Nanoparticles drug delivery system has sustained and controlled release features as well as targeted drug delivery, which can change the characteristics of drug distribution in vivo. It can increase the stability of t...Nanoparticles drug delivery system has sustained and controlled release features as well as targeted drug delivery, which can change the characteristics of drug distribution in vivo. It can increase the stability of the drug and enhance drug bioavailability. The selective targeting of nanoparticles can be achieved through enhanced permeability and retention effect and a conjugated specific ligand or through the effects of physiological conditions, such as pH and temperature. Nanoparticles can be prepared by using a wide range of materials and can be used to encapsulate chemotherapeutic agents to reduce toxicity, which can be used for imaging, therapy, and diagnosis. In this research, recent progress on nanoparticles as a targeted drug delivery system will be reviewed, including positive-targeting, negative-targeting, and physicochemical-targeting used as anticancer drug carriers.展开更多
Inorganic lead halide perovskite CsPbBr3 offers attractive photophysical properties and phase stability for high-performance optoelectronic devices.However,CsPbBr3 films produced by the classic solution-based two-step...Inorganic lead halide perovskite CsPbBr3 offers attractive photophysical properties and phase stability for high-performance optoelectronic devices.However,CsPbBr3 films produced by the classic solution-based two-step method are always accompanied with impurity phases of CsPb2Br5 and Cs4PbBr6,which represents a major efficiency-limiting factor for future advances of CsPbBr3-based devices.The challenge lies in the complexity of the Cs-Pb-Br phase system,requiring both spatially and temporally precise control of the precursor stoichiometry during solution-phase growth of CsPbBr3 films.By adopting 2-methoxyethanol as the solution conversion medium instead of commonly applied methanol,the reaction between CsBr and PbBr2 can be finely controlled to yield single phase CsPbBr3 films within a few minutes;extending the solution-conversion step to 24 h does not alter the phase purity of resulting CsPbBr3 films.The present work paves the way to regulate the crystal growth behaviors of two-step solution-processed CsPbBr3 films by simple solvent engineering.展开更多
We reported here the fabrication of the elec- trically tunable infrared (IR) reflectors based on the polymer stabilized cholesteric liquid crystal (PSCLC) with negative dielectric anisotropy. A systematic study of...We reported here the fabrication of the elec- trically tunable infrared (IR) reflectors based on the polymer stabilized cholesteric liquid crystal (PSCLC) with negative dielectric anisotropy. A systematic study of the influence of cell gap on the electrically tunable reflection bandwidth was performed. When a direct current (DC) electric field was ap- plied, the reflection bandwidth red shifted in the cells with small cell gap, whereas the bandwidth broadening was ob- served in the cells with large cell gap. It is therefore reasonable to deduct that the reflection is dictated by the pitch gradient steepness which strongly relies on the cell thickness. The re- sults reveal that for making PSCLC based IR reflector windows with electrically induced bandwidth broadening, a minimal cell gap thickness is required. The resulted IR reflectors pos- sess a short native switching time and long-term operation stability, and are potentially applicable as smart energy saving windows in buildings and automobiles.展开更多
In this paper, we propose and analyze a three-species predator prey system in the presence of additional food for top predator. It is assumed that the middle predator is acting as a prey as well as a predator and the ...In this paper, we propose and analyze a three-species predator prey system in the presence of additional food for top predator. It is assumed that the middle predator is acting as a prey as well as a predator and the top predator consumes both prey as well as middle predator. It is also considered that a constant amount of additional food for top predator exists in the ecosystem. The effects of harvesting of top predator are investigated. The existence and stability conditions of the equilibria have been discussed analytically. The Hopf bifurcation analysis of the system with respect to predation rate of prey to the top predator and the harvesting effort have been analyzed both analytically and numerically. Pontryagin's maximum principle is used to determine the optimal harvesting of top predator population to maximize the discounted net revenue. From our analysis, it is seen that the additional food has a significant impact to prevent the extinction risk of top predator population and also to increase revenue collection. Finally, some numerical results have been given in support of our analytical findings.展开更多
In this paper, we investigate the dynamical behavior of a fractional order phytoplankton- zooplankton system. In this paper, stability analysis of the phytoplankton zooplankton model (PZM) is studied by using the fr...In this paper, we investigate the dynamical behavior of a fractional order phytoplankton- zooplankton system. In this paper, stability analysis of the phytoplankton zooplankton model (PZM) is studied by using the fractional Routh-Hurwitz stability conditions. We have studied the local stability of the equilibrium points of PZM. We applied an efficient numerical method based on converting the fractional derivative to integer derivative to solve the PZM.展开更多
基金Supported by a grant from the foundation of Guangzhou Municipal Key Project for Special Scientific Plan(No.2008A1-E4101)
文摘Nanoparticles drug delivery system has sustained and controlled release features as well as targeted drug delivery, which can change the characteristics of drug distribution in vivo. It can increase the stability of the drug and enhance drug bioavailability. The selective targeting of nanoparticles can be achieved through enhanced permeability and retention effect and a conjugated specific ligand or through the effects of physiological conditions, such as pH and temperature. Nanoparticles can be prepared by using a wide range of materials and can be used to encapsulate chemotherapeutic agents to reduce toxicity, which can be used for imaging, therapy, and diagnosis. In this research, recent progress on nanoparticles as a targeted drug delivery system will be reviewed, including positive-targeting, negative-targeting, and physicochemical-targeting used as anticancer drug carriers.
