Pollen analysis of 30 modem water samples from the Shivang River, an internal river system located between the Tengger and Badain Jaran deserts, Northwest China was carried out to examine the river's capacity to c...Pollen analysis of 30 modem water samples from the Shivang River, an internal river system located between the Tengger and Badain Jaran deserts, Northwest China was carried out to examine the river's capacity to carry pollen and spores, and to assess the contribution of the water-borne pollen to pollen assemblages in lake sediments at the end of the river system. Results indicate the pollen assemblages in water samples consist of both local and upland pollen. Percentages of upland pollen reach 30% - 60%, and pollen assemblages in water samples do not indicate the nature of local vegetation at the sampling sites. Fluvial currents have the capacity to transport large quantities of pollen long distances, and the contribution of this fluvial transported pollen is relatively high, For example, percentages of Picea Dietr. pollen in water samples at sampling sites 130 km and 145 km away from Picea forests reach 16.5% and 7.7%, respectively. Fluvial pollen transport occurs primarily during flood periods, and pollen concentrations from the flood samples are 17.1 - 12.5 times those from normal fluvial flow. Reservoirs affect pollen transportation since pollen is deposited at reservoir inlets and pollen concentrations are much reduced at reservoir outlets. Human activity can thus change natural features of pollen transportation and deposition. The main factors influencing pollen concentrations and assemblages are sampling time, sampling location, and rainfall intensity.展开更多
Once,in 2007,the authors had written:regarding to the endangerment of the White-eared Night Heron (Gorsachius magnificus),it would be evidentially to say that no longer the status of the bird is to meet the Criteria E...Once,in 2007,the authors had written:regarding to the endangerment of the White-eared Night Heron (Gorsachius magnificus),it would be evidentially to say that no longer the status of the bird is to meet the Criteria EN C1 but more likely still marginally meet EN C2a(i),and hence the bird might be currently remained amongst those Endangered (EN),with caveats that,if any bird could have been found in an area outside the range of any known subpopulation,it will then warrant a lower threat status.Now,it is time for due consideration.展开更多
Based on field survey and research of Hanzhong, relocation of Nanzheng County was explored and the existing problems were analyzed. Furthermore, the re- gional characters of Nanzheng County were investigated to analyz...Based on field survey and research of Hanzhong, relocation of Nanzheng County was explored and the existing problems were analyzed. Furthermore, the re- gional characters of Nanzheng County were investigated to analyze the feasibility and necessity of relocation with lots of data and evaluation was made on relocation of Nanzheng County. In addition, the existing problems of relocation were concluded and the prospect of the county was discussed, which is of significance for relocation in Nanzheng County and even southern Shaanxi Province.展开更多
Although the concept of interval fuzzy set and its properties have been defined, its three theorems and their effectiveness are not proved. Therefore, the knowledge presentation and its operation rules of interval fuz...Although the concept of interval fuzzy set and its properties have been defined, its three theorems and their effectiveness are not proved. Therefore, the knowledge presentation and its operation rules of interval fuzzy set are studied firstly, and then the cut set of interval fuzzy set is proposed. Moreover, the decomposition theo- rem, the representation theorem and the extension theorem of interval fuzzy set are presented. Finally, examples are given to demonstrate that the classical fuzzy set is a special case of interval fuzzy set and interval fuzzy set is an effective expansion of the classical fuzzy set.展开更多
