This paper discussed a method to judge and to reject the mistake and error of the monitoring strategies for English teaching and learning, and alsopresented a classification of mistake and error according to the follo...This paper discussed a method to judge and to reject the mistake and error of the monitoring strategies for English teaching and learning, and alsopresented a classification of mistake and error according to the following factors： the definition and analysisofmistake and error.With the development of theanalysis theories, more attention has been paid to the characteristic and the principle of mistake and error in the second language teaching and learning. By analyzing the differences between mistake and error, the teachers and learners can get clear of the study of English and improve the ability of using English.展开更多
Intemship positions are non-commissioned officers serving students with the knowledge and skills learned in school is based, went to a professional army posts counterparts learning and training, in practice, further t...Intemship positions are non-commissioned officers serving students with the knowledge and skills learned in school is based, went to a professional army posts counterparts learning and training, in practice, further temper professional skills, familiar with the work force characteristics, to achieve after graduation ＂Zero posts＂ lay a solid foundation, Competency-based education （Competence Based Education, referred CBE） is the main trend of the current vocational education, and non-commissioned officers subordinate to the nature of the military education of vocational education has become a consensus. CBE guide students to use non-commissioned officers to carry out the post office internships can effectively compensate for the lack of current teaching practice and improve the quality of teaching practice.展开更多
Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology,the computer-aided drug design techniques have been successfully applied in almost every stage...Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology,the computer-aided drug design techniques have been successfully applied in almost every stage of the drug discovery and development pipeline to speed up the process of research and reduce the cost and risk related to preclinical and clinical trials.Owing to the development of machine learning theory and the accumulation of pharmacological data, the artificial intelligence(AI) technology, as a powerful data mining tool, has cut a figure in various fields of the drug design, such as virtual screening,activity scoring, quantitative structure-activity relationship(QSAR) analysis, de novo drug design, and in silico evaluation of absorption, distribution, metabolism, excretion and toxicity(ADME/T) properties. Although it is still challenging to provide a physical explanation of the AI-based models, it indeed has been acting as a great power to help manipulating the drug discovery through the versatile frameworks. Recently, due to the strong generalization ability and powerful feature extraction capability,deep learning methods have been employed in predicting the molecular properties as well as generating the desired molecules,which will further promote the application of AI technologies in the field of drug design.展开更多
文摘This paper discussed a method to judge and to reject the mistake and error of the monitoring strategies for English teaching and learning, and alsopresented a classification of mistake and error according to the following factors： the definition and analysisofmistake and error.With the development of theanalysis theories, more attention has been paid to the characteristic and the principle of mistake and error in the second language teaching and learning. By analyzing the differences between mistake and error, the teachers and learners can get clear of the study of English and improve the ability of using English.
文摘Intemship positions are non-commissioned officers serving students with the knowledge and skills learned in school is based, went to a professional army posts counterparts learning and training, in practice, further temper professional skills, familiar with the work force characteristics, to achieve after graduation ＂Zero posts＂ lay a solid foundation, Competency-based education （Competence Based Education, referred CBE） is the main trend of the current vocational education, and non-commissioned officers subordinate to the nature of the military education of vocational education has become a consensus. CBE guide students to use non-commissioned officers to carry out the post office internships can effectively compensate for the lack of current teaching practice and improve the quality of teaching practice.
基金supported by the National Natural Science Foundation of China (21210003 and 81230076 to H.J., 81773634 to M.Z. and 81430084 to K.C.)the “Personalized Medicines-Molecular Signature-based Drug Discovery and Development”, Strategic Priority Research Program of the Chinese Academy of Sciences (XDA12050201 to M.Z.)+1 种基金National Key Research & Development Plan (2016YFC1201003 to M.Z.)the National Basic Research Program (2015CB910304 to X.L.)
文摘Thanks to the fast improvement of the computing power and the rapid development of the computational chemistry and biology,the computer-aided drug design techniques have been successfully applied in almost every stage of the drug discovery and development pipeline to speed up the process of research and reduce the cost and risk related to preclinical and clinical trials.Owing to the development of machine learning theory and the accumulation of pharmacological data, the artificial intelligence(AI) technology, as a powerful data mining tool, has cut a figure in various fields of the drug design, such as virtual screening,activity scoring, quantitative structure-activity relationship(QSAR) analysis, de novo drug design, and in silico evaluation of absorption, distribution, metabolism, excretion and toxicity(ADME/T) properties. Although it is still challenging to provide a physical explanation of the AI-based models, it indeed has been acting as a great power to help manipulating the drug discovery through the versatile frameworks. Recently, due to the strong generalization ability and powerful feature extraction capability,deep learning methods have been employed in predicting the molecular properties as well as generating the desired molecules,which will further promote the application of AI technologies in the field of drug design.
