice Variability During 1948–2009: Validation of Two Versions of the Los Alamos Sea Ice Model(CICE) 被引量:7
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作者 WU Shu-Qiang ZENG Qing-Cun BI Xun-Qiang 《Atmospheric and Oceanic Science Letters》 CSCD 2015年第4期215-219,共5页
The Los Alamos sea ice model(CICE) is used to simulate the Arctic sea ice variability from 1948 to 2009. Two versions of CICE are validated through comparison with Hadley Centre Global Sea Ice and Sea Surface Temperat... The Los Alamos sea ice model(CICE) is used to simulate the Arctic sea ice variability from 1948 to 2009. Two versions of CICE are validated through comparison with Hadley Centre Global Sea Ice and Sea Surface Temperature(Had ISST) observations. Version 5.0 of CICE with elastic-viscous-plastic(EVP) dynamics simulates a September Arctic sea ice concentration(SASIC) trend of –0.619 × 1012 m2 per decade from 1969 to 2009, which is very close to the observed trend(-0.585 × 1012 m2 per decade). Version 4.0 of CICE with EVP dynamics underestimates the SASIC trend(-0.470 × 1012 m2 per decade). Version 5.0 has a higher correlation(0.742) with observation than version 4.0(0.653). Both versions of CICE simulate the seasonal cycle of the Arctic sea ice, but version 5.0 outperforms version 4.0 in both phase and amplitude. The timing of the minimum and maximum sea ice coverage occurs a little earlier(phase advancing) in both versions. Simulations also show that the September Arctic sea ice volume(SASIV) has a faster decreasing trend than SASIC. 展开更多
关键词 Arctic sea ice trend analysis model validation Los Alamos sea ice model(CICE)
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Dynamic batch selective sampling based on version space analysis 被引量:4
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作者 张晓宇 《High Technology Letters》 EI CAS 2012年第2期208-213,共6页
A novel dynamic batch selective sampling algorithm based on version space analysis is presented. In the traditional batch selective sampling, example selection is entirely determined by the existing unreliable classif... A novel dynamic batch selective sampling algorithm based on version space analysis is presented. In the traditional batch selective sampling, example selection is entirely determined by the existing unreliable classification boundary; meanwhile, within a batch, examples labeled previously fail to provide instructive information for the selection of the rest. As a result, using the examples selected in batch mode for model refinement will jeopardize the classification performance. Based on the duality between feature space and parameter space under the SVM active learning fi:amework, dynamic batch selective sampling is proposed to address the problem. We select a batch of examples dynamically, using the examples labeled previously as guidance for further selection. In this way, the selection of feedback examples is determined by both the existing classification model and the examples labeled previously. Encouraging experimental results demonstrate the effectiveness of the proposed algorithm. 展开更多
关键词 relevance feedback active learning selective sampling support vector machine(SVM) version space
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Digital Rights Management:Model,Technology and Application 被引量:7
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作者 Zhaofeng Ma 《China Communications》 SCIE CSCD 2017年第6期156-167,共12页
with rapid achievement of current information technology and computing ability and applications,much more digital content such as films,cartoons,design drawings,office documents and software source codes are produced ... with rapid achievement of current information technology and computing ability and applications,much more digital content such as films,cartoons,design drawings,office documents and software source codes are produced in daily work,however to protect the content being copying,shared or deliberately stolen by inside or outside,digital rights management(DRM) became more and more important for digital content protection.In this paper,we studied various DRM model,technology and application,and first proposed DRM Security Infrastructure(DSI),in which we defined encryption,hash,signature algorithm,watermarking algorithms,authentication,usage control,trusted counter,conditional trace,secure payment,and based on the DSI we then proposed a whole classification approach and architecture of all kinds of DRMs,in which we proposed 6 typical classes of copyrights and content protection DRMs architecture:(1) Software-oriented DRM,(2) e Book-oriented DRM,(3) Video-oriented DRM,(4) Image-Oriented DRM(5) Unstructured data oriented DRM,(6) Text-oriented DRM.Based on the above DSI,we then proposed a dynamic DRM model selection method for various DRM application,which can be adapted dynamically for different technology of different applications,which can provide awhole solution for variant DRM development in a rapid and customized mode.The proposed DRM method,technology and application in this paper provided a common,flexible and extendable solution for variant DRM scenes,and can support rapid and customized development.Moreover,we proposed an opinion that the future life will enter into a new era that the content usage and consumption will not again adopt DRM technology rather than with law,liberty and morality. 展开更多