According to the survey of Guangdong mangrove resource in 2001 and authors field investigations in the past 5 years, the total mature mangrove land area of Guangdong Province was estimated at 9084 hm2, accounting for ...According to the survey of Guangdong mangrove resource in 2001 and authors field investigations in the past 5 years, the total mature mangrove land area of Guangdong Province was estimated at 9084 hm2, accounting for 41.4% of total mangrove land area of China. These mangrove forests totally consisted of 50 species belonging to 28 families, distributed at more than 100 locations along the coastlines of Guangdong and most of them present a high dense and dwarf appearance. The Ass. Avicennia marina is the most dominant mangrove association. The investigation results showed that the mangrove forests with coverage rates above 0.7 accounted for 68.0% of the total mangrove land area of the province and 77.8% of mangrove forests was less than 2 m in tree height. Since 1950, 54.6% of mangrove forests have disappeared due to paddy rice reclaim, aquaculture and city constructions. Derivational conservation efforts are still weakly empowered and should be strengthened intensively. The author suggested that mangrove laws and regulations should be enforced, mangrove scientific research should be strengthened; and mangrove conservation awareness of local community should be raised on conservation of mangroves.展开更多
This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and ch...This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.展开更多
To improve the performance of the multiple classifier system, a new method of feature-decision level fusion is proposed based on knowledge discovery. In the new method, the base classifiers operate on different featur...To improve the performance of the multiple classifier system, a new method of feature-decision level fusion is proposed based on knowledge discovery. In the new method, the base classifiers operate on different feature spaces and their types depend on different measures of between-class separability. The uncertainty measures corresponding to each output of each base classifier are induced from the established decision tables (DTs) in the form of mass function in the Dempster-Shafer theory (DST). Furthermore, an effective fusion framework is built at the feature-decision level on the basis of a generalized rough set model and the DST. The experiment for the classification of hyperspectral remote sensing images shows that the performance of the classification can be improved by the proposed method compared with that of plurality voting (PV).展开更多
AIM:To assess the long-term outcome of endoscopic hemorrhoid ligation (EHL) for the treatment of symptomatic internal hemorrhoids.METHODS:A total of 759 consecutive patients (415 males and 344 females) were enrolled.C...AIM:To assess the long-term outcome of endoscopic hemorrhoid ligation (EHL) for the treatment of symptomatic internal hemorrhoids.METHODS:A total of 759 consecutive patients (415 males and 344 females) were enrolled.Clinical presentations were rectal bleeding (593 patients) and mucosal prolapse (166 patients).All patients received EHL at outpatient clinics.Hemorrhoid severity was classified by Goligher's grading.The mean follow-up period was 55.4 mo (range,45-92 mo).RESULTS:The number of band ligations averaged 2.35 in the first session for bleeding and 2.69 for prolapsed patients.Bleeding was controlled in 587 (98.0%) patients,while prolapse was reduced in 137 (82.5%) patients.After treatment,93 patients experienced anal pain and 48 patients had mild bleeding.Patient subjective satisfaction was 93.6%.Repeat treatment or surgery was performed if symptoms were not relieved in the first session.In the bleeding group,the recurrence rate was 3.7% (22 patients) at 1 year,and 6.6%and 13.0% at 2 and 5 years.In the prolapsed group,the recurrence rate was 3.0%,9.6% and 16.9% at 1,2 and 5 years,respectively.CONCLUSION:EHL is an easy and well-tolerated procedure for the treatment of symptomatic internal hemorrhoids,with good long-term results.展开更多
Studies that compare tumor genotype with phenotype have provided the basis of a new histological/molecular classification of hepatocellular adenomas. Based on two molecular criteria (presence of a TCFI/HNF1α or β-c...Studies that compare tumor genotype with phenotype have provided the basis of a new histological/molecular classification of hepatocellular adenomas. Based on two molecular criteria (presence of a TCFI/HNF1α or β-catenin mutation), and an additional histological criterion (presence or absence of an inflammatory infiltrate), subgroups of hepatocellular adenoma can be defined and distinguished from focal nodular hyperplasia. Analysis of 96 hepatocellular adenomas performed by a French collaborative network showed that they can be divided into four broad subgroups: the first one is defined by the presence of mutations in TCF1 gene inactivating the hepatocyte nuclear factor 1 (HNF1α), the second by the presence of β-catenin activating mutations; the category without mutations of HNF1α or β-catenin is further divided into 2 subgroups depending on the presence or absence of inflammation. Therefore, the approach to the diagnosis of problematic benign hepatocytic nodules may be entering a new era directed by new molecular information. It is hoped that immunohistological tools will improve significantly diagnosis of liver biopsy in our ability to distinguish hepatocellular adenoma from focal nodular hyperplasia (FNH), and to delineate clinically meaningful entities within each group to define the best clinical management. The optimal care of patients with a liver nodule will benefit from the recent knowledge coming from molecular biology and the combined expertise of hepatologists, pathologists, radiologists, and surgeons.展开更多
