卵巢环管性索间质瘤

卵巢环管性索间质瘤多数为良性,部分为低度恶性,具有独特的简单或复杂的环管状结构,可分泌雌、孕激素。临床表现为雌、孕激素分泌过多,以手术切除效果最佳,预后较好。

Ecosystem health: ecological sustainability target of strategic environment assessment

Strategic environment assessment (SEA) and ecosystem health are two new ideas on environmental management. On the basis of reviewing some relevant literature, this paper made discussions on the ecological sustainability target of SEA, the content of ecosystem health as well as the interrelations between SEA and ecosystem health. For a good SEA, its ecological sustainability principles should be provided with distinct content and a general assessment system. A framework for ecosystem health assessment was established according to the content of ecosystem health, and combined into SEA as SEA抯 ecological sustainability target, we can effectively guide decision-makers to make suitable indigenous means and local solutions. , The basic principles and procedure of SEA for ecosystem health are also discussed in the paper.

Coronary collateral circulation： Effects on outcomes of acute anterior myocardial infarction after primary percutaneous coronary intervention

Background To investigate the effects of collateral coronary circulation on the outcome of the patients with anterior myocardial infarction （MI） with left anterior desending artery occlusion abruptly. Methods Data of 189 patients with acute anterior MI who had a primary percutaneous coronary intervention （PCI） in the first 12 h from the onset of symptoms between January 2004 and December 2008 were retrospective analyzed. Left anterior descending arteries （LAD） of all patients were occluded. LADs were reopened with primary PCI. According to the collateral circulation, all patients were classified to two groups： no collateral group （n = 111）, patients without angiographic collateral filling of LAD or side branches （collateral index 0） and collateral group （n = 78）, and patients with angiographic collateral filling of LAD or side branches （collateral index 1, 2 or 3）. At one year＇ s follow-up, the occurrence of death, reinfarctlon, stent thrombosis （ST）, target vessel revascularization and readmission because of heart failure were observed. Results At one year, the mortality was lower in patients with collateral circulation compared with those without collateral circulation （1% vs. 8%, P = 0.049）, whereas there Were no differences in the occurrence of reinfarction, ST, target vessel revascularization and readmission because of heart failure. The occurrence of composite of endpoint was lower in patients with collateral circulation compared with those without collateral circulation （12% vs. 26%; P = 0.014）. Conclusions Pre-exist collateral circulation may prefigure the satisfactory prognosis to the patients with acute anterior MI after primary PCI in the first 12 h of MI onset.

Research progress of vasculopathy in portal hypertension

Portal hypertension, one of the vascular diseases, not only has lesions in liver, but also changes in vascular structures and functions of extrahepatic portal system, systemic system and pulmonary drculation. The pabhological changes of vasculopathy in portal hypertension include remodeling of arterialized visceral veins, intimal injury of visceral veins and destruction of contractile structure in visceral arterial wall. The mechanisms of vasculopathy in portal hypertension may be attributed to the changes of hemodynamics in portal system, immune response, gene modulation, vasoactive substances, and intrahepatic blood flow resistance. Portal hypertension can cause visceral hyperdynamic circulation, and the development and progression of visceral vasculopathy, while visceral vasculopathy can promote the development and progression of portal hypertension and visceral hyperdynamic circulation in turn. The aforementioned three factors interact in the pathogenesis of hepatic cirrhosisinduced portal hypertension and are involved in hemorrhage due to varicose vein rupture.

Chiral Separation of Chlorpheniramine by Capillary Electrophoresis *L

Aim To study the chiral separation of chlorpheniramine(Chp) by using a mixture of β CD and glutamate β CD as the chiral additive in CE. Methods Mixture of β cyclodextrin and glutamate β cyclodextrin was used as a chiral selector to the separation of chlorpheniramine. The effects of the concentrations of β cyclodextrin and glutamate β cyclodextrin, the voltage and the pH of buffers on the separation of chlorpheniramine were studied. Results The chiral recognization of the mixed chiral selector was better than that of a single selector. At pH below 4, the pH of buffers did not affect the separation and the separation of chlorpheniramine had good reproducibility. Conclusion Using a mixture of β CD and Glu β CD as chiral selector is useful for the enantioseparation of Chp in CE.