关键词 digital rights management drm security infrastructure ENCRYPTION WATERMARK usage control drm-free
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Numerical Simulation of Asynchronous Simulated Moving Bed Chromatography 被引量:4
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作者 LU Jiangang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2004年第3期415-420,共6页
Asynchronous simulated moving bed chromatography (ASMBC), known also as the 'VARICOL' process, is more efficient and flexible than the well-known and traditional simulated moving bed chromatography (SMBC). A d... Asynchronous simulated moving bed chromatography (ASMBC), known also as the 'VARICOL' process, is more efficient and flexible than the well-known and traditional simulated moving bed chromatography (SMBC). A detailed model of ASMBC, taking account of non-linear competitive isotherms, mass transfer parameters, and complex port switching schedule parameters, was developed to simulate the complex dynamics of ASMBC.The simulated performance is in close agreement with the experimental data of chiral separation reported in the literature. The simulation results show that ASMBC can achieve the performance similar to SMBC with fewer columns and can achieve better performance than SMBC with the same total column number. All design and operation parameters can be chosen correctly by numerical simulation. This detailed ASMBC model and the numerical technique are useful for design, operation, optimization and scale-up of ASMBC. 展开更多
关键词 simulated moving bed chromatography chiral separation numerical simulation Varicol process port switching schedule
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Bibliometric Analysis of Global Research Progress on Coastal Flooding 1995–2016 被引量:2
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作者 GAO Chao RUAN Tian 《Chinese Geographical Science》 SCIE CSCD 2018年第6期998-1008,共11页
Global research progress on coastal flooding was studied using a bibliometric evaluation of publications listed in the Web of Science extended scientific citation index. There was substantial growth in coastal floodin... Global research progress on coastal flooding was studied using a bibliometric evaluation of publications listed in the Web of Science extended scientific citation index. There was substantial growth in coastal flooding research output, with increasing publications, a higher collaboration index, and more references during the 1995–2016 period. The USA has taken a dominant position in coastal flooding research, with the US Geological Survey leading the publications ranking. Research collaborations at institutional scales have become more important than those at global scales. International collaborative publications consistently drew more citations than those from a single country. Furthermore, coastal flooding research included combinations of multi-disciplinary categories, including ‘Geology' and ‘Environmental Sciences & Ecology'. The most important coastal flooding research sites were wetlands and estuaries. While numerical modeling and 3 S(Remote sensing, RS; Geography information systems, GIS; Global positioning systems, GPS) technology were the most commonly used methods for studying coastal flooding, Lidar gained in popularity. The vulnerability and adaptation of coastal environments, their resilience after flooding, and ecosystem services function showed increases in interest. 展开更多
关键词 coastal flood scientific outputs bibliometric analysis research trends Web of Science
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An Assessment of MJO and Tropical Waves Simulated by Different Versions of the GAMIL Model 被引量:3
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作者 MAO Jiang-Yu LI Li-Juan 《Atmospheric and Oceanic Science Letters》 2012年第1期26-31,共6页
