玄参中一个新的环烯醚萜糖苷化合物

从玄参 Scrophularia ningpoensis根的乙醇提取物中分得 13个化合物 ,经理化性质和光谱分析 ,分别鉴定为 :β-谷甾醇 ( )、肉桂酸 ( )、β-谷甾醇 - 3- O- β- D-吡喃葡萄糖苷 ( )、ningpogenin( )、6′- O-乙酰哈巴苷 ( )、哈巴苷 ( )、京尼平苷 ( )、毛蕊花苷 ( )、安格洛苷 C( )、爪钩草苷 ( )、葡萄糖 ( )、果糖 ( )和蔗糖 ( )。其中 为新化合物 , 和 为首次从玄参中得到。同时 ,全归属了 6′- O-乙酰哈巴苷的碳和氢信号。

Iridoid Glycosides from Buddleja lindeyana

Aim To study the chemical constituents of Buddleja lindeyana. Methods The constituents were separated and purified by different methods of chromatography, and their structures were elucidated by IR, MS and NMR. Results Three iridoid glycosides and two other compounds were isolated from Buddleja lindeyana. Their structures were elucidated to be 6-O-feruloylajugol ( 1 ), erythro-6-oxo-4′-( 3-methoxyl-4-hydroxyphenylglycol-8')-feruloylaj-ugol ( 2 ), threo-6-oxo-4′-(3-methoxyl-4-hydroxyphenylglycol-8')-feruloylajugol ( 3 ), tetra-cosanoic acid 2,3-dihydroxypropyl ester (4), and galactitol (5). Conclusion All the compounds have been isolated from this plant for the first time. Compounds 1, 2 and 3 have protective effect agains MPP+ -induced apoptosis.