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理冲颗粒对子宫肌瘤小鼠性激素水平及子宫平滑肌的影响
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作者 侯秋苑 李大炜 +2 位作者 陈文健 陆少君 祁银德 《食品与药品》 CAS 2024年第2期138-143,共6页
目的探讨理冲颗粒对子宫肌瘤小鼠性素水平和子宫平滑肌、子宫、卵巢重量及系数的影响。方法通过肌注苯甲酸雌二醇,建立小鼠子宫肌瘤模型。72只ICR雌性小鼠随机分为6组:空白组、模型组、理冲颗粒3个剂量(7.5,15,30 g/kg)组、桂枝茯苓胶囊... 目的探讨理冲颗粒对子宫肌瘤小鼠性素水平和子宫平滑肌、子宫、卵巢重量及系数的影响。方法通过肌注苯甲酸雌二醇,建立小鼠子宫肌瘤模型。72只ICR雌性小鼠随机分为6组:空白组、模型组、理冲颗粒3个剂量(7.5,15,30 g/kg)组、桂枝茯苓胶囊组(剂量为0.47 g/kg),连续15 d灌胃给药。末次给药24 h后,心脏取血观察各组小鼠的血清性激素水平,取血后处死小鼠,解剖,称重,测量子宫分角下最大的竖径、横径,计算脏器系数,进行病理组织学检查。结果理冲颗粒3个剂量均能显著降低子宫肌瘤小鼠子宫重量、子宫脏器系数、血清中雌二醇、孕激素、黄体生成素及雌激素受体水平(P<0.05);理冲颗粒中、高剂量能显著降低子宫肌瘤小鼠血清中孕激素受体水平(P<0.05),理冲颗粒高剂量能显著降低子宫肌瘤小鼠血清中的促卵泡激素水平(P<0.05);理冲颗粒3个剂量均能不同程度地改善子宫肌瘤小鼠子宫的病理组织形态。结论理冲颗粒对子宫肌瘤模型小鼠具有一定的治疗作用。 展开更多
关键词 理冲颗粒 子宫肌瘤 子宫平滑肌 性激素
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理冲颗粒的薄层鉴别方法的建立
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作者 侯秋苑 李惠敏 +3 位作者 林凤屏 冯白茹 殷蕾 梁可 《江西化工》 2022年第6期41-44,共4页
文章研究目的为建立理冲颗粒的薄层鉴别方法,研究方法为以黄芪甲苷为对照品、三棱为对照药材,对理冲颗粒进行薄层鉴别,并考察了不同薄层材料、温度及湿度对理冲颗粒薄层鉴别的影响。结果表明,以黄芪甲苷为对照品,三氯甲烷-甲醇-水(15:7... 文章研究目的为建立理冲颗粒的薄层鉴别方法,研究方法为以黄芪甲苷为对照品、三棱为对照药材,对理冲颗粒进行薄层鉴别,并考察了不同薄层材料、温度及湿度对理冲颗粒薄层鉴别的影响。结果表明,以黄芪甲苷为对照品,三氯甲烷-甲醇-水(15:7:2)为展开系统,10%硫酸乙醇为显色剂;以三棱为对照药材,石油醚(60~90℃)-乙酸乙酯(4:1)为展开系统,5μL点样量点于硅胶G薄层板时,所得的薄层色谱斑点清晰,分离度好,专属性强。该鉴别方法操作简便,重复性好,可作为理冲颗粒的薄层鉴别方法。 展开更多
关键词 理冲颗粒 黄芪甲苷 三棱 薄层鉴别
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The hydro-abrasive erosion wear behavior of duplex-treated surfaces of AISI H13 tool steel
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作者 TUTAR Mumin AYDIN Hakan +2 位作者 DURMUS Ali BAYRAM Ali YIGIT Kurtulus 《Science China(Technological Sciences)》 SCIE EI CAS 2014年第5期1040-1051,共12页
The influence of duplex surface treatments consisting of a DC-pulsed plasma nitriding process and subsequent coatings of CrN and TiAlN deposited by physical vapor deposition(PVD)on AISI H13 tool steel was studied in t... The influence of duplex surface treatments consisting of a DC-pulsed plasma nitriding process and subsequent coatings of CrN and TiAlN deposited by physical vapor deposition(PVD)on AISI H13 tool steel was studied in this article.The treated samples were characterized using metallographic techniques,SEM,EDS,and microhardness methods.Hydro-abrasive erosion wear tests were performed in a specifically designed wear tester in which the samples were rotated in a wear tank containing a mixture of distilled water and ceramic abrasive chips with a fixed rotational speed.The wear rates caused by the abrasive particle impacts were assessed based on accumulated weight loss measurements.The worn surfaces were also characterized using optical microscopy,SEM,and EDS.Microhardness measurements indicated a significant increase in the surface hardness of the duplex-treated samples.The surfaces of the samples with the TiAlN coating were approximately 15 times harder than that of the untreated samples and 3 times that of the plasma nitrided samples.Hydro-abrasive erosion wear results showed that the duplex surface treatments,especially the CrN coating,displayed the highest erosion wear resistance. 展开更多
关键词 plasma nitriding physical vapor deposition duplex surface treatment MICROHARDNESS hydro-abrasive erosion wear
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