To evaluate and compare the effect of hinge position and flap thickness on recovery rate of corneal sensation after (LASIK)-. Prospective, randomized clinical study. Forty eyes of 40 patients underwent LASIK to correc...To evaluate and compare the effect of hinge position and flap thickness on recovery rate of corneal sensation after (LASIK)-. Prospective, randomized clinical study. Forty eyes of 40 patients underwent LASIK to correct myopia ranging from-1.00 to-2.50 diopters. Corneal sensitivity was measured preoperatively and each month after surgery until recovery to preoperative level. The nasal-hinged ACS microkeratome (NH) with depth plates of 130 and 160 μ m and the superiorhinged Hansatome microkeratome (SH) with depth plates of 160 and 180 μ m were used for corneal flap creation. The eyes were divided into four groups according to the hinge position and depth plate (DP): group 1, NH and 130 μ m DP; group 2, NH and 160 μ m DP; group 3, SH and 160 μ m DP; group 4, SH and 180 μ m DP. Corneal sensitivity returned to preoperative level after 3.7 (± 0.4), 4.4 (± 0.6), 5.4 (± 0.8), and 5.8 (± 0.9) months, respectively, in groups 1, 2, 3, and 4. Statistically significant differences were found between groups 1 and 2, but not between groups 3 and 4. Corneal sensitivity gradually returned to preoperative levels in all groups. Sensitivity of the hinge area was higher than other areas at every time point. The results suggest that after LASIK, hinge position and flap thickness seem to be important factors in the rate of return of corneal sensitivity. A thin flap with a nasally placed hinge is associated with the most rapid recovery of corneal sensitivity.展开更多
目的探讨皮下组织蒂菱形皮瓣成形术治疗烧伤后瘢痕挛缩的效果。方法选取2019年10月至2022年10月莆田市第一医院烧伤整形科收治的烧伤后瘢痕挛缩患者共100例,按治疗方式不同分成研究组(50例)与对照组(50例),对照组采用游离皮片移植术,研...目的探讨皮下组织蒂菱形皮瓣成形术治疗烧伤后瘢痕挛缩的效果。方法选取2019年10月至2022年10月莆田市第一医院烧伤整形科收治的烧伤后瘢痕挛缩患者共100例,按治疗方式不同分成研究组(50例)与对照组(50例),对照组采用游离皮片移植术,研究组采用皮下组织蒂菱形皮瓣成形术,统计两组术后1年皮瓣成活率、瘢痕挛缩复发率,比较两组生活质量[生活质量综合评定问卷(Generic Quality of Life Inventory-74,GQOLI-74)]、并发症。结果术后1年,研究组(100.00%)皮瓣成活率与对照组(92.00%)比较差异有统计学意义(P<0.05),研究组(4.00%)瘢痕挛缩复发率较对照组(18.00%)更低(P<0.05);两组术后1年GQOLI-74评分升高(P<0.05),研究组较对照组更高(P<0.05);研究组(4.00%)并发症发生率较对照组(24.00%)更低(P<0.05)。结论皮下组织蒂菱形皮瓣成形术治疗烧伤后瘢痕挛缩皮瓣成活率较高,可降低瘢痕挛缩复发率、生活质量提高,降低并发症发生风险。展开更多
文摘To evaluate and compare the effect of hinge position and flap thickness on recovery rate of corneal sensation after (LASIK)-. Prospective, randomized clinical study. Forty eyes of 40 patients underwent LASIK to correct myopia ranging from-1.00 to-2.50 diopters. Corneal sensitivity was measured preoperatively and each month after surgery until recovery to preoperative level. The nasal-hinged ACS microkeratome (NH) with depth plates of 130 and 160 μ m and the superiorhinged Hansatome microkeratome (SH) with depth plates of 160 and 180 μ m were used for corneal flap creation. The eyes were divided into four groups according to the hinge position and depth plate (DP): group 1, NH and 130 μ m DP; group 2, NH and 160 μ m DP; group 3, SH and 160 μ m DP; group 4, SH and 180 μ m DP. Corneal sensitivity returned to preoperative level after 3.7 (± 0.4), 4.4 (± 0.6), 5.4 (± 0.8), and 5.8 (± 0.9) months, respectively, in groups 1, 2, 3, and 4. Statistically significant differences were found between groups 1 and 2, but not between groups 3 and 4. Corneal sensitivity gradually returned to preoperative levels in all groups. Sensitivity of the hinge area was higher than other areas at every time point. The results suggest that after LASIK, hinge position and flap thickness seem to be important factors in the rate of return of corneal sensitivity. A thin flap with a nasally placed hinge is associated with the most rapid recovery of corneal sensitivity.
文摘目的探讨皮下组织蒂菱形皮瓣成形术治疗烧伤后瘢痕挛缩的效果。方法选取2019年10月至2022年10月莆田市第一医院烧伤整形科收治的烧伤后瘢痕挛缩患者共100例,按治疗方式不同分成研究组(50例)与对照组(50例),对照组采用游离皮片移植术,研究组采用皮下组织蒂菱形皮瓣成形术,统计两组术后1年皮瓣成活率、瘢痕挛缩复发率,比较两组生活质量[生活质量综合评定问卷(Generic Quality of Life Inventory-74,GQOLI-74)]、并发症。结果术后1年,研究组(100.00%)皮瓣成活率与对照组(92.00%)比较差异有统计学意义(P<0.05),研究组(4.00%)瘢痕挛缩复发率较对照组(18.00%)更低(P<0.05);两组术后1年GQOLI-74评分升高(P<0.05),研究组较对照组更高(P<0.05);研究组(4.00%)并发症发生率较对照组(24.00%)更低(P<0.05)。结论皮下组织蒂菱形皮瓣成形术治疗烧伤后瘢痕挛缩皮瓣成活率较高,可降低瘢痕挛缩复发率、生活质量提高,降低并发症发生风险。