A subspace-based blind Signal-to-Noise Ratio (SNR) estimation algorithm for digital bandpass signals in Additive White Gaussian Noise (AWGN) channel is discussed. The lower bounds of the mean and variance of the estim...A subspace-based blind Signal-to-Noise Ratio (SNR) estimation algorithm for digital bandpass signals in Additive White Gaussian Noise (AWGN) channel is discussed. The lower bounds of the mean and variance of the estimation are derived, and simulations are performed for the commonly used digital bandpass signals, such as MPSK (M=2, 4, 8), MFSK (M=2, 4) and MQAM (M=16, 64, 128, 256) signals. Theoretical analyses and simulation results indicate that the proposed algorithm is ef- fective even when the SNR is below 0dB. Furthermore, the algorithm can provide a blind estimator in that it needs neither the parameters of the received signals, such as the carrier frequency, symbol rate and modulation scheme, nor the synchronization of the system.展开更多
Based on a modified Lorenz system, a relatively simple four-dimensional continuous autonomous hyperchaotic system is proposed by introducing a state feedback controller. The system consists of four coupled first-order...Based on a modified Lorenz system, a relatively simple four-dimensional continuous autonomous hyperchaotic system is proposed by introducing a state feedback controller. The system consists of four coupled first-order ordinary differential equations with three nonlinear cross-product terms. Some dynamical properties of this hyperchaotic system, including equlibria, stability, Lyapunov exponent spectrum and bifurcation, are analysed in detail. Moreover, an electronic circuit diagram is designed for demonstrating the existence of the hyperchaos, and verifying computer simulation results.展开更多
Although the clinical manifestations of alcoholic liver disease are well-described, little is known about the molecular basis of liver injury. Recent studies have indicated that ethanol exposure induces global protein...Although the clinical manifestations of alcoholic liver disease are well-described, little is known about the molecular basis of liver injury. Recent studies have indicated that ethanol exposure induces global protein hyperacetylationo This reversible, post- translational modification on the E-amino groups of lysine residues has been shown to modulate multiple, diverse cellular processes ranging from transcriptional activation to microtubule stability. Thus, alcohol- induced protein hyperacetylation likely leads to major physiological consequences that contribute to alcohol-induced hepatotoxicity. Lysine acetylation is controlled by the activities of two opposing enzymes, histone acetyltransferases and histone deacetylases. Currently, efforts are aimed at determining which enzymes are responsible for the increased acetylation of specific substrates. However, the greater challenge will be to determine the physiological ramifications of protein hyperacetylation and how they might contribute to the progression of liver disease. In this review, we will first list and discuss the proteins known to be hyperacetylated in the presence of ethanol. We will then describe what is known about the mechanisms leading to increased protein acetylation and how hyperacetylation may perturb hepatic function.展开更多
The development of new taxonomical theories and approaches, particularly molecular phylogenetics, has led to the expansion of traditional morphology-based taxonomy into the concept of "integrative taxonomy."