Based on the data about sedimentary facies and palaeogeography, this paper proves the existence of the Cathaysia (the part in eastern Zhejiang and northern Fujian, the same hereinafter) and makes a survey about its pa...Based on the data about sedimentary facies and palaeogeography, this paper proves the existence of the Cathaysia (the part in eastern Zhejiang and northern Fujian, the same hereinafter) and makes a survey about its palaeogeography since Sinian Period. It also discusses the evolution of the tectonic environment of this region during Phanerozoic Eon, according to the features such as the composition of sandstones derived from the old land and alkalinity of volcanic rocks and so on. Continuous uplifting was maintained in Cathaysia during Sinian Period and Paleozoic Era, typically with no significant tectono-magmatic activity being observed. Its northwestern margin belongs to the type of passive continental margin during the middle and late phase of Caledonian Cycle. It showed the characteristics of a steady continent in late Paleozoic era, but was turned quickly into an active continental margin after the middle Jurassic period.展开更多
This paper first explores the concepts of values and ethics, utilizing a social work framework. It proceeds to examine various dilemmas involved in communicating with others via social media tools. Historic boundary i...This paper first explores the concepts of values and ethics, utilizing a social work framework. It proceeds to examine various dilemmas involved in communicating with others via social media tools. Historic boundary issues between students and faculty are discussed, as well as emerging dilemmas that are becoming prevalent within electronic communicative networks （e.g., Skype, Facebook, Myspace, Linkedln, Twitter, and Texting）. The need for policy guidelines within academic environments in the use of social media is emphasized, Similar to the National Association of Social Workers （NASW） Code of Ethics, Arizona State University （ASU） is cited as a model in providing some structure regarding staff responsibility and unethical conduct within its academic setting. An enhancement of these guidelines to include electronic communication is recommended. Guidance is necessary to promote responsible communication, as the right to privacy, freedom of speech, and anonymity are all illusions of invulnerability.展开更多
Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perfo...Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perform such a variety of functions has become much more intensive because the value of the genomic sequences relies on the accuracy of understanding the encoded gene products. Although the static three-dimensional structures of many proteins are known, the functions of proteins are ulti- mately governed by their dynamic characteristics, including the folding process, conformational fluctuations, molecular mo- tions, and protein-ligand interactions. In this review, the physicochemical principles underlying these dynamic processes are discussed in depth based on the free energy landscape （FEL） theory. Questions of why and how proteins fold into their native conformational states, why proteins are inherently dynamic, and how their dynamic personalities govern protein functions are answered. This paper will contribute to the understanding of structure-function relationship of proteins in the post-genome era of life science research.展开更多
文摘Based on the data about sedimentary facies and palaeogeography, this paper proves the existence of the Cathaysia (the part in eastern Zhejiang and northern Fujian, the same hereinafter) and makes a survey about its palaeogeography since Sinian Period. It also discusses the evolution of the tectonic environment of this region during Phanerozoic Eon, according to the features such as the composition of sandstones derived from the old land and alkalinity of volcanic rocks and so on. Continuous uplifting was maintained in Cathaysia during Sinian Period and Paleozoic Era, typically with no significant tectono-magmatic activity being observed. Its northwestern margin belongs to the type of passive continental margin during the middle and late phase of Caledonian Cycle. It showed the characteristics of a steady continent in late Paleozoic era, but was turned quickly into an active continental margin after the middle Jurassic period.
文摘This paper first explores the concepts of values and ethics, utilizing a social work framework. It proceeds to examine various dilemmas involved in communicating with others via social media tools. Historic boundary issues between students and faculty are discussed, as well as emerging dilemmas that are becoming prevalent within electronic communicative networks （e.g., Skype, Facebook, Myspace, Linkedln, Twitter, and Texting）. The need for policy guidelines within academic environments in the use of social media is emphasized, Similar to the National Association of Social Workers （NASW） Code of Ethics, Arizona State University （ASU） is cited as a model in providing some structure regarding staff responsibility and unethical conduct within its academic setting. An enhancement of these guidelines to include electronic communication is recommended. Guidance is necessary to promote responsible communication, as the right to privacy, freedom of speech, and anonymity are all illusions of invulnerability.
基金supported by the National Natural Science Foundation of China(31370715,31160181,31360277,30860011)the National Basic Research Program of China(2013CB127500)+1 种基金the Program of Innovation Group of Yunnan Province(2011CI123)Foundation for Key Teacher in Yunnan University(XT412003)
文摘Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perform such a variety of functions has become much more intensive because the value of the genomic sequences relies on the accuracy of understanding the encoded gene products. Although the static three-dimensional structures of many proteins are known, the functions of proteins are ulti- mately governed by their dynamic characteristics, including the folding process, conformational fluctuations, molecular mo- tions, and protein-ligand interactions. In this review, the physicochemical principles underlying these dynamic processes are discussed in depth based on the free energy landscape （FEL） theory. Questions of why and how proteins fold into their native conformational states, why proteins are inherently dynamic, and how their dynamic personalities govern protein functions are answered. This paper will contribute to the understanding of structure-function relationship of proteins in the post-genome era of life science research.