A discussion of the risks and benefits of using rock terracing to limit soil erosion in Guizhou Province

The construction of stone terraces to minimise soil erosion is common throughout Guizhou. This technique, however, has high inherent risk. Stone terraces are usually much higher than those with earth risers. While they trap a greater thickness of soil on the slope they increase the risk of slope failures, reduce moisture and nutrient availability to plants, and thin more soil up slope. The stone risers also threaten long-term productivity. When a riser collapses debris is deposited over the terrace below making farming difficult. These breaches in the terrace focus surface runoff leading to gully formation and increased sediment transport down slope. Artificial drainage systems, often used in conjunction with terracing, compound the risk. These channels prevent precipitation from soaking into the soil. This limits groundwater and soil moisture recharge which reduces the availability of water for crops and the length of the growing season. The rapid drainage of water from the slope reduces the time of concentration of the catchment resulting in an increase in flood activity. Floods are caused by smaller rainstorm events. They arrive faster and peak quicker and higher than before the channels were constructed. Engineering solutions to soil erosion must therefore be used in conjunction with, and are not as a substitute for, good land management strategies. Furthermore, despite changes in land use practices, and the application of new technologies, there is a maximum amount of production that can be obtained from this land on a sustainable basis.

Heat transfer characteristics of nanofluid through circular tube

Nano fluid is considered to be a class of high efficient heat transfer fluid created by dispersing some special solid nanoparticles (normally less than 100 nm) in traditional heat transfer fluid. The present experiment was conducted aiming at investigating the forced heat transfer characteristics of aqueous copper (Cu) nanofluid at varying concentration of Cu nano-particles in different flow regimes (300<Re≤16 000). The forced convective heat transfer enhancement is available both in the laminar and turbulent flow with increasing the concentration. Especially, the enhancement rate increases dramatically in laminar flow regime, for instance, the heat transfer coefficient of Cu/water nanofluid increases by two times at around Re=2 000 compared with that of base fluid water, and averagely increases by 62% at 1% volume fraction. However, the heat transfer coefficient of Cu/water decreases sharply in the transition flow regime. Furthermore, it has the trend that the heat transfer coefficient displays worse with increasing the concentration.

Management of Crohn’s disease in smokers:Is an alternative approach necessary?

Inflammatory bowel disease(IBD) is a chronic condition with a pathogenic background that involves both genetic and environmental factors.Although important progress has been made regarding the former in the last decade,scarce knowledge is available for the latter.In this sense,smoking remains the most important environmental factor in IBD.Active smoking increases the risk of developing Crohn's disease(CD).Moreover,CD patients who start or continue smoking after disease diagnosis are at risk for poorer outcomes such as higher therapeutic requirements and disease-related complications,as compared to those patients who quit smoking or who never smoked.However,the harmful effect of active smoking is not uniform in all patients or in all clinical scenarios.Interventions designed to facilitate smoking cessation may impact the course of the disease.In this article,the available evidence of the deleterious effects of smoking on CD is reviewed in detail,and alternative therapeutic approaches to CD in smokers are proposed.

Deteriorated function of cutaneous microcirculation in chronic congestive heart failure

Background Chronic congestive heart failure is a complex condition that leads to dysfunction in the peripheral microcirculation. We have previously shown that vascular reactivity is reduced with increasing age. In this study, we examined a group of very old patients with severe chronic heart failure to test the hypothesis that vascular function is further compromised by a combination of heart failure and aging. Methods Cutaneous forearm blood flow was measured by laser Doppler flowmetry and compared among three groups： Group 1 （n = 20, mean ±SE： 85.5 ±4 years）, heart failure patients with New York Heart Association class Ⅳ （NYHA Ⅳ） and with a NT-proBNP level ≥5000 ng/L; Group 2 （n = 15, mean ±SE： 76.5 ±2 years）, heart failure patients with NYHA II and NT-proBNP ≤2000 ng/L, and Group 3 （n = 10, mean ±SE： 67.6 ±3.0 years）, healthy controls with no clinical signs of heart failure. The vasodilator response to the iontophoretic administration of acetylcholine （ACh）, acting via an endothelial mechanism, and sodium nitroprusside （SNP）, acting via a smooth muscle cell mechanism, were studied. Results All patients with heart failure had significantly reduced vascular reactivity independent of the mode of stimulation （ACh, SNP or heat） when compared to healthy controls. However, the responses did not differ between the two groups of heart failure patients. Conclusions Cutaneous vascular reactivity is reduced in heart failure patients and does not correlate with the severity of the condition or age of patients.