...The development of new taxonomical theories and approaches, particularly molecular phylogenetics, has led to the expansion of traditional morphology-based taxonomy into the concept of "integrative taxonomy." Taxonomic knowledge has assumed greater significance in recent years, particularly because of growing concerns over the looming biodiversity crisis. Since its establishment in 1938, the Kunming Institute of Botany(KIB), which is located in Yunnan province in Southwest China, has focused attention on the taxonomy and conservation of the flora of China. For the forthcoming 80 th anniversary of KIB, we review the achievements of researchers at KIB and their associates with respect to the taxonomy of land plants, fungi, and lichen. Major taxonomic advances are summarized for families of Calymperaceae,Cryphaeaceae, Lembophyllaceae, Neckeraceae, Polytrichaceae and Pottiaceae of mosses, Pteridaceae and Polypodiaceae of ferns, Taxaceae and Cycadaceae of gymnosperms, Asteraceae, Begoniaceae, Ericaceae,Euphorbiaceae, Gesneriaceae, Lamiaceae, Orchidaceae, Orobanchaceae, Poaceae, Theaceae and Urticaceae of angiosperms, Agaricaceae, Amanitaceae, Boletaceae, Cantharellaceae, Physalacriaceae Russulaceae, Suillaceae and Tuberaceae of fungi, and Ophioparmaceae and Parmeliaceae of lichens. Regarding the future development of taxonomy at KIB, we recommend that taxonomists continue to explore the biodiversity of China, integrate new theories and technologies with traditional taxonomic approaches,and engage in creative monographic work, with support from institutions, funding agencies, and the public.展开更多
AIM: To determine the effects of pentoxifylline (PTX) on clinical manifestations and evaluate arterial blood gas data in hepatopulmonary syndrome (HPS) in chil- dren. METHODS: In a pilot study of 10 children wit...AIM: To determine the effects of pentoxifylline (PTX) on clinical manifestations and evaluate arterial blood gas data in hepatopulmonary syndrome (HPS) in chil- dren. METHODS: In a pilot study of 10 children with chronic liver disease, who had HPS, 20 mg/kg/d PTX was ad- ministered for 3 mo. Clinical data and arterial blood gas parameters were evaluated at baseline, the end of the treatment period, and 3 mo after drug discontinuation. RESULTS: Six patients could tolerate PTX, while four patients experienced complications, Among patients who could tolerate PTX, there was a significant increase in arterial oxygen pressure (PaO2) (P = 0,02) and oxy- gen saturation (Sa02) (P = 0.04) and alveolar-arterial oxygen gradient (P = 0.02) after 3 mo of treatment. Significant decreases in Pa02 (P = 0.02) and alveolararterial oxygen gradient (P = 0.02) were also seen after drug discontinuation. CONCLUSION: PTX may improve PaO2, Sa02 and alve- olar-arterial oxygen gradient in the early stage of HPS.展开更多
Cholestasis results in a buildup of bile acids in serum and in hepatocytes.Early studies into the mechanisms of cholestatic liver injury strongly implicated bile acidinduced apoptosis as the major cause of hepatocellu...Cholestasis results in a buildup of bile acids in serum and in hepatocytes.Early studies into the mechanisms of cholestatic liver injury strongly implicated bile acidinduced apoptosis as the major cause of hepatocellular injury.Recent work has focused both on the role of bile acids in cell signaling as well as the role of sterile inflammation in the pathophysiology.Advances in modern analytical methodology have allowed for more accurate measuring of bile acid concentrations in serum,liver,and bile to very low levels of detection.Interestingly,toxic bile acid levels are seemingly far lower than previously hypothesized.The initial hypothesis has been based largely upon the exposure of μmol/L concentrations of toxic bile acids and bile salts to primary hepatocytes in cell culture,the possibility that in vivo bile acid concentrations may be far lower than the observed in vitro toxicity has far reaching implications in the mechanism of injury.This review will focus on both how different bile acids and different bile acid concentrations can affect hepatocytes during cholestasis,and additionally provide insight into how these data support recent hypotheses that cholestatic liver injury may not occur through direct bile acid-induced apoptosis,but may involve largely inflammatory cell-mediated liver cell necrosis.展开更多
In order to provide references for selecting highly efficient red mud flocculants, the behaviour of polyacrylamidomethyltrimethyl ammonium chloride (PATAC) in red mud separation process was investigated. PATAC was e...In order to provide references for selecting highly efficient red mud flocculants, the behaviour of polyacrylamidomethyltrimethyl ammonium chloride (PATAC) in red mud separation process was investigated. PATAC was employed as a flocculant for red mud separation from the caustic aluminate liquor at 95 ℃. The used red mud was generated from Chinese diaspore bauxite in Bayer process of alumina production. And the changes of PATAC before or after being treated in caustic solution at 95 ℃ were studied by thermogravimetry (TG) and Fourier transform infrared (FTIR) spectral analysis. The results show that