甘草次酸精氨酸盐的波谱学表征

As an important constituent of Glycyrrhiza uralensis Fisch.,glycyrrhetinic acid has been widely used in Chinese traditional medicine.In order to improve its water solubility and bio-avalability and to reduce its side effects,a new derivative of glycyrrhetinic acid,arginine glycyrrhetinate,was synthesized by the reaction of 18β-glycyrrhetinic acid with L-arginine.The chemical composition and structure of this new compound were determined by a series of spectral technology,including MS,NMR,UV and IR spectroscopy.This study will be useful to identification of compounds with similar structure and also be helpful to quality control during drug production.

11-脱氧甘草次酸衍生物的合成

本文报道了具有潜在药理活性和应用前景的11-脱氧甘草次酸酯、11-脱氧甘草次酸盐的合成方法。