3D numerical study on flow structure and heat transfer in a circular tube with V-baffles

A 3D numerical investigation has been carried out to examine periodic laminar flow and heat transfer characteristics in a circular tube with 45°V-baffles with isothermal wall.The computations are based on the finite volume method(FVM),and the SIMPLE algorithm has been implemented.The fluid flow and heat transfer characteristics are presented for Reynolds numbers ranging from 100 to 2000.To generate main longitudinal vortex flows through the tested section,V-baffles with an attack angle of 45°are mounted in tandem and in-line arrangement on the opposite positions of the circular tube.Effects of tube blockage ratio,flow direction on heat transfer and pressure drop in the tube are studied.It is apparent that a pair of longitudinal twisted vortices(P-vortex)created by a V-baffle can induce impingement on a wall of the inter-baffle cavity and lead a drastic increase in heat transfer rate at tube wall.In addition,the larger blockage ratio results in the higher Nusselt number and friction factor values.The computational results show that the optimum thermal enhancement factor is around 3.20 at baffle height of B=0.20 and B=0.25 times of the tube diameter for the V-upstream and V-downstream,respectively.

Sex Determination Mechanisms in Fish

In fish,sex determination(SD) system shows high variation. The SD mechanisms include environmental and genetic regulation. The research on SD system and related genes in intensively studied fish species was reviewed. Although some genes have been described as sex-related,only DMRT1bY can be considered as a master sex determination gene and none of them has been utilized in aquaculture. The variation of fish SD system,the importance of sex-related genes in evolution research and the relations between environmental factors and sex-related genes were also discussed. The fish sex determination mechanism remains largely unknown. Further research needs to be done considering the significance of fish SD studies in basic and applied aspects.

Investigation on adsorption and regeneration performances of multi-walled carbon nanotubes by supercritical water technique

In this paper, adsorption and regeneration characteristics of multi-walled carbon nanotubes （MWNTs） used as adsorbent were investigated for the removal of 1,3-beuzenediol （BDO） from water by the supercritieal water （SCW） technique. FFIR, XPS, SEM and dispersion stability tests were used to characterize the structure and surface morphology of CNTs. The results showed that CNTs surfaces were slightly activated and strongly etched in supercritieal water system. The adsorption capacity of SCW-treated CNTs was higher than that of raw CNTs. The adsorbed amounts for treated CNTs and raw CNTs samples at the same initial concentration of 60 mg/L were ca. 16.42 and 7.30 mg/g, respectively. The BDO adsorption of treated CNTs was due to the physical adsorption. The experimental data fit Freundlich isotherm model better than Langmuir one. The loaded adsorbent could be efficiently desorbed and regenerated by SCW technique. Therefore, SCW is a promising and environmentally friendly technique for the improvement of adsorption and regeneration of CNTs.

Directional drilling in unstable environments

Directional drilling has been established in the coal industry as a viable means of gas drainage, exploration and water management. But the environment in and around coal seams is not always conducive to stable conditions while drilling and borehole stability after the drilling has been completed. This paper identifies the conditions which cause unstable drilling conditions and the various means which are used to attempt to manage or bypass those conditions. Ultimately, equipment does become bogged in these adverse environments and requires recovery by over-coring.

Creating a Geographical Observatory of Atmospheric Pollution （GEOAP） for the Greek Territory

The main purpose of this paper is to analyze the necessity of a Geographical Observatory of Atmospheric Pollution （GEOAP） in the Greek territory. The analysis performed is mainly focused on the benefits of the future function of the GEOAP to the environmental planning of the country and it could also provide an environmental management tool for the whole region. Measuring and mapping the pollution data and at the same time performing the geographical analysis of the complexity and the characteristics of natural and human environment can be useful tool in observation, management, and planning of the environmental policy of the country.