基金supported by the National Key Research and Development Program of China(2018YFA0209303)the National Natural Science Foundation of China(U1663228,51902153,and 51972165)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions。
文摘Inorganic lead halide perovskite CsPbBr3 offers attractive photophysical properties and phase stability for high-performance optoelectronic devices.However,CsPbBr3 films produced by the classic solution-based two-step method are always accompanied with impurity phases of CsPb2Br5 and Cs4PbBr6,which represents a major efficiency-limiting factor for future advances of CsPbBr3-based devices.The challenge lies in the complexity of the Cs-Pb-Br phase system,requiring both spatially and temporally precise control of the precursor stoichiometry during solution-phase growth of CsPbBr3 films.By adopting 2-methoxyethanol as the solution conversion medium instead of commonly applied methanol,the reaction between CsBr and PbBr2 can be finely controlled to yield single phase CsPbBr3 films within a few minutes;extending the solution-conversion step to 24 h does not alter the phase purity of resulting CsPbBr3 films.The present work paves the way to regulate the crystal growth behaviors of two-step solution-processed CsPbBr3 films by simple solvent engineering.
基金supported by the National Natural Science Foundation of China (51503070, 51561135014, U1501244)Guangdong Innovative Research Team Program (2013C102)+3 种基金Science and technology project of Guangdong Province (2015B090913004, 2016B090909001)Science and technology Project of Shenzhen (JSGG201704143009027)Guangdong Provincial Key Laboratory of Optical Information Materials and Technology (2017B030301007)the 111 Project
文摘We reported here the fabrication of the elec- trically tunable infrared (IR) reflectors based on the polymer stabilized cholesteric liquid crystal (PSCLC) with negative dielectric anisotropy. A systematic study of the influence of cell gap on the electrically tunable reflection bandwidth was performed. When a direct current (DC) electric field was ap- plied, the reflection bandwidth red shifted in the cells with small cell gap, whereas the bandwidth broadening was ob- served in the cells with large cell gap. It is therefore reasonable to deduct that the reflection is dictated by the pitch gradient steepness which strongly relies on the cell thickness. The re- sults reveal that for making PSCLC based IR reflector windows with electrically induced bandwidth broadening, a minimal cell gap thickness is required. The resulted IR reflectors pos- sess a short native switching time and long-term operation stability, and are potentially applicable as smart energy saving windows in buildings and automobiles.
文摘In this paper, we propose and analyze a three-species predator prey system in the presence of additional food for top predator. It is assumed that the middle predator is acting as a prey as well as a predator and the top predator consumes both prey as well as middle predator. It is also considered that a constant amount of additional food for top predator exists in the ecosystem. The effects of harvesting of top predator are investigated. The existence and stability conditions of the equilibria have been discussed analytically. The Hopf bifurcation analysis of the system with respect to predation rate of prey to the top predator and the harvesting effort have been analyzed both analytically and numerically. Pontryagin's maximum principle is used to determine the optimal harvesting of top predator population to maximize the discounted net revenue. From our analysis, it is seen that the additional food has a significant impact to prevent the extinction risk of top predator population and also to increase revenue collection. Finally, some numerical results have been given in support of our analytical findings.
文摘In this paper, we investigate the dynamical behavior of a fractional order phytoplankton- zooplankton system. In this paper, stability analysis of the phytoplankton zooplankton model (PZM) is studied by using the fractional Routh-Hurwitz stability conditions. We have studied the local stability of the equilibrium points of PZM. We applied an efficient numerical method based on converting the fractional derivative to integer derivative to solve the PZM.