An efficient route to macrocyclic polymers via “click” cyclization was presented.The α-bromine and ω-alkyne PMMA were prepared using the standard ATRP technique,initiated with propargyl 2-bromoisobutyrate,Cu(Ⅰ)Br...An efficient route to macrocyclic polymers via “click” cyclization was presented.The α-bromine and ω-alkyne PMMA were prepared using the standard ATRP technique,initiated with propargyl 2-bromoisobutyrate,Cu(Ⅰ)Br and N,N,N’,N″,N-pentamethyldiethylenetriamine(PMDETA).Azidation of the terminal bromine was followed in DMF with sodium azide,and α-azide,ω-alkyne PMMA precursor was obtained.Then the “click” cylcization of precursor between terminal azide and alkyne was carried out under the catalysis of CuBr/PMDETA,during the course of the reaction,a pseudo-high dilution technique was utilized to ensure the favored intramolecular cylcization.The nearly complete cylcization has been confirmed by a combination of IR,1H NMR and GPC analysis,and cyclo-PMMA with an Mn of 15000,PDI of 1.38 was obtained.展开更多
文摘An efficient route to macrocyclic polymers via “click” cyclization was presented.The α-bromine and ω-alkyne PMMA were prepared using the standard ATRP technique,initiated with propargyl 2-bromoisobutyrate,Cu(Ⅰ)Br and N,N,N’,N″,N-pentamethyldiethylenetriamine(PMDETA).Azidation of the terminal bromine was followed in DMF with sodium azide,and α-azide,ω-alkyne PMMA precursor was obtained.Then the “click” cylcization of precursor between terminal azide and alkyne was carried out under the catalysis of CuBr/PMDETA,during the course of the reaction,a pseudo-high dilution technique was utilized to ensure the favored intramolecular cylcization.The nearly complete cylcization has been confirmed by a combination of IR,1H NMR and GPC analysis,and cyclo-PMMA with an Mn of 15000,PDI of 1.38 was obtained.