Significant Effects of Fishing Gear Selectivity on Fish Life History

Over the past few decades, extreme changes have occurred in the characters of exploited fish populations. The majority of these changes have affected the growth traits of fish life history, which include a smaller size-at-age, an earlier age-at-maturation and among others. Currently, the causes of these life history traits changes still require systematic analyses and empirical studies. The explanations that have been cited are merely expressed in terms of fish phenotypic adaptation. It has been claimed that the original traits of fish can be recovered once the intensity of exploitation of the fish is controlled. Sustained environmental and fishing pressure will change the life history traits of most fish species, so the fish individual's traits are still in small size-at-age and at earlier age-at-maturation in exploited fish populations. In this paper, we expressed our view of points that fishing gear has imposed selectivity on fish populations and individuals as various other environmental factors have done and such changes are unrecoverable. According to the existing tend of exploited fish individual's life history traits, we suggested further researches in this field and provided better methods of fishery management and thereby fishery resources protection than those available early.

Proper Management of Standards Formulation for Marine Survey Instrument Products

The challenges of the ocean working environment and conditions require that marine instrumentsand equipment be highly reliable and environmentally adaptable.The various parts and componentsof marine instruments should be interchangeable,so as to reduce product costs and reasonably economizethe use of energy and material resources.This paper intruduces the importance of formulating marine instrumentproduct standards,the present conditions and problems of marine product standards,and proposesrelated measures and suggestions to sovle the problems.

A case of transcatheter closure of aortopulmonary window using modified double-disk occluder

Aortopuhnonary window is a rare congenital cardiac malformation, which is previously repaired using cardiopulmonary bypass. However, some cases were reported to repair the aortopulmonary septal defect by transcathetcr closure. Here we present a 30 year-old woman with a 7-mm aortopulmonary window, who was successfully treated using a modified double-disk PmVSD occluder

Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma

AIM： TO determine whether -1195 A→G and/or -765 G→C polymorphisms in Cyclooxygenase-2 CCOX-2） may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population. METHODS： Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area. DNA was isolated from whole blood and used for genotyping. PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis. Odds ratios （OR） and 95% confidence intervals （CI） were estimated. RESULTS： The distribution of the -1195A→G polymorphism was significantly different in esophageal cancer patients compared to controls. The -1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma （OR = 3.85, 95% CI： 1.45-10.3） compared with the -1195AA genotype as a reference. The -765 G→C genotype distribution was not different between the two groups. The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls （OR = 3.45, 95% CI： 1.24-9.58; with AG/AG as a reference）. The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical significance. CONCLUSION： Presence of the COX-2 -1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.

China's Industrial Economy Evolves into an Era of Steady Progress:Prospects and Challenges

China's industrial economy's.growth has steadily evolved into a period of slowdown but the development momentum of its industrialization and urbanization requires and supports a relatively high rate of growth of the industry.Rapid growth has transformed into an era of "steady progress ".That heralds great changes in the momentum of growth,the nature of institutional systems,and policy concepts of the industrial economy.The character of industry and the achievement of healthy development are the essence of industrial advancement in the era. "Steady progress" requires a stabilization of attitude,policy and expectation. "Progress " calls for better quality of growth,equilibrium and environmental performance.Above all,advancing reforms is fundamental to achieving these new objectives of the "steady progress ".As market is potentially powerful while government's function is limited,only moderate,prudent and cautious government regulation will provide the reliable policy assurances necessary to set China's economy firmly on the track of steady progress and sustainable growth.

The degradation of organophosphorus pesticides by means of sodium percarbonate

The factors and mechanisms of oxidative degradation of three organophosphorus pesticides （dichlorvos, methamidophos and phoxim） were studied with sodium percarbonate （SPC） as a solid oxidant. The result showed that SPC has highly activity in degrading these organophosphous pesticides. The most efficient degradation of pesticides occurred under basic conditions and the degradation rates increased with time extension and high temperature. The degradation of organophosphorus pesticides was expected to get even better results at lower initial concentration. Furthermore, we analyzed the intermediate products by NMP, spectrometry. On the basis of the analytical result, the oxidative degradation mechanism was proposed for each organophosphous pesticide. It is significant to understand the environment chemistry of organophosphorus pesticides in environmental system.