Laser-weldable Sip-SiCp/Al hybrid composites with high volume fraction （60%-65%） of SiC reinforcement were fabricated by compression moulding and vacuum gas pressure infiltration technology. Microscopic observation ...Laser-weldable Sip-SiCp/Al hybrid composites with high volume fraction （60%-65%） of SiC reinforcement were fabricated by compression moulding and vacuum gas pressure infiltration technology. Microscopic observation displayed that the Sip-SiCp/Al hybrid composites with bilayer structure were compact without gas pores and the intergradation between Sip/Al layer and SiCp/Al layer was homogeneous and continuous. Further investigation revealed that the Sip-SiCp/Al hybrid composites possessed low density （2.96 g/cm^3）, high gas tightness （1.0 mPa·cm^3）/s）, excellent thermal management function as a result of high thermal conductivity （194 W/（m·K） and low coefficient of thermal expansion （7.0×10^-6 K-1）. Additionally, Sip-SiCp/Al hybrid composites had outstanding laser welding adaptability, which is significantly important for electronic packaging applications. The gas tightness of components after laser welding （48 mPa·cm^3）/s） can well match the requirement of advanced electronic packaging. Several kinds of these precision components passed tests and were put into production.展开更多
Human serum albumin(HSA)is the most abundant plasma protein and has an inherent ability to target tumor cells.It is an excellent candidate for drug delivery.However,HSA cannot form complex with DNA or RNA,because it i...Human serum albumin(HSA)is the most abundant plasma protein and has an inherent ability to target tumor cells.It is an excellent candidate for drug delivery.However,HSA cannot form complex with DNA or RNA,because it is negatively charged under physiological conditions.In this work,we reported a simple method to prepare HSA/RNA nanoparticles mainly by physical interaction.Firstly,the solution p H is adjusted to 4.0,under which condition HSA is positively charged.It forms complex with RNA via electrostatic interaction.The solution is then heated at 75 oC for 15 min to stabilize the structure and the size of the formed complex.The HSA/RNA nanoparticle prepared by this method has a diameter about 110 nm and a narrow distribution.It is also stable for days under physiological conditions.Cellular essays demonstrate that these particles exhibit a high cellular uptake efficiency and non-toxicity to He La cells.展开更多
Materials science is an interdisciplinary field applying the properties of matter to various areas of science and engineering. This scientific field investigates the relationship between the structure of materials at ...Materials science is an interdisciplinary field applying the properties of matter to various areas of science and engineering. This scientific field investigates the relationship between the structure of materials at atomic or molecular scales and their macroscopic properties. It incorporates elements of applied physics and chemistry. With significant media attention focused on nanoscience and nanotechnology in recent years, materials science has been propelled to the forefront at many universities. Materials science encompasses various classes of materials, including electronic materials, functional ceramics, magnesium, material and processes for flat-panel displays, eco/environmental materials, sustainable energy materials, transportation materials, electronic packaging materials, etc.展开更多
文摘Laser-weldable Sip-SiCp/Al hybrid composites with high volume fraction （60%-65%） of SiC reinforcement were fabricated by compression moulding and vacuum gas pressure infiltration technology. Microscopic observation displayed that the Sip-SiCp/Al hybrid composites with bilayer structure were compact without gas pores and the intergradation between Sip/Al layer and SiCp/Al layer was homogeneous and continuous. Further investigation revealed that the Sip-SiCp/Al hybrid composites possessed low density （2.96 g/cm^3）, high gas tightness （1.0 mPa·cm^3）/s）, excellent thermal management function as a result of high thermal conductivity （194 W/（m·K） and low coefficient of thermal expansion （7.0×10^-6 K-1）. Additionally, Sip-SiCp/Al hybrid composites had outstanding laser welding adaptability, which is significantly important for electronic packaging applications. The gas tightness of components after laser welding （48 mPa·cm^3）/s） can well match the requirement of advanced electronic packaging. Several kinds of these precision components passed tests and were put into production.
基金the National Natural Science Foundation of China (21574002)
文摘Human serum albumin(HSA)is the most abundant plasma protein and has an inherent ability to target tumor cells.It is an excellent candidate for drug delivery.However,HSA cannot form complex with DNA or RNA,because it is negatively charged under physiological conditions.In this work,we reported a simple method to prepare HSA/RNA nanoparticles mainly by physical interaction.Firstly,the solution p H is adjusted to 4.0,under which condition HSA is positively charged.It forms complex with RNA via electrostatic interaction.The solution is then heated at 75 oC for 15 min to stabilize the structure and the size of the formed complex.The HSA/RNA nanoparticle prepared by this method has a diameter about 110 nm and a narrow distribution.It is also stable for days under physiological conditions.Cellular essays demonstrate that these particles exhibit a high cellular uptake efficiency and non-toxicity to He La cells.
文摘Materials science is an interdisciplinary field applying the properties of matter to various areas of science and engineering. This scientific field investigates the relationship between the structure of materials at atomic or molecular scales and their macroscopic properties. It incorporates elements of applied physics and chemistry. With significant media attention focused on nanoscience and nanotechnology in recent years, materials science has been propelled to the forefront at many universities. Materials science encompasses various classes of materials, including electronic materials, functional ceramics, magnesium, material and processes for flat-panel displays, eco/environmental materials, sustainable energy materials, transportation materials, electronic packaging materials, etc.