Simulated outgoing longwave radiation (OLR) outputs by two versions of the grid-point atmospheric general circulation model (GAMIL) were analyzed to assess the influences of improvements in cloud microphysics and ... Simulated outgoing longwave radiation (OLR) outputs by two versions of the grid-point atmospheric general circulation model (GAMIL) were analyzed to assess the influences of improvements in cloud microphysics and convective parameterization schemes on the simulation of the Madden-Julian oscillation (MJO) and other tropical waves. The wavenumber-frequency spectral analysis was applied to isolate dominant modes of convectively coupled equatorial waves, including the M30, Kelvin, equatorial Rossby (ER), mixed Rossby-gravity (MRG), and inertio-gravity (1G) waves. The performances of different versions of the GAMIL model (version 1.0 (GAMIL1.0) and version 2.0 (GAMIL2.0)) were evalu- ated by comparing the power spectrum distributions of these waves among GAMIL 1.0, GAMIL2.0, and observational data. GAMIL1.0 shows a weak MJO signal, with the maximum variability occurring separately at wavenumbers 1 and 4 rather than being concentrated on wavenumbers 1-3, suggesting that GAMILI.0 could not effectively capture the intraseasonal variability. However, GAMIL2.0 is able to effectively reproduce both the symmetric and anti-symmetric waves, and the significant spectra of the MJO, Kelvin, and MRG waves are in agreement with observational data, indicating that the ability of GAMIL2.0 to simulate the MJO and other tropical waves is enhanced by improving the cloud microphysics and convective parameterization schemes and implying that such improvements are crucial to further improving this model's performance. 展开更多
关键词 GAMIL model MJO tropical waves
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Improving Simulation of the Terrestrial Carbon Cycle of China in Version 4.5 of the Community Land Model Using a Revised V_(cmax) Scheme 被引量:4
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作者 WANG Yuan-Yuan XIE Zheng-Hui +1 位作者 JIA Bing-Hao YU Yan 《Atmospheric and Oceanic Science Letters》 CSCD 2015年第2期88-94,共7页
The maximum rate of carboxylation (Vcax) is a key photosynthetic parameter for gross primary produc- tion (GPP) estimation in terrestrial biosphere models. A set of observation-based Vcax values, which take the ni... The maximum rate of carboxylation (Vcax) is a key photosynthetic parameter for gross primary produc- tion (GPP) estimation in terrestrial biosphere models. A set of observation-based Vcax values, which take the ni- trogen limitation on photosynthetic rates into consideration, are used in version 4.5 of the Community Land Model (CLM4.5). However, CLM4.5 with carbon-nitrogen (CN) biogeochemistry (CLM4.5-CN) still uses an inde- pendent decay coefficient for nitrogen after the photosyn- thesis calculation. This means that the nitrogen limitation on the carbon cycle is accounted for twice when CN bio- geochemistry is active. Therefore, to avoid this double nitrogen down-regulation in CLM4.5-CN, the original Vcmax scheme is revised with a new one that only accounts for the transition between Vcmax and its potential value (without nitrogen limitation). Compared to flux tower- based observations, the new Vcmax scheme reduces the root-mean-square error (RMSE) in GPP for China's Mainland by 13.7 g C m-2 yr-1, with a larger decrease over humid areas (39.2 g C m 2 yr-1). Moreover, net primary production and leaf area index are also improved, with reductions in RMSE by 0.8% and 11.5%, respectively. 展开更多
关键词 CLM4.5 Vcmax gross primary production net primary production leaf area index
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Music on Line or in the City? How Listening to Music Changes Because of Piracy
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作者 Olivier Lefebvre 《Sociology Study》 2012年第9期696-704,共9页
Music has often changed, from a social point of view, and also the relationship between music and the city. This paper attempts to describe how music changes under the impact of Internet. The milieu of musicians and t... Music has often changed, from a social point of view, and also the relationship between music and the city. This paper attempts to describe how music changes under the impact of Internet. The milieu of musicians and the audiences are concerned. The economic model of music has not burst into pieces, but it has deeply changed. There is a trend to pure consumerism thanks to internet (probably the sales of downloaded music will become more and more important). Also, independent artists can use Internet and have a livelihood (fat tail phenomenon). Therefore the diversity of music can be preserved. Concerts (music in the city) allow escaping from the losses of money because of piracy. There are several experiences for listeners, which are possible, some of them involving going to concerts and festivals. 展开更多
关键词 MUSIC Internet PIRACY
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Calculation of impact factor of vibrator oscillation in offset printing based on fuzzy controller and genetic algorithm
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作者 初红艳 Yang Junjing Cai Ligang 《High Technology Letters》 EI CAS 2015年第1期15-21,共7页
