AIM： To investigate whether the degree of rectal distension could define the rectum functions as a conduit METHODS： Response of the rectal and anal pressure to 2 types of rectal balloon distension, rapid voluminous ...AIM： To investigate whether the degree of rectal distension could define the rectum functions as a conduit METHODS： Response of the rectal and anal pressure to 2 types of rectal balloon distension, rapid voluminous and slow gradual distention, was recorded in 21 healthy volunteers （12 men, 9 women, age 41.7 ± 10.6 years）. The test was repeated with sphincteric squeeze on urgent sensation. RESULTS： Rapid voluminous rectal distension resulted in a significant rectal pressure increase （P 〈 0.001）, an anal pressure decline （P 〈 0.05） and balloon expulsion. The subjects felt urgent sensation but did not feel the 1^st rectal sensation. On urgent sensation, anal squeeze caused a significant rectal pressure decrease （P 〈 0.001） and urgency disappearance. Slow incremental rectal filling drew a rectometrogram with a ＂tone＂ limb representing a gradual rectal pressure increase during rectal filling, and an ＂evacuation limb＂ representing a sharp pressure increase during balloon expulsion. The curve recorded both the ist rectal sensation and the urgent sensation. CONCLUSION： The rectum has apparently two functions： transportation （conduit） and storage, both depending on the degree of rectal filling. If the fecal material received by the rectum is small, it is stored in the rectum until a big volume is reached that can affect a degree of rectal distension sufficient to initiate the defecation reflex. Large volume rectal distension evokes directly the rectoanal inhibitory reflex with a resulting defecation.展开更多
Recent evidence has highlighted the impact of glycemic control on the incidence and progression of diabetic micro- and macrovascular complications, and on cardiovascular risk in the non-diabetic population. Postprandi...Recent evidence has highlighted the impact of glycemic control on the incidence and progression of diabetic micro- and macrovascular complications, and on cardiovascular risk in the non-diabetic population. Postprandial blood glucose concentrations make a major contribution to overall glycemic control, and are determined in part by upper gastrointestinal function. Conversely, poor glycemic control has an acute, reversible effect on gastrointestinal motility. Insights into the mechanisms by which the gut contributes to glycemia have given rise to a number of novel dietary and pharmacological strategies designed to lower postprandial blood glucose concentrations.展开更多
Internal hemiation of the small bowel is a relatively rare cause of intestinal obstruction. Left paraduodenal hernia resulting from abnormal rotation of the midgut during embryonic development is the most common form ...Internal hemiation of the small bowel is a relatively rare cause of intestinal obstruction. Left paraduodenal hernia resulting from abnormal rotation of the midgut during embryonic development is the most common form of congenital internal hernia. We report our experience in the diagnosis and management of a young male with left paraduodenal hernia presenting as recurrent intestinal obstruction. Correct preoperative diagnosis of left paraduodenal hernia had been difficult due to non-specific clinical presentations, but the advent of modern imaging technology makes early and correct diagnosis possible, Due to the risk of obstruction and strangulation, surgical treatment is indicated; however, timely intervention increases the likelihood of a favorable outcome.展开更多
Since Lenger＇s detection of magnetic photons in homeopathic remedies by magnetic resonance the mystery of homeopathy comes to a solution. Homeopathy is a regulation therapy curing hypo- and hyper-functions of patholo...Since Lenger＇s detection of magnetic photons in homeopathic remedies by magnetic resonance the mystery of homeopathy comes to a solution. Homeopathy is a regulation therapy curing hypo- and hyper-functions of pathological pathways. It reacts according to the principle of resonance. The fundamental principles of homeopathy as proving, symptom picture, curing according to the Law of Similars and the production of homeopathic remedies over the Avogadro number by repeated dilution and succussion are explained to have the same frequencies so that the resonance principle can work. Pathological pathways are cured by using their highly potentized substrates, inhibitors and enzymes, given daily or each second day. This is in contradiction to the normal applied homeopathy. The efficacy of homeopathy now has a scientific base and is completely explained by applying biochemical and biophysical laws.展开更多
文摘AIM： To investigate whether the degree of rectal distension could define the rectum functions as a conduit METHODS： Response of the rectal and anal pressure to 2 types of rectal balloon distension, rapid voluminous and slow gradual distention, was recorded in 21 healthy volunteers （12 men, 9 women, age 41.7 ± 10.6 years）. The test was repeated with sphincteric squeeze on urgent sensation. RESULTS： Rapid voluminous rectal distension resulted in a significant rectal pressure increase （P 〈 0.001）, an anal pressure decline （P 〈 0.05） and balloon expulsion. The subjects felt urgent sensation but did not feel the 1^st rectal sensation. On urgent sensation, anal squeeze caused a significant rectal pressure decrease （P 〈 0.001） and urgency disappearance. Slow incremental rectal filling drew a rectometrogram with a ＂tone＂ limb representing a gradual rectal pressure increase during rectal filling, and an ＂evacuation limb＂ representing a sharp pressure increase during balloon expulsion. The curve recorded both the ist rectal sensation and the urgent sensation. CONCLUSION： The rectum has apparently two functions： transportation （conduit） and storage, both depending on the degree of rectal filling. If the fecal material received by the rectum is small, it is stored in the rectum until a big volume is reached that can affect a degree of rectal distension sufficient to initiate the defecation reflex. Large volume rectal distension evokes directly the rectoanal inhibitory reflex with a resulting defecation.
文摘Recent evidence has highlighted the impact of glycemic control on the incidence and progression of diabetic micro- and macrovascular complications, and on cardiovascular risk in the non-diabetic population. Postprandial blood glucose concentrations make a major contribution to overall glycemic control, and are determined in part by upper gastrointestinal function. Conversely, poor glycemic control has an acute, reversible effect on gastrointestinal motility. Insights into the mechanisms by which the gut contributes to glycemia have given rise to a number of novel dietary and pharmacological strategies designed to lower postprandial blood glucose concentrations.
文摘Internal hemiation of the small bowel is a relatively rare cause of intestinal obstruction. Left paraduodenal hernia resulting from abnormal rotation of the midgut during embryonic development is the most common form of congenital internal hernia. We report our experience in the diagnosis and management of a young male with left paraduodenal hernia presenting as recurrent intestinal obstruction. Correct preoperative diagnosis of left paraduodenal hernia had been difficult due to non-specific clinical presentations, but the advent of modern imaging technology makes early and correct diagnosis possible, Due to the risk of obstruction and strangulation, surgical treatment is indicated; however, timely intervention increases the likelihood of a favorable outcome.
文摘Since Lenger＇s detection of magnetic photons in homeopathic remedies by magnetic resonance the mystery of homeopathy comes to a solution. Homeopathy is a regulation therapy curing hypo- and hyper-functions of pathological pathways. It reacts according to the principle of resonance. The fundamental principles of homeopathy as proving, symptom picture, curing according to the Law of Similars and the production of homeopathic remedies over the Avogadro number by repeated dilution and succussion are explained to have the same frequencies so that the resonance principle can work. Pathological pathways are cured by using their highly potentized substrates, inhibitors and enzymes, given daily or each second day. This is in contradiction to the normal applied homeopathy. The efficacy of homeopathy now has a scientific base and is completely explained by applying biochemical and biophysical laws.
