This report describes the second known case of disseminated coccidioidomycosis mimicking mycosis fungoides since the original description more than 100 years ago. Coccidioidomycosis should be considered in persons fro...This report describes the second known case of disseminated coccidioidomycosis mimicking mycosis fungoides since the original description more than 100 years ago. Coccidioidomycosis should be considered in persons from an endemic area presenting with nonhealing or suspicious skin lesions. Diagnosis is established by skin biopsy and silver staining showing granulomas and classic Coccidioides immitis spherules. Disseminated coccidioidomycosis most commonly involves the skin and can have a variety of cutaneous manifestations. The first description of a Coccidioides immitis infection in 1892 was initially diagnosed as mycosis fungoides. We present the second case of coccidioidomycosis masquerading as mycosis展开更多
Background: Sweet syndrome (acute febrile neutrophilic dermatosis)may arise in association with a variety of underlying systemic diseases. Only 1 case of coccidioidomycosis associated Sweet syndrome has previously bee...Background: Sweet syndrome (acute febrile neutrophilic dermatosis)may arise in association with a variety of underlying systemic diseases. Only 1 case of coccidioidomycosis associated Sweet syndrome has previously been reported.Observations: We describe 2 patients who developed Sweet syndrome during the onset of acute pulmonary coccidioidomycosis.Systemic antifungal therapy was given in bothcases. Respiratory symptoms and skin lesions resolved within 5 weeks. Conclusions: Sweet syndrome may be a presenting feature of coccidioidomycosis. Recognition of the underlying pulmonary infection is important so that inappropriate treatmentwith systemic corticosteroids can be avoided.展开更多
文摘This report describes the second known case of disseminated coccidioidomycosis mimicking mycosis fungoides since the original description more than 100 years ago. Coccidioidomycosis should be considered in persons from an endemic area presenting with nonhealing or suspicious skin lesions. Diagnosis is established by skin biopsy and silver staining showing granulomas and classic Coccidioides immitis spherules. Disseminated coccidioidomycosis most commonly involves the skin and can have a variety of cutaneous manifestations. The first description of a Coccidioides immitis infection in 1892 was initially diagnosed as mycosis fungoides. We present the second case of coccidioidomycosis masquerading as mycosis
文摘Background: Sweet syndrome (acute febrile neutrophilic dermatosis)may arise in association with a variety of underlying systemic diseases. Only 1 case of coccidioidomycosis associated Sweet syndrome has previously been reported.Observations: We describe 2 patients who developed Sweet syndrome during the onset of acute pulmonary coccidioidomycosis.Systemic antifungal therapy was given in bothcases. Respiratory symptoms and skin lesions resolved within 5 weeks. Conclusions: Sweet syndrome may be a presenting feature of coccidioidomycosis. Recognition of the underlying pulmonary infection is important so that inappropriate treatmentwith systemic corticosteroids can be avoided.