In the inking system of an offset printing press,a vibrator roller distributes ink not only in the circumferential direction but also in the axial direction.In the control process,if ink amount is determined only by t... In the inking system of an offset printing press,a vibrator roller distributes ink not only in the circumferential direction but also in the axial direction.In the control process,if ink amount is determined only by the dot area coverage without considering the impact of vibrator roller's oscillation,the printing colour quality will be reduced.This paper describes a method of calculating the impact factor of vibrator roller' s oscillation.First,the oscillation performance is analyzed and sample data of impact factor is got.Then,a fuzzy controller used for the calculation of the impact factor is designed,and genetic algorithm is used to optimize membership functions and obtain the fuzzy control rules automatically.This fuzzy controller can be used to calculate impact factors for any printing condition,and the impact factors can be used for ink amount control in printing process and it is important for higher printing colour quality and lowering ink and paper waste. 展开更多
关键词 offset printing colour quality control impact factor fuzzy control genetic algorithm
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On the prospects of the Quality Education under the Education and Management of Higher VocationalSchools
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作者 HeHUANG 《International Journal of Technology Management》 2014年第11期69-71,共3页
Authors of papers to proceedings have to type these in a form suitable for direct photographic reproduction by the publisher. In order to ensure uniform style throughout the volume, all the papers have to be prepared ... Authors of papers to proceedings have to type these in a form suitable for direct photographic reproduction by the publisher. In order to ensure uniform style throughout the volume, all the papers have to be prepared strictly according to the instructions set below. A laser printer should be used to print the text. The publisher will reduce the camera-ready copy to 75% and print it in black only. For the convenience of the authors template files for MS Word 6.0 (and higher) are provided. 展开更多
关键词 In order to MS Word
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The Theory and Practice of Research-and-Discussion Teaching --Taking the Animation Teaching as an Example
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作者 Wang Rui 《International English Education Research》 2014年第5期32-34,共3页
Along with the support policy for the development of domestic animation by State Administration of Press, Publication, Radio, Film and Television of The People's Republic of China and local governments, the domestic ... Along with the support policy for the development of domestic animation by State Administration of Press, Publication, Radio, Film and Television of The People's Republic of China and local governments, the domestic animation industry has wide development prospects. According to statistics, there are more than 500 colleges and universities opening animation specialty and more than thousands of universities having related courses. But in recent years, there has been a contradictory phenomenon. On one hand, it is really hard for large numbers of graduates to find jobs related to animation. On the other hand, it is difficult for domestic animation enterprises to recruit outstanding animation talents. The main reason for this phenomenon is that the animation education in colleges and universities can not satisfy the demand from market and can not meet the requirements of the animation industry development in china.So we have the necessity to discuss the suitable education mode for animation development. 展开更多
关键词 ANIMATION TEACHING Research-and-Discussion
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Copyright Protection Mode for Geological Information Sharing under the Environment for Network
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作者 Ruixue Jiang 《International English Education Research》 2015年第11期84-86,共3页
Using copyright rules clear government of geological information property rights is the main path to realization of geological information socially sharing. For China's current laws have an institute basic principle ... Using copyright rules clear government of geological information property rights is the main path to realization of geological information socially sharing. For China's current laws have an institute basic principle of geological information protected by copyright law, we need to detailed thinking the copyright subject, write content, licensing and other aspects, combine the geological information sharing mechanism. 展开更多
关键词 Geological Information Property Right Database Right
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Changes of the tropical Pacific Walker circulation simulated by two versions of FGOALS model 被引量:4
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作者 MA ShuangMei ZHOU TianJun 《Science China Earth Sciences》 SCIE EI CAS 2014年第9期2165-2180,共16页