PATAC fails in effectively focculating red mud and PATAC is readily converted to a quaternary ammonium hydroxide (PATAH) in caustic solution. PATAH can be decomposed to a new polymer (HPATAH) even at 95 ℃. Furthermore, there is an intramolecular hydrogen bond formed in the HPATAH polymer chain with two functional groups of--CH2--OH and --CONH2. Therefore, the poor flocculation property of PATAC for red mud separation can be attributed to the thermal decomposition of PATAC in the caustic red mud slurry at 95 ℃ and the formation of intramolecular hydrogen bond in the polymer chain of HPATAH during the thermal decomposition, which causes the absorbable functional groups of PATAC to decrease greatly.展开更多
文摘Pollen analysis of 30 modem water samples from the Shivang River, an internal river system located between the Tengger and Badain Jaran deserts, Northwest China was carried out to examine the river's capacity to carry pollen and spores, and to assess the contribution of the water-borne pollen to pollen assemblages in lake sediments at the end of the river system. Results indicate the pollen assemblages in water samples consist of both local and upland pollen. Percentages of upland pollen reach 30% - 60%, and pollen assemblages in water samples do not indicate the nature of local vegetation at the sampling sites. Fluvial currents have the capacity to transport large quantities of pollen long distances, and the contribution of this fluvial transported pollen is relatively high, For example, percentages of Picea Dietr. pollen in water samples at sampling sites 130 km and 145 km away from Picea forests reach 16.5% and 7.7%, respectively. Fluvial pollen transport occurs primarily during flood periods, and pollen concentrations from the flood samples are 17.1 - 12.5 times those from normal fluvial flow. Reservoirs affect pollen transportation since pollen is deposited at reservoir inlets and pollen concentrations are much reduced at reservoir outlets. Human activity can thus change natural features of pollen transportation and deposition. The main factors influencing pollen concentrations and assemblages are sampling time, sampling location, and rainfall intensity.
基金Zoologische Gesellschaft für Arten und Populationsschutz e. V. (ZGAP) in Germanythe Royal Society for the Protection of Birds (RSPB) in the United Kingdom
文摘Once,in 2007,the authors had written:regarding to the endangerment of the White-eared Night Heron (Gorsachius magnificus),it would be evidentially to say that no longer the status of the bird is to meet the Criteria EN C1 but more likely still marginally meet EN C2a(i),and hence the bird might be currently remained amongst those Endangered (EN),with caveats that,if any bird could have been found in an area outside the range of any known subpopulation,it will then warrant a lower threat status.Now,it is time for due consideration.
基金Supported by the Fundamental Research Funds for the Central Universities(GK261002145)Key Teaching Reform Research of Shaanxi Normal University in 2014(14JG07)Teacher Education Program of Shaanxi Normal University in 2014(JSJY2014J014)~~
文摘Based on field survey and research of Hanzhong, relocation of Nanzheng County was explored and the existing problems were analyzed. Furthermore, the re- gional characters of Nanzheng County were investigated to analyze the feasibility and necessity of relocation with lots of data and evaluation was made on relocation of Nanzheng County. In addition, the existing problems of relocation were concluded and the prospect of the county was discussed, which is of significance for relocation in Nanzheng County and even southern Shaanxi Province.
基金Supported by the Aeronautical Science Foundation(20115868009)the Open Project Program of Key Laboratory of Intelligent Computing&Information Processing of Ministry of Education in Xiangtan University(2011ICIP04)+1 种基金the Program of 211 Innovation Engineering on Information in Xiamen University(2009-2011)the College Students Innovation Training Plan of Xianmen University~~
文摘Although the concept of interval fuzzy set and its properties have been defined, its three theorems and their effectiveness are not proved. Therefore, the knowledge presentation and its operation rules of interval fuzzy set are studied firstly, and then the cut set of interval fuzzy set is proposed. Moreover, the decomposition theo- rem, the representation theorem and the extension theorem of interval fuzzy set are presented. Finally, examples are given to demonstrate that the classical fuzzy set is a special case of interval fuzzy set and interval fuzzy set is an effective expansion of the classical fuzzy set.
文摘According to the survey of Guangdong mangrove resource in 2001 and authors field investigations in the past 5 years, the total mature mangrove land area of Guangdong Province was estimated at 9084 hm2, accounting for 41.4% of total mangrove land area of China. These mangrove forests totally consisted of 50 species belonging to 28 families, distributed at more than 100 locations along the coastlines of Guangdong and most of them present a high dense and dwarf appearance. The Ass. Avicennia marina is the most dominant mangrove association. The investigation results showed that the mangrove forests with coverage rates above 0.7 accounted for 68.0% of the total mangrove land area of the province and 77.8% of mangrove forests was less than 2 m in tree height. Since 1950, 54.6% of mangrove forests have disappeared due to paddy rice reclaim, aquaculture and city constructions. Derivational conservation efforts are still weakly empowered and should be strengthened intensively. The author suggested that mangrove laws and regulations should be enforced, mangrove scientific research should be strengthened; and mangrove conservation awareness of local community should be raised on conservation of mangroves.
文摘This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.
文摘To improve the performance of the multiple classifier system, a new method of feature-decision level fusion is proposed based on knowledge discovery. In the new method, the base classifiers operate on different feature spaces and their types depend on different measures of between-class separability. The uncertainty measures corresponding to each output of each base classifier are induced from the established decision tables (DTs) in the form of mass function in the Dempster-Shafer theory (DST). Furthermore, an effective fusion framework is built at the feature-decision level on the basis of a generalized rough set model and the DST. The experiment for the classification of hyperspectral remote sensing images shows that the performance of the classification can be improved by the proposed method compared with that of plurality voting (PV).
文摘AIM:To assess the long-term outcome of endoscopic hemorrhoid ligation (EHL) for the treatment of symptomatic internal hemorrhoids.METHODS:A total of 759 consecutive patients (415 males and 344 females) were enrolled.Clinical presentations were rectal bleeding (593 patients) and mucosal prolapse (166 patients).All patients received EHL at outpatient clinics.Hemorrhoid severity was classified by Goligher's grading.The mean follow-up period was 55.4 mo (range,45-92 mo).RESULTS:The number of band ligations averaged 2.35 in the first session for bleeding and 2.69 for prolapsed patients.Bleeding was controlled in 587 (98.0%) patients,while prolapse was reduced in 137 (82.5%) patients.After treatment,93 patients experienced anal pain and 48 patients had mild bleeding.Patient subjective satisfaction was 93.6%.Repeat treatment or surgery was performed if symptoms were not relieved in the first session.In the bleeding group,the recurrence rate was 3.7% (22 patients) at 1 year,and 6.6%and 13.0% at 2 and 5 years.In the prolapsed group,the recurrence rate was 3.0%,9.6% and 16.9% at 1,2 and 5 years,respectively.CONCLUSION:EHL is an easy and well-tolerated procedure for the treatment of symptomatic internal hemorrhoids,with good long-term results.
文摘Studies that compare tumor genotype with phenotype have provided the basis of a new histological/molecular classification of hepatocellular adenomas. Based on two molecular criteria (presence of a TCFI/HNF1α or β-catenin mutation), and an additional histological criterion (presence or absence of an inflammatory infiltrate), subgroups of hepatocellular adenoma can be defined and distinguished from focal nodular hyperplasia. Analysis of 96 hepatocellular adenomas performed by a French collaborative network showed that they can be divided into four broad subgroups: the first one is defined by the presence of mutations in TCF1 gene inactivating the hepatocyte nuclear factor 1 (HNF1α), the second by the presence of β-catenin activating mutations; the category without mutations of HNF1α or β-catenin is further divided into 2 subgroups depending on the presence or absence of inflammation. Therefore, the approach to the diagnosis of problematic benign hepatocytic nodules may be entering a new era directed by new molecular information. It is hoped that immunohistological tools will improve significantly diagnosis of liver biopsy in our ability to distinguish hepatocellular adenoma from focal nodular hyperplasia (FNH), and to delineate clinically meaningful entities within each group to define the best clinical management. The optimal care of patients with a liver nodule will benefit from the recent knowledge coming from molecular biology and the combined expertise of hepatologists, pathologists, radiologists, and surgeons.
文摘A subspace-based blind Signal-to-Noise Ratio (SNR) estimation algorithm for digital bandpass signals in Additive White Gaussian Noise (AWGN) channel is discussed. The lower bounds of the mean and variance of the estimation are derived, and simulations are performed for the commonly used digital bandpass signals, such as MPSK (M=2, 4, 8), MFSK (M=2, 4) and MQAM (M=16, 64, 128, 256) signals. Theoretical analyses and simulation results indicate that the proposed algorithm is ef- fective even when the SNR is below 0dB. Furthermore, the algorithm can provide a blind estimator in that it needs neither the parameters of the received signals, such as the carrier frequency, symbol rate and modulation scheme, nor the synchronization of the system.
基金Project supported by the Natural Science Foundation of Zhejiang Province, China (Grant No Y105175) and the Science investigation Foundation of Hangzhou Dianzi University, China (Grant No KYS051505010).
文摘Based on a modified Lorenz system, a relatively simple four-dimensional continuous autonomous hyperchaotic system is proposed by introducing a state feedback controller. The system consists of four coupled first-order ordinary differential equations with three nonlinear cross-product terms. Some dynamical properties of this hyperchaotic system, including equlibria, stability, Lyapunov exponent spectrum and bifurcation, are analysed in detail. Moreover, an electronic circuit diagram is designed for demonstrating the existence of the hyperchaos, and verifying computer simulation results.
基金Supported by The National Institute of Alcohol Abuse and Alcoholism (R21 AA015683) awarded to P.L.T.
文摘Although the clinical manifestations of alcoholic liver disease are well-described, little is known about the molecular basis of liver injury. Recent studies have indicated that ethanol exposure induces global protein hyperacetylationo This reversible, post- translational modification on the E-amino groups of lysine residues has been shown to modulate multiple, diverse cellular processes ranging from transcriptional activation to microtubule stability. Thus, alcohol- induced protein hyperacetylation likely leads to major physiological consequences that contribute to alcohol-induced hepatotoxicity. Lysine acetylation is controlled by the activities of two opposing enzymes, histone acetyltransferases and histone deacetylases. Currently, efforts are aimed at determining which enzymes are responsible for the increased acetylation of specific substrates. However, the greater challenge will be to determine the physiological ramifications of protein hyperacetylation and how they might contribute to the progression of liver disease. In this review, we will first list and discuss the proteins known to be hyperacetylated in the presence of ethanol. We will then describe what is known about the mechanisms leading to increased protein acetylation and how hyperacetylation may perturb hepatic function.
基金supported by the National Natural Science Foundation of China (No. 31700182)
文摘The development of new taxonomical theories and approaches, particularly molecular phylogenetics, has led to the expansion of traditional morphology-based taxonomy into the concept of "integrative taxonomy." Taxonomic knowledge has assumed greater significance in recent years, particularly because of growing concerns over the looming biodiversity crisis. Since its establishment in 1938, the Kunming Institute of Botany(KIB), which is located in Yunnan province in Southwest China, has focused attention on the taxonomy and conservation of the flora of China. For the forthcoming 80 th anniversary of KIB, we review the achievements of researchers at KIB and their associates with respect to the taxonomy of land plants, fungi, and lichen. Major taxonomic advances are summarized for families of Calymperaceae,Cryphaeaceae, Lembophyllaceae, Neckeraceae, Polytrichaceae and Pottiaceae of mosses, Pteridaceae and Polypodiaceae of ferns, Taxaceae and Cycadaceae of gymnosperms, Asteraceae, Begoniaceae, Ericaceae,Euphorbiaceae, Gesneriaceae, Lamiaceae, Orchidaceae, Orobanchaceae, Poaceae, Theaceae and Urticaceae of angiosperms, Agaricaceae, Amanitaceae, Boletaceae, Cantharellaceae, Physalacriaceae Russulaceae, Suillaceae and Tuberaceae of fungi, and Ophioparmaceae and Parmeliaceae of lichens. Regarding the future development of taxonomy at KIB, we recommend that taxonomists continue to explore the biodiversity of China, integrate new theories and technologies with traditional taxonomic approaches,and engage in creative monographic work, with support from institutions, funding agencies, and the public.
基金Supported by Research Council of Mashhad University of Medical Sciences
文摘AIM: To determine the effects of pentoxifylline (PTX) on clinical manifestations and evaluate arterial blood gas data in hepatopulmonary syndrome (HPS) in chil- dren. METHODS: In a pilot study of 10 children with chronic liver disease, who had HPS, 20 mg/kg/d PTX was ad- ministered for 3 mo. Clinical data and arterial blood gas parameters were evaluated at baseline, the end of the treatment period, and 3 mo after drug discontinuation. RESULTS: Six patients could tolerate PTX, while four patients experienced complications, Among patients who could tolerate PTX, there was a significant increase in arterial oxygen pressure (PaO2) (P = 0,02) and oxy- gen saturation (Sa02) (P = 0.04) and alveolar-arterial oxygen gradient (P = 0.02) after 3 mo of treatment. Significant decreases in Pa02 (P = 0.02) and alveolararterial oxygen gradient (P = 0.02) were also seen after drug discontinuation. CONCLUSION: PTX may improve PaO2, Sa02 and alve- olar-arterial oxygen gradient in the early stage of HPS.
基金Supported by The National Institutes of Health grants,R01 DK070195 and R01 AA12916,to Jaeschke Hthe "Training Program in Environmental Toxicology",T32 ES007079-26A2 from the National Institute of Environmental Health Sciences
文摘Cholestasis results in a buildup of bile acids in serum and in hepatocytes.Early studies into the mechanisms of cholestatic liver injury strongly implicated bile acidinduced apoptosis as the major cause of hepatocellular injury.Recent work has focused both on the role of bile acids in cell signaling as well as the role of sterile inflammation in the pathophysiology.Advances in modern analytical methodology have allowed for more accurate measuring of bile acid concentrations in serum,liver,and bile to very low levels of detection.Interestingly,toxic bile acid levels are seemingly far lower than previously hypothesized.The initial hypothesis has been based largely upon the exposure of μmol/L concentrations of toxic bile acids and bile salts to primary hepatocytes in cell culture,the possibility that in vivo bile acid concentrations may be far lower than the observed in vitro toxicity has far reaching implications in the mechanism of injury.This review will focus on both how different bile acids and different bile acid concentrations can affect hepatocytes during cholestasis,and additionally provide insight into how these data support recent hypotheses that cholestatic liver injury may not occur through direct bile acid-induced apoptosis,but may involve largely inflammatory cell-mediated liver cell necrosis.
基金Project(2005CB623702) supported by the Major State Basic Research and Development Program of China
文摘In order to provide references for selecting highly efficient red mud flocculants, the behaviour of polyacrylamidomethyltrimethyl ammonium chloride (PATAC) in red mud separation process was investigated. PATAC was employed as a flocculant for red mud separation from the caustic aluminate liquor at 95 ℃. The used red mud was generated from Chinese diaspore bauxite in Bayer process of alumina production. And the changes of PATAC before or after being treated in caustic solution at 95 ℃ were studied by thermogravimetry (TG) and Fourier transform infrared (FTIR) spectral analysis. The results show that PATAC fails in effectively focculating red mud and PATAC is readily converted to a quaternary ammonium hydroxide (PATAH) in caustic solution. PATAH can be decomposed to a new polymer (HPATAH) even at 95 ℃. Furthermore, there is an intramolecular hydrogen bond formed in the HPATAH polymer chain with two functional groups of--CH2--OH and --CONH2. Therefore, the poor flocculation property of PATAC for red mud separation can be attributed to the thermal decomposition of PATAC in the caustic red mud slurry at 95 ℃ and the formation of intramolecular hydrogen bond in the polymer chain of HPATAH during the thermal decomposition, which causes the absorbable functional groups of PATAC to decrease greatly.