Here we assessed the performances of IAP/LASG climate system model FGOALS-g2 and FGOAS-s2 in the simulation of the tropical Pacific Walker circulation (WC). Both models reasonably reproduce the climatological spatia... Here we assessed the performances of IAP/LASG climate system model FGOALS-g2 and FGOAS-s2 in the simulation of the tropical Pacific Walker circulation (WC). Both models reasonably reproduce the climatological spatial distribution features of the tropical Pacific WC. We also investigated the changes of WC simulated by two versions of FGOALS model and discussed the mechanism responsible for WC changes. Observed Indo-Pacific sea level pressure (SLP) reveals a reduction of WC during 1900-2004 and 1950-2004, and an enhancement of WC during 1982-2004. During the three different time spans, the WC in FGOALS-g2 shows a weakening trend. In FGOALS-s2, tropical Pacific atmospheric circulation shows no significant change over the past century, but the WC strengthens during 1950-2004 and 1982-2004. The simulated bias of the WC change may be related to the phase of the multi-decadal mode in coupled models, which is not in sync with that in the observations. The change of WC is explained by the hydrological cycle constraints that precipitation must be balanced with the moisture trans- porting from the atmospheric boundary layer to the free troposphere. In FGOALS-g2, the increasing amplitude of the relative variability of precipitation (AP/P) is smaller (larger) than the relative variability of moisture (Aq/q) over the tropical western (eastern) Pacific over the three time spans, and thus leads to a weakened WC. In FGOALS-s2, the convective mass exchange fluxes increase (decrease) over the tropical western (eastern) Pacific over the past 53 a (1950-2004) and the last 23 a (1982- 2004), and thus leads to a strengthened WC. The distributions of sea surface temperature (SST) trends dominate the change of WC. Over the past 55 a and 23 a, tropical Pacific SST shows an E1 Nifto-like (a La Nifia-like) trend pattern in FGOALS-g2 (FGOALS-s2), which drives the weakening (strengthening) of WC. Therefore, a successful simulation of the tropical Pacific SST change pattern is necessary for a reasonable simulation of WC change in climate system models. This idea is further sup- ported by the diagnosis of historical sea surface temperature driven AGCM-simulations. 展开更多
关键词 Walker circulation FGOALS-g2 FGOALS-s2 historical climate simulation hydrological cycle constraint SST change pattern AMIP simulation
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Climate sensitivities of two versions of FGOALS model to idealized radiative forcing 被引量:19
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作者 CHEN XiaoLong ZHOU TianJun GUO Zhun 《Science China Earth Sciences》 SCIE EI CAS 2014年第6期1363-1373,共11页
Projections of future climate change by climate system models depend on the sensitivities of models to specified greenhouse gases.To reveal and understand the different climate sensitivities of two versions of LASG/IA... Projections of future climate change by climate system models depend on the sensitivities of models to specified greenhouse gases.To reveal and understand the different climate sensitivities of two versions of LASG/IAP climate system model FGOALS-g2 and FGOALS-s2,we investigate the global mean surface air temperature responses to idealized CO2 forcing by using the output of abruptly quadrupling CO2 experiments.The Gregory-style regression method is used to estimate the"radiative forcing"of quadrupled CO2 and equilibrium sensitivity.The model response is separated into a fast-response stage associated with the CO2 forcing during the first 20 years,and a slow-response stage post the first 20 years.The results show that the radiative forcing of CO2 is overestimated due to the positive water-vapor feedback and underestimated due to the fast cloud processes.The rapid response of water vapor in FGOALS-s2 is responsible for the stronger radiative forcing of CO2.The climate sensitivity,defined as the equilibrium temperature change under doubled CO2 forcing,is about 3.7 K in FGOALS-g2 and4.5 K in FGOALS-s2.The larger sensitivity of FGOALS-s2 is due mainly to the weaker negative longwave clear-sky feedback and stronger positive shortwave clear-sky feedback at the fast-response stage,because of the more rapid response of water vapor increase and sea-ice decrease in FGOALS-s2 than in FGOALS-g2.At the slow-response stage,similar to the fast-response stage,net negative clear-sky feedback is weaker in FGOALS-s2.Nevertheless,the total negative feedback is larger in FGOALS-s2 due to a larger negative shortwave cloud feedback that involves a larger response of total cloud fraction and condensed water path increase.The uncertainties of estimated forcing and net feedback mainly come from the shortwave cloud processes. 展开更多
关键词 climate sensitivity climate response FEEDBACKS FGOALS CMIP5
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Charting brain growth in tandem with brain templates at school age 被引量:4
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作者 Hao-Ming Dong F.Xavier Castellanos +20 位作者 Ning Yang Zhe Zhang Quan Zhou Ye He Lei Zhang Ting Xu Avram J.Holmes B.T.Thomas Yeo Feiyan Chen Bin Wang Christian Beckmann Tonya White Olaf Sporns Jiang Qiu Tingyong Feng Antao Chen Xun Liu Xu Chen Xuchu Weng Michael P.Milham Xi-Nian Zuo 《Science Bulletin》 SCIE EI CAS CSCD 2020年第22期1924-1934,M0004,共12页
Brain growth charts and age-normed brain templates are essential resources for researchers to eventually contribute to the care of individuals with atypical developmental trajectories.The present work generates age-no... Brain growth charts and age-normed brain templates are essential resources for researchers to eventually contribute to the care of individuals with atypical developmental trajectories.The present work generates age-normed brain templates for children and adolescents at one-year intervals and the corresponding growth charts to investigate the influences of age and ethnicity using a common pediatric neuroimaging protocol.Two accelerated longitudinal cohorts with the identical experimental design were implemented in the United States and China.Anatomical magnetic resonance imaging(MRI)of typically developing school-age children(TDC)was obtained up to three times at nominal intervals of1.25 years.The protocol generated and compared population-and age-specific brain templates and growth charts,respectively.A total of 674 Chinese pediatric MRI scans were obtained from 457 Chinese TDC and 190 American pediatric MRI scans were obtained from 133 American TDC.Population-and age-specific brain templates were used to quantify warp cost,the differences between individual brains and brain templates.Volumetric growth charts for labeled brain network areas were generated.Shape analyses of cost functions supported the necessity of age-specific and ethnicitymatched brain templates,which was confirmed by growth chart analyses.These analyses revealed volumetric growth differences between the two ethnicities primarily in lateral frontal and parietal areas,regions which are most variable across individuals in regard to their structure and function.Age-and ethnicity-specific brain templates facilitate establishing unbiased pediatric brain growth charts,indicating the necessity of the brain charts and brain templates generated in tandem.These templates and growth charts as well as related codes have been made freely available to the public for open neuroscience(https://github.com/zuoxinian/CCS/tree/master/H3/Growth Charts). 展开更多
关键词 Growth charts NEUROIMAGING ETHNICITY Brain templates DEVELOPMENT
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An analytical study of drug release kinetics from a degradable polymeric matrix 被引量:1
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作者 Koyel Chakravarty D. C. Dalal 《International Journal of Biomathematics》 SCIE 2018年第1期255-277,共23页
In modern days, biodegradable polymeric matrix used as the kingpin of local drug delivery system is in the center of attention. This work is concentrated on the formulation of mathematical model elucidating degradatio... In modern days, biodegradable polymeric matrix used as the kingpin of local drug delivery system is in the center of attention. This work is concentrated on the formulation of mathematical model elucidating degradation of drug-loaded polymeric matrix followed by drug release to the adjacent biological tissues. Polymeric degradation is penciled with mass conservation equations. Drug release phenomenon is modeled by considering solubilization dynamics of drug particles, diffusion of the solubilized drug through polymeric matrix along with reversible dissociation/recrystallization process. In the tissue phase, reversible dissociation/association along with internalization processes of drug are taken into account. For this, a two-phase spatio-temporal model is postu- lated, which has ensued to a system of partial differential equations. They are solved analytically with appropriate choice of initial, interface and boundary conditions. In order to reflect the potency of the advocated model, the simulated results are analogized with corresponding experimental data and found laudable agreement so as to validate the applicability of the model considered. This model seems to foster the delicacy of the mantle enacted by important drug kinetic parameters such as diffusion coefficients, mass transfer coefficients, particle binding and internalization parameters, which is illustrated through local sensitivity analysis. 展开更多
关键词 SOLUBILIZATION INTERNALIZATION tissues